Abstract:
:It has been suggested that excessive exposure of children to the dynamic and highly salient audio-visual stimuli conveyed by electronic media may induce attention-related deficits in adulthood. This study was designed to evaluate this hypothesis in a controlled animal model setup. Building on their natural responsiveness to odors, we exposed juvenile rats for 1 h daily to a dynamic series of interchanging, highly salient odors, while controls were exposed to a non-changing mixture of these odors. Upon reaching adulthood, we tested the attentional capacity of the rats and measured their brain-derived neurotrophic factor (BDNF) levels as a proxy of neuronal plasticity. As compared with controls, rats exposed to the dynamic stimulation showed no attentional deficits under baseline task conditions, but their performance was dramatically impaired when an auditory distractor was introduced in the task. In addition, BDNF levels in the dorsal striatum of these rats were significantly increased relative to controls. These findings provide first empirical evidence that a continuous exposure to dynamic, highly salient stimuli has long-term effects on attentional functions later in life, and that these effects may have neural correlates in the dorsal striatum.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Hadas I,Gal R,Bokovza L,Meiran N,Feifel D,Zangen Adoi
10.1038/srep21129subject
Has Abstractpub_date
2016-02-17 00:00:00pages
21129issn
2045-2322pii
srep21129journal_volume
6pub_type
杂志文章abstract::Despite their interest and threat status, the number of whales in world's oceans remains highly uncertain. Whales detection is normally carried out from costly sighting surveys, acoustic surveys or through high-resolution images. Since deep convolutional neural networks (CNNs) are achieving great performance in severa...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-50795-9
更新日期:2019-10-03 00:00:00
abstract::We report on angle-dependent measurements of the sheet resistances and Hall coefficients of electron liquids in SmTiO3/SrTiO3/SmTiO3 quantum well structures, which were grown by molecular beam epitaxy on (001) DyScO3. We compare their transport properties with those of similar structures grown on LSAT [(La0.3Sr0.7)(Al...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-10841-w
更新日期:2017-09-04 00:00:00
abstract::We propose and demonstrate a type of a broadband half-wave plate that operates in the reflective mode. It consists of a metal grating embedded in a dielectric slab and placed on top of a grounded metal surface. We theoretically show that owing to the optical feedback effect which originates from the wave reflections a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-09561-y
更新日期:2017-08-22 00:00:00
abstract::Pain is a harmful sensation that arises from noxious stimuli. Transient receptor potential ankyrin 1 (TRPA1) is one target for studying pain mechanisms. TRPA1 is activated by various stimuli such as noxious cold, pungent natural products and environmental irritants. Since TRPA1 is an attractive target for pain therapy...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep37460
更新日期:2016-11-22 00:00:00
abstract::Psoriasis is a chronic inflammatory skin disease characterized by abnormal keratinocyte proliferation and terminal differentiation. Interleukin-22 (IL-22) and the transcription factor Stat3 play pivotal roles in the pathogenesis of psoriasis. CD147 is a transmembrane glycosylation protein that belongs to the immunoglo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep44172
更新日期:2017-03-08 00:00:00
abstract::Hallmarks of Retinitis Pigmentosa (RP), a family of genetic diseases, are a typical rod-cone-degeneration with initial night blindness and loss of peripheral vision, followed by decreased daylight sight and progressive visual acuity loss up to legal blindness. Great heterogeneity in nature and function of mutated gene...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-06045-x
更新日期:2017-07-18 00:00:00
abstract::The diversity of DNA sequencing methods and algorithms for genome assemblies presents scientists with a bewildering array of choices. Here, we construct and compare eight candidate assemblies combining overlapping shotgun read data, mate-pair and Chicago libraries and four different genome assemblers to produce a high...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-19430-x
更新日期:2018-01-24 00:00:00
abstract::Lon is an essential, multitasking AAA(+) protease regulating many cellular processes in species across all kingdoms of life. Altered expression levels of the human mitochondrial Lon protease (hLon) are linked to serious diseases including myopathies, paraplegia, and cancer. Here, we present the first 3D structure of f...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep33631
更新日期:2016-09-16 00:00:00
abstract::The wheat avenin-like proteins (ALP) are considered atypical gluten constituents and have shown positive effects on dough properties revealed using a transgenic approach. However, to date the genetic architecture of ALP genes is unclear, making it impossible to be utilized in wheat breeding. In the current study, thre...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep30692
更新日期:2016-08-09 00:00:00
