Association Between Trauma Center Type and Mortality Among Injured Adolescent Patients.

Abstract:

IMPORTANCE:Although data obtained from regional trauma systems demonstrate improved outcomes for children treated at pediatric trauma centers (PTCs) compared with those treated at adult trauma centers (ATCs), differences in mortality have not been consistently observed for adolescents. Because trauma is the leading cause of death and acquired disability among adolescents, it is important to better define differences in outcomes among injured adolescents by using national data. OBJECTIVES:To use a national data set to compare mortality of injured adolescents treated at ATCs, PTCs, or mixed trauma centers (MTCs) that treat both pediatric and adult trauma patients and to determine the final discharge disposition of survivors at different center types. DESIGN, SETTING, AND PARTICIPANTS:Data from level I and II trauma centers participating in the 2010 National Trauma Data Bank (January 1 to December 31, 2010) were used to create multilevel models accounting for center-specific effects to evaluate the association of center characteristics (PTC, ATC, or MTC) on mortality among patients aged 15 to 19 years who were treated for a blunt or penetrating injury. The models controlled for sex; mechanism of injury (blunt vs penetrating); injuries sustained, based on the Abbreviated Injury Scale scores (post-dot values <3 or ≥3 by body region); initial systolic blood pressure; and Glasgow Coma Scale scores. Missing data were managed using multiple imputation, accounting for multilevel data structure. Data analysis was conducted from January 15, 2013, to March 15, 2016. EXPOSURES:Type of trauma center. MAIN OUTCOMES AND MEASURES:Mortality at each center type. RESULTS:Among 29 613 injured adolescents (mean [SD] age, 17.3 [1.4] years; 72.7% male), most were treated at ATCs (20 402 [68.9%]), with the remainder at MTCs (7572 [25.6%]) or PTCs (1639 [5.5%]). Adolescents treated at PTCs were more likely to be injured by a blunt than penetrating injury mechanism (91.4%) compared with those treated at ATCs (80.4%) or MTCs (84.6%). Mortality was higher among adolescents treated at ATCs and MTCs than those treated at PTCs (3.2% and 3.5% vs 0.4%; P < .001). The adjusted odds of mortality were higher at ATCs (odds ratio, 4.19; 95% CI, 1.30-13.51) and MTCs (odds ratio, 6.68; 95% CI, 2.03-21.99) compared with PTCs but was not different between level I and II centers (odds ratio, 0.76; 95% CI, 0.59-0.99). CONCLUSION AND RELEVANCE:Mortality among injured adolescents was lower among those treated at PTCs, compared with those treated at ATCs and MTCs. Defining resource and patient features that account for these observed differences is needed to optimize adolescent outcomes after injury.

journal_name

JAMA Pediatr

journal_title

JAMA pediatrics

authors

Webman RB,Carter EA,Mittal S,Wang J,Sathya C,Nathens AB,Nance ML,Madigan D,Burd RS

doi

10.1001/jamapediatrics.2016.0805

subject

Has Abstract

pub_date

2016-08-01 00:00:00

pages

780-6

issue

8

eissn

2168-6203

issn

2168-6211

pii

2529985

journal_volume

170

pub_type

杂志文章,多中心研究
  • Respiratory infections in early life and the development of islet autoimmunity in children at increased type 1 diabetes risk: evidence from the BABYDIET study.

    abstract:IMPORTANCE:There is evidence for a role of infections within the pathogenesis of islet autoimmunity and type 1 diabetes mellitus (T1D), but previous studies did not allow assessment of potential critical time windows in this context. OBJECTIVE:To examine whether early, short-term, or cumulative exposures to episodes o...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章

    doi:10.1001/jamapediatrics.2013.158

    authors: Beyerlein A,Wehweck F,Ziegler AG,Pflueger M

    更新日期:2013-09-01 00:00:00

  • Hospital Injury Encounters of Children Identified by a Predictive Risk Model for Screening Child Maltreatment Referrals: Evidence From the Allegheny Family Screening Tool.

    abstract:Importance:Nearly 6 million children are reported as allegedly experiencing abuse or neglect in the US annually. Child protection agencies are increasingly turning to automated predictive risk models (PRMs) that mine information found in routinely collected administrative data and estimate a likelihood that an individu...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章

    doi:10.1001/jamapediatrics.2020.2770

    authors: Vaithianathan R,Putnam-Hornstein E,Chouldechova A,Benavides-Prado D,Berger R

    更新日期:2020-08-03 00:00:00

  • Associations Between Hydration Status, Intravenous Fluid Administration, and Outcomes of Patients Infected With Shiga Toxin-Producing Escherichia coli: A Systematic Review and Meta-analysis.

    abstract:Importance:The associations between hydration status, intravenous fluid administration, and outcomes of patients infected with Shiga toxin-producing Escherichia coli (STEC) remain unclear. Objective:To determine the relationship between hydration status, the development and severity of hemolytic uremic syndrome (HUS),...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章,meta分析,评审

    doi:10.1001/jamapediatrics.2016.2952

    authors: Grisaru S,Xie J,Samuel S,Hartling L,Tarr PI,Schnadower D,Freedman SB,Alberta Provincial Pediatric Enteric Infection Team.

