Premeal insulin decreases arterial stiffness in children with type 1 diabetes.

abstract：BACKGROUND AND OBJECTIVE:Incidence rates of type 1 diabetes have long been on the rise across the globe, however, there is emerging evidence that the rate of rise may be slowing. The objective of this study was to describe trends in the incidence and prevalence of type 1 diabetes in a sample of Canadian children and yo...

journal_title：Pediatric diabetes

authors： Fox DA,Islam N,Sutherland J,Reimer K,Amed S

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:To evaluate diabetes knowledge and skills (DKS) in adolescents (>10 year) with type 1 diabetes (T1D) and their parents, and its effect on glycemic control. METHODS:A ready-to-use program and a standardized questionnaire comprising 50 true-false questions based on this program, were elaborated by a National C...

journal_title：Pediatric diabetes

authors： Martin D,Elie C,Dossier C,Godot C,Gagnayre R,Choleau C,Cahané M,Robert JJ,AJD Study Group.

更新日期：2017-11-01 00:00:00

abstract：:Although the factors responsible for the recent increase in the prevalence of diabetes worldwide are not entirely known, the morbidity associated with this disease results in substantial health and economic burden on society. Epigenetic modifications, including DNA methylation have been identified as one mechanism by ...

journal_title：Pediatric diabetes

authors： Bansal A,Pinney SE

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:Proinsulin is a marker of beta-cell distress and dysfunction in type 2 diabetes and transplanted islets. Proinsulin levels are elevated in patients newly diagnosed with type 1 diabetes. Our aim was to assess the relationship between proinsulin, insulin dose-adjusted haemoglobin A1c (IDAA1C), glucagon-like pep...

journal_title：Pediatric diabetes

authors： Kaas A,Andersen ML,Fredheim S,Hougaard P,Buschard K,Petersen JS,de Beaufort C,Robertson KJ,Hansen L,Mortensen HB,Nielsen LB,Hvidoere Study Group on childhood diabetes.

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVE:To describe vitamin D levels and prevalence of vitamin D sufficiency, insufficiency and deficiency in a large, ethnically/racially diverse population of youth with type 1 diabetes (T1D) and type 2 diabetes (T2D) in comparison to national data and examine the associations between clinical/demographic factors a...

journal_title：Pediatric diabetes

authors： Wood JR,Connor CG,Cheng P,Ruedy KJ,Tamborlane WV,Klingensmith G,Schatz D,Gregg B,Cengiz E,Willi S,Bacha F,Beck RW,Pediatric Diabetes Consortium.

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:Avoiding complications is paramount in diabetes management, but little is known about how, when, and what diabetes professionals disclose to parents and youths about this topic. RESEARCH DESIGN AND METHOD:Pediatric diabetes experts (n = 534) were surveyed about their practices and attitudes regarding informi...

journal_title：Pediatric diabetes

authors： Lochrie AS,Wysocki T,Burnett J,Buckloh LM,Antal H

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:To explore the outcomes of monthly video consultations for children with diabetes. METHODS:The Virtual Outpatient Diabetes Clinic for Children and Youth (VIDIKI) was a 6-month multicenter controlled clinical trial followed by an extension phase. The 240 participants (1-16 years), all using a CGM, were quasi-...

journal_title：Pediatric diabetes

authors： von Sengbusch S,Eisemann N,Mueller-Godeffroy E,Lange K,Doerdelmann J,Erdem A,Menrath I,Bokelmann J,Krasmann M,Kaczmarczyk P,Bertram B,Hiort O,Katalinic A,Frielitz FS

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:It is unknown whether measurement site of visceral adipose tissue (VAT) influences the relationship between VAT and associated health risk in youth and if so, whether ethnic differences exist in this relationship. We examined the influence of the measurement site of VAT on the relationships between VAT and me...

journal_title：Pediatric diabetes

authors： Lee S,Kuk JL,Kim Y,Arslanian SA

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:The current study examined how a comprehensive set of variables from multiple domains, including at the adolescent and family level, were predictive of glycemic control in adolescents with type 1 diabetes (T1D). METHODS:Participants included 100 adolescents with T1D ages 10-16 yrs and their parents. Particip...

journal_title：Pediatric diabetes

authors： Agarwal S,Jawad AF,Miller VA

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Alterations in glucose metabolism that lead to the development of metabolic and cardiovascular disease may begin already in childhood. OBJECTIVE:This study aims to generate pediatric age and sex-specific reference values for fasting concentrations of glucose, hemoglobin A1c (HbA1c), insulin, C-peptide, and ...

journal_title：Pediatric diabetes

authors： Frithioff-Bøjsøe C,Lund MAV,Kloppenborg JT,Nielsen TTH,Fonvig CE,Lausten-Thomsen U,Hedley PL,Hansen T,Pedersen OB,Christiansen M,Baker JL,Hansen T,Holm JC

