Abstract:
Importance:It is unknown whether the age threshold (≤24 months) for preterm infants with chronic lung disease (CLD) to receive immunoprophylaxis for respiratory syncytial virus (RSV) as currently recommended by American Academy of Pediatrics guidelines correctly identified infants at higher risk for hospitalization for RSV. Objective:To determine the age when the risk of hospitalization for RSV among preterm infants with CLD becomes equivalent to the risk for healthy, 1-month-old term infants who do not qualify for immunoprophylaxis. Design, Setting, and Participants:A retrospective cohort study was conducted of 1 018 593 healthy term infants and 5181 preterm infants with CLD using Medicaid billing records (Medicaid Analytic eXtract files) from January 1, 1999, to December 31, 2010, linked to Florida and Texas birth and death certificates. Exposures:Age-trend discrete time logistic regression models within a survival analysis framework were developed, adjusting for covariates including the use of immunoprophylaxis, to compare the risk of hospitalization of preterm infants (<32 weeks' gestational age) with CLD at 3 through 34 months of age with the risk of hospitalization of term infants (37-41 weeks' gestational age) at 1 month of age. Main Outcomes and Measures:Age at which risk of hospitalization for RSV among preterm infants with CLD equals the risk for healthy term infants at age 1 month. Results:The study cohort included 1 018 593 healthy term infants and 5181 preterm infants with CLD; because patients could reenter the cohort for a second or third season, the total study cohort consisted of 1 880 531 healthy term infant-seasons (926 206 girls and 954 325 boys; mean [SD] age at first season entry, 12.6 [9.6] months) and 8680 CLD infant-seasons (3519 girls and 5161 boys; mean [SD] age at first season entry, 15.1 [9.1] months). Among term infants with siblings, the risk of hospitalization for RSV averaged across all covariate strata was 9.0 (95% CI, 8.4-9.6) per 1000 patient season-months at 1 month of age. The risk of hospitalization for RSV among preterm infants with CLD became similar to that of 1-month-old term infants at an age of 18.5 months (95% CI, 15.6-22.8). Conclusions and Relevance:The age threshold at which the risk of hospitalization for RSV among qualifying preterm infants with CLD approximates that of healthy term infants supports the current American Academy of Pediatrics practice guideline recommending RSV prophylaxis until a maximum of 24 months of age.
journal_name
JAMA Pediatrjournal_title
JAMA pediatricsauthors
Winterstein AG,Choi Y,Meissner HCdoi
10.1001/jamapediatrics.2017.3792subject
Has Abstractpub_date
2018-02-01 00:00:00pages
154-160issue
2eissn
2168-6203issn
2168-6211pii
2664530journal_volume
172pub_type
杂志文章相关文献
JAMA Pediatrics文献大全abstract:Importance:Enamel defects of developmental origin affect up to 38% of schoolchildren and is recognized as a global public health challenge. The impaired enamel formation results in pain owing to hypersensitivity, posteruptive breakdowns, rapid caries progression, and extractions in some cases. The etiology is unknown; ...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2019.2545
更新日期:2019-08-05 00:00:00
abstract:Importance:Pneumonia is the leading infectious killer of children. Rigorous evidence supporting antibiotic treatment of children with nonsevere fast-breathing pneumonia in low-resource African settings is lacking. Objective:To assess whether treatment with placebo for nonsevere fast-breathing pneumonia is substantivel...
journal_title:JAMA pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1001/jamapediatrics.2018.3407
更新日期:2019-01-01 00:00:00
abstract::OBJECTIVES To determine the effect of modifiable dietary intake variables (current vitamin D supplementation and daily cow's milk intake) on 25-hydroxyvitamin D level in early childhood and to evaluate the relationship between these modifiable dietary factors and other largely nonmodifiable determinants of vitamin D s...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/2013.jamapediatrics.226
更新日期:2013-03-01 00:00:00
abstract:Importance:Raising the price of cigarettes by increasing taxation has been associated with improved perinatal and child health outcomes. Transnational tobacco companies have sought to undermine tobacco tax policy by adopting pricing strategies that maintain the availability of budget cigarettes. Objective:To assess as...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2017.2536
更新日期:2017-11-01 00:00:00
abstract:IMPORTANCE:For the past 100 years, medicine in industrialized nations has become increasingly focused on specific medical interventions designed to improve the health of individual patients. Substantial evidence suggests that broader improvements in public health, nutrition, and economic well-being are more salient tha...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2013.1379
更新日期:2013-06-01 00:00:00
abstract:Importance:Cycled (intermittent) phototherapy (PT) might adequately control peak total serum bilirubin (TSB) level and avoid mortality associated with usual care (continuous PT) among extremely low-birth-weight (ELBW) infants (401-1000 g). Objective:To identify a cycled PT regimen that substantially reduces PT exposur...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2020.0559
更新日期:2020-07-01 00:00:00
abstract:Importance:Parent-based sexual health interventions have received considerable attention as one factor that can increase safer sexual behavior among youth; however, to our knowledge, the evidence linking parent-based interventions to youth sexual behaviors has not been empirically synthesized. Objective:To examine the...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2019.2324
更新日期:2019-07-29 00:00:00
abstract:IMPORTANCE:Obesity affects health in children and adolescents. Television viewing is an established risk factor for obesity in youth. No prospective study has assessed whether a bedroom television confers an additional risk for obesity in youth. OBJECTIVE:To assess the prospective association between the presence of a...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2013.3921
更新日期:2014-05-01 00:00:00
abstract:Importance:Retention in addiction treatment is associated with reduced mortality for individuals with opioid use disorder (OUD). Although clinical trials support use of OUD medications among youths (adolescents and young adults), data on timely receipt of buprenorphine hydrochloride, naltrexone hydrochloride, and metha...
