Abstract:
:Extinction-resistant fear is considered to be a central feature of pathological anxiety. Here we sought to determine if individual differences in Intolerance of Uncertainty (IU), a potential risk factor for anxiety disorders, underlies compromised fear extinction. We tested this hypothesis by recording electrodermal activity in 38 healthy participants during fear acquisition and extinction. We assessed the temporality of fear extinction, by examining early and late extinction learning. During early extinction, low IU was associated with larger skin conductance responses to learned threat vs. safety cues, whereas high IU was associated with skin conductance responding to both threat and safety cues, but no cue discrimination. During late extinction, low IU showed no difference in skin conductance between learned threat and safety cues, whilst high IU predicted continued fear expression to learned threat, indexed by larger skin conductance to threat vs. safety cues. These findings suggest a critical role of uncertainty-based mechanisms in the maintenance of learned fear.
journal_name
Biol Psycholjournal_title
Biological psychologyauthors
Morriss J,Christakou A,van Reekum CMdoi
10.1016/j.biopsycho.2016.05.001subject
Has Abstractpub_date
2016-12-01 00:00:00pages
187-193issue
Pt Beissn
0301-0511issn
1873-6246pii
S0301-0511(16)30175-2journal_volume
121pub_type
杂志文章abstract::Integrating the implicit-affect-primes-effort model (Gendolla, 2012, 2015) with the principles of motivational intensity theory (Brehm & Self, 1989) we investigated if the effort mobilization deficit observed in people exposed to fear primes (vs. anger primes) in a difficult short-term memory task could be compensated...
journal_title:Biological psychology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.biopsycho.2016.03.014
更新日期:2016-05-01 00:00:00
abstract::Elevated cortisol is recognized as a transient response to stress, and is also found among patients with major depressive disorder. Abnormally high levels of thyroxin are associated with nervousness and irritability, while very low levels are associated with lethargy. Therefore it is reasonable to ask if variations in...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/0301-0511(94)90007-8
更新日期:1994-07-01 00:00:00
abstract::Neural processing of emotional pictures is often indexed by two electrocortical responses: the early posterior negativity (EPN) and the late positive potential (LPP). Because emotional pictures vary in nonemotional features (e.g., composition, human content, and spatial frequency), researchers often match pictures on ...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2010.11.001
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Studies on depression have found that childhood abuse (CA) is associated with a persistent sensitization of the hypothalamic-pituitary-adrenal (HPA)-axis to stress in adulthood. So far, it is unknown whether this HPA-axis sensitization is specific to depression, or whether this is a more general outcome asso...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2009.09.006
更新日期:2010-01-01 00:00:00
abstract::Event-related potentials (ERPs) were recorded from 25 adolescents in a modification of the odd-ball paradigm. On alternate blocks subjects were required to detect either a missing stimulus or a change in pitch, each of which occurred 17% of the time and was embedded in a series of background tone pips (66% occurrence)...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/0301-0511(84)90028-0
更新日期:1984-02-01 00:00:00
abstract::We investigated the temperamental traits high-intensity pleasure (temperamental activation) and shyness (temperamental inhibition) in relation to autonomic function as measured by heart rate (HR), respiratory sinus arrhythmia (RSA), and baroreflex sensitivity (BRS) in 938 10-13-year-old preadolescents from a populatio...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2009.02.002
更新日期:2009-04-01 00:00:00
abstract::This study examined the effects of attachment styles on physiological responses during a perspective-taking task. Sixty-eight participants were selected according to attachment styles. Physiological responses were assessed using skin conductance responses (SCRs) in the three attachment groups (secure, insecure-anxious...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2020.107908
更新日期:2020-07-01 00:00:00
abstract::There are documented physiological differences between single and coupled individuals during the "honeymoon period" of nascent romantic relationships. One such difference is in autonomic reactivity, specifically heart rate variability (HRV) reactivity. This finding had previously been interpreted as evidence of a stre...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2017.07.004
更新日期:2017-09-01 00:00:00
abstract::Previous event-related potential (ERP) studies have identified the specific electrophysiological markers of advance preparation in cued task-switching paradigms. However, it is not yet completely clear whether there is a single task-independent preparatory mechanism for task-switching or whether preparation for a swit...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2015.06.011
更新日期:2015-09-01 00:00:00
abstract::College students learned a set of facts relating fictitious people and their occupations (e.g. 'Matthew is a lawyer'). Event-related brain potentials (ERPs) were recorded while they subsequently viewed a series of such statements presented in segments (e.g. 'Matthew/is a/dentist'). ERPs to occupations completing state...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/0301-0511(85)90008-0
更新日期:1985-09-01 00:00:00
abstract::The object of this study was to explore the relevance of an amplitude threshold for defining alpha in biofeedback studies. One of the lowest thresholds used in earlier studies (1.5 microV) was selected and the EEG base level of 94 subjects measured. Due to the importance of reinforcement rate in biofeedback, results w...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/0301-0511(80)90021-6
更新日期:1980-08-01 00:00:00
abstract::Thirty-six participants (18 female, 18 male) viewed affective pictures to investigate the coupling between emotional reactions and motivated behavior. Framed within the biphasic theory of emotion, the three systems approach was employed by collecting measures of subjective report, expressive physiology, and motivated ...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2003.07.005
更新日期:2004-03-01 00:00:00
abstract::We examined the relationship between unemployment and heart rate variability (HRV) in a region of high unemployment in the Czech Republic. The study involved 21 involuntarily unemployed and 21 employed men and women aged 30-49 years, matched on number of potentially confounding factors, including age, gender, type of ...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2012.07.002
更新日期:2012-10-01 00:00:00
