Selective Expression of Osteopontin in ALS-resistant Motor Neurons is a Critical Determinant of Late Phase Neurodegeneration Mediated by Matrix Metalloproteinase-9.

abstract：:A Chemical absorption-bioelectrochemical reduction (CABER) system is based on Chemical absorption-biological reduction (CABR) system, which aims at NO removal and has been studied in many of our previous works. In this paper, we applied polypyrrole (PPy) on the electrode of bioelectrochemical reactor (BER) of CABER sy...

journal_title：Scientific reports

authors： Guo T,Zhang C,Zhao J,Ma C,Li S,Li W

更新日期：2019-09-10 00:00:00

abstract：:Classical swine fever (CSF) is a notifiable, highly contagious viral disease of swine which results in severe welfare and economic consequences in affected countries. To improve preparedness, it is critical to have some understanding of how CSF would spread should it be introduced. Based on the data recorded during th...

journal_title：Scientific reports

authors： Porphyre T,Correia-Gomes C,Chase-Topping ME,Gamado K,Auty HK,Hutchinson I,Reeves A,Gunn GJ,Woolhouse ME

更新日期：2017-02-22 00:00:00

abstract：:Size shifts may be a by-product of alterations in life history traits driven by natural selection. Although this approach has been proposed for islands, it has not yet been explored in continental faunas. The trends towards size decrease experienced by some hipparionins constitute a good case study for the application...

journal_title：Scientific reports

authors： Orlandi-Oliveras G,Nacarino-Meneses C,Koufos GD,Köhler M

更新日期：2018-11-21 00:00:00

abstract：:Plasmonics has established itself as a branch of physics which promises to revolutionize data processing, improve photovoltaics, and increase sensitivity of bio-detection. A widespread use of plasmonic devices is notably hindered by high losses and the absence of stable and inexpensive metal films suitable for plasmon...

journal_title：Scientific reports

authors： Kravets VG,Jalil R,Kim YJ,Ansell D,Aznakayeva DE,Thackray B,Britnell L,Belle BD,Withers F,Radko IP,Han Z,Bozhevolnyi SI,Novoselov KS,Geim AK,Grigorenko AN

更新日期：2014-07-01 00:00:00

abstract：:Chemical chaperones including arginine and its derivatives are widely used by biochemists working on the design of agents, which are able to efficiently suppress protein aggregation. To elucidate the mechanisms of anti-aggregation activity of chemical chaperones, methods based on registration of the increment in light...

journal_title：Scientific reports

authors： Borzova VA,Markossian KA,Kleymenov SY,Kurganov BI

更新日期：2017-06-21 00:00:00

abstract：:Nanotechnology can improve the performance of dental polymers. The objective of this study was to modify the surfaces of nanoparticles with silanes and proteins, characterize nanoparticles' agglomeration levels and interfaces between nanoparticles and the polymeric matrix. Undoped (n-TiO2), nitrogen-doped (N_TiO2) and...

journal_title：Scientific reports

authors： Esteban Florez FL,Trofimov AA,Ievlev A,Qian S,Rondinone AJ,Khajotia SS

更新日期：2020-06-17 00:00:00

abstract：:Ergothioneine (ERG), a unique thiol compound, is suggested to function as an antioxidant and cytoprotectant. Despite several recent attempts to produce ERG using various organisms, its yield was still very low and the costs remained high. Since the level of ERG produced depends strictly on the availability of three di...

journal_title：Scientific reports

authors： Tanaka N,Kawano Y,Satoh Y,Dairi T,Ohtsu I

更新日期：2019-02-13 00:00:00

abstract：:Immune responses against gene therapy products limit its therapeutic efficacy and present a safety risk. Identification of agents that blunt immune reactions may aid in developing novel immunomodulatory therapies. Fingolimod (FTY720) is an FDA approved immunomodulatory drug for treating multiple sclerosis that inhibit...

journal_title：Scientific reports

authors： Baer A,Colon-Moran W,Bhattarai N

更新日期：2018-07-19 00:00:00

abstract：:Colistin remains one of the few antibiotics effective against multi-drug resistant (MDR) hospital pathogens, such as Klebsiella pneumoniae. Yet resistance to this last-line drug is rapidly increasing. Characterized mechanisms of colR in K. pneumoniae are largely due to chromosomal mutations in two-component regulators...

journal_title：Scientific reports

authors： Cain AK,Boinett CJ,Barquist L,Dordel J,Fookes M,Mayho M,Ellington MJ,Goulding D,Pickard D,Wick RR,Holt KE,Parkhill J,Thomson NR

更新日期：2018-06-29 00:00:00

abstract：:With countless biological details emerging from cancer experiments, there is a growing need for minimal mathematical models which simultaneously advance our understanding of single tumors and metastasis, provide patient-personalized predictions, whilst avoiding excessive hard-to-measure input parameters which complica...