    更新日期:2017-01-01 00:00:00

  • Collaborative centralized reminder/recall notification to increase immunization rates among young children: a comparative effectiveness trial.

    abstract:IMPORTANCE:Reminder/recall notifications used by primary care practices increase the rates of childhood immunizations, but fewer than 20% of primary care practitioners nationally deliver such reminders. A reminder/recall notification conducted centrally by health departments in collaboration with primary care practices...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1001/jamapediatrics.2014.3670

    authors: Kempe A,Saville AW,Dickinson LM,Beaty B,Eisert S,Gurfinkel D,Brewer S,Shull H,Herrero D,Herlihy R

    更新日期:2015-04-01 00:00:00

  • Cost-effectiveness of Antenatal Corticosteroid Therapy vs No Therapy in Women at Risk of Late Preterm Delivery: A Secondary Analysis of a Randomized Clinical Trial.

    abstract:Importance:Administration of corticosteroids to women at high risk for delivery in the late preterm period (34-36 weeks' gestation) improves short-term neonatal outcomes. The cost implications of this intervention are not known. Objective:To compare the cost-effectiveness of treatment with antenatal corticosteroids wi...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1001/jamapediatrics.2019.0032

    authors: Gyamfi-Bannerman C,Zupancic JAF,Sandoval G,Grobman WA,Blackwell SC,Tita ATN,Reddy UM,Jain L,Saade GR,Rouse DJ,Iams JD,Clark EAS,Thorp JM Jr,Chien EK,Peaceman AM,Gibbs RS,Swamy GK,Norton ME,Casey BM,Caritis SN,Tolo

    更新日期:2019-05-01 00:00:00

  • Estimating impacts of a breakfast in the classroom program on school outcomes.

    abstract:IMPORTANCE:Short-term impacts of breakfast consumption on diet quality and cognitive functioning have been reported, but more evidence is needed to draw causal inferences about long-term impacts of school breakfast on indicators of school engagement and academic achievement. OBJECTIVE:To estimate the impact of a Break...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1001/jamapediatrics.2014.2042

    authors: Anzman-Frasca S,Djang HC,Halmo MM,Dolan PR,Economos CD

    更新日期:2015-01-01 00:00:00

  • Association of Gestational Age at Birth With Brain Morphometry.

    abstract:Importance:Preterm and postterm births are associated with adverse neuropsychiatric outcomes. However, it remains unclear whether variation of gestational age within the 37- to 42-week range of term deliveries is associated with neurodevelopment. Objective:To investigate the association of gestational age at birth (GA...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章

    doi:10.1001/jamapediatrics.2020.2991

    authors: El Marroun H,Zou R,Leeuwenburg MF,Steegers EAP,Reiss IKM,Muetzel RL,Kushner SA,Tiemeier H

    更新日期:2020-09-21 00:00:00

  • Characterizing the Pattern of Anomalies in Congenital Zika Syndrome for Pediatric Clinicians.

    abstract:Importance:Zika virus infection can be prenatally passed from a pregnant woman to her fetus. There is sufficient evidence to conclude that intrauterine Zika virus infection is a cause of microcephaly and serious brain anomalies, but the full spectrum of anomalies has not been delineated. To inform pediatric clinicians ...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章,评审

    doi:10.1001/jamapediatrics.2016.3982

    authors: Moore CA,Staples JE,Dobyns WB,Pessoa A,Ventura CV,Fonseca EB,Ribeiro EM,Ventura LO,Neto NN,Arena JF,Rasmussen SA

    更新日期:2017-03-01 00:00:00

  • Long-term Cognitive and Health Outcomes of School-Aged Children Who Were Born Late-Term vs Full-Term.

    abstract:IMPORTANCE:Late-term gestation (defined as the 41st week of pregnancy) is associated with increased risk of perinatal health complications. It is not known to what extent late-term gestation is associated with long-term cognitive and physical outcomes. Information about long-term outcomes may influence physician and pa...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章

    doi:10.1001/jamapediatrics.2016.0238

    authors: Figlio DN,Guryan J,Karbownik K,Roth J

    更新日期:2016-08-01 00:00:00

  • Youth problem behaviors 8 years after implementing the communities that care prevention system: a community-randomized trial.

