Time-course responses of circulating microRNAs to three resistance training protocols in healthy young men.

Abstract:

:Circulating microRNAs (c-miRNAs) in human plasma have been described as a potential marker of exercise. The present study investigated the effects of three acute resistance training (RT) protocols on the time-course changes of the c-miRNAs profiles in young males. The subjects (n = 45) were randomly divided into three groups: muscular strength endurance (SE), muscular hypertrophy (MH) and maximum strength (MS). Venous blood samples were obtained before exercise and immediately, 1 h and 24 h after each RT protocol to assess the following biological parameters: c-miRNAs, anabolic and catabolic hormones, inflammatory cytokines and muscle damage markers. The results revealed that the levels of two c-miRNAs (miR-208b and miR-532), six c-miRNAs (miR-133a, miR-133b, miR-206, miR-181a, miR-21 and miR-221) and two c-miRNAs (miR-133a and miR-133b) changed significantly in response to the SE, MH and MS protocols (p < 0.05), respectively. The nature and dynamic processes of the c-miRNAs response were likely influenced by the RT modality and intensity. Moreover, miR-532 was negatively correlated with insulin-like growth factor-1 and positively correlated with interleukin-10, whereas miR-133a was negatively correlated with cortisol and positively correlated with testosterone/cortisol. These findings suggest that these c-miRNAs may serve as markers for monitoring the RT responses.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Cui S,Sun B,Yin X,Guo X,Chao D,Zhang C,Zhang CY,Chen X,Ma J

doi

10.1038/s41598-017-02294-y

subject

Has Abstract

pub_date

2017-05-19 00:00:00

pages

2203

issue

1

issn

2045-2322

pii

10.1038/s41598-017-02294-y

journal_volume

7

pub_type

杂志文章
  • Serum Vitamin D Level Does not Affect The Sensitivity of Parathyroid Adenoma Localization Tests.

    abstract::The aim of the present study was to evaluate the predictive value of 25-hydroxyvitamin D, calcium and parathormone level, co-existence of thyroid nodule, thyroidectomy history and adenoma volume on the success of neck ultrasound (US) and technetium-99m sestamibi (MIBI) scan in primary hyperparathyroidism (PHP) patient...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-48536-z

    authors: Sencar ME,Sakiz D,Unsal IO,Hepsen S,Calapkulu M,Gumus P,Ucan B,Ozbek M,Cakal E

    更新日期:2019-08-19 00:00:00

  • The association between BMI and mortality using early adulthood BMI as an instrumental variable for midlife BMI.

    abstract::The article aims to describe the association between midlife body mass index (BMI) and cardiovascular disease (CVD)- and all-cause mortality, and to use early adulthood BMI as an instrumental variable for midlife BMI, in order to obtain an estimate less distorted by midlife confounders and reverse causality. Data from...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-29089-z

    authors: Kjøllesdal MKR,Smith GD,Ariansen I,Kinge JM,Degerud E,Næss Ø

    更新日期:2018-07-31 00:00:00

  • Minicollagen cysteine-rich domains encode distinct modes of polymerization to form stable nematocyst capsules.

    abstract::The stinging capsules of cnidarians, nematocysts, function as harpoon-like organelles with unusual biomechanical properties. The nanosecond discharge of the nematocyst requires a dense protein network of the capsule structure withstanding an internal pressure of up to 150 bar. Main components of the capsule are short ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep25709

    authors: Tursch A,Mercadante D,Tennigkeit J,Gräter F,Özbek S

    更新日期:2016-05-11 00:00:00

  • An atypical phosphodiesterase capable of degrading haloalkyl phosphate diesters from Sphingobium sp. strain TCM1.

    abstract::Sphingobium sp. strain TCM1 can degrade tris(2-chloroethyl) phosphate (TCEP) to inorganic phosphate and 2-chloroethanol. A phosphotriesterase (PTE), phosphodiesterase (PDE) and phosphomonoesterase (PME) are believed to be involved in the degradation of TCEP. The PTE and PME that respectively catalyze the first and thi...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-03142-9

    authors: Abe K,Mukai N,Morooka Y,Makino T,Oshima K,Takahashi S,Kera Y

    更新日期:2017-06-06 00:00:00

  • Publisher Correction: PP2A inhibition from LB100 therapy enhances daunorubicin cytotoxicity in secondary acute myeloid leukemia via miR-181b-1 upregulation.

    abstract::A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper. ...

    journal_title:Scientific reports

    pub_type: 杂志文章,已发布勘误

    doi:10.1038/s41598-017-14858-z

    authors: Hu C,Yu M,Ren Y,Li K,Maggio DM,Mei C,Ye L,Wei J,Jin J,Zhuang Z,Tong H

    更新日期:2017-11-07 00:00:00

  • Silver Nanoparticles Impact Biofilm Communities and Mussel Settlement.