journal_title：Scientific reports

authors： Choe SC,Zhao G,Zhao Z,Rosenblatt JD,Cho HM,Shin SU,Johnson NF

更新日期：2011-01-01 00:00:00

abstract：:Owing to the diversity of pulse-wave morphology, pulse-based diagnosis is difficult, especially pulse-wave-pattern classification (PWPC). A powerful method for PWPC is a convolutional neural network (CNN). It outperforms conventional methods in pattern classification due to extracting informative abstraction and featu...

journal_title：Scientific reports

authors： Li G,Watanabe K,Anzai H,Song X,Qiao A,Ohta M

更新日期：2019-10-17 00:00:00

abstract：:Facial mimicry has been suggested to be a behavioral index for emotional empathy. The present study is the first to investigate the link between facial muscle activity and empathy for pain by facial electromyographic (EMG) recording while observers watched videos depicting real-life painful events. Three types of visu...

journal_title：Scientific reports

authors： Sun YB,Wang YZ,Wang JY,Luo F

更新日期：2015-12-09 00:00:00

abstract：:Keratoconus is a common degenerative corneal disease that can lead to significant visual morbidity, and both genetic and environmental factors have been implicated in its pathogenesis. We compared the transcriptome of keratoconus and control epithelium using RNA-Seq. Epithelial tissues were obtained prior to surgery f...

journal_title：Scientific reports

authors： You J,Corley SM,Wen L,Hodge C,Höllhumer R,Madigan MC,Wilkins MR,Sutton G

更新日期：2018-01-10 00:00:00

abstract：:Glassy carbon electrode (GCE) was modified with metal oxides (MO = Fe3O4, ZnO) nanoparticles doped phthalocyanine (Pc) and functionalized MWCNTs, and the electrocatalytic properties were studied. Successful synthesis of the metal oxide nanoparticles and the MO/Pc/MWCNT composite were confirmed using FTIR, Raman and SE...

journal_title：Scientific reports

authors： Mphuthi NG,Adekunle AS,Ebenso EE

更新日期：2016-06-01 00:00:00

abstract：:Although most papillary thyroid carcinomas (PTCs) have a good prognosis, a small but certain fraction shows aggressive behavior. Therefore, a novel and well-performing molecular marker is needed. In the present study, we assessed the impact of the combination of the TERT promoter/BRAF mutations and Ki-67 labeling inde...

journal_title：Scientific reports

authors： Matsuse M,Yabuta T,Saenko V,Hirokawa M,Nishihara E,Suzuki K,Yamashita S,Miyauchi A,Mitsutake N

更新日期：2017-02-02 00:00:00

abstract：:Our previous studies indicated that combination of Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and PPARγ ligand Troglitazone (TZD), can induce significant apoptosis in various TRAIL-resistant prostate and hepatocellular carcinoma (HCC) cells. These also suggested serine/threonine kinase AMP-activat...

journal_title：Scientific reports

authors： Ke R,Vishnoi K,Viswakarma N,Santha S,Das S,Rana A,Rana B

更新日期：2018-04-03 00:00:00

abstract：:Large-scale anthropogenic disturbances can have direct and indirect effects on marine communities, with direct effects often taking the form of widespread injury or mortality and indirect effects manifesting as changes in food web structure. Here, we report a time series that captures both direct and indirect effects ...

journal_title：Scientific reports

authors： Lewis JP,Tarnecki JH,Garner SB,Chagaris DD,Patterson WF 3rd

更新日期：2020-04-09 00:00:00

abstract：:Patients with schizophrenia have a higher risk for cardiovascular disease (CVD) than the general population. Research has suggested that autonomic imbalance is a common pathway to increased morbidity and mortality for CVD. Heart rate variability (HRV) analysis is a non-invasive method that assesses autonomic imbalance...

journal_title：Scientific reports

authors： Wang J,Liu YS,Zhu WX,Zhang FQ,Zhou ZH

更新日期：2014-12-09 00:00:00

abstract：:We report on the synthesis and electrical properties of nine new alkylated silane self-assembled monolayers (SAMs) - (EtO)3Si(CH2)nN = CHPhX where n = 3 or 11 and X = 4-CF3, 3,5-CF3, 3-F-4-CF3, 4-F, or 2,3,4,5,6-F, and explore their rectification behavior in relation to their molecular structure. The electrical proper...

journal_title：Scientific reports

authors： Lamport ZA,Broadnax AD,Harrison D,Barth KJ,Mendenhall L,Hamilton CT,Guthold M,Thonhauser T,Welker ME,Jurchescu OD

