A combined method to quantify the retinal metabolic rate of oxygen using photoacoustic ophthalmoscopy and optical coherence tomography.

abstract：:A millisecond micro-RNA separation of a mixture of total RNA and genomic DNA, extracted from cultured HeLa cells, was successfully achieved using a hybrid structure of nanopillars and nanoslits contained inside a microchannel. The nanopillars, 250-nm in diameter and 100-nm in height, were fabricated with a 750-nm spac...

journal_title：Scientific reports

authors： Wu Q,Kaji N,Yasui T,Rahong S,Yanagida T,Kanai M,Nagashima K,Tokeshi M,Kawai T,Baba Y

更新日期：2017-03-08 00:00:00

abstract：:During locomotion, the human ankle-foot system dynamically alters its gearing, or leverage of the ankle joint on the ground. Shifting ankle-foot gearing regulates speed of plantarflexor (i.e., calf muscle) contraction, which influences economy of force production. Here, we tested the hypothesis that manipulating ankle...

journal_title：Scientific reports

authors： Ray SF,Takahashi KZ

更新日期：2020-05-29 00:00:00

abstract：:Thrombocytopenia is common in patients with dengue virus (DENV) infections. With a focus on understanding the possible mechanism of thrombocytopenia in DENV infections we described a direct correlation between activation and depletion of platelets in patients. Our data showed a sharp decrease in platelet counts at day...

journal_title：Scientific reports

authors： Ojha A,Nandi D,Batra H,Singhal R,Annarapu GK,Bhattacharyya S,Seth T,Dar L,Medigeshi GR,Vrati S,Vikram NK,Guchhait P

更新日期：2017-01-31 00:00:00

abstract：:Despite strengthened antimicrobial therapy, biofilm infections of Acinetobacter baumannii are associated with poor prognosis and limited therapeutic options. Assessing antibiotics on planktonic bacteria can result in failure against biofilm infections. Currently, antibiotics to treat biofilm infections are administere...

journal_title：Scientific reports

authors： Wannigama DL,Hurst C,Pearson L,Saethang T,Singkham-In U,Luk-In S,Storer RJ,Chatsuwan T

更新日期：2019-04-19 00:00:00

abstract：:The objective was to establish and evaluate a method for manufacture of custom trays for edentulous jaws using computer aided design and fused deposition modeling (FDM) technologies. A digital method for design the custom trays for edentulous jaws was established. The tissue surface data of ten standard mandibular ede...

journal_title：Scientific reports

authors： Chen H,Yang X,Chen L,Wang Y,Sun Y

更新日期：2016-01-14 00:00:00

abstract：:INK4 locus at chromosome 9p21 has been reported to be associated with primary open angle glaucoma (POAG) and its subtypes along with the associated optic disc parameters across the populations of European, Japanese and African ancestries. The locus encodes three tumor suppressor genes namely CDKN2A, ARF, CDKN2B and a ...

journal_title：Scientific reports

authors： Vishal M,Sharma A,Kaurani L,Chakraborty S,Ray J,Sen A,Mukhopadhyay A,Ray K

更新日期：2014-05-30 00:00:00

abstract：:Although early diagnosis and treatment reduce the risk of blindness from glaucoma, the decision on whether or not to begin treatment in patients with suspected glaucoma is often a dilemma because the majority of patients never develop definite glaucoma. A growing body of evidences suggests that posterior bowing of the...

journal_title：Scientific reports

authors： Kim JA,Kim TW,Weinreb RN,Lee EJ,Girard MJA,Mari JM

更新日期：2018-01-15 00:00:00

abstract：:The application of a lattice structure in the lightweight design of compressor impellers can reduce their mass and moment of inertia, hence improving the effective carrying of aircraft and reducing the start and braking moments of the impeller. The feasibility of a processing-lattice compressor impeller is the prerequ...

journal_title：Scientific reports

authors： Jia D,Li F,Zhang Y

更新日期：2020-01-17 00:00:00

abstract：:Gram-positive bacteria homeostasis and antibiotic resistance mechanisms are dependent on the intricate architecture of the cell wall, where amidated peptidoglycan plays an important role. The amidation reaction is carried out by the bi-enzymatic complex MurT-GatD, for which biochemical and structural information is ve...

journal_title：Scientific reports

authors： Leisico F,V Vieira D,Figueiredo TA,Silva M,Cabrita EJ,Sobral RG,Ludovice AM,Trincão J,Romão MJ,de Lencastre H,Santos-Silva T

更新日期：2018-03-28 00:00:00

abstract：:The Acoustic Complexity Index (ACI) is increasingly applied to the study of biodiversity in aquatic habitats. However, it remains unknown which types of acoustic information are highlighted by this index in underwater environments. This study explored the robustness of the ACI to fine variations in fish sound abundanc...

