Multimodal Magnetic Resonance and Near-Infrared-Fluorescent Imaging of Intraperitoneal Ovarian Cancer Using a Dual-Mode-Dual-Gadolinium Liposomal Contrast Agent.

abstract：:Although hepatitis B virus (HBV) infection is the leading cause of liver fibrosis (LF), the mechanisms underlying liver fibrotic progression remain unclear. Here, we investigated the gene expression profiles of HBV-related LF patients. Whole genome expression arrays were used to detect gene expression in liver biopsy ...

journal_title：Scientific reports

authors： Wang M,Gong Q,Zhang J,Chen L,Zhang Z,Lu L,Yu D,Han Y,Zhang D,Chen P,Zhang X,Yuan Z,Huang J,Zhang X

更新日期：2017-03-06 00:00:00

abstract：:Emission of the trace gas dimethylsulphide (DMS) from the ocean influences the chemical and optical properties of the atmosphere, and the olfactory landscape for foraging marine birds, turtles and mammals. DMS concentration has been seen to vary across seasons and latitudes with plankton taxonomy and activity, and fol...

journal_title：Scientific reports

authors： Royer SJ,Galí M,Mahajan AS,Ross ON,Pérez GL,Saltzman ES,Simó R

更新日期：2016-08-31 00:00:00

abstract：:Emerging evidence demonstrates the importance of sufficient vitamin D (1α, 25-dihydroxyvitamin D3) levels during early life stage development with deficiencies associated with long-term effects into adulthood. While vitamin D has traditionally been associated with mineral ion homeostasis, accumulating evidence suggest...

journal_title：Scientific reports

authors： Knuth MM,Mahapatra D,Jima D,Wan D,Hammock BD,Law M,Kullman SW

更新日期：2020-09-29 00:00:00

abstract：:Cotton leaf curl disease (CLCuD), caused by cotton leaf curl viruses (CLCuVs), is among the most devastating diseases in cotton. While the widely cultivated cotton species Gossypium hirsutum is generally susceptible, the diploid species G. arboreum is a natural source for resistance against CLCuD. However, the influen...

journal_title：Scientific reports

authors： Naqvi RZ,Zaidi SS,Akhtar KP,Strickler S,Woldemariam M,Mishra B,Mukhtar MS,Scheffler BE,Scheffler JA,Jander G,Mueller LA,Asif M,Mansoor S

更新日期：2017-11-21 00:00:00

abstract：:Ample evidence indicates that obesity causes dysfunctions in the lung. Previous studies also show that cholinergic anti-inflammatory pathways play crucial roles in obesity-induced chronic inflammation via α7 nicotinic acetylcholine receptor (α7nAChR) signaling. However, it remains unclear whether and how obesity affec...

journal_title：Scientific reports

authors： Qi Y,Si D,Zhu L,Qi Y,Wu Z,Chen D,Yang Y

更新日期：2020-10-27 00:00:00

abstract：:Commercial Pt/C anodes of direct formic acid fuel cells (DFAFCs) get rapidly poisoned by in-situ generated CO intermediates from formic acid non-faradaic dissociation. We succeeded in increasing the Pt nanoparticles (PtNPs) stability and activity for formic acid oxidation (DFAFCs anodic reaction) by embedding them ins...

journal_title：Scientific reports

authors： El-Nagar GA,Hassan MA,Lauermann I,Roth C

更新日期：2017-12-19 00:00:00

abstract：:When coming to identify new 2D materials, our intuition would suggest us to look from layered instead of 3D materials. However, since graphite can be hypothetically derived from diamond by stretching it along its [111] axis, many 3D materials can also potentially be explored as new candidates for 2D materials. Using a...

journal_title：Scientific reports

authors： Wang J,Zhang Y

更新日期：2016-04-19 00:00:00

abstract：:The performance of most error-correction (EC) algorithms that operate on genomics reads is dependent on the proper choice of its configuration parameters, such as the value of k in k-mer based techniques. In this work, we target the problem of finding the best values of these configuration parameters to optimize error...

journal_title：Scientific reports

authors： Abdallah M,Mahgoub A,Ahmed H,Chaterji S

更新日期：2019-11-06 00:00:00

abstract：:The presence of genetically modified organisms (GMO) is commonly assessed using real-time PCR methods targeting the most common transgenic elements found in GMOs. Once the presence of GM material has been established using these screening methods, GMOs are further identified using a battery of real-time PCR methods, e...

journal_title：Scientific reports

authors： Boutigny AL,Fioriti F,Rolland M

更新日期：2020-09-15 00:00:00

abstract：:Meaningful, reliable and valid mRNA expression analyses by real-time quantitative PCR (RT-qPCR) can only be achieved, if suitable reference genes are chosen for normalization and if appropriate RT-qPCR quality standards are met. Human periodontal ligament (hPDL) fibroblasts play a major mediating role in orthodontic t...

