Abstract:
:The aim of this paper was to evaluate through histological analysis of the tissue reaction of deproteinized bovine bone matrix (DBBM) when inserted into the site of intramuscular ectopic sheep. In this study, 16 sheep received 3 groups and these were divided into 2 experimental times: Group 1-sham group, Group 2-particulate autogenous bone and Group 3-DBBM granules. All animals underwent surgical procedures for insertion of materials in an ectopic site (muscles of the lower back and after 3 and 6 months postoperatively, the samples were evaluated by histological analysis. The results indicated that the Sham group showed dense collagen fibers and thin, characterizing fibrosis at 3 and 6 months. In the autograft group there was a significant amount of collagen deposition and decreased inflammation at 6 months postoperatively. Group of DBBM, it was noted the presence of dense connective tissue and surrounding remaining particles was observed the formation of with osteoid characteristic tissue. The DBBM demonstrated biocompatibility, osteoconductivity and small osteogenesis capacity on ectopic site.
journal_name
Cell Tissue Bankjournal_title
Cell and tissue bankingauthors
Grossi JR,Bonacin R,Crivelaro VR,Giovanini AF,Zielak JC,Deliberador TMdoi
10.1007/s10561-016-9588-zsubject
Has Abstractpub_date
2016-12-01 00:00:00pages
689-697issue
4eissn
1389-9333issn
1573-6814pii
10.1007/s10561-016-9588-zjournal_volume
17pub_type
杂志文章abstract::Quality control and standardized preservation methods are essential in the field of transplantation. The International Organization for Standardization (ISO) has established a common set of manufacturing, trade and communications standards that are applicable worldwide and that provide the basis of a quality plan for ...
journal_title:Cell and tissue banking
pub_type: 杂志文章
doi:10.1023/A:1011576332362
更新日期:2001-01-01 00:00:00
abstract::Delivering the promise of personalised medicine is the challenge that the current generation of scientists face. The variations in human physiology and disease are considerable, and designing appropriate strategies to deliver what has been promised will require access to tissue from a large number of volunteers. The N...
journal_title:Cell and tissue banking
pub_type: 杂志文章
doi:10.1007/s10561-010-9212-6
更新日期:2011-02-01 00:00:00
abstract::Current regulatory requirements demand an in-depth understanding and validation of protocols used in tissue banking. The aim of this work was to characterize the quality of split thickness skin allografts cryopreserved or manufactured using highly concentrated solutions of glycerol (50, 85 or 98%), where tissue water ...
journal_title:Cell and tissue banking
pub_type: 杂志文章
doi:10.1007/s10561-018-9694-1
更新日期:2018-06-01 00:00:00
abstract::Despite a plethora of studies on overall attitudes related to organ donation in a health care setting, little is known as to whether or not medical students at various levels of undergraduate training have distinctive attitudes towards donation. The purpose of this study was to analyze attitudes of first- and sixth-ye...
journal_title:Cell and tissue banking
pub_type: 杂志文章
doi:10.1007/s10561-014-9491-4
更新日期:2015-09-01 00:00:00
abstract::Human sperm banking is an important procedure in the assisted reproductive technique centers. It entails sperm damage. The aim of this study was to investigate beneficial effect of Ceratonia siliqua (C. siliqua) supplement in freezing/thawing media on post thaw sperm parameters and sperm chromatin quality in normozoos...
journal_title:Cell and tissue banking
pub_type: 杂志文章
doi:10.1007/s10561-019-09779-2
更新日期:2019-09-01 00:00:00
abstract::The increased use of allograft tissue for musculoskeletal repair has brought more focus to the safety of allogenic tissue and the efficacy of various sterilization techniques. Gamma irradiation is an effective method for providing terminal sterilization to biological tissue, but it is also reported to have deleterious...
journal_title:Cell and tissue banking
pub_type: 杂志文章
doi:10.1007/s10561-008-9069-0
更新日期:2008-12-01 00:00:00
abstract::Defatting is an important procedure for the preparation of bone grafts because lipids in bone grafts strongly influence the osteointegration. Lipases have been widely used in different fields. However, study on the application to defatting process for bone grafts preparation has never been found so far. In this study,...
journal_title:Cell and tissue banking
pub_type: 杂志文章
doi:10.1007/s10561-013-9391-z
更新日期:2014-09-01 00:00:00
abstract::Cerebral ischemic injury as the main manifestation of stroke can occur in stroke patients (70-80%). Nowadays, the main therapeutic strategy used for ischemic brain injury treatment aims to achieve reperfusion, neuroprotection, and neurorecovery. Also, angiogenesis as a therapeutic approach maybe represents a promising...
