Abstract：
:Although the scientific community appears to know a lot about MMN, about its neural generators and the computational processes that underlie its generation, do we have sufficient knowledge to understand what causes the reduction of MMN amplitude in schizophrenia? Here we attempt to integrate the evidence presented in this series of papers for the special issue on MMN in schizophrenia together with evidence from other new relevant research and ask--what have we learnt? While MMN research was the purview for decades of psychophysiologists interested in event-related potentials derived from scalp recorded EEG, it is now part of mainstream neuroscience research attracting the interest of basic auditory neuroscientists, neurobiologists and computational modellers. The confluence of these developments together with increasing clinical research has certainly advanced our understanding of the causes of reduced MMN in schizophrenia as this integrative review attempts to demonstrate--but much remains to be learnt. Future advances will rely on the application of multiple methodologies and approaches in order to arrive at better understanding of the neurobiology of MMN and implications for schizophrenia.
journal_name
Biol Psycholjournal_title
Biological psychologyauthors
Michie PT,Malmierca MS,Harms L,Todd Jdoi
10.1016/j.biopsycho.2016.01.011subject
Has Abstractpub_date
2016-04-01 00:00:00pages
90-7eissn
0301-0511issn
1873-6246pii
S0301-0511(16)30021-7journal_volume
116pub_type
杂志文章,评审abstract：:We compared individual differences in the ERP associated with incorrect responses in a discrimination task with other ERP components associated with attentional control and stimulus discrimination (N2, P3, CNV). Trials with errors that are detected by the subject normally produce a negativity (N(E)) immediately follow...
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pub_type： 杂志文章
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pub_type： 杂志文章,随机对照试验
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pub_type： 杂志文章
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journal_title：Biological psychology
pub_type： 杂志文章
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更新日期：2013-10-01 00:00:00
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journal_title：Biological psychology
pub_type： 杂志文章
doi：10.1016/j.biopsycho.2013.11.010
更新日期：2014-02-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2008-03-01 00:00:00
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pub_type： 杂志文章
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更新日期：2011-03-01 00:00:00
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journal_title：Biological psychology
pub_type： 杂志文章
doi：10.1016/j.biopsycho.2004.08.003
更新日期：2005-07-01 00:00:00
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更新日期：2011-12-01 00:00:00
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journal_title：Biological psychology
pub_type： 杂志文章
doi：10.1016/j.biopsycho.2010.05.003
更新日期：2010-09-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.biopsycho.2016.06.012
更新日期：2016-09-01 00:00:00
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journal_title：Biological psychology
pub_type： 杂志文章
doi：10.1016/j.biopsycho.2005.11.002
更新日期：2006-05-01 00:00:00
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更新日期：2017-02-01 00:00:00
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更新日期：2018-05-01 00:00:00
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pub_type： 杂志文章
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更新日期：2014-02-01 00:00:00
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更新日期：1997-03-21 00:00:00
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pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：1996-01-05 00:00:00
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pub_type： 杂志文章
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journal_title：Biological psychology
pub_type： 杂志文章
doi：10.1016/j.biopsycho.2008.01.011
更新日期：2008-05-01 00:00:00
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journal_title：Biological psychology
pub_type： 杂志文章
doi：10.1016/j.biopsycho.2009.09.006
更新日期：2010-01-01 00:00:00
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journal_title：Biological psychology
pub_type： 杂志文章
doi：10.1016/j.biopsycho.2016.10.005
更新日期：2017-02-01 00:00:00
