Functional Genome Screening to Elucidate the Colistin Resistance Mechanism.

abstract：:Functional magnetic resonance imaging (fMRI) based on the blood oxygen level dependent (BOLD) contrast has gained a prominent position in neuroscience for imaging neuronal activity and studying effective brain connectivity under working state and functional connectivity at resting state. However, the fundamental quest...

journal_title：Scientific reports

authors： Cui M,Zhou Y,Wei B,Zhu XH,Zhu W,Sanders MA,Ugurbil K,Chen W

更新日期：2017-06-02 00:00:00

abstract：:Accurately establishing the state of large-scale quantum systems is an important tool in quantum information science; however, the large number of unknown parameters hinders the rapid characterisation of such states, and reconstruction procedures can become prohibitively time-consuming. Compressive sensing, a procedur...

journal_title：Scientific reports

authors： Tonolini F,Chan S,Agnew M,Lindsay A,Leach J

更新日期：2014-10-13 00:00:00

abstract：:Nucleotide-binding domain and leucine-rich-repeat-containing family member X1 (NLRX1), located in mitochondria, can recognize cytoplasmic pattern recognition receptors and is tightly related to reactive oxygen species (ROS) production, mitochondrial function, apoptosis and inflammation. The present study was designed ...

journal_title：Scientific reports

authors： Yin H,Sun G,Yang Q,Chen C,Qi Q,Wang H,Li J

更新日期：2017-03-13 00:00:00

abstract：:Viewing facial expressions often evokes facial responses in the observer. These spontaneous facial reactions (SFRs) are believed to play an important role for social interactions. However, their developmental trajectory and the underlying neurocognitive mechanisms are still little understood. In the current study, 4- ...

journal_title：Scientific reports

authors： Kaiser J,Crespo-Llado MM,Turati C,Geangu E

更新日期：2017-12-13 00:00:00

abstract：:Systemic lipopolysaccharide (LPS) is implicated in increasing mortality in patients with alcoholic hepatitis but the underlying mechanisms are not well characterised. The objective of this study was to characterise neutrophil function, LPS and cytokine concentrations within the splanchnic circulation of alcoholic cirr...

journal_title：Scientific reports

authors： Macnaughtan J,Mookerjee RP,van der Merwe S,Jalan R

更新日期：2017-01-04 00:00:00

abstract：:Hepatitis E Virus-like particles self-assemble in to noninfectious nanocapsids that are resistant to proteolytic/acidic mucosal delivery conditions. Previously, the nanocapsid was engineered to specifically bind and enter breast cancer cells, where successful tumor targeting was demonstrated in animal models. In the p...

journal_title：Scientific reports

authors： Stark MC,Baikoghli MA,Lahtinen T,Malola S,Xing L,Nguyen M,Nguyen M,Sikaroudi A,Marjomäki V,Häkkinen H,Cheng RH

更新日期：2017-12-06 00:00:00

abstract：:Circulating microRNAs (c-miRNAs) in human plasma have been described as a potential marker of exercise. The present study investigated the effects of three acute resistance training (RT) protocols on the time-course changes of the c-miRNAs profiles in young males. The subjects (n = 45) were randomly divided into three...

journal_title：Scientific reports

authors： Cui S,Sun B,Yin X,Guo X,Chao D,Zhang C,Zhang CY,Chen X,Ma J

更新日期：2017-05-19 00:00:00

abstract：:Breast cancer is a heterogeneous disease with differences in its clinical, molecular and biological features. Traditionally, immunohistochemical markers together with clinicopathologic parameters are used to classify breast cancer and to predict disease outcome. Triple-negative breast cancer (TNBC) is a particular typ...

journal_title：Scientific reports

authors： Manica GC,Ribeiro CF,Oliveira MA,Pereira IT,Chequin A,Ramos EA,Klassen LM,Sebastião AP,Alvarenga LM,Zanata SM,Noronha L,Rabinovich I,Costa FF,Souza EM,Klassen G

更新日期：2017-03-15 00:00:00

abstract：:Driven diffusive systems have been a paradigm for modelling many physical, chemical, and biological transport processes. In the systems, spatial correlation plays an important role in the emergence of a variety of nonequilibrium phenomena and exhibits rich features such as pronounced oscillations. However, the lack of...

journal_title：Scientific reports

authors： Hao QY,Jiang R,Hu MB,Jia B,Wang WX

更新日期：2016-01-25 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Fossum KN,Ovadnevaite J,Ceburnis D,Dall'Osto M,Marullo S,Bellacicco M,Simó R,Liu D,Flynn M,Zuend A,O'Dowd C