journal_title：Scientific reports

authors： Kirschneck C,Batschkus S,Proff P,Köstler J,Spanier G,Schröder A

更新日期：2017-11-07 00:00:00

abstract：:We have investigated the valley Chern number and gapless edge states in wide-gap semiconductor SiC and BN monolayers by using the density functional theory calculations. We found that while SiC monolayer has a non-quantized valley Chern number due to a partial mixing of the Berry curvature peaks pertaining to the oppo...

journal_title：Scientific reports

authors： Lee KW,Lee CE

更新日期：2020-03-19 00:00:00

abstract：:Despite the initiative by WHO and other international organizations to eliminate HCV in the medium term, hepatitis C infection is still a major public health problem. Even non-injecting drugs users who engage in harmful or addictive drug use are at greater risk of acquiring the infection, when compared to the general ...

journal_title：Scientific reports

authors： Coutinho C,Bastos LS,da Mota JC,Toledo L,Costa K,Bertoni N,Bastos FI

更新日期：2019-01-24 00:00:00

abstract：:Sepsis induced cardiac dysfunction (SIC) is a severe complication to sepsis which significantly worsens patient outcomes. It is known that bacteria have the capacity to release outer membrane vesicles (OMVs), which are nano-sized bilayered vesicles composed of lipids and proteins, that can induce a fatal inflammatory ...

journal_title：Scientific reports

authors： Svennerholm K,Park KS,Wikström J,Lässer C,Crescitelli R,Shelke GV,Jang SC,Suzuki S,Bandeira E,Olofsson CS,Lötvall J

更新日期：2017-12-12 00:00:00

abstract：:It is indicated that lipids profiles are associated with carotid plaque and Atherosclerosis. However, studies about the relationship between serum lipid profiles and carotid plaque composition in Chinese Population is limited. We conducted a cross-sectional study among 3,214 participants between January 2015 and Decem...

journal_title：Scientific reports

authors： Liu Y,Zhu Y,Jia W,Sun D,Zhao L,Zhang C,Wang C,Chen G,Fu S,Bo Y,Xing Y

更新日期：2019-11-29 00:00:00

abstract：:Applying a circular economy approach, this research explores the use of cheese whey permeate (CWP), by-product of whey ultrafiltration, as cheap substrate for the production of bacterial cellulose (BC) and Sakacin-A, to be used in an antimicrobial packaging material. BC from the acetic acid bacterium Komagataeibacter ...

journal_title：Scientific reports

authors： Rollini M,Musatti A,Cavicchioli D,Bussini D,Farris S,Rovera C,Romano D,De Benedetti S,Barbiroli A

更新日期：2020-12-07 00:00:00

abstract：:Obesity-induced adipose-tissue dysfunction is a critical contributor to the pathogenesis of nonalcoholic fatty liver disease (NAFLD). B cell-activating factor (BAFF) is an adipokine related to impaired insulin sensitivity, and the serum BAFF concentration is associated with NAFLD severity. In this study, we aimed to d...

journal_title：Scientific reports

authors： Nakamura Y,Abe M,Kawasaki K,Miyake T,Watanabe T,Yoshida O,Hirooka M,Matsuura B,Hiasa Y

更新日期：2019-01-30 00:00:00

abstract：:Macrophages are potent immune cells with well-established roles in the response to stress, injury, infection and inflammation. The classically activated macrophages (M1) are induced by lipopolysaccharide (LPS) and express a wide range of pro-inflammatory genes. M2 macrophages are induced by T helper type 2 cytokines s...

journal_title：Scientific reports

authors： Moraes LA,Kar S,Foo SL,Gu T,Toh YQ,Ampomah PB,Sachaphibulkij K,Yap G,Zharkova O,Lukman HM,Fairhurst AM,Kumar AP,Lim LHK

更新日期：2017-12-20 00:00:00

abstract：:In photosynthesis Ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) catalyses the often rate limiting CO2-fixation step in the Calvin cycle. This makes Rubisco both the gatekeeper for carbon entry into the biosphere and a target for functional improvement to enhance photosynthesis and plant growth. Encumbering...

journal_title：Scientific reports

authors： Wilson RH,Alonso H,Whitney SM

更新日期：2016-03-01 00:00:00

abstract：:There is an unmet need for treatments to reduce abdominal aortic aneurysm (AAA) progression. Vascular smooth muscle cell (VSMC) apoptosis precipitates AAA formation, whereas VSMC proliferation repairs the vessel wall. We previously demonstrated that over-expression of EC4-Fc (truncated N-cadherin), or deletion of matr...

journal_title：Scientific reports

authors： Lyon CA,Williams H,Bianco R,Simmonds SJ,Brown BA,Wadey KS,Smith FCT,Johnson JL,George SJ

更新日期：2017-12-11 00:00:00

abstract：:We have recently reported that Kupffer cells consist of two subsets, radio-resistant resident CD68+ Kupffer cells and radio-sensitive recruited CD11b+ Kupffer cells/macrophages (Mφs). Non-alcoholic steatohepatitis (NASH) is characterized not only by hepatic steatosis but also chronic inflammation and fibrosis. In the ...

