Symbicort® Maintenance and Reliever Therapy (SMART) and the evolution of asthma management within the GINA guidelines.

abstract：INTRODUCTION:Cystic fibrosis-related diabetes (CFRD) is the end-point of a spectrum of glucose abnormalities in cystic fibrosis that begins with early insulin deficiency and ultimately results in accelerated nutritional decline and loss of lung function. Current diagnostic and management regimens are unable to entirely...

journal_title：Expert review of respiratory medicine

authors： Prentice B,Hameed S,Verge CF,Ooi CY,Jaffe A,Widger J

更新日期：2016-07-01 00:00:00

abstract：:Objectives: Pleurodesis is an important management option to palliate breathlessness in patients with malignant pleural effusion (MPE). This systematic review aimed to examine available literature for studies investigating factors that predict pleurodesis outcome.Methods: The healthcare databases advanced search (HDAS...

journal_title：Expert review of respiratory medicine

authors： Hassan M,Gadallah M,Mercer RM,Harriss E,Rahman NM

更新日期：2020-06-01 00:00:00

abstract：:Introduction: Detection and characterization of pulmonary nodules is an important issue, because the process is the first step in the management of lung cancers.Areas covered: Literature review was performed on May 15 2019 by using the PubMed, US National Library of Medicine National Institutes of Health, and the Nati...

journal_title：Expert review of respiratory medicine

authors： Kim TJ,Kim CH,Lee HY,Chung MJ,Shin SH,Lee KJ,Lee KS

更新日期：2020-02-01 00:00:00

abstract：:Innovations in surgery have significantly increased the number of procedures performed every year. While more individuals benefit from better surgical techniques and technology, a larger group of patients previously deemed ineligible for surgery now undergo high-complexity surgical procedures. Despite continuous impro...

journal_title：Expert review of respiratory medicine

authors： Restrepo RD,Braverman J

更新日期：2015-02-01 00:00:00

abstract：:Although wheezing illness is at its most prevalent in infancy and early childhood, its self-limiting nature in the majority poses considerable challenges in offering a long-term prognosis and in initiating long-term prophylaxis. Many of the established treatments in adults have not been adequately assessed in children...

journal_title：Expert review of respiratory medicine

authors： Helms PJ

更新日期：2009-04-01 00:00:00

abstract：:Asthma is a disease that affects approximately 7% of adults residing in the USA; the prevalence is even greater in children and approaches 10%. The CDC has reported that the overall prevalence of lifetime asthma is 10.5%. New-onset asthma is most often seen in children and is associated with atopy; however, the majori...

journal_title：Expert review of respiratory medicine

authors： Braman SS

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Approximately 14% of UK hospital in-patients receive supplemental oxygen therapy, only 57% have valid prescriptions. Oxygen must be optimally prescribed to ensure maximal therapeutic response whilst minimizing adverse outcomes (including fatality). This study investigates prescription compliance. METHODS:Al...

journal_title：Expert review of respiratory medicine

authors： Barrett R,Catangui E,Scott R

更新日期：2020-10-14 00:00:00

abstract：INTRODUCTION:N-acetyl-l-cysteine (NAC), a derivative of the naturally occurring amino acid l-cysteine, is a mucolytic agent that may also act as an antioxidant by providing cysteine intracellularly for increased production of glutathione. It is also used for the treatment of acetaminophen overdose. Areas covered: The r...

journal_title：Expert review of respiratory medicine

authors： Calzetta L,Matera MG,Rogliani P,Cazzola M

更新日期：2018-08-01 00:00:00

abstract：:Erdosteine is a multimechanism, mucolytic agent that decreases the sputum viscoelastic properties and bacterial adhesion to the cell membrane, endowed with bronchial anti-inflammatory activity and a scavenging effect on free oxidant radicals. Erdosteine is a prodrug and metabolite I is the active metabolite of erdoste...

journal_title：Expert review of respiratory medicine

authors： Moretti M

更新日期：2007-12-01 00:00:00

abstract：:Dendritic cells (DCs) are the most potent antigen-presenting cells in the human lung and are now recognized as crucial initiators of immune responses in general. They are arranged as sentinels in a dense surveillance network inside and below the epithelium of the airways and alveoli, where they are ideally situated to...