journal_title:Cell and tissue banking
pub_type: 杂志文章,评审
doi:10.1007/s10561-020-09885-6
更新日期:2020-11-24 00:00:00
abstract::Brain donations are imperative for research; understanding possible barriers to entry is required to improve brain donation rates. While a few surveys have studied attitudes towards brain banking in patients with neurodegenerative disorders, none have surveyed patients with chronic neurological disorders but without n...
journal_title:Cell and tissue banking
pub_type: 杂志文章
doi:10.1007/s10561-020-09819-2
更新日期:2020-06-01 00:00:00
abstract::The purpose of the present research was: 1. To investigate the opportunity of application of allogen osteoplastic materials such as Lioplast, received in Samara Tissue Bank of Samara State Medical University. 2. To work out a new technique of producing lyophilized allogen osteoplastic materials, such as Lioplast, with...
journal_title:Cell and tissue banking
pub_type: 杂志文章
doi:10.1007/s10561-004-7254-3
更新日期:2005-01-01 00:00:00
abstract::Appropriate animal models are critical to conduct translational studies of human disorders without variables that can confound clinical studies. Such analytic methods as patch-clamp electrophysiological and voltammetric recordings of neurons in brain slices require living brain tissue. In order to obtain viable tissue...
journal_title:Cell and tissue banking
pub_type: 杂志文章
doi:10.1007/s10561-013-9380-2
更新日期:2014-03-01 00:00:00
abstract::This study was conducted to compare the quantitative and qualitative indices of the donated corneas maintained in either Optisol-GS or Eusol-C storage media. In an ante-grade single blind study, two corneas from each donor with a death to preservation time of less than 30 h and with a minimum of "an apparent good corn...
journal_title:Cell and tissue banking
pub_type: 杂志文章
doi:10.1007/s10561-014-9466-5
更新日期:2015-06-01 00:00:00
abstract::As banked human tissues are not widely available, the development of new non-destructive and contactless techniques to evaluate the quality of allografts before distribution for transplantation is very important. Also, tissues will be processed accordingly to standard procedures and to minimize disease transmission mo...
journal_title:Cell and tissue banking
pub_type: 杂志文章
doi:10.1007/s10561-013-9389-6
更新日期:2014-09-01 00:00:00
abstract::A thick gingival biotype is a requisite for good periodontal health. It has important role in resisting trauma and subsequent gingival recession. The gingival thickness is a significant predictor of clinical outcome of periodontal surgeries. Various surgical procedures are used to increase the gingival thickness. The ...
journal_title:Cell and tissue banking
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10561-015-9524-7
更新日期:2016-03-01 00:00:00
abstract::To compare the quality of the repair tissue in three-dimensional co-culture of human chondrocytes implanted in an in vivo model. Six cadaveric and five live human donors were included. Osteochondral biopsies from the donor knees were harvested for chondrocyte isolation. Fifty percent of cadaveric chondrocytes were exp...
journal_title:Cell and tissue banking
pub_type: 杂志文章
doi:10.1007/s10561-017-9635-4
更新日期:2017-09-01 00:00:00
abstract::Rheumatoid arthritis (RA) is the most common degenerative arthritic cartilage and represents a disease where the prospect of stem cell therapy offers considerable hope. Currently, bone marrow (BM) represents the major source of mesenchymal stem cells (MSCs) for cell therapy. In the pathology of RA, the pro-inflammator...
journal_title:Cell and tissue banking
pub_type: 杂志文章
doi:10.1007/s10561-012-9354-9
更新日期:2013-12-01 00:00:00
abstract::This study was conducted to evaluate the effect of combined cysteine and glutathione in soy lecithin-based semen extender on post-thawed ram sperm quality. A total of 28 ejaculates were collected twice a week (from four rams) during breeding season. In each replicate, semen samples (n = 4, one ejaculate for each ram) ...
journal_title:Cell and tissue banking
pub_type: 杂志文章
doi:10.1007/s10561-014-9488-z
更新日期:2015-09-01 00:00:00
abstract::Cellular stress to ejaculated spermatozoa such as cryopreservation is known to induce caspase-derived, apoptotic signaling. Therefore, the proenzymes and active forms of caspases 1, 3, 8 and 9 were examined by western blot technique in unfrozen and frozen human spermatozoa of infertility patients and of healthy donors...
journal_title:Cell and tissue banking
pub_type: 杂志文章
doi:10.1007/s10561-005-0276-7
更新日期:2006-01-01 00:00:00
abstract::Although therapeutics derived from biological sources have been subjected to regulatory oversight for some time, the products used in transplantation procedures have historically been exempt from this oversight. These products have been viewed as being part of medical practice rather than as the result of mainstream p...