journal_title:JAMA pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1001/jamapediatrics.2018.2143
更新日期:2018-11-01 00:00:00
abstract:IMPORTANCE:Histamine-2 receptor antagonists (H2RAs) are frequently used in the treatment of gastroesophageal reflux disease (GERD) in children; however, their efficacy and safety is questionable. OBJECTIVE:To systematically review the literature to assess the efficacy and safety of H2RAs in pediatric GERD. EVIDENCE R...
journal_title:JAMA pediatrics
pub_type: 杂志文章,评审
doi:10.1001/jamapediatrics.2014.1273
更新日期:2014-10-01 00:00:00
abstract:Importance:In several countries, 5 years after 13-valent pneumococcal conjugate vaccine (PCV13) implementation, serotype replacement has been reported for invasive pneumococcal disease, which raises concerns about the long-term outcome of PCV13 implementation. The long-term effect of vaccination on community-acquired p...
journal_title:JAMA pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1001/jamapediatrics.2018.5273
更新日期:2019-04-01 00:00:00
abstract:IMPORTANCE:In recent years, across the United States, many school districts have cut on-site delivery of health services by eliminating or reducing services provided by qualified school nurses. Providing cost-benefit information will help policy makers and decision makers better understand the value of school nursing s...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2013.5441
更新日期:2014-07-01 00:00:00
abstract:IMPORTANCE:Given the importance of developing healthy eating patterns during early childhood, policies to improve the elementary school food and beverage environments are critical. OBJECTIVE:To examine the association between district and state policy and/or law requirements regarding competitive food and beverages an...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2013.32
更新日期:2013-08-01 00:00:00
abstract:Importance:Sudden infant death syndrome remains the leading cause of death in infants aged 1 month to 1 year in the United States. Observations:While its exact cause is unknown, sudden infant death syndrome is believed to be multifactorial, ie, occurs in infants with underlying biological vulnerability who experience ...
journal_title:JAMA pediatrics
pub_type: 杂志文章,评审
doi:10.1001/jamapediatrics.2016.3345
更新日期:2017-02-01 00:00:00
abstract:Importance:Prenatal and neonatal cystic kidney diseases are a group of rare disorders manifesting as single, multiple unilateral, or bilateral cysts or with increased echogenicity of the renal cortex without macroscopic cysts. They may be accompanied by grossly enlarged kidneys, renal oligohydramnios, pulmonary hypopla...
journal_title:JAMA pediatrics
pub_type: 共识发展会议,杂志文章
doi:10.1001/jamapediatrics.2017.3938
更新日期:2018-01-01 00:00:00
abstract:IMPORTANCE:Behavioral change interventions have demonstrated short-term efficacy in reducing sexually transmitted infection (STI)/human immunodeficiency virus (HIV) risk behaviors; however, few have demonstrated long-term efficacy. OBJECTIVE:To evaluate the efficacy of a telephone counseling prevention maintenance int...
journal_title:JAMA pediatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1001/jamapediatrics.2014.1436
更新日期:2014-10-01 00:00:00
abstract:Importance:Caffeine citrate therapy for apnea of prematurity reduces the rates of bronchopulmonary dysplasia, severe retinopathy, and neurodevelopmental disability at 18 months and may improve motor function at 5 years. Objective:To evaluate whether neonatal caffeine therapy is associated with improved functional outc...