    abstract::Silver nanoparticles (AgNPs) demonstrating good antimicrobial activity are widely used in many fields. However, the impact of AgNPs on the community structures of marine biofilms that drive biogeochemical cycling processes and the recruitment of marine invertebrate larvae remains unknown. Here, we employed MiSeq seque...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep37406

    authors: Yang JL,Li YF,Liang X,Guo XP,Ding DW,Zhang D,Zhou S,Bao WY,Bellou N,Dobretsov S

    更新日期:2016-11-21 00:00:00

  • Localized crystallization in shear bands of a metallic glass.

    abstract::Stress-induced viscous flow is the characteristic of atomic movements during plastic deformation of metallic glasses in the absence of substantial temperature increase, which suggests that stress state plays an important role in mechanically induced crystallization in a metallic glass. However, it is poorly understood...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep19358

    authors: Yan Z,Song K,Hu Y,Dai F,Chu Z,Eckert J

    更新日期:2016-01-13 00:00:00

  • Visualization of aquaionic splitting via iron corrosion.

    abstract::We report a water decomposition mode called 'Aquaionic Splitting (AiS)' by means of iron corrosion in aqueous solution. In this paper, we investigated the phenomenon by controlling the reaction between iron and water. A pseudo-sacrificial protection method with oil paint was employed to select the anode and cathode fo...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-58707-y

    authors: Murakami S,Zhang L,Watanabe S

    更新日期:2020-02-03 00:00:00

  • Towards Millimeter-wavelength: Transmission-Mode Fresnel-Zone Plate Lens Antennas using Plastic Material Porosity Control in Homogeneous Medium.

    abstract::We present two transmission-mode dielectric Fresnel-Zone Plate Lens (FZPL) antennas for use within the V-band spectrum. The proposed FZPs are realized via pure plastic material using two different additive manufacturing processes. The proposed FZP lenses are designed with half (λ/2) and quarter (λ/4) phase correction ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-23179-8

    authors: Pourahmadazar J,Denidni TA

    更新日期:2018-03-28 00:00:00

  • Potential for high yield with increased seedling density and decreased N fertilizer application under seedling-throwing rice cultivation.

    abstract::Fertilizer application for rice production has increased significantly in southern China to raise yields, but has led to problems with lodging, quality decline and environmental pollution. Therefore, research on fertilizer-saving cultivation technologies for high-yielding rice is necessary. A two-factor experiment was...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-36978-w

    authors: Liu Y,Li C,Fang B,Fang Y,Chen K,Zhang Y,Zhang H

    更新日期:2019-01-24 00:00:00

  • A combined method to quantify the retinal metabolic rate of oxygen using photoacoustic ophthalmoscopy and optical coherence tomography.

    abstract::Quantitatively determining physiological parameters at a microscopic level in the retina furthers the understanding of the molecular pathways of blinding diseases, such as diabetic retinopathy and glaucoma. An essential parameter, which has yet to be quantified noninvasively, is the retinal oxygen metabolic rate (rMRO...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep06525

    authors: Song W,Wei Q,Liu W,Liu T,Yi J,Sheibani N,Fawzi AA,Linsenmeier RA,Jiao S,Zhang HF

    更新日期:2014-10-06 00:00:00

  • Anodal tDCS over the primary motor cortex improves motor imagery benefits on postural control: A pilot study.

    abstract::Performing everyday actions requires fine postural control, which is a major focus of functional rehabilitation programs. Among the various range of training methods likely to improve balance and postural stability, motor imagery practice (MIP) yielded promising results. Transcranial direct current stimulation (tDCS) ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-00509-w

    authors: Saruco E,Di Rienzo F,Nunez-Nagy S,Rubio-Gonzalez MA,Jackson PL,Collet C,Saimpont A,Guillot A

    更新日期:2017-03-28 00:00:00

  • Balancing Speed and Coverage by Sequential Seeding in Complex Networks.

    abstract::Information spreading in complex networks is often modeled as diffusing information with certain probability from nodes that possess it to their neighbors that do not. Information cascades are triggered when the activation of a set of initial nodes - seeds - results in diffusion to large number of nodes. Here, several...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-00937-8

    authors: Jankowski J,Bródka P,Kazienko P,Szymanski BK,Michalski R,Kajdanowicz T

    更新日期:2017-04-18 00:00:00

  • RNA-Seq analysis and comparison of corneal epithelium in keratoconus and myopia patients.

    abstract::Keratoconus is a common degenerative corneal disease that can lead to significant visual morbidity, and both genetic and environmental factors have been implicated in its pathogenesis. We compared the transcriptome of keratoconus and control epithelium using RNA-Seq. Epithelial tissues were obtained prior to surgery f...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-18480-x

    authors: You J,Corley SM,Wen L,Hodge C,Höllhumer R,Madigan MC,Wilkins MR,Sutton G