更新日期：2019-07-18 00:00:00

abstract：:Long Terminal Repeats (LTRs) are nearly identical DNA sequences found at either end of Human Endogenous Retroviruses (HERVs). The high sequence similarity that exists among different LTRs suggests they could be substrate of ectopic gene conversion events. To understand the extent to which gene conversion occurs and to...

journal_title：Scientific reports

authors： Trombetta B,Fantini G,D'Atanasio E,Sellitto D,Cruciani F

更新日期：2016-06-27 00:00:00

abstract：:Lead germanate-graphene nanosheets (PbGeO3-GNS) composites have been prepared by an efficient one-step, in-situ hydrothermal method and were used as anode materials for Li-ion batteries (LIBs). The PbGeO3 nanowires, around 100-200 nm in diameter, are highly encapsulated in a graphene matrix. The lithiation and de-lith...

journal_title：Scientific reports

authors： Wang J,Feng CQ,Sun ZQ,Chou SL,Liu HK,Wang JZ

更新日期：2014-11-13 00:00:00

abstract：:The DEAD-box RNA helicase DDX3 plays divergent roles in tumorigenesis, however, its function in mitosis is unclear. Immunofluorescence indicated that DDX3 localized to centrosome throughout the cell cycle and colocalized with centrosome-associated p53 during mitosis in HCT116 and U2OS cells. DDX3 depletion promoted ch...

journal_title：Scientific reports

authors： Chen WJ,Wang WT,Tsai TY,Li HK,Lee YW

更新日期：2017-08-25 00:00:00

abstract：:Males of hymenopteran insects, which include ants, bees and wasps, develop as haploids from unfertilized eggs. In order to accommodate their lack of homologous chromosome pairs, some hymenopterans such as the honeybee have been shown to produce haploid sperm through an abortive meiosis. We employed microscopic approac...

journal_title：Scientific reports

authors： Ferree PM,Aldrich JC,Jing XA,Norwood CT,Van Schaick MR,Cheema MS,Ausió J,Gowen BE

更新日期：2019-08-21 00:00:00

abstract：:Hedgehog interacting protein (Hhip) is essential for islet formation and beta-cell proliferation during pancreatic development; abnormally elevated Hhip expression has been linked to human pancreatitis. Here, we investigate the role of Hhip in modulating insulin secretion in adult Hhip mice (Hhip +/- vs. Hhip+/+) fed ...

journal_title：Scientific reports

authors： Nchienzia H,Liao MC,Zhao XP,Chang SY,Lo CS,Chenier I,Ingelfinger JR,Chan JSD,Zhang SL

更新日期：2019-08-01 00:00:00

abstract：:During action observation, several visual features of observed actions can modulate the level of sensorimotor reactivity in the onlooker. Among possibly relevant parameters, one of the less investigated in humans is the visual perspective from which actions are observed. In the present EEG study, we assessed the react...

journal_title：Scientific reports

authors： Angelini M,Fabbri-Destro M,Lopomo NF,Gobbo M,Rizzolatti G,Avanzini P

更新日期：2018-08-20 00:00:00

abstract：:In theory, a few naturally occurring evolutionary changes in the genome of a model organism may have little or no observable impact on its wild type phenotype, and yet still substantially impact the phenotypes of mutant strains through epistasis. To see if this is happening in a model organism, we obtained nine differ...

journal_title：Scientific reports

authors： Bradley MD,Neu D,Bahar F,Welch RD

更新日期：2016-12-01 00:00:00

abstract：:Ultrafine-grained die-upset Nd-Fe-B magnets are of importance because they provide a wide researching space to redesign the textured structures. Here is presented a route to obtain a new die-upset magnet with substantially improved magnetic properties. After experiencing the optimized heat treatment, both the coercivi...

journal_title：Scientific reports

authors： Wang Z,Ju J,Wang J,Yin W,Chen R,Li M,Jin C,Tang X,Lee D,Yan A

更新日期：2016-12-06 00:00:00

abstract：:Cooperative behaviors are common in humans, and they are the fundamental basis of our society. Theoretical and experimental studies have modeled environments where the behaviors of humans, or agents, have been restricted to analyze their social behavior. However, it is important that such studies can be generalized to...

journal_title：Scientific reports

authors： Takano M,Wada K,Fukuda I

更新日期：2015-07-28 00:00:00

abstract：:Interference of two combined white light beams produces Newton colors if one of the beams is retarded relative to the other by from 400 nm to 2000 nm. In this case the corresponding interfering spectral components are added as two scalars at the beam combination. If the retardance is below 400 nm the two-beam interfer...