journal_title：Scientific reports

authors： Bolgan M,Amorim MCP,Fonseca PJ,Di Iorio L,Parmentier E

更新日期：2018-07-12 00:00:00

abstract：:Pulmonary fibrosis is a serious lung disorder that can lead to respiratory failure. Here we show that transgenic mice expressing active renin from the liver (RenTgMK) developed progressive pulmonary fibrosis leading to impaired pulmonary function. Histological analyses revealed a marked increase in extracellular matri...

journal_title：Scientific reports

authors： Wang J,Chen L,Chen B,Meliton A,Liu SQ,Shi Y,Liu T,Deb DK,Solway J,Li YC

更新日期：2015-10-23 00:00:00

abstract：:The present study reports the use of one-dimensional carbon wrapped VO2(M) nanofiber (VO2(M)/C) as a cost-effective counter electrode for dye-sensitized solar cells (DSSCs); where M denotes monoclinic crystal system. Uniform short length nanofiber was synthesised by a sol-gel based simple and versatile electrospinning...

journal_title：Scientific reports

authors： Gnanasekar S,Kollu P,Jeong SK,Grace AN

更新日期：2019-03-26 00:00:00

abstract：:Heating on the microscale using focused lasers gave rise to recent applications, e.g., in biomedicine, biology and microfluidics, especially using gold nanoparticles as efficient nanoabsorbers of light. However, such an approach naturally leads to nonuniform, Gaussian-like temperature distributions due to the diffusiv...

journal_title：Scientific reports

authors： Durdevic L,Robert HML,Wattellier B,Monneret S,Baffou G

更新日期：2019-03-15 00:00:00

abstract：:Fat deposition of beef cattle varies between breeds. However, the regulation mechanism is still not elucidated completely at molecular level. In the present study, we comparatively analyzed transcriptome of subcutaneous adipose tissue between Wagyu and Holstein cattle with a significant difference in fat deposition to...

journal_title：Scientific reports

authors： Huang W,Guo Y,Du W,Zhang X,Li A,Miao X

更新日期：2017-07-13 00:00:00

abstract：:Topological quantum computation has been extensively studied in the past decades due to its robustness against decoherence. One way to realize the topological quantum computation is by adiabatic evolutions-it requires relatively long time to complete a gate, so the speed of quantum computation slows down. In this work...

journal_title：Scientific reports

authors： Shi ZC,Wang W,Yi XX

更新日期：2016-02-25 00:00:00

abstract：:Textile forms of solar cells possess special advantages over other types of solar cells, including their light weight, high flexibility, and mechanical robustness. Recent demand for wearable devices has promoted interest in the development of high-efficiency textile-based solar cells for energy suppliers. However, the...

journal_title：Scientific reports

authors： Yun MJ,Cha SI,Seo SH,Lee DY

更新日期：2014-06-24 00:00:00

abstract：:Herein, triphenyltin (TPT) biodegradation efficiency and its transformation pathway have been elucidated. To better understand the molecular mechanism of TPT degradation, the interactions between amino acids, primary structures, and quaternary conformations of effector proteins and TPT were studied. The results verifi...

journal_title：Scientific reports

authors： Wang L,Ye J,Ou H,Qin H,Long Y,Ke J

更新日期：2017-06-23 00:00:00

abstract：:Mind wandering (MW) refers to the disengagement of attention from the external environment and the generation of thoughts unrelated to the task at hand. It is a ubiquitous cognitive process resulting in lapses of attention. MW imposes a negative impact on attention-based task performance, but also has been associated ...

journal_title：Scientific reports

authors： Leszczynski M,Chaieb L,Reber TP,Derner M,Axmacher N,Fell J

更新日期：2017-08-31 00:00:00

abstract：:Radiotherapy with protons and heavier ions landmarks a novel era in the field of high-precision cancer therapy. To identify patients most benefiting from this technologically demanding therapy, fast assessment of comparative treatment plans utilizing different ion species is urgently needed. Moreover, to overcome unce...

journal_title：Scientific reports

authors： Mein S,Choi K,Kopp B,Tessonnier T,Bauer J,Ferrari A,Haberer T,Debus J,Abdollahi A,Mairani A

更新日期：2018-10-04 00:00:00

abstract：:A large outbreak of dengue, with the most documented cases, occurred in Guangdong China in 2014. Epidemiological studies and phylogenetic analysis of the isolated dengue virus (DENV) showed this outbreak was attributed to multiple sources and caused by at least two genotypes of DENV-1 (Genotypes I and III) and two gen...

journal_title：Scientific reports

authors： Shen SQ,Wei HX,Fu YH,Zhang H,Mo QY,Wang XJ,Deng SQ,Zhao W,Liu Y,Feng XS,Chen W,Peng HJ