journal_title：Scientific reports

authors： Nakashima H,Nakashima M,Kinoshita M,Ikarashi M,Miyazaki H,Hanaka H,Imaki J,Seki S

更新日期：2016-10-06 00:00:00

abstract：:The efficacy and safety of misoprostol alone for missed abortion varied with different regimens. To evaluate existing evidence for the medical management of missed abortion using misoprostol, we undertook a comprehensive review and meta-analysis. The electronic literature search was conducted using PubMed, the Cochran...

journal_title：Scientific reports

authors： Wu HL,Marwah S,Wang P,Wang QM,Chen XW

更新日期：2017-05-10 00:00:00

abstract：:Work stress is a risk factor for cardio-metabolic diseases, but few large-scale studies have examined the clinical profile of individuals with work stress. To address this limitation, we conducted a cross-sectional study including 43,593 working adults from a French population-based sample aged 18-72 years (the CONSTA...

journal_title：Scientific reports

authors： Magnusson Hanson LL,Westerlund H,Goldberg M,Zins M,Vahtera J,Hulvej Rod N,Stenholm S,Steptoe A,Kivimäki M

更新日期：2017-08-24 00:00:00

abstract：:There are many types of autoregressive patterns in financial time series, and they form a transmission process. Here, we define autoregressive patterns quantitatively through an econometrical regression model. We present a computational algorithm that sets the autoregressive patterns as nodes and transmissions between...

journal_title：Scientific reports

authors： Gao X,An H,Fang W,Huang X,Li H,Zhong W

更新日期：2014-09-05 00:00:00

abstract：:A polymer coating as polycaprolactone (PCL) is applied to improve the initial corrosion resistance of biodegradable magnesium. In addition, plasma electrolytic oxidation (PEO) is performed to increase adhesion between the polymer and the metal. However, when a complex-shaped material such as a screw is implanted in a ...

journal_title：Scientific reports

authors： Kim YK,Lee KB,Kim SY,Jang YS,Kim JH,Lee MH

更新日期：2018-09-05 00:00:00

abstract：:Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases, yet current therapeutic treatments are inadequate due to a complex disease pathogenesis. The plant polyphenol apigenin has been shown to have anti-inflammatory and neuroprotective properties in a number of cell and animal models; however...

journal_title：Scientific reports

authors： Balez R,Steiner N,Engel M,Muñoz SS,Lum JS,Wu Y,Wang D,Vallotton P,Sachdev P,O'Connor M,Sidhu K,Münch G,Ooi L

更新日期：2016-08-12 00:00:00

abstract：:Raman spectroscopy is a powerful analytical method that allows deposited and/or immobilized cells to be evaluated without complex sample preparation or labeling. However, a main limitation of Raman spectroscopy in cell analysis is the extremely weak Raman intensity that results in low signal to noise ratios. Therefore...

journal_title：Scientific reports

authors： Mikoliunaite L,Rodriguez RD,Sheremet E,Kolchuzhin V,Mehner J,Ramanavicius A,Zahn DR

更新日期：2015-08-27 00:00:00

abstract：:A three-dimensional multiscale modeling framework is developed to analyze the failure procedure of radially aligned zinc oxide (ZnO) enhanced single fiber composites (SFC) under tensile loading to understand the interfacial improvement between the fiber and the matrix. The model introduces four levels in the computati...

journal_title：Scientific reports

authors： Marashizadeh P,Abshirini M,Wang J,C Saha M,Liu Y

更新日期：2019-12-27 00:00:00

abstract：:Data on post stroke outcomes in developing countries are scarce due to uncoordinated healthcare delivery systems. In Malaysia, the national stroke clinical practice guideline does not address transfer of care and longer term post stroke care beyond tertiary care. Hence, post stroke care delivery may be delivered at ei...

journal_title：Scientific reports

authors： Abdul Aziz AF,Ali MF,Yusof MF,Che' Man Z,Sulong S,Aljunid SM

更新日期：2018-12-19 00:00:00

abstract：:Vitamin D and parathyroid hormone (PTH) regulate mineral metabolism and are required to maintain calcium levels. Vitamin D deficiency is common, particularly during pregnancy, and has been associated with hypertensive disorders of pregnancy. We sought to determine whether maternal 25(OH)D, PTH and calcium concentratio...

journal_title：Scientific reports

authors： Santorelli G,Whitelaw D,Farrar D,West J,Lawlor DA

更新日期：2019-02-04 00:00:00

abstract：:Antibody-drug conjugates (ADCs) are attractive in cancer therapy because they can directly bind to cancer cells and provide anticancer activity. To kill cancer cells with ADCs, the target antigens are required not only to be highly and/or selectively expressed on cancer cells but also internalized by the cells. CD239,...

journal_title：Scientific reports

authors： Kikkawa Y,Enomoto-Okawa Y,Fujiyama A,Fukuhara T,Harashima N,Sugawara Y,Negishi Y,Katagiri F,Hozumi K,Nomizu M,Ito Y

更新日期：2018-04-26 00:00:00