journal_title:Cell and tissue banking
pub_type: 杂志文章,评审
doi:10.1007/s10561-006-9012-1
更新日期:2006-01-01 00:00:00
abstract::In Malaysia, tissue banking activities began in Universiti Sains Malaysia (USM) Tissue Bank in early 1990s. Since then a few other bone banks have been set up in other government hospitals and institutions. However, these banks are not governed by the national authority. In addition there is no requirement set by the ...
journal_title:Cell and tissue banking
pub_type: 杂志文章
doi:10.1007/s10561-010-9188-2
更新日期:2010-11-01 00:00:00
abstract::Mesenchymal stem cells (MSCs) have vast potential in cell therapy, and are experimentally used in the clinic. Therefore, it is critical to find a serum- and xeno-free cryopreservation method. The aim of this study was to compare two serum- and xeno-free cryoprotectants for MSCs. Adipose tissue MSCs (Ad-MSCs) and bone ...
journal_title:Cell and tissue banking
pub_type: 杂志文章
doi:10.1007/s10561-014-9463-8
更新日期:2015-06-01 00:00:00
abstract::Cryopreservation increases the rate of apoptotic spermatozoa with decreased capability to fertilise oocytes. In order to optimise the fertilisation rates, especially in assisted reproduction the use of apoptotic sperms should be avoided. Early events of apoptosis in cryopreserved spermatozoa are not detectable by conv...
journal_title:Cell and tissue banking
pub_type: 杂志文章
doi:10.1023/A:1020188913551
更新日期:2001-01-01 00:00:00
abstract::To vitrify human amniotic membrane specimens so that the maximum of epithelial cells survives in order to develop a procedure for the eventual vitrification of posterior corneal lamellae without using cryoprotective agents. To assess different methods of tissue sample preparation preceding vitrification. In group 1, t...
journal_title:Cell and tissue banking
pub_type: 杂志文章
doi:10.1007/s10561-013-9388-7
更新日期:2014-03-01 00:00:00
abstract::Decellularised tissue allografts have been used in reconstructive surgical applications and transplantation for many years. Some of the current methods of sterilisation have a detrimental effect on the tissue graft structure and function. The anti-microbial activity of cupric ions and hydrogen peroxide (H2O2) are well...
journal_title:Cell and tissue banking
pub_type: 杂志文章
doi:10.1007/s10561-017-9660-3
更新日期:2017-12-01 00:00:00
abstract::Autologous chondrocyte implantation has been shown to be a promising method for treatment of deep articular cartilage defects. The hyaline cartilage formed by implanted autologous chondrocytes has biomechanical properties similar to those of natural articular cartilage. Between June 2006 and September 2008 we performe...
journal_title:Cell and tissue banking
pub_type: 杂志文章
doi:10.1007/s10561-009-9163-y
更新日期:2010-05-01 00:00:00
abstract::We evaluated the value of the 'alternative slices mirror image method' used in prostate tissue banking in terms of predicting the sampling of cancerous tissue while preserving the pathological prognostic information. The concordance of diagnosis between banked sections and their mirror image paraffin- sections was stu...
journal_title:Cell and tissue banking
pub_type: 杂志文章
doi:10.1007/s10561-011-9284-y
更新日期:2012-12-01 00:00:00
abstract::We report two cases of severe endophthalmitis, which were caused by Serratia marcescens, and developed in the immediate postoperative period in two recipients of corneal grafts from the same donor. The cause of the donor's death was massive CVA. He had been on mechanical ventilation for 12 days before he died, and had...
journal_title:Cell and tissue banking
pub_type: 杂志文章
doi:10.1023/A:1021839711471
更新日期:2002-01-01 00:00:00
abstract::Although allografts for anterior cruciate ligament (ACL) replacement have shown advantages compared to autografts, their use is limited due to the risk of disease transmission and the limitations of available sterilization methods. Gamma sterilization has shown detrimental effects on graft properties at the high doses...
journal_title:Cell and tissue banking
pub_type: 杂志文章
doi:10.1007/s10561-011-9289-6
更新日期:2012-08-01 00:00:00
abstract::Demineralized freeze-dried bone allograft (DFDBA) has been used extensively in periodontal therapy. Questions have been raised however, about the osteogenic potential of the variety of grafts available. In India the cost factor is another important consideration. The aim of this study therefore was to evaluate the cli...
journal_title:Cell and tissue banking
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10561-014-9481-6
更新日期:2015-09-01 00:00:00
abstract::The aim of this study is to set up a standardized and reproducible method to determine the potency (= stem cell content) of human conjunctival cell cultures by means of immunofluorescence-based analyses. This will help the development of new Advanced Therapy Medicinal Products (ATMPs) to use in future cell therapy cli...
journal_title:Cell and tissue banking
pub_type: 杂志文章
doi:10.1007/s10561-020-09874-9
更新日期:2020-10-13 00:00:00