更新日期：2015-11-23 00:00:00

abstract：:Genome engineering is a rapidly evolving field that benefits from the availability of different tools that can be used to perform genome manipulation tasks. We describe here the development of the Flp-TAL recombinases that can target genomic FRT-like sequences in their native chromosomal locations. Flp-TAL recombinase...

journal_title：Scientific reports

authors： Voziyanova E,Li F,Shah R,Voziyanov Y

更新日期：2020-10-15 00:00:00

abstract：:Hepatic stellate cells (HSCs) known as "master producers" and macrophages as "master regulators", are the key cell types that strongly contribute to the progression of liver fibrosis. Since Notch signaling regulates multiple cellular processes, we aimed to study the role of Notch signaling in HSCs differentiation and ...

journal_title：Scientific reports

authors： Bansal R,van Baarlen J,Storm G,Prakash J

更新日期：2015-12-14 00:00:00

abstract：:The majority of genes encoding photosynthesis-associated proteins in the nucleus are induced by light during photomorphogenesis, allowing plants to establish photoautotrophic growth. Therefore, optimizing the protein import apparatus of plastids, designated as the translocon at the outer and inner envelope membranes o...

journal_title：Scientific reports

authors： Fukazawa H,Tada A,Richardson LGL,Kakizaki T,Uehara S,Ito-Inaba Y,Inaba T

更新日期：2020-11-20 00:00:00

abstract：:The overlap between pain and reward processing pathways leds researchers to hypothesize that there are interactions between them in the human brain. Two hypotheses have been proposed. The "competition hypothesis" posits that reward can reduce pain-related neural activity and vice versa. The "salience hypothesis" sugge...

journal_title：Scientific reports

authors： Cui F,Zhu X,Gu R,Luo YJ

更新日期：2016-05-19 00:00:00

abstract：:Reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR) is an accurate and fast method to measure gene expression. Reproducibility of the analyses is the main limitation of RT-qPCR experiments. Galaxy is an open, web-based, genomic workbench for a reproducible, transparent, and accessible scie...

journal_title：Scientific reports

authors： Zanardi N,Morini M,Tangaro MA,Zambelli F,Bosco MC,Varesio L,Eva A,Cangelosi D

更新日期：2019-11-26 00:00:00

abstract：:The potential of a spheroid tumor model composed of cells in different proliferative and metabolic states for the development of new anticancer strategies has been amply demonstrated. However, there is little or no information in the literature on the problems of reproducibility of data originating from experiments us...

journal_title：Scientific reports

authors： Zanoni M,Piccinini F,Arienti C,Zamagni A,Santi S,Polico R,Bevilacqua A,Tesei A

更新日期：2016-01-11 00:00:00

abstract：:Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases, yet current therapeutic treatments are inadequate due to a complex disease pathogenesis. The plant polyphenol apigenin has been shown to have anti-inflammatory and neuroprotective properties in a number of cell and animal models; however...

journal_title：Scientific reports

authors： Balez R,Steiner N,Engel M,Muñoz SS,Lum JS,Wu Y,Wang D,Vallotton P,Sachdev P,O'Connor M,Sidhu K,Münch G,Ooi L

更新日期：2016-08-12 00:00:00

abstract：:Adapters bind motor proteins to cargoes and therefore play essential roles in Kinesin-1 mediated intracellular transport. The regulatory mechanisms governing adapter functions and the spectrum of cargoes recognized by individual adapters remain poorly defined. Here, we show that cargoes transported by the Kinesin-1 ad...

journal_title：Scientific reports

authors： Butkevich E,Härtig W,Nikolov M,Erck C,Grosche J,Urlaub H,Schmidt CF,Klopfenstein DR,Chua JJ

更新日期：2016-06-01 00:00:00

abstract：:Seeded polymerisation of proteins forming amyloid fibres and their spread in tissues has been implicated in the pathogenesis of multiple neurodegenerative diseases: so called "prion-like" mechanisms. While ex vivo mammalian prions, composed of multichain assemblies of misfolded host-encoded prion protein (PrP), act as...

journal_title：Scientific reports

authors： Terry C,Harniman RL,Sells J,Wenborn A,Joiner S,Saibil HR,Miles MJ,Collinge J,Wadsworth JDF

更新日期：2019-01-23 00:00:00

abstract：:We propose an error correction procedure based on a cellular automaton, the sweep rule, which is applicable to a broad range of codes beyond topological quantum codes. For simplicity, however, we focus on the three-dimensional toric code on the rhombic dodecahedral lattice with boundaries and prove that the resulting ...

journal_title：Scientific reports

authors： Vasmer M,Browne DE,Kubica A

更新日期：2021-01-21 00:00:00