更新日期：2019-08-01 00:00:00

abstract：:Persistent 'IgE-mediated' insulin allergy (type 1 allergy) (1), unresponsive to changes in insulin type or the use of antihistamines, necessitates desensitization. A number of case reports (2-7) and recent reviews (8, 9) have demonstrated that desensitization can be achieved with continuous subcutaneous insulin infusi...

journal_title：Pediatric diabetes

authors： Neville KA,Verge CF,Wainstein BK,Woodhead HJ,Ziegler JB,Walker JL

更新日期：2008-08-01 00:00:00

abstract：AIMS:The cardiovascular risk factor profile of a child as well as the development of body weight are influenced by genetic and childhood factors. Circulating insulin concentrations reflect the metabolic cardiovascular risk and may trigger weight gain. We aimed at identifying parental and childhood factors which may inf...

journal_title：Pediatric diabetes

authors： Brandt S,Moß A,Lennerz B,Koenig W,Weyermann M,Rothenbacher D,Brenner H,Wabitsch M

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:The aim of the study was to search for mutations in the NEUROD1 and IPF-1 genes in patients with clinical characteristics of maturity-onset diabetes of the young (MODY) but with no mutations in the HNF-4A (MODY1), GCK (MODY2) and TCF1 (MODY3) genes. METHODS:We studied 30 unrelated Czech probands with a clin...

journal_title：Pediatric diabetes

authors： Gonsorcíková L,Průhová S,Cinek O,Ek J,Pelikánová T,Jørgensen T,Eiberg H,Pedersen O,Hansen T,Lebl J

更新日期：2008-08-01 00:00:00

abstract：:Diabetic ketoacidosis (DKA) is one of the most common causes of morbidity and mortality in new onset type 1 diabetes mellitus (T1DM). Children have a higher rate of neurological complications from DKA when compared to adults. The differential for sudden focal neurological deterioration in the setting of DKA is cerebra...

journal_title：Pediatric diabetes

authors： Finn BP,Power C,McSweeney N,Breen D,Wyse G,O'Connell SM

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:While insulin resistance (IR) is associated with specific metabolite signatures in adults, there have been few truly longitudinal studies in healthy children, either to confirm which abnormalities are present, or to determine whether they precede or result from IR. Therefore, we investigated the association ...

journal_title：Pediatric diabetes

authors： Hosking J,Pinkney J,Jeffery A,Cominetti O,Da Silva L,Collino S,Kussmann M,Hager J,Martin FP

更新日期：2019-11-01 00:00:00

abstract：UNLABELLED:Previous studies have shown that vigorous aerobic training programs for obese children result in minimal weight changes, and concluded that they may not be beneficial. Weight change alone may not detect important beneficial changes in body composition associated with vigorous training in these children. Fift...

journal_title：Pediatric diabetes

authors： DeStefano RA,Caprio S,Fahey JT,Tamborlane WV,Goldberg B

更新日期：2000-06-01 00:00:00

abstract：:Glucokinase gene (GCK) mutations comprise approximately 10% of cases of maturity-onset diabetes of the young (MODY). Over 800 different mutations in GCK have been reported in the Human Gene Mutation Database, the vast majority of which result in MODY type 2. The missense mutation p.Leu122Val is listed in that database...

journal_title：Pediatric diabetes

authors： Hunter JD,Staton H,Constantacos C,Walsh ET,Crudo DF

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:High serum uric acid (SUA) levels are present in patients with metabolic syndrome (MetS), when the latter is associated with endothelial dysfunction, inflammation, and hypertension. This increase in SUA levels may have a key role in cardiovascular diseases. OBJECTIVE:We aim to quantify the differences in in...

journal_title：Pediatric diabetes

authors： Valle M,Martos R,Cañete MD,Valle R,van Donkelaar EL,Bermudo F,Cañete R

更新日期：2015-09-01 00:00:00

abstract：AIM:The aim of this study was to compare genetic (HLA-DQ) and immune markers in a large population of type 1 diabetic (T1D) children and adolescents residing in the same environment, but of different ethnic origin: European Caucasians (EC), Moghrabin Caucasians (MC), Black Africans (BA) and of Mixed Origin (MO). METHO...

journal_title：Pediatric diabetes

authors： Stoupa A,Dorchy H

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:There is marked variation in diabetes outcomes for children and adolescents across the UK. We used modelling techniques to examine the independent contributions of deprivation, ethnicity, insulin pump use, and health service use on HbA1c trajectories across adolescence. METHODS:Prospective data from a large...

journal_title：Pediatric diabetes

authors： Viner RM,White B,Amin R,Peters C,Khanolkar A,Christie D,Hindmarsh PC

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:Despite increased diabetes device use, few adolescents with type 1 diabetes (T1D) meet glycemic targets. We examine associations between utilization of insulin pumps and continuous glucose monitoring (CGM) and glycemic control. RESEARCH DESIGN AND METHODS:This prospective cohort study included 80 youths (10-...