    更新日期:2018-01-10 00:00:00

  • Scaling Effect of Phosphorene Nanoribbon - Uncovering the Origin of Asymmetric Current Transport.

    abstract::In this paper, phosphorene nanoribbons (PNRs) are theoretically studied using a multiscale simulation flow from the ab initio level to the tight binding (TB) level. The scaling effects of both armchair PNRs (aPNRs) and zigzag PNRs (zPNRs) from material properties to device properties are explored. The much larger effe...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep38009

    authors: Lv Y,Chang S,Huang Q,Wang H,He J

    更新日期:2016-11-29 00:00:00

  • Responses of the Hybrid between Sphagneticola trilobata and Sphagneticola calendulacea to Low Temperature and Weak Light Characteristic in South China.

    abstract::Hybridization between exotic and native species is of great interest to evolutionary biologists and ecologists because it usually shows a quick evolution of species and invasiveness. It has been reported that such hybridization frequently increases the adaptation and aggressiveness of the new hybrids. A hybrid between...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep16906

    authors: Sun Z,Chen Y,Schaefer V,Liang H,Li W,Huang S,Peng C

    更新日期:2015-11-19 00:00:00

  • Botulinum neurotoxin-encoding plasmids can be conjugatively transferred to diverse clostridial strains.

    abstract::Most Group I Clostridium botulinum strains harbor botulinum neurotoxin (bont) genes on their chromosome, while some carry these genes (including bont/a, bont/b, and bont/f) on large plasmids. Prior work in our laboratory demonstrated that Group I BoNT plasmids were mobilized to C. botulinum recipient strains containin...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-21342-9

    authors: Nawrocki EM,Bradshaw M,Johnson EA

    更新日期:2018-02-15 00:00:00

  • Common dysfunctional variants of ABCG2 have stronger impact on hyperuricemia progression than typical environmental risk factors.

    abstract::Gout/hyperuricemia is a common multifactorial disease having typical environmental risks. Recently, common dysfunctional variants of ABCG2, a urate exporter gene also known as BCRP, are revealed to be a major cause of gout/hyperuricemia. Here, we compared the influence of ABCG2 dysfunction on serum uric acid (SUA) lev...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep05227

    authors: Nakayama A,Matsuo H,Nakaoka H,Nakamura T,Nakashima H,Takada Y,Oikawa Y,Takada T,Sakiyama M,Shimizu S,Kawamura Y,Chiba T,Abe J,Wakai K,Kawai S,Okada R,Tamura T,Shichijo Y,Akashi A,Suzuki H,Hosoya T,Sakurai Y,Ic

    更新日期:2014-06-09 00:00:00

  • Scaling of geometric quantum discord close to a topological phase transition.

    abstract::Quantum phase transition is one of the most interesting aspects in quantum many-body systems. Recently, geometric quantum discord has been introduced to signature the critical behavior of various quantum systems. However, it is well-known that topological quantum phase transition can not be described by the convention...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep04473

    authors: Shan CJ,Cheng WW,Liu JB,Cheng YS,Liu TK

    更新日期:2014-03-26 00:00:00

  • Hepatic overproduction of 13-HODE due to ALOX15 upregulation contributes to alcohol-induced liver injury in mice.

    abstract::Chronic alcohol feeding causes lipid accumulation and apoptosis in the liver. This study investigated the role of bioactive lipid metabolites in alcohol-induced liver damage and tested the potential of targeting arachidonate 15-lipoxygenase (ALOX15) in treating alcoholic liver disease (ALD). Results showed that chroni...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-02759-0

    authors: Zhang W,Zhong W,Sun Q,Sun X,Zhou Z

    更新日期:2017-08-21 00:00:00

  • Structure and co-occurrence patterns in microbial communities under acute environmental stress reveal ecological factors fostering resilience.

    abstract::Understanding the factors that modulate bacterial community assembly in natural soils is a longstanding challenge in microbial community ecology. In this work, we compared two microbial co-occurrence networks representing bacterial soil communities from two different sections of a pH, temperature and humidity gradient...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-23931-0

    authors: Mandakovic D,Rojas C,Maldonado J,Latorre M,Travisany D,Delage E,Bihouée A,Jean G,Díaz FP,Fernández-Gómez B,Cabrera P,Gaete A,Latorre C,Gutiérrez RA,Maass A,Cambiazo V,Navarrete SA,Eveillard D,González M

    更新日期:2018-04-12 00:00:00

  • Biogeographic parallels in thermal tolerance and gene expression variation under temperature stress in a widespread bumble bee.

