Maternal predictors and quality of umbilical cord blood units.

Abstract:

:The aim of the study was to determine the relationship between the maternal age at delivery and selected properties of the cord blood stem cells. The study included 50 pregnant women aged between 18 and 38 years in which spontaneous labors or elective cesarean sections were performed. Umbilical cord blood was collected immediately after the women were delivered of newborns. The samples were analyzed in the Polish Stem Cells Bank in Warsaw. The highest mean WBC level (p < 0.05) was observed in the umbilical blood collected from patients aged 35 years and more. Similarly, the highest mean cell viability was observed in the umbilical cord blood collected from patients aged 35 and more. There were no statistically significant correlations between the CD34+ cells count and mean cell viability in the umbilical cord blood and the maternal age. With the significance level at p < 0.001, the females after spontaneous labor revealed a visibly higher WBC level than patients after a cesarean section. The higher mean WBC concentration (24.95 thousand/μl) was observed in the umbilical cord blood of patients aged 35 and more after spontaneous labors. In the same group, the umbilical cord blood was also characterized by the highest mean cell viability (98.72%). The number of nucleated cells in the umbilical cord blood collected in the perinatal period increases together with the maternal age. In the course of physiological spontaneous labors, the collected umbilical cord blood has more nucleated cells as compared with elective caesarian sections.

journal_name

Cell Tissue Bank

journal_title

Cell and tissue banking

authors

Bielec-Berek B,Jastrzębska-Stojko Ż,Drosdzol-Cop A,Jendyk C,Boruczkowski D,Ołdak T,Nowak-Brzezińska A,Stojko R

doi

10.1007/s10561-017-9657-y

subject

Has Abstract

pub_date

2018-03-01 00:00:00

pages

69-75

issue

1

eissn

1389-9333

issn

1573-6814

pii

10.1007/s10561-017-9657-y

journal_volume

19

pub_type

杂志文章
  • Assessment of bioburden on human and animal tissues: Part 1--results of method development and validation studies.

    abstract::Recovered human and animal tissues are used extensively in surgery for wound repair and reconstruction. In preparation for the validation of chemical disinfection and radiation sterilization processes, studies were performed on the development and validation of quantitative bioburden recovery methods for human bone an...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章

    doi:10.1007/s10561-010-9238-9

    authors: Kowalski JB,Mosley GA,Merritt K,Osborne J

    更新日期:2012-03-01 00:00:00

  • Standardized method for the harvest of nonhuman primate tissue optimized for multiple modes of analyses.

    abstract::Appropriate animal models are critical to conduct translational studies of human disorders without variables that can confound clinical studies. Such analytic methods as patch-clamp electrophysiological and voltammetric recordings of neurons in brain slices require living brain tissue. In order to obtain viable tissue...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章

    doi:10.1007/s10561-013-9380-2

    authors: Davenport AT,Grant KA,Szeliga KT,Friedman DP,Daunais JB

    更新日期:2014-03-01 00:00:00

  • Effects of continuous passage on immunomodulatory properties of human adipose-derived stem cells.

    abstract::Human adipose-derived stem cells (hADSCs) have the ability to influence immune response, and hence are key cell sources for tissue repair and regeneration. In this study we explored the effect of continuous passage on the immunomodulatory properties of hADSCs to provide some advises for large-scale production of hADSC...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章

    doi:10.1007/s10561-014-9451-z

    authors: Wang X,Liu C,Li S,Xu Y,Chen P,Liu Y,Ding Q,Wahapu W,Hong B,Yang M

    更新日期:2015-03-01 00:00:00

  • The effect of cryopreservation on DNA methylation patterns of the chromosome 15q11-q13 region in human spermatozoa.