更新日期：2016-11-29 00:00:00

abstract：:Networks in nature are often formed within a spatial domain in a dynamical manner, gaining links and nodes as they develop over time. Motivated by the growth and development of neuronal networks, we propose a class of spatially-based growing network models and investigate the resulting statistical network properties a...

journal_title：Scientific reports

authors： Zitin A,Gorowara A,Squires S,Herrera M,Antonsen TM,Girvan M,Ott E

更新日期：2014-11-14 00:00:00

abstract：:We report on a novel electrically tunable hybrid graphene-gold Fano resonator. The proposed metamaterial consists of a square graphene patch and a square gold frame. The destructive interference between the narrow- and broadband dipolar surface plasmons, which are induced respectively on the surfaces of the graphene p...

journal_title：Scientific reports

authors： Amin M,Farhat M,Baǧcı H

更新日期：2013-01-01 00:00:00

abstract：:Quantum bits (qubits) are at the heart of quantum information processing schemes. Currently, solid-state qubits, and in particular the superconducting ones, seem to satisfy the requirements for being the building blocks of viable quantum computers, since they exhibit relatively long coherence times, extremely low diss...

journal_title：Scientific reports

authors： Ivić Z,Lazarides N,Tsironis GP

更新日期：2016-07-12 00:00:00

abstract：:In this decade coherent X-ray diffraction imaging has been demonstrated to reveal internal structures of whole biological cells and organelles. However, the spatial resolution is limited to several tens of nanometers due to the poor scattering power of biological samples. The challenge is to recover correct phase info...

journal_title：Scientific reports

authors： Takayama Y,Maki-Yonekura S,Oroguchi T,Nakasako M,Yonekura K

更新日期：2015-01-28 00:00:00

abstract：:Coherent B2-ordered NiAl-type precipitates have been used to reinforce solid-solution body-centered-cubic iron for high-temperature application in fossil-energy power plants. In this study, we investigate the stability of nano-sized precipitates in a NiAl-strengthened ferritic alloy at 700-950 °C using ultra-small ang...

journal_title：Scientific reports

authors： Sun Z,Song G,Ilavsky J,Ghosh G,Liaw PK

更新日期：2015-11-05 00:00:00

abstract：:The organismic unit of heterocyst-forming cyanobacteria is a filament of communicating cells connected by septal junctions, proteinaceous structures bridging the cytoplasms of contiguous cells. This distinct bacterial organization is preserved during cell division. In Anabaena, deletion of the zipN gene could not be s...

journal_title：Scientific reports

authors： Camargo S,Picossi S,Corrales-Guerrero L,Valladares A,Arévalo S,Herrero A

更新日期：2019-02-26 00:00:00

abstract：:Mitochondrial disorders are among the most prevalent inborn errors of metabolism but largely lack treatments and have poor outcomes. High-fat, low-carbohydrate ketogenic diets (KDs) have shown beneficial effects in mouse models of mitochondrial myopathies, with induction of mitochondrial biogenesis as the suggested ma...

journal_title：Scientific reports

authors： Purhonen J,Rajendran J,Mörgelin M,Uusi-Rauva K,Katayama S,Krjutskov K,Einarsdottir E,Velagapudi V,Kere J,Jauhiainen M,Fellman V,Kallijärvi J

更新日期：2017-04-19 00:00:00

abstract：:In this study, we propose a novel sensitive solid-based immunosensor developed on a plasmonic nanopaper platform for the detection of Escherichia coli (E. coli) bacteria. This plasmonic nanopaper that comprises of carboxylated bacterial cellulose (CBC) impregnated with gold nanoparticles (AuNP-CBC), employed as a quen...

journal_title：Scientific reports

authors： Heli B,Ajji A

更新日期：2020-09-01 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Prywer J,Torzewska A

更新日期：2020-01-27 00:00:00

abstract：:Common features of immune-metabolic and inflammatory diseases such as metabolic syndrome, diabetes, obesity and cardiovascular diseases are an altered gut microbiota composition and a systemic pro-inflammatory state. We demonstrate that active immunization against the outer membrane protein of bacteria present in the ...

journal_title：Scientific reports

authors： Saita D,Ferrarese R,Foglieni C,Esposito A,Canu T,Perani L,Ceresola ER,Visconti L,Burioni R,Clementi M,Canducci F

更新日期：2016-07-07 00:00:00

abstract：:Current saliva testing methods rely on cutting edge yet expensive techniques for the detection and analysis of genetic material, proteins and biomarkers for clinical use. However, these techniques are limited in scope and often cannot be used with complex food materials. We propose an efficient ex-vivo tool for evalua...

journal_title：Scientific reports

authors： Dinu V,Liu C,Ali J,Ayed C,Gershkovich P,Adams GG,Harding SE,Fisk ID

更新日期：2018-09-06 00:00:00