    abstract:IMPORTANCE:Community-based efforts to prevent adolescent problem behaviors are essential to promote public health and achieve collective impact community wide. OBJECTIVE To test whether the Communities That Care (CTC) prevention system reduced levels of risk and adolescent problem behaviors community wide 8 years after...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1001/jamapediatrics.2013.4009

    authors: Hawkins JD,Oesterle S,Brown EC,Abbott RD,Catalano RF

    更新日期:2014-02-01 00:00:00

  • A statewide Medicaid enhanced prenatal care program: impact on birth outcomes.

    abstract:IMPORTANCE:Policy makers and practitioners need rigorous evaluations of state-based Medicaid enhanced prenatal care programs that provide home visiting to guide improvements and inform future investments. Effects on adverse birth outcomes are of particular interest. OBJECTIVE:To test if participation in the Michigan s...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章

    doi:10.1001/jamapediatrics.2013.4347

    authors: Roman L,Raffo JE,Zhu Q,Meghea CI

    更新日期:2014-03-01 00:00:00

  • Assessment of Maternal and Neonatal Cord Blood SARS-CoV-2 Antibodies and Placental Transfer Ratios.

    abstract:Importance:Maternally derived antibodies are a key element of neonatal immunity. Understanding the dynamics of maternal antibody responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy and subsequent transplacental antibody transfer can inform neonatal management as well as ...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章

    doi:10.1001/jamapediatrics.2021.0038

    authors: Flannery DD,Gouma S,Dhudasia MB,Mukhopadhyay S,Pfeifer MR,Woodford EC,Triebwasser JE,Gerber JS,Morris JS,Weirick ME,McAllister CM,Bolton MJ,Arevalo CP,Anderson EM,Goodwin EC,Hensley SE,Puopolo KM

    更新日期:2021-01-29 00:00:00

  • Modifiable determinants of serum 25-hydroxyvitamin D status in early childhood: opportunities for prevention.

    abstract::OBJECTIVES To determine the effect of modifiable dietary intake variables (current vitamin D supplementation and daily cow's milk intake) on 25-hydroxyvitamin D level in early childhood and to evaluate the relationship between these modifiable dietary factors and other largely nonmodifiable determinants of vitamin D s...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章

    doi:10.1001/2013.jamapediatrics.226

    authors: Maguire JL,Birken CS,Khovratovich M,Degroot J,Carsley S,Thorpe KE,Mamdani M,Parkin PC,TARGet Kids! Collaboration.

    更新日期:2013-03-01 00:00:00

  • Association of Age With Risk of Hospitalization for Respiratory Syncytial Virus in Preterm Infants With Chronic Lung Disease.

    abstract:Importance:It is unknown whether the age threshold (≤24 months) for preterm infants with chronic lung disease (CLD) to receive immunoprophylaxis for respiratory syncytial virus (RSV) as currently recommended by American Academy of Pediatrics guidelines correctly identified infants at higher risk for hospitalization for...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章

    doi:10.1001/jamapediatrics.2017.3792

    authors: Winterstein AG,Choi Y,Meissner HC

    更新日期:2018-02-01 00:00:00

  • Obesity Genes and Weight Loss During Lifestyle Intervention in Children With Obesity.

    abstract:Importance:Genome-wide association studies have identified genetic loci influencing obesity risk in children. However, the importance of these loci in the associations with weight reduction through lifestyle interventions has not been investigated in large intervention trials. Objective:To evaluate the associations be...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章

    doi:10.1001/jamapediatrics.2020.5142

    authors: Heitkamp M,Siegrist M,Molnos S,Brandmaier S,Wahl S,Langhof H,Grallert H,Halle M

    更新日期:2021-01-01 00:00:00

  • Association between admission temperature and mortality and major morbidity in preterm infants born at fewer than 33 weeks' gestation.

    abstract:IMPORTANCE:Neonatal hypothermia has been associated with higher mortality and morbidity; therefore, thermal control following delivery is an essential part of neonatal care. Identifying the ideal body temperature in preterm neonates in the first few hours of life may be helpful to reduce the risk for adverse outcomes. ...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章

    doi:10.1001/jamapediatrics.2015.0277

    authors: Lyu Y,Shah PS,Ye XY,Warre R,Piedboeuf B,Deshpandey A,Dunn M,Lee SK,Canadian Neonatal Network.