abstract::Recent studies of the nasal cycle and forced uni-nostril breathing have demonstrated that integrated EEG amplitudes are greater over the hemisphere contralateral to the dominant (less congested) or unblocked nostril. Two experiments were designed to determine if asymmetries in nasal airflow, occurring naturally as a r...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/0301-0511(86)90077-3
更新日期:1986-10-01 00:00:00
abstract::High cardiac vagal control (as measured by respiratory sinus arrhythmia; RSA) is associated with lower depression. Recent theories argue that people's responsiveness to social resources is a key mechanism in this association. This argument implies two hypotheses: first, high RSA should be related to decreased depressi...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2013.01.004
更新日期:2013-04-01 00:00:00
abstract::Men outperform women in mental rotation by about one standard deviation. Prenatal exposure to testosterone has been suggested as one cause. In animals it has been shown that a female fetus located between two male ones is exposed to higher levels of testosterone. It is still unclear whether intra-uterine hormone trans...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2010.11.002
更新日期:2011-01-01 00:00:00
abstract::We used the startle eye blink paradigm to investigate the processes underlying physiological responding to concealed information. Autonomic responding was measured together with eye blink responses to startle probes presented during mock crime and control pictures. Based upon 'orienting theory', greater startle modula...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2007.06.001
更新日期:2007-09-01 00:00:00
abstract::Post-traumatic stress disorder (PTSD) is characterized by avoidance, emotional numbing, increased arousal and hypervigilance for threat following a trauma. Thirty-three veterans (19 with PTSD, 14 without PTSD) who had experienced combat trauma while on deployment in Iraq and/or Afghanistan completed an emotional faces...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2013.08.009
更新日期:2013-10-01 00:00:00
abstract::Although the scientific community appears to know a lot about MMN, about its neural generators and the computational processes that underlie its generation, do we have sufficient knowledge to understand what causes the reduction of MMN amplitude in schizophrenia? Here we attempt to integrate the evidence presented in ...
journal_title:Biological psychology
pub_type: 杂志文章,评审
doi:10.1016/j.biopsycho.2016.01.011
更新日期:2016-04-01 00:00:00
abstract::Some experimental data demonstrate the existence of at least two different P300s distinguished by latency, topography and functional significance. These positive waves are preceded by a negative component which has been labelled N200. The purpose of this study was to analyze the modifications of these negative and pos...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/0301-0511(81)90036-3
更新日期:1981-12-01 00:00:00
abstract::While the personality trait of extraversion has been linked to enhanced reward sensitivity and its putative neural correlates, little is known about whether extraverts' neural circuits are particularly sensitive to social rewards, given their preference for social engagement and social interactions. Using event-relate...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2013.02.010
更新日期:2013-04-01 00:00:00
abstract::We compared individual differences in the ERP associated with incorrect responses in a discrimination task with other ERP components associated with attentional control and stimulus discrimination (N2, P3, CNV). Trials with errors that are detected by the subject normally produce a negativity (N(E)) immediately follow...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/s0301-0511(01)00080-1
更新日期:2001-06-01 00:00:00
abstract::In this study we explored the potential for capturing the behavioral dynamics observed in real-world tasks from concurrent measures of EEG. In doing so, we sought to develop models of behavior that would enable the identification of common cross-participant and cross-task EEG features. To accomplish this we had partic...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2015.12.009
更新日期:2016-02-01 00:00:00
abstract::This event-related potential (ERP) study investigated neural correlates of cognitive reappraisal during the exposure to food cues. Thirty-three healthy, normal-weight women viewed images of high-caloric food and non-food items after an overnight fast. The participants were instructed to either passively look at the pi...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2013.09.006
更新日期:2013-12-01 00:00:00
abstract::Both the Reward Positivity (RewP) and the novelty N2 component appear within the same spatio-temporal window. This signal overlap impedes the assessment of the RewP evoked by complex novel rewards like affective or motivational imagery. Here we conducted a series of experiments which successfully isolated signals of r...
journal_title:Biological psychology
pub_type: 临床试验,杂志文章
doi:10.1016/j.biopsycho.2020.107841
更新日期:2020-03-01 00:00:00
abstract::Older people sometimes show a bias toward the processing of positive information. In this study, we used an event-related potential approach to examine whether such a positivity bias is also present during feedback processing in older adults. Our results suggest that a fast initial monitoring process, as reflected in ...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2013.07.006
更新日期:2013-10-01 00:00:00
abstract::Until recently, sleep and hibernation were not usually considered to be closely related states (e.g. Dement, 1967). However, two current lines of research point toward a system of relations between caloric intake, thermogenesis, metabolic rate and adiposity in the regulation of the energy balance of warm-blooded anima...
journal_title:Biological psychology
pub_type: 杂志文章,评审
doi:10.1016/0301-0511(84)90045-0
更新日期:1984-12-01 00:00:00
abstract::The purpose was to reexamine cognitive performance and cortisol levels of initial clinical burnout patients, non-clinical burnout individuals, and healthy controls. After 1.5-years of the initial measurement, clinical burnout patients showed a reduction of burnout symptoms and general physical and psychological compla...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2016.02.009
更新日期:2016-05-01 00:00:00
abstract::We investigated whether chronic job stress, i.e., effort-reward imbalance (ERI) and overcommitment is associated with cellular immunity among 190 male and 157 female white-collar daytime employees (mean age 38; range 22-69 years). Participants provided a blood sample for the measurement of circulating immune (natural ...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2011.08.012
更新日期:2011-12-01 00:00:00
abstract::The purpose of the research reported here was to examine a number of issues relating to the nature of selective attention effects on auditory event-related potentials (ERPs), namely, to determine the relative contribution of N1 and slow wave (SW) to the early and late components of Nd respectively, where Nd is defined...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/0301-0511(90)90141-i
更新日期:1990-06-01 00:00:00