    abstract::Human sperm cryopreservation is a common technique which is used in assisted reproductive technologies. Despite the existence of evidence supporting the production of ROS and DNA fragmentation during sperm cryopreservation, there is little and equivocal information about the cryopreservation effects on methylation of ...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章

    doi:10.1007/s10561-020-09828-1

    authors: Khosravizadeh Z,Hassanzadeh G,Tavakkoly Bazzaz J,Alizadeh F,Totonchi M,Salehi E,Khodamoradi K,Khanehzad M,Hosseini SR,Abolhassani F

    更新日期:2020-09-01 00:00:00

  • Tissue banking for research: connecting the disconnected.

    abstract::Delivering the promise of personalised medicine is the challenge that the current generation of scientists face. The variations in human physiology and disease are considerable, and designing appropriate strategies to deliver what has been promised will require access to tissue from a large number of volunteers. The N...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章

    doi:10.1007/s10561-010-9212-6

    authors: Thomas G

    更新日期:2011-02-01 00:00:00

  • Isolation of human dermis derived mesenchymal stem cells using explants culture method: expansion and phenotypical characterization.

    abstract::Recent studies have reported that stem cells can be isolated from a wide range of tissues including bone marrow, fatty tissue, adipose tissue and placenta. Moreover, several studies also suggest that skin dermis could serve as a source of stem cells, but are of unclear phenotype. Therefore, we isolated and investigate...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章

    doi:10.1007/s10561-014-9471-8

    authors: Park JR,Kim E,Yang J,Lee H,Hong SH,Woo HM,Park SM,Na S,Yang SR

    更新日期:2015-06-01 00:00:00

  • Amnion-derived mesenchymal stromal cells show a mesenchymal-epithelial phenotype in culture.

    abstract::The amnionic membrane is a rich source of multipotent mesenchymal stromal cells (hAMSC), which are readily available and show a potential use in regenerative medicine and tissue engineering. Before these cells can be applied clinically, careful characterization is necessary, especially as primary cells are known to ch...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章

    doi:10.1007/s10561-013-9415-8

    authors: König J,Lang I,Siwetz M,Fröhlich J,Huppertz B

    更新日期:2014-06-01 00:00:00

  • Potential of 5-azacytidine induction decidual stromal cells from maternal human term placenta towards cardiomyocyte-like cells in serum-free medium.

    abstract::Decidual stromal cells (DSCs) from maternal term placenta represent a potential source of cells for the treatment of cardiovascular and graft-versus-host diseases. However, it is not clear whether DSCs could be induced towards cardiomyocyte-like differentiation. We chose the placentas which should bred male new-baby. ...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章

    doi:10.1007/s10561-015-9493-x

    authors: Chen G,Yue A,Ruan Z,Yin Y,Wang R,Ren Y,Zhu L

    更新日期:2015-09-01 00:00:00

  • ISBT 128: a global information standard.

    abstract::ISBT 128 is the global standard for the identification, labeling and information transfer of human blood, cell, tissue and organ products across international borders and disparate health care systems. The system has been designed and perfected over almost two decades to ensure accuracy, safety and efficiency for the ...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章

    doi:10.1007/s10561-010-9196-2

    authors: Distler P

    更新日期:2010-11-01 00:00:00

  • Bulgarian Bone Marrow Donors Registry--past and future directions.

    abstract::Recently Bulgarian Bone Marrow Donors Registry (BBMDR) has been established and since August 2005 it has been a member of Bone Marrow Donors Worldwide. Currently the number of healthy donors included in the BBMDR is relatively low. All donors included in the BBMDR are typed for HLA-A, -B, -DRB loci. Phylogenetic analy...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章

    doi:10.1007/s10561-007-9046-z

    authors: Zlatev A,Ivanova M,Michailova S,Mihaylova A,Naumova E

    更新日期:2008-12-01 00:00:00

  • Cryopreservation procedure does not modify human carotid homografts mechanical properties: an isobaric and dynamic analysis.