journal_title：Scientific reports

authors： Shribak M

更新日期：2015-11-27 00:00:00

abstract：:This work demonstrates the first application of direct broadband (1 GHz-30 GHz) quality (Q) factor measurements of the uniform precession mode in magnetised garnet spheres for the accurate determination of the room-temperature intrinsic ferromagnetic linewidth (ΔH). The spheres were enclosed in a subwavelength cavity,...

journal_title：Scientific reports

authors： Pacewicz A,Krupka J,Salski B,Aleshkevych P,Kopyt P

更新日期：2019-07-01 00:00:00

abstract：:We study heat dissipation of a multi-wall carbon nanotube (MWCNT) device fabricated from two crossed nanotubes on a SiNx substrate under the influence of a constant (DC) electric bias. By monitoring the temperature of the substrate, we observe negligible Joule heating within the nanotube lattice itself and instead hea...

journal_title：Scientific reports

authors： Voskanian N,Olsson E,Cumings J

更新日期：2019-07-25 00:00:00

abstract：:The CRISPR/Cas9 system is a powerful method of editing genes by randomly introducing errors into the target sites. Here, we describe a CRISPR-based test for gene essentiality (CRISPR-E test) that allows the identification of essential genes. Specifically, we use sgRNA-mediated CRISPR/Cas9 to target the open reading fr...

journal_title：Scientific reports

authors： You Y,Ramachandra SG,Jin T

更新日期：2020-09-08 00:00:00

abstract：:Facial emotion perception plays a key role in interpersonal communication and is a precursor for a variety of socio-cognitive abilities. One brain region thought to support emotion perception is the inferior frontal cortex (IFC). The current study aimed to examine whether modulating neural activity in the IFC using hi...

journal_title：Scientific reports

authors： Penton T,Dixon L,Evans LJ,Banissy MJ

更新日期：2017-09-12 00:00:00

abstract：:Reef sharks are vulnerable predators experiencing severe population declines mainly due to overexploitation. However, beyond direct exploitation, human activities can produce indirect or sub-lethal effects such as behavioral alterations. Such alterations are well known for terrestrial fauna but poorly documented for m...

journal_title：Scientific reports

authors： Juhel JB,Vigliola L,Wantiez L,Letessier TB,Meeuwig JJ,Mouillot D

更新日期：2019-02-27 00:00:00

abstract：:High-Q microresonator is perceived as a promising platform for optical frequency comb generation, via dissipative soliton formation. In order to achieve a higher quality factor and obtain the necessary anomalous dispersion, multi-mode waveguides were previously implemented in Si3N4 microresonators. However, coupling b...

journal_title：Scientific reports

authors： Huang SW,Liu H,Yang J,Yu M,Kwong DL,Wong CW

更新日期：2016-05-16 00:00:00

abstract：:Freeze-thaw cycles are predicted to increase in cold temperate regions. The potential influence of the interactions of freeze-thaw cycles and agrochemicals on the release of Cd into river water is unknown. In this study, the interactions of freeze-thaw cycles and chlorpyrifos (FC) on Cd mobility in soils were analysed...

journal_title：Scientific reports

authors： Wang F,Ouyang W,Hao F,Jiao W,Shan Y,Lin C

更新日期：2016-06-02 00:00:00

abstract：:Controlling dynamics of a network from any initial state to a final desired state has many applications in different disciplines from engineering to biology and social sciences. In this work, we optimize the network structure for pinning control. The problem is formulated as four optimization tasks: i) optimizing the ...

journal_title：Scientific reports

authors： Orouskhani Y,Jalili M,Yu X

更新日期：2016-04-12 00:00:00

abstract：:Two polar vessels, Akademik Shokalskiy and Xuelong, were trapped by thick sea ice in the Antarctic coastal region just to the west of 144°E and between 66.5°S and 67°S in late December 2013. This event demonstrated the rapid establishment of extreme Antarctic sea ice conditions on synoptic time scales. The event was a...

journal_title：Scientific reports

authors： Wang Z,Turner J,Sun B,Li B,Liu C

更新日期：2014-06-17 00:00:00

abstract：:Trophic variation in food web structure occurs among and within ecosystems. The magnitude of variation, however, differs from system to system. In ephemeral pond ecosystems, temporal dynamics are relatively more important than in many systems given that hydroperiod is the ultimate factor determining the presence of an...

journal_title：Scientific reports

authors： Dalu T,Wasserman RJ,Froneman PW,Weyl OLF

更新日期：2017-08-08 00:00:00