journal_title：Expert review of respiratory medicine

authors： Blank F,von Garnier C,Obregon C,Rothen-Rutishauser B,Gehr P,Nicod L

更新日期：2008-04-01 00:00:00

abstract：:Introduction: The forced expiratory flow between 25% and 75% of forced vital capacity (FEF25-75) is a spirometry parameter that may be useful in many clinical settings. Values <65% of predicted have been defined as abnormal.Areas covered: The current report discusses the clinical value of FEF25-75 in different setting...

journal_title：Expert review of respiratory medicine

authors： Ciprandi G,Cirillo I

更新日期：2019-12-01 00:00:00

abstract：INTRODUCTION:The use of beta-blockers in chronic obstructive pulmonary disease (COPD) is controversial, primarily due to concerns that they may worsen lung function and attenuate bronchodilator response. Areas covered: This review summarizes the reasons for and against the use of beta-blockers in COPD by evaluating the...

journal_title：Expert review of respiratory medicine

authors： Leitao Filho FS,Alotaibi NM,Yamasaki K,Ngan DA,Sin DD

更新日期：2018-02-01 00:00:00

abstract：:Methicillin-resistant Staphylococcus aureus (MRSA) has become one of the leading etiologies of nosocomial pneumonia as a result of an increase in staphylococcal infections caused by methicillin-resistant strains paired with extended ventilatory support of critically, and often, chronically ill patients. The prevalence...

journal_title：Expert review of respiratory medicine

authors： Woods C,Colice G

更新日期：2014-10-01 00:00:00

abstract：:Conducting clinical trials on pulmonary hypertension in the US and Western Europe has become increasingly difficult and costly because of many challenges. These include a limited patient population that makes recruitment difficult. Recruiting internationally has helped, but can add variability. The choice of end point...

journal_title：Expert review of respiratory medicine

authors： Hill NS,Roberts K,Preston I

更新日期：2015-10-01 00:00:00

abstract：:Patients suffering from COPD not controlled by a single bronchodilator should be given two bronchodilators with different mechanisms of action. Addition of a LABA to a LAMA induces a larger bronchodilation than that obtained with the LAMA as monotherapy and also improves many patient-reported outcomes. Since the clini...

journal_title：Expert review of respiratory medicine

authors： Calzetta L,Ciaprini C,Puxeddu E,Cazzola M

更新日期：2016-04-01 00:00:00

abstract：:Introduction: Idiopathic pulmonary fibrosis (IPF), the most common of the idiopathic interstitial pneumonias, is a disease with a poor prognosis, and a highly heterogeneous and unpredictable clinical course. While most patients experience a relatively slow clinical, functional and radiological deterioration, a signifi...

journal_title：Expert review of respiratory medicine

authors： Biondini D,Balestro E,Sverzellati N,Cocconcelli E,Bernardinello N,Ryerson CJ,Spagnolo P

更新日期：2020-04-01 00:00:00

abstract：:Asthma is often associated with various comorbidities. The most frequently reported asthma comorbid conditions include rhinitis, sinusitis, gastroesophageal reflux disease, obstructive sleep apnea, hormonal disorders and psychopathologies. These conditions may, first: share a common pathophysiological mechanism with a...

journal_title：Expert review of respiratory medicine

authors： Boulet LP,Boulay MÈ

更新日期：2011-06-01 00:00:00

abstract：:Long-term oxygen therapy (LTOT) has been shown to reduce pulmonary hypertension and improve survival in patients with chronic obstructive pulmonary disease and resting hypoxemia (reduced arterial partial pressure of oxygen ≤55 mmHg). However, the benefit of its use for chronic pulmonary diseases other than chronic obs...

journal_title：Expert review of respiratory medicine

authors： Jindal SK,Agarwal R

更新日期：2012-12-01 00:00:00

abstract：INTRODUCTION:Non-small cell lung cancer patients harboring uncommon epidermal growth factor receptor (EGFR) mutations together account for approximately 10% of all EGFR mutations. The most common of which being G719X, S768I, L861Q, and exon 20 insertions. The clinical significance, particularly their response to EGFR t...

journal_title：Expert review of respiratory medicine

authors： Wu TH,Hsiue EH,Lee JH,Lin CC,Yang JC

更新日期：2017-01-01 00:00:00

abstract：INTRODUCTION:Idiopathic pulmonary fibrosis (IPF) is a chronic, debilitating, fibrotic lung disease leading to respiratory failure, and ultimately to death. It is characterized by marked heterogeneity regarding its clinical course. Despite significant progress in the understanding of its pathogenesis, the course of the ...