    abstract::The viscoelastic and inertial properties of the arterial wall are responsible for the arterial functional role in the cardiovascular system. Cryopreservation is widely used to preserve blood vessels for vascular reconstruction but it is controversially suspected to affect the dynamic behaviour of these allografts. The...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章

    doi:10.1007/s10561-005-0655-0

    authors: Bia D,Pessana F,Armentano R,Pérez H,Graf S,Zócalo Y,Saldías M,Perez N,Alvarez O,Silva W,Machin D,Sueta P,Ferrin S,Acosta M,Alvarez I

    更新日期:2006-01-01 00:00:00

  • Co-culture of dedifferentiated and primary human chondrocytes obtained from cadaveric donor enhance the histological quality of repair tissue: an in-vivo animal study.

    abstract::To compare the quality of the repair tissue in three-dimensional co-culture of human chondrocytes implanted in an in vivo model. Six cadaveric and five live human donors were included. Osteochondral biopsies from the donor knees were harvested for chondrocyte isolation. Fifty percent of cadaveric chondrocytes were exp...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章

    doi:10.1007/s10561-017-9635-4

    authors: Olivos-Meza A,Velasquillo Martínez C,Olivos Díaz B,Landa-Solís C,Brittberg M,Pichardo Bahena R,Ortega Sanchez C,Martínez V,Alvarez Lara E,Ibarra-Ponce de León JC

    更新日期:2017-09-01 00:00:00

  • Patient attitudes towards brain donation across both neurodegenerative and non-neurodegenerative neurological disorders.

    abstract::Brain donations are imperative for research; understanding possible barriers to entry is required to improve brain donation rates. While a few surveys have studied attitudes towards brain banking in patients with neurodegenerative disorders, none have surveyed patients with chronic neurological disorders but without n...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章

    doi:10.1007/s10561-020-09819-2

    authors: Chan RJW,Seah S,Foo JYJ,Yong ACW,Chia NSY,Agustin SJU,Neo SXM,Tay KY,Au WL,Tan LCS,Ng ASL

    更新日期:2020-06-01 00:00:00

  • The efficacy and sterilisation of human decellularised dermal allografts with combinations of cupric ions and hydrogen peroxide.

    abstract::Decellularised tissue allografts have been used in reconstructive surgical applications and transplantation for many years. Some of the current methods of sterilisation have a detrimental effect on the tissue graft structure and function. The anti-microbial activity of cupric ions and hydrogen peroxide (H2O2) are well...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章

    doi:10.1007/s10561-017-9660-3

    authors: Leow-Dyke SF,Rooney P,Kearney JN

    更新日期:2017-12-01 00:00:00

  • Activation of caspases in human spermatozoa during cryopreservation--an immunoblot study.

    abstract::Cellular stress to ejaculated spermatozoa such as cryopreservation is known to induce caspase-derived, apoptotic signaling. Therefore, the proenzymes and active forms of caspases 1, 3, 8 and 9 were examined by western blot technique in unfrozen and frozen human spermatozoa of infertility patients and of healthy donors...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章

    doi:10.1007/s10561-005-0276-7

    authors: Wündrich K,Paasch U,Leicht M,Glander HJ

    更新日期:2006-01-01 00:00:00

  • Implementation of a Quality Plan (ISO 9002) In a Regional Tissue Bank.

    abstract::Quality control and standardized preservation methods are essential in the field of transplantation. The International Organization for Standardization (ISO) has established a common set of manufacturing, trade and communications standards that are applicable worldwide and that provide the basis of a quality plan for ...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章

    doi:10.1023/A:1011576332362

    authors: Villalba R,Eisman M,Fornés G,Mesa A,De Torres P,Ariza MJ,Gutierrez Guzmán A,Gómez Villagrán JL

    更新日期:2001-01-01 00:00:00

  • A banking strategy toward customized therapy in breast cancer.

    abstract::In breast cancer, various clinical parameters are assessed to define clinical stage and thus obtain a more accurate prognosis. However, banks of tumor tissues are an important source of material for studies of risk of recurrence and of features governing clinical outcome in breast cancer. Although the heterogeneous ch...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章

    doi:10.1007/s10561-009-9124-5

    authors: Nardone A,Cavaliere C,Corvigno S,Limite G,De Placido S,Veneziani BM

    更新日期:2009-11-01 00:00:00

  • Regeneration of sciatic nerves by transplanted microvesicles of human neural stem cells derived from embryonic stem cells.