journal_title:JAMA pediatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1001/jamapediatrics.2017.0238
更新日期:2017-06-01 00:00:00
abstract:Importance:Fexofenadine hydrochloride is a frequently used drug for treatment of allergic conditions during pregnancy, but the fetal safety of fexofenadine use has not been well studied. Objective:To investigate the risk of adverse fetal outcomes associated with fexofenadine use during pregnancy. Design, Setting, and...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2020.1316
更新日期:2020-08-01 00:00:00
abstract:Importance:Genome-wide association studies have identified genetic loci influencing obesity risk in children. However, the importance of these loci in the associations with weight reduction through lifestyle interventions has not been investigated in large intervention trials. Objective:To evaluate the associations be...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2020.5142
更新日期:2021-01-01 00:00:00
abstract:Importance:Zika virus infection can be prenatally passed from a pregnant woman to her fetus. There is sufficient evidence to conclude that intrauterine Zika virus infection is a cause of microcephaly and serious brain anomalies, but the full spectrum of anomalies has not been delineated. To inform pediatric clinicians ...
journal_title:JAMA pediatrics
pub_type: 杂志文章,评审
doi:10.1001/jamapediatrics.2016.3982
更新日期:2017-03-01 00:00:00
abstract:Importance:This study was designed to determine whether a preventive intervention focused on enhancing supportive parenting could ameliorate the association between exposure to poverty and brain development in low socioeconomic status African American individuals from the rural South. Objective:To determine whether pa...
journal_title:JAMA pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1001/jamapediatrics.2016.2988
更新日期:2017-01-01 00:00:00
abstract:IMPORTANCE:Late-term gestation (defined as the 41st week of pregnancy) is associated with increased risk of perinatal health complications. It is not known to what extent late-term gestation is associated with long-term cognitive and physical outcomes. Information about long-term outcomes may influence physician and pa...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2016.0238
更新日期:2016-08-01 00:00:00
abstract:Importance:A total of 25.7 million children in the United States are classified as overweight or obese. Obesity is associated with deficits in executive function, which may contribute to poor dietary decision-making. Less is known about the associations between being overweight or obese and brain development. Objectiv...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2019.4708
更新日期:2020-02-01 00:00:00
abstract:IMPORTANCE:Community-based efforts to prevent adolescent problem behaviors are essential to promote public health and achieve collective impact community wide. OBJECTIVE To test whether the Communities That Care (CTC) prevention system reduced levels of risk and adolescent problem behaviors community wide 8 years after...
journal_title:JAMA pediatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1001/jamapediatrics.2013.4009
更新日期:2014-02-01 00:00:00
abstract:Importance:Sales of specialized formula for managing cow's milk allergy (CMA) have increased, triggering concern that attribution of common infant symptoms, such as crying, vomiting, and rashes, to CMA may be leading to overdiagnosis, which could undermine breastfeeding. Objective:To understand whether CMA guideline r...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2020.0153
更新日期:2020-06-01 00:00:00
abstract:IMPORTANCE:The American Academy of Pediatrics treatment recommendations for neonatal jaundice are based on age-specific total serum bilirubin (TSB) levels. In May 2012, Ortho Clinical Diagnostics adjusted the calibrator values for Vitros Chemistry Products BuBc Slides (Ortho Clinical Diagnostics), a widely used method ...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2015.4944
更新日期:2016-06-01 00:00:00
abstract:IMPORTANCE:Smaller cerebral volumes at hospital discharge in very preterm (VPT) infants are associated with poor neurobehavioral outcomes. Brain growth from the newborn period to middle childhood has not been explored because longitudinal data have been lacking. OBJECTIVES:To examine the pattern of growth of cerebral ...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2016.0781
更新日期:2016-08-01 00:00:00
abstract:Importance:Administration of corticosteroids to women at high risk for delivery in the late preterm period (34-36 weeks' gestation) improves short-term neonatal outcomes. The cost implications of this intervention are not known. Objective:To compare the cost-effectiveness of treatment with antenatal corticosteroids wi...
journal_title:JAMA pediatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1001/jamapediatrics.2019.0032
更新日期:2019-05-01 00:00:00
abstract::IMPORTANCE Excessive infant crying is common, distressing, but without proven effective prevention or management options. Probiotics may be a promising solution. OBJECTIVE To examine whether probiotics are effective in the prevention/management of crying ("colic") in infants 3 months or younger. DATA SOURCES A systema...
journal_title:JAMA pediatrics
pub_type: 杂志文章,meta分析,评审
doi:10.1001/jamapediatrics.2013.2572
更新日期:2013-12-01 00:00:00
abstract:Importance:Parents regularly express concern about long-term health outcomes for children who are born with an oral cleft. Objective:To assess whether oral clefts affect the health and ability to work of young adults. Design, Setting, and Participants:A population-based cohort study was conducted on all individuals b...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2016.1925
更新日期:2016-11-01 00:00:00