    更新日期:2015-04-01 00:00:00

  • Assessment of C-Reactive Protein Diagnostic Test Accuracy for Late-Onset Infection in Newborn Infants: A Systematic Review and Meta-analysis.

    abstract:Importance:Rapid and accurate diagnosis of late-onset infection in newborn infants could inform treatment decisions and avoid unnecessary administration of antibiotics. Objective:To compare the accuracy of serum C-reactive protein (CRP) with that of microbiological blood culture for diagnosing late-onset infection in ...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章,meta分析

    doi:10.1001/jamapediatrics.2019.5669

    authors: Brown JVE,Meader N,Wright K,Cleminson J,McGuire W

    更新日期:2020-03-01 00:00:00

  • Association of Team Sports Participation With Long-term Mental Health Outcomes Among Individuals Exposed to Adverse Childhood Experiences.

    abstract:Importance:Adverse childhood experiences (ACEs) are associated with long-term poor mental health. Less is known about factors that improve long-term mental health among those with ACEs. Objective:To evaluate, among those exposed to ACEs, whether team sports participation during adolescence is associated with better me...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章

    doi:10.1001/jamapediatrics.2019.1212

    authors: Easterlin MC,Chung PJ,Leng M,Dudovitz R

    更新日期:2019-07-01 00:00:00

  • Comparative Effectiveness and Safety of Cognitive Behavioral Therapy and Pharmacotherapy for Childhood Anxiety Disorders: A Systematic Review and Meta-analysis.

    abstract:Importance:Childhood anxiety is common. Multiple treatment options are available, but existing guidelines provide inconsistent advice on which treatment to use. Objectives:To evaluate the comparative effectiveness and adverse events of cognitive behavioral therapy (CBT) and pharmacotherapy for childhood anxiety disord...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章,meta分析,评审

    doi:10.1001/jamapediatrics.2017.3036

    authors: Wang Z,Whiteside SPH,Sim L,Farah W,Morrow AS,Alsawas M,Barrionuevo P,Tello M,Asi N,Beuschel B,Daraz L,Almasri J,Zaiem F,Larrea-Mantilla L,Ponce OJ,LeBlanc A,Prokop LJ,Murad MH

    更新日期:2017-11-01 00:00:00

  • Risk for cerebral palsy in infants with total serum bilirubin levels at or above the exchange transfusion threshold: a population-based study.

    abstract:IMPORTANCE:Exchange transfusion is recommended for newborns with total serum bilirubin (TSB) levels thought to place them at risk for cerebral palsy (CP). However, the excess risk for CP among these infants is unknown. OBJECTIVE:To quantify the risks for CP and CP consistent with kernicterus that are associated with h...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章

    doi:10.1001/jamapediatrics.2014.3036

    authors: Wu YW,Kuzniewicz MW,Wickremasinghe AC,Walsh EM,Wi S,McCulloch CE,Newman TB

    更新日期:2015-03-01 00:00:00

  • Examination of the Pattern of Growth of Cerebral Tissue Volumes From Hospital Discharge to Early Childhood in Very Preterm Infants.

    abstract:IMPORTANCE:Smaller cerebral volumes at hospital discharge in very preterm (VPT) infants are associated with poor neurobehavioral outcomes. Brain growth from the newborn period to middle childhood has not been explored because longitudinal data have been lacking. OBJECTIVES:To examine the pattern of growth of cerebral ...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章

    doi:10.1001/jamapediatrics.2016.0781

    authors: Monson BB,Anderson PJ,Matthews LG,Neil JJ,Kapur K,Cheong JL,Doyle LW,Thompson DK,Inder TE

    更新日期:2016-08-01 00:00:00

  • Relationship between peer victimization, cyberbullying, and suicide in children and adolescents: a meta-analysis.

    abstract:IMPORTANCE:Peer victimization is related to an increased chance of suicidal ideation and suicide attempts among children and adolescents. OBJECTIVE To examine the relationship between peer victimization and suicidal ideation or suicide attempts using meta-analysis. DATA SOURCES Ovid MEDLINE, PsycINFO, and Web of Scienc...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章,meta分析

    doi:10.1001/jamapediatrics.2013.4143

    authors: van Geel M,Vedder P,Tanilon J

    更新日期:2014-05-01 00:00:00

  • Pragmatic trial of health care technologies to improve adherence to pediatric asthma treatment: a randomized clinical trial.

    abstract:IMPORTANCE:Most patients with asthma take fewer than half of prescribed doses of controller medication. Interventions to improve adherence have typically been costly, impractical, and at best only minimally successful. OBJECTIVE:To test a speech recognition (SR) intervention to improve adherence to pediatric asthma co...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1001/jamapediatrics.2014.3280

    authors: Bender BG,Cvietusa PJ,Goodrich GK,Lowe R,Nuanes HA,Rand C,Shetterly S,Tacinas C,Vollmer WM,Wagner N,Wamboldt FS,Xu S,Magid DJ