    abstract::Injured nerves cannot regenerate on their own, and a lack of engraftable human nerves has been a major obstacle in cell-based therapies for regenerating damaged nerves. A monolayer culture approach to obtain adherent neural stem cells from human embryonic stem cells (hESC-NSCs) was established, and the greatest number...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章

    doi:10.1007/s10561-020-09816-5

    authors: Chen X,Ye K,Yu J,Gao J,Zhang L,Ji X,Chen T,Wang H,Dai Y,Tang B,Xu H,Sun X,Hu J

    更新日期:2020-06-01 00:00:00

  • The role of IL-6 in bone marrow (BM)-derived mesenchymal stem cells (MSCs) proliferation and chondrogenesis.

    abstract::Rheumatoid arthritis (RA) is the most common degenerative arthritic cartilage and represents a disease where the prospect of stem cell therapy offers considerable hope. Currently, bone marrow (BM) represents the major source of mesenchymal stem cells (MSCs) for cell therapy. In the pathology of RA, the pro-inflammator...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章

    doi:10.1007/s10561-012-9354-9

    authors: Wei H,Shen G,Deng X,Lou D,Sun B,Wu H,Long L,Ding T,Zhao J

    更新日期:2013-12-01 00:00:00

  • Negative effect of combined cysteine and glutathione in soy lecithin-based extender on post-thawed ram spermatozoa.

    abstract::This study was conducted to evaluate the effect of combined cysteine and glutathione in soy lecithin-based semen extender on post-thawed ram sperm quality. A total of 28 ejaculates were collected twice a week (from four rams) during breeding season. In each replicate, semen samples (n = 4, one ejaculate for each ram) ...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章

    doi:10.1007/s10561-014-9488-z

    authors: Zhandi M,Sharafi M

    更新日期:2015-09-01 00:00:00

  • Analysis of impact on tissue activity during COVID-19 outbreak: a survey of 8 banks in Spain.

    abstract::On March 19 World Health Organization declare the pandemic situation by outbreak coronavirus disease 2019 in the world. The pressure on the health care system has been very high in several countries. Spanish National Transplant Organization (ONT) have made many efforts in maintaining transplantation activity. Although...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s10561-020-09853-0

    authors: Villalba R,Santos S,Martinez MJ,Díaz M,Pevida M,Cemborain A,Casares C,Mirabet V

    更新日期:2020-12-01 00:00:00

  • Mesenchymal stem cells for chronic wounds therapy.

    abstract::Wound healing is a complex process that involves interaction of soluble mediators, extracellular matrix and infiltrating blood cells. Chronic and non-healing skin defects contribute significantly to morbidity and mortality of many patients. Recently, despite the current medical progress, the chronic and non-healing wo...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章,评审

    doi:10.1007/s10561-014-9440-2

    authors: Zahorec P,Koller J,Danisovic L,Bohac M

    更新日期:2015-03-01 00:00:00

  • Effects of very rapid versus vapor phase freezing on human sperm parameters.

    abstract::The aim of the present study was to compare the effects of two freezing methods, vapor phase and very rapid freezing, with and without cryoprotectant on semen parameters in men with normal semen criteria. Cryopreservation was done on semen samples from 31 men by two methods of vapor phase freezing and very rapid freez...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章

    doi:10.1007/s10561-012-9351-z

    authors: Darvishnia H,Lakpour N,Lahijani MS,Heidari-Vala H,Akhondi MA,Zeraati H,Sadeghi MR

    更新日期:2013-12-01 00:00:00

  • Biocompatibility Studies of a New Biosynthetic Dermal Substitute Based on Collagen/Hyaluronan Conjugate.

