Abstract:
:In many countries numbers of adults with cystic fibrosis (CF) exceed that of children, with median survival predicted to surpass 50 years. Increasing longevity is, in part, due to intensive therapies including eradication of early infection and suppressive therapies and pulmonary exacerbations. Initial infections with common CF pathogens are thought to arise from the natural environment. We review the impact of climate and environment on infection in CF. Specifically, several studies indicate that higher ambient temperatures, proximity to the equator and the summer season may be linked to the increased prevalence of Pseudomonas aeruginosa in people with CF. The environment may also play an important role in the acquisition of Gram negative organisms other than P. aeruginosa. There is emerging data suggesting that climatic and environmental factors are likely to impact on the risk of infection with NTM and fungi in people which are found extensively throughout the natural environment.
journal_name
Expert Rev Respir Medjournal_title
Expert review of respiratory medicineauthors
Ramsay KA,Stockwell RE,Bell SC,Kidd TJdoi
10.1586/17476348.2016.1162715subject
Has Abstractpub_date
2016-01-01 00:00:00pages
505-19issue
5eissn
1747-6348issn
1747-6356journal_volume
10pub_type
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journal_title:Expert review of respiratory medicine
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journal_title:Expert review of respiratory medicine
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journal_title:Expert review of respiratory medicine
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journal_title:Expert review of respiratory medicine
pub_type: 杂志文章
doi:10.1586/17476348.2.3.381
更新日期:2008-06-01 00:00:00
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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更新日期:2015-04-01 00:00:00
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journal_title:Expert review of respiratory medicine
pub_type: 杂志文章,评审
doi:10.1080/17476348.2018.1429921
更新日期:2018-03-01 00:00:00
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journal_title:Expert review of respiratory medicine
pub_type: 杂志文章,评审
doi:10.1586/ers.11.34
更新日期:2011-06-01 00:00:00
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pub_type: 杂志文章,评审
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journal_title:Expert review of respiratory medicine
pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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journal_title:Expert review of respiratory medicine
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pub_type: 杂志文章,评审
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journal_title:Expert review of respiratory medicine
pub_type: 杂志文章,评审
doi:10.1080/17476348.2018.1475234
更新日期:2018-06-01 00:00:00
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journal_title:Expert review of respiratory medicine
pub_type: 杂志文章,评审
doi:10.1080/17476348.2018.1495562
更新日期:2018-08-01 00:00:00
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journal_title:Expert review of respiratory medicine
pub_type: 杂志文章,评审
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journal_title:Expert review of respiratory medicine
pub_type: 杂志文章,评审
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journal_title:Expert review of respiratory medicine
pub_type: 杂志文章
doi:10.1080/17476348.2017.1392242
更新日期:2017-12-01 00:00:00