Abstract:
:Revision surgery of joint replacements is increasing and raises the demand for allograft bone since restoration of bone stock is crucial for longevity of implants. Proceedings of bone grafts influence the biological and mechanic properties differently. This study examines the effect of thermodisinfection on mechanic properties of cancellous bone. Bone cylinders from both femoral heads with length 45 mm were taken from twenty-three 6-8 months-old piglets, thermodisinfected at 82.5 °C according to bone bank guidelines and control remained native. The specimens were stored at -20 °C immediately and were put into 21 °C Ringer's solution for 3 h before testing. Shear and pressure modulus were tested since three point bending force was examined until destruction. Statistical analysis was done with non-parametric Wilcoxon, t test and SPSS since p < 0.05 was significant. Shear modulus was significantly reduced by thermodisinfection to 1.02 ± 0.31 GPa from 1.28 ± 0.68 GPa for unprocessed cancellous bone (p = 0.029) since thermodisinfection reduced pressure modulus not significantly from 6.30 ± 4.72 GPa for native specimens to 4.97 ± 2.23 GPa and maximum bending force was 270.03 ± 116.68 N for native and 228.80 ± 70.49 N for thermodisinfected cancellous bone. Shear and pressure modulus were reduced by thermodisinfection around 20 % and maximum bending force was impaired by about 15 % compared with native cancellous bone since only the reduction of shear modulus reached significance. The results suggest that thermodisinfection similarly affects different mechanic properties of cancellous bone and the reduction of mechanic properties should not relevantly impair clinical use of thermodisinfected cancellous bone.
journal_name
Cell Tissue Bankjournal_title
Cell and tissue bankingauthors
Fölsch C,Kellotat A,Rickert M,Ishaque B,Ahmed G,Pruss A,Jahnke Adoi
10.1007/s10561-016-9567-4subject
Has Abstractpub_date
2016-09-01 00:00:00pages
427-37issue
3eissn
1389-9333issn
1573-6814pii
10.1007/s10561-016-9567-4journal_volume
17pub_type
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journal_title:Cell and tissue banking
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journal_title:Cell and tissue banking
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journal_title:Cell and tissue banking
pub_type: 杂志文章,评审
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pub_type: 杂志文章
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journal_title:Cell and tissue banking
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pub_type: 杂志文章
doi:10.1007/s10561-005-0655-0
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journal_title:Cell and tissue banking
pub_type: 杂志文章
doi:10.1007/s10561-009-9124-5
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journal_title:Cell and tissue banking
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journal_title:Cell and tissue banking
pub_type: 杂志文章
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journal_title:Cell and tissue banking
pub_type: 临床试验,杂志文章
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