    abstract::The use of glycosaminoglycans (GAGs) as the second macromolecular component with collagen for the membrane preparation is based on the idea to create a biodegradable scaffold for new tissue. A hybrid collagen/hyaluronan membrane with specific bubble macrostructure was designed to serve as a synthetic dermal substitute...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章

    doi:10.1023/a:1010181925236

    authors: Koller J,Bakos D,Sadlonová I I

    更新日期:2000-01-01 00:00:00

  • A new standardized immunofluorescence method for potency quantification (SMPQ) of human conjunctival cell cultures.

    abstract::The aim of this study is to set up a standardized and reproducible method to determine the potency (= stem cell content) of human conjunctival cell cultures by means of immunofluorescence-based analyses. This will help the development of new Advanced Therapy Medicinal Products (ATMPs) to use in future cell therapy cli...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章

    doi:10.1007/s10561-020-09874-9

    authors: Bertolin M,Breda C,Ferrari S,Lamon M,Ponzin D,Ferrari B,Barbaro V

    更新日期:2020-10-13 00:00:00

  • When do tissues and cells become products? Regulatory oversight of emerging biological therapies.

    abstract::Although therapeutics derived from biological sources have been subjected to regulatory oversight for some time, the products used in transplantation procedures have historically been exempt from this oversight. These products have been viewed as being part of medical practice rather than as the result of mainstream p...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章,评审

    doi:10.1007/s10561-006-9012-1

    authors: Farrugia A

    更新日期:2006-01-01 00:00:00

  • Comparing the use of glycerol preserved and cryopreserved allogenic skin for the treatment of severe burns: differences in clinical outcomes and in vitro tissue viability.

    abstract::Cryopreserved (CryoPA) and Glycerol-preserved (GPA) skin allografts are commonly used in the treatment of severe burn injuries. However, comparable data on their differences in clinical outcome is scarce. This retrospective review aims to study the effect of allograft viability on clinical outcomes. The records of 48 ...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章

    doi:10.1007/s10561-011-9254-4

    authors: Kua EH,Goh CQ,Ting Y,Chua A,Song C

    更新日期:2012-06-01 00:00:00

  • Comparative evaluation of bioburden and sterility of indigenously prepared bone allograft with and without gentamicin.

    abstract::During bone allograft processing, despite stringent donor screening and use of aseptic techniques, microbial invasion may occur due to the porous nature of the graft and cause potentially fatal infections. The aim of the present study was to prepare bone allograft with and without gentamicin and to compare bioburden a...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章

    doi:10.1007/s10561-019-09763-w

    authors: Makker K,Lamba AK,Faraz F,Tandon S,Sheikh Ab Hamid S,Aggarwal K,Chowdhri K

    更新日期:2019-06-01 00:00:00

  • A method of isolating viable chondrocytes with proliferative capacity from cryopreserved human articular cartilage.

    abstract::This study aimed to optimise methods of cryopreserving human articular cartilage (AC) tissue for the isolation of late chondrocytes. Human AC specimens from osteoarthritis patients who had undergone total knee replacement were used to optimise the chondrocyte isolation process and the choice of cryoprotective agent (C...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章

    doi:10.1007/s10561-012-9328-y

    authors: Xia Z,Duan X,Murray D,Triffitt JT,Price AJ

    更新日期:2013-06-01 00:00:00

  • Dimethyl sulfoxide toxicity kinetics in intact articular cartilage.

    abstract::Osteochondral defects can degenerate into osteoarthritis and currently there are no good treatment alternatives available to most Orthopaedic surgeons. Osteochondral allografting can restore damaged joint surfaces but its clinical use is limited by poor access to high quality tissue. Vitrification of osteochondral tis...

    journal_title:Cell and tissue banking

    pub_type: 杂志文章

    doi:10.1007/s10561-006-9023-y

    authors: Elmoazzen HY,Poovadan A,Law GK,Elliott JA,McGann LE,Jomha NM

    更新日期:2007-01-01 00:00:00