    更新日期:2015-04-01 00:00:00

  • Probiotics for Children With Recurrent Abdominal Pain.

    abstract:Clinical Question:Do dietary interventions, such as probiotics, improve pain in children with recurrent abdominal pain? Clinical Application:Compared with placebo, children who were treated with probiotic preparations were more likely to experience improvement in pain in the short term (odds ratio, 1.63; 95% CI, 1.07-...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章

    doi:10.1001/jamapediatrics.2018.4575

    authors: Newlove-Delgado T,Abbott RA,Martin AE

    更新日期:2019-02-01 00:00:00

  • Placebo vs Amoxicillin for Nonsevere Fast-Breathing Pneumonia in Malawian Children Aged 2 to 59 Months: A Double-blind, Randomized Clinical Noninferiority Trial.

    abstract:Importance:Pneumonia is the leading infectious killer of children. Rigorous evidence supporting antibiotic treatment of children with nonsevere fast-breathing pneumonia in low-resource African settings is lacking. Objective:To assess whether treatment with placebo for nonsevere fast-breathing pneumonia is substantivel...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1001/jamapediatrics.2018.3407

    authors: Ginsburg AS,Mvalo T,Nkwopara E,McCollum ED,Ndamala CB,Schmicker R,Phiri A,Lufesi N,Izadnegahdar R,May S

    更新日期:2019-01-01 00:00:00

  • Comparison of high-frequency oscillatory ventilation and conventional mechanical ventilation in pediatric respiratory failure.

    abstract:IMPORTANCE:Outcomes associated with use of high-frequency oscillatory ventilation (HFOV) in children with acute respiratory failure have not been established. OBJECTIVE:To compare the outcomes of HFOV with those of conventional mechanical ventilation (CMV) in children with acute respiratory failure. DESIGN, SETTING, ...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1001/jamapediatrics.2013.4463

    authors: Gupta P,Green JW,Tang X,Gall CM,Gossett JM,Rice TB,Kacmarek RM,Wetzel RC

    更新日期:2014-03-01 00:00:00

  • Association Between Fluid Balance and Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis.

    abstract:Importance:After initial resuscitation, critically ill children may accumulate fluid and develop fluid overload. Accruing evidence suggests that fluid overload contributes to greater complexity of care and worse outcomes. Objective:To describe the methods to measure fluid balance, define fluid overload, and evaluate t...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章,meta分析

    doi:10.1001/jamapediatrics.2017.4540

    authors: Alobaidi R,Morgan C,Basu RK,Stenson E,Featherstone R,Majumdar SR,Bagshaw SM

    更新日期:2018-03-01 00:00:00

  • A Content Analysis of Mental Health Discourse in Popular Rap Music.

    abstract:Importance:Rap artists are among the most recognizable celebrities in the US, serving as role models to an increasingly diverse audience of listeners. Through their lyrics, these artists have the potential to shape mental health discourse and reduce stigma. Objective:To investigate the prevalence and nature of mental ...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章

    doi:10.1001/jamapediatrics.2020.5155

    authors: Kresovich A,Reffner Collins MK,Riffe D,Carpentier FRD

    更新日期:2020-12-07 00:00:00

  • Efficacy and safety of histamine-2 receptor antagonists.

    abstract:IMPORTANCE:Histamine-2 receptor antagonists (H2RAs) are frequently used in the treatment of gastroesophageal reflux disease (GERD) in children; however, their efficacy and safety is questionable. OBJECTIVE:To systematically review the literature to assess the efficacy and safety of H2RAs in pediatric GERD. EVIDENCE R...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章,评审

    doi:10.1001/jamapediatrics.2014.1273

    authors: van der Pol R,Langendam M,Benninga M,van Wijk M,Tabbers M

    更新日期:2014-10-01 00:00:00

  • Impact of specific medical interventions in early childhood on increasing the prevalence of later intellectual disability.

    abstract:IMPORTANCE:For the past 100 years, medicine in industrialized nations has become increasingly focused on specific medical interventions designed to improve the health of individual patients. Substantial evidence suggests that broader improvements in public health, nutrition, and economic well-being are more salient tha...

    journal_title:JAMA pediatrics

    pub_type: 杂志文章

    doi:10.1001/jamapediatrics.2013.1379

    authors: Brosco JP,Sanders LM,Dowling M,Guez G

    更新日期:2013-06-01 00:00:00