journal_title：Expert review of respiratory medicine

authors： Inchingolo R,Varone F,Sgalla G,Richeldi L

更新日期：2019-01-01 00:00:00

abstract：:Middle East respiratory syndrome coronavirus (MERS-CoV) was first recognized in 2012 and since then has resulted in cases in 23 countries in four continents. The majority of these cases were reported from the Kingdom of Saudi Arabia. The disease caused a spectrum of illness, from asymptomatic to severe and possibly fa...

journal_title：Expert review of respiratory medicine

authors： Al-Tawfiq JA,Memish ZA

更新日期：2015-06-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a very common disease all around the world and has become an increasing public health concern to the Chinese medical community. In the past decades, telehealthcare technology has become a good way to manage COPD but current evidence makes it hard to determine the effecti...

journal_title：Expert review of respiratory medicine

authors： Lao X,Zhang J,Bai C

更新日期：2013-10-01 00:00:00

abstract：INTRODUCTION:The management of infected pleural effusion is complex. Therapeutic resolution requires determining the following: appropriate antibiotic regimen, the need for pleural drainage, the optimal drainage tube size, and the need for intrapleural therapy or surgery. Areas covered: An updating of the latest advanc...

journal_title：Expert review of respiratory medicine

authors： Ferreiro L,Porcel JM,Bielsa S,Toubes ME,Álvarez-Dobaño JM,Valdés L

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVE:The aim of this pilot study was to determine the combined effect of vitamin D and omega-3 polyunsaturated fatty acid (PUFA) supplementation on airway function and inflammation in recreational athletes with exercise-induced bronchoconstriction (EIB). METHODS:Ten recreational athletes with EIB participated in ...

journal_title：Expert review of respiratory medicine

authors： Price OJ,Hull JH,Howatson G,Robson-Ansley P,Ansley L

更新日期：2015-06-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease characterized by persistent airflow limitation. It is the third leading cause of death worldwide, and there are currently no curative strategies for this disease. Many factors contribute to COPD susceptibility, progression and exacerbations. These...

journal_title：Expert review of respiratory medicine

authors： Goh F,Shaw JG,Savarimuthu Francis SM,Vaughan A,Morrison L,Relan V,Marshall HM,Dent AG,O'Hare PE,Hsiao A,Bowman RV,Fong KM,Yang IA

更新日期：2013-12-01 00:00:00

abstract：:The hallmarks of allergic bronchial asthma arise from chronic airway inflammation. Thus, elucidating the mechanisms regulating the maintenance of this chronic inflammatory response is key to understanding asthma pathogenesis. To date, it is not clear whether a predominance of proinflammatory factors or a reduced capac...

journal_title：Expert review of respiratory medicine

authors： Lunding L,Schröder A,Wegmann M

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:Pleural disease encompasses a large range of conditions, is a common presentation to the acute medical take and often requires comprehensive investigation and treatment. Ultrasound is well recognised as a useful investigative tool in pleural disease especially in the field of pleural effusion, pleural thic...

journal_title：Expert review of respiratory medicine

authors： Mercer RM,Psallidas I,Rahman NM

更新日期：2017-04-01 00:00:00

abstract：:The need for novel and more effective approaches to tobacco control is unquestionable. The electronic cigarette is a battery-powered electronic nicotine delivery system that looks very similar to a conventional cigarette and is capable of emulating smoking, but without the combustion products accountable for smoking's...

journal_title：Expert review of respiratory medicine

authors： Caponnetto P,Campagna D,Papale G,Russo C,Polosa R

更新日期：2012-02-01 00:00:00

abstract：:Lung transplantation is the only effective treatment for many advanced lung diseases. However, long-term survival after transplantation remains relatively poor, thus limiting the application of lung transplantation to patients with end-stage disease only. Acute and chronic rejection is the main reason for allograft fa...

journal_title：Expert review of respiratory medicine

authors： Garantziotis S,Palmer SM

更新日期：2007-10-01 00:00:00

abstract：:Introduction: Acute respiratory distress syndrome (ARDS) is a severe form of acute lung injury common in critically ill patients and characterized by significant morbidity and mortality. It frequently manifests long-lasting effects beyond hospitalization, from cognitive impairment to physical weakness.Areas covered: S...

journal_title：Expert review of respiratory medicine

authors： Mart MF,Ware LB

更新日期：2020-06-01 00:00:00