Effort-reward imbalance, overcommitment, and cellular immune measures among white-collar employees.

Abstract:

:We investigated whether chronic job stress, i.e., effort-reward imbalance (ERI) and overcommitment is associated with cellular immunity among 190 male and 157 female white-collar daytime employees (mean age 38; range 22-69 years). Participants provided a blood sample for the measurement of circulating immune (natural killer (NK), B, and T) cell counts and NK cell cytotoxicity (NKCC) and completed a questionnaire survey during April to June 2002. Stepwise multiple linear regression analyses revealed that NK cells were associated with effort (β=-.230; p=.013), reward (β=.169; p=.047), and ERI (β=-.182; p=.047) scores but not with overcommitment in men; reward score was positively associated with NKCC (β=.167; p=.049) and inversely associated with B cells (β=-.181; p=.030). No significant associations were found in women. Although the picture remains less clear in women, our findings suggest a potential immunological pathway linking adverse working conditions and stress-related disorders in men.

journal_name

Biol Psychol

journal_title

Biological psychology

authors

Nakata A,Takahashi M,Irie M

doi

10.1016/j.biopsycho.2011.08.012

subject

Has Abstract

pub_date

2011-12-01 00:00:00

pages

270-9

issue

2-3

eissn

0301-0511

issn

1873-6246

pii

S0301-0511(11)00201-8

journal_volume

88

pub_type

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