journal_title：Pediatric diabetes

authors： Faulds ER,Hoffman RP,Grey M,Tan A,Tubbs-Cooley H,Militello LK,Happ MB

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:Characterization of partial remission using the insulin dose-adjusted HbA1c (IDAA1c) ≤ 9 definition in a multiethnic Brazilian population of children and adolescents with type 1 diabetes (T1D), in addition with the determination of both Class II HLA genotype and autoantibodies. METHODS:We analyzed the preval...

journal_title：Pediatric diabetes

authors： Camilo DS,Pradella F,Paulino MF,Baracat ECE,Marini SH,Guerra G Jr,Pavin EJ,Parisi C,Longhini ALF,Marques SB,Guariento EG,Lieber SR,Macedo CF,Gama E Silva L,Farias AS,Santos LMB,Volpini WMG

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Pediatric diabetes clinics around the world rapidly adapted care in response to COVID-19. We explored provider perceptions of care delivery adaptations and challenges for providers and patients across nine international pediatric diabetes clinics. METHODS:Providers in a quality improvement collaborative com...

journal_title：Pediatric diabetes

authors： Cristello Sarteau A,Souris KJ,Wang J,Ramadan AA,Addala A,Bowlby D,Corathers S,Forsander G,King B,Law JR,Liu W,Malik F,Pihoker C,Seid M,Smart C,Sundberg F,Tandon N,Yao M,Headley T,Mayer-Davis E

更新日期：2021-01-19 00:00:00

abstract：OBJECTIVE:Patient-reported outcomes have received increased attention as treatment outcomes and indicators of wellbeing. A1c has been criticized as lacking patient-centered relevance because individuals are often unaware of their A1c, and studies also often fail to show a benefit of intensive control on quality of life...

journal_title：Pediatric diabetes

authors： Kane NS,Hoogendoorn CJ,Commissariat PV,Schulder TE,Gonzalez JS

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:Type 2 diabetes (T2D) in youth is recognized as a pediatric disease, but few reports describe the characteristics during diagnosis. We describe the clinical presentation of 503 youth with T2D. METHODS:The Pediatric Diabetes Consortium (PDC) T2D Clinic Registry enrolled T2D participants from eight pediatric d...

journal_title：Pediatric diabetes

authors： Klingensmith GJ,Connor CG,Ruedy KJ,Beck RW,Kollman C,Haro H,Wood JR,Lee JM,Willi SM,Cengiz E,Tamborlane WV,Pediatric Diabetes Consortium.

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:To compare the aerobic exercise capacity between normal adolescents and those with type 1 diabetes mellitus (T1DM). METHODS:An experimental group with 72 individuals diagnosed with T1DM aged 9--20, time from diagnosis 4.9 +/- 3.6 yr, without clinical cardiopulmonary disease or anemia and a control group (C) ...

journal_title：Pediatric diabetes

authors： Komatsu WR,Gabbay MA,Castro ML,Saraiva GL,Chacra AR,de Barros Neto TL,Dib SA

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to determine the influence of regular physical activity on ghrelin and IGF-1/IGFBP-3 levels during a diabetes camp. METHODS:Twenty-eight children and adolescents (14 boys; mean age 12.1 yr) with type 1 diabetes mellitus (T1DM, mean duration of diabetes 4.8 yr) attending a 2-wk diabe...

journal_title：Pediatric diabetes

authors： Huber J,Fröhlich-Reiterer EE,Sudi K,Suppan E,Weinhandl G,Jasser-Nitsche H,Aigner R,Borkenstein MH

更新日期：2010-09-01 00:00:00

abstract：:Although it is known that the incidence of type 1 diabetes mellitus (DM) in childhood is progressively increasing, it is less clear whether the presentation of newly diagnosed DM is changing. The aim of this study was to establish whether any biochemical or clinical presentation parameters have altered over time. A re...

journal_title：Pediatric diabetes

authors： Jackson W,Hofman PL,Robinson EM,Elliot RB,Pilcher CC,Cutfield WS

更新日期：2001-12-01 00:00:00

abstract：:A subgroup of diabetic patients presents with features typical of type 1 diabetes, but over months to years has variable insulin requirements and develops features of type 2 diabetes. This subgroup is referred to as atypical diabetes mellitus (ADM). Over a span of 50 yr, reports on disease epidemiology, clinical chara...

journal_title：Pediatric diabetes

authors： Egede LE,Willi SM

更新日期：2000-12-01 00:00:00

abstract：:Type 1 diabetes is often accompanied with acute hypoinsulinemia that may theoretically inhibit the conversion of essential fatty acids to their longer-chain metabolites. Previously, we found significant reduction in plasma arachidonic (C20:4n-6) and docosahexaenoic (C22:6n-3) acid values in a group of diabetic childre...

journal_title：Pediatric diabetes

authors： Szabó E,Marosvölgyi T,Kozári A,Erhardt E,Soltész G,Decsi T

更新日期：2009-05-01 00:00:00