    abstract::Global temperature changes have emphasized the need to understand how species adapt to thermal stress across their ranges. Genetic mechanisms may contribute to variation in thermal tolerance, providing evidence for how organisms adapt to local environments. We determine physiological thermal limits and characterize ge...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-73391-8

    authors: Pimsler ML,Oyen KJ,Herndon JD,Jackson JM,Strange JP,Dillon ME,Lozier JD

    更新日期:2020-10-13 00:00:00

  • Sugar based N,N'-didodecyl-N,N'digluconamideethylenediamine gemini surfactant as corrosion inhibitor for mild steel in 3.5% NaCl solution-effect of synergistic KI additive.

    abstract::The inhibitory behaviour of non-ionic sugar based N,N'-didodecyl-N,N'-digluconamideethylenediamine gemini surfactant, designated as Glu(12)-2-Glu(12) on mild steel (MS) corrosion in 3.5% NaCl at 30-60 °C was explored using weight loss, PDP, EIS and SEM/EDAX/AFM techniques. The compound inhibited the corrosion of mild ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-21175-6

    authors: Aslam R,Mobin M,Aslam J,Lgaz H

    更新日期:2018-02-27 00:00:00

  • A Low Permeability Microfluidic Blood-Brain Barrier Platform with Direct Contact between Perfusable Vascular Network and Astrocytes.

    abstract::A novel three dimensional blood brain barrier (BBB) platform was developed by independently supplying different types of media to separate cell types within a single device. One channel (vascular channel, VC) is connected to the inner lumen of the vascular network while the other supplies media to the neural cells (ne...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-07416-0

    authors: Bang S,Lee SR,Ko J,Son K,Tahk D,Ahn J,Im C,Jeon NL

    更新日期:2017-08-14 00:00:00

  • Robust Statistical Detection of Power-Law Cross-Correlation.

    abstract::We show that widely used approaches in statistical physics incorrectly indicate the existence of power-law cross-correlations between financial stock market fluctuations measured over several years and the neuronal activity of the human brain lasting for only a few minutes. While such cross-correlations are nonsensica...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep27089

    authors: Blythe DA,Nikulin VV,Müller KR

    更新日期:2016-06-02 00:00:00

  • Evidence of a two-dimensional glass transition in graphene: Insights from molecular simulations.

    abstract::Liquids exhibit a sudden increase in viscosity when cooled fast enough, avoiding thermodynamically predicted route of crystallization. This phenomenon, known as glass transition, leads to the formation of non-periodic structures known as glasses. Extensive studies have been conducted on model materials to understand g...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-41231-z

    authors: Ravinder R,Kumar R,Agarwal M,Krishnan NMA

    更新日期:2019-03-14 00:00:00

  • A new approach to chemotherapy: drug-induced differentiation kills African trypanosomes.

    abstract::Human African trypanosomiasis (sleeping sickness) is a neglected tropical disease caused by Trypanosoma brucei spp. The parasites are transmitted by tsetse flies and adapt to their different hosts and environments by undergoing a series of developmental changes. During differentiation, the trypanosome alters its prote...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep22451

    authors: Wenzler T,Schumann Burkard G,Schmidt RS,Mäser P,Bergner A,Roditi I,Brun R

    更新日期:2016-03-02 00:00:00

  • Orbit-induced spin squeezing in a spin-orbit coupled Bose-Einstein condensate.

    abstract::In recent pioneer experiment, a strong spin-orbit coupling, with equal Rashba and Dresselhaus strengths, has been created in a trapped Bose-Einstein condensate. Moreover, many exotic superfluid phenomena induced by this strong spin-orbit coupling have been predicted. In this report, we show that this novel spin-orbit ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep03166

    authors: Lian J,Yu L,Liang JQ,Chen G,Jia S

    更新日期:2013-11-07 00:00:00

  • Chromium exposure and incidence of metabolic syndrome among American young adults over a 23-year follow-up: the CARDIA Trace Element Study.

    abstract::Studies suggest that chromium deficiency is associated with elevated levels of fasting blood glucose, circulating insulin, cholesterol and triglycerides, and decreased proportion of lean body mass. However, data directly relating chromium levels to metabolic syndrome (MetS) risk are lacking. A total of 3,648 American ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep15606

    authors: Bai J,Xun P,Morris S,Jacobs DR Jr,Liu K,He K

    更新日期:2015-10-22 00:00:00

  • The origin of sheep settlement in Western Mediterranean.

    abstract::The arrival of Neolithic culture in North Africa, especially domestic animals has been essentially documented from archaeological records. As the data relative to sheep are scarce, we studied the genetic relationship between Moroccan sheep breeds and Mediterranean ones using the sequencing of 628 bp of the mitochondri...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-67246-5

    authors: Kandoussi A,Boujenane I,Auger C,Serranito B,Germot A,Piro M,Maftah A,Badaoui B,Petit D

    更新日期:2020-06-23 00:00:00