abstract::We propose a new approach to the generation of acoustic frequency combs (AFC)-signals with spectra containing equidistant coherent peaks. AFCs are essential for a number of sensing and measurement applications, where the established technology of optical frequency combs suffers from fundamental physical limitations. O...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-79567-6
更新日期:2021-01-08 00:00:00
abstract::Vitamin D is important in multiple health conditions. Vitamin D deficiency is prevalent globally even with exposure to adequate sunlight. Reduction in provitamin D3 (7-dehydrocholesterol, 7-DHC) is an important cause of vitamin D3 deficiency. Vitamin supplementation, food fortification, and use of probiotics are some ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-55699-2
更新日期:2019-12-17 00:00:00
abstract::Pancreas development requires restrained Hedgehog (Hh) signaling activation. While deregulated Hh signaling in the pancreatic mesenchyme has been long suggested to be detrimental for proper organogenesis, this association was not directly shown. Here, we analyzed the contribution of mesenchymal Hh signaling to pancrea...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep38008
更新日期:2016-11-28 00:00:00
abstract::Network robustness represents the ability of networks to withstand failures and perturbations. In social networks, maintenance of individual activities, also called persistence, is significant towards understanding robustness. Previous works usually consider persistence on pre-generated network structures; while in so...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep42956
更新日期:2017-02-21 00:00:00
abstract::Although it is known that malaria parasites proliferate in the midgut of mosquito vector, their detailed behaviors, from gamete maturation to formation of next generation sporozoite, have not been fully understood at cellular or molecular level. This is mainly attributed to technical difficulties of dissection and who...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-38529-3
更新日期:2019-02-11 00:00:00
abstract::The pathological skin phenotype caused by hyperglycemia is an important indicator for the progress of diabetes mellitus. An early detection of diabetes assures an early intervention to regulate the carbohydrate metabolism. In this publication a non-invasive detection principle based on the measurement of complex scatt...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-06034-0
更新日期:2017-07-19 00:00:00
abstract::A previous study identified 3 nonsynonymous and 6 synonymous mutations in the entire mosquito sodium channel of Culex quinquefasciatus, the prevalence of which were strongly correlated with levels of resistance and increased dramatically following insecticide selection. However, it is unclear whether this is unique to...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep00781
更新日期:2012-01-01 00:00:00
abstract::Type 2 diabetes mellitus (T2DM) can cause multidimensional cognitive deficits, among which working memory (WM) is usually involved at an early stage. However, the neural substrates underlying impaired WM in T2DM patients are still unclear. To clarify this issue, we utilized functional magnetic resonance imaging (fMRI)...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep23767
更新日期:2016-03-29 00:00:00
abstract::Sediment accretion (burial) and nutrient enrichment occur concurrently in lacustrine wetlands, but the role of these two aspects of sedimentation on macrophyte performance has rarely been examined. Here, we investigated the concurrent effects of sediment accretion and nutrient enrichment on the growth and propagation ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep39963
更新日期:2017-01-05 00:00:00
abstract:UNLABELLED:We investigated hybrid inorganic-organic solar cells combining monocrystalline n-type silicon (n-Si) and a highly conductive polymer poly(3,4-ethylenedioxythiophene)-poly(styrene sulfonate) ( PEDOT:PSS). The build-in potential, photo- and dark saturation current at this hybrid interface are monitored for va...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep13008
更新日期:2015-08-17 00:00:00
abstract::Identifying the vital nodes in networks is of great significance for understanding the function of nodes and the nature of networks. Many centrality indices, such as betweenness centrality (BC), eccentricity centrality (EC), closeness centricity (CC), structural holes (SH), degree centrality (DC), PageRank (PR) and ei...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-59616-w
更新日期:2020-02-14 00:00:00
abstract::An analysis of Candida albicans ABC transporters identified conserved related α-helical sequence motifs immediately C-terminal of each Walker A sequence. Despite the occurrence of these motifs in ABC subfamilies of other yeasts and higher eukaryotes, their roles in protein function remained unexplored. In this study w...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep27132
更新日期:2016-06-02 00:00:00
abstract::Silica columns from PCR purification and gel extraction kits are widely used in laboratories worldwide to assist in gene cloning. However, the use of these columns can generate plastic waste that has an environmental impact due to their one-off design and massive consumption. Thus, it is important to develop a novel m...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-30316-w
更新日期:2018-08-27 00:00:00
abstract::Dinosaurs thrived and reproduced in various regions worldwide, including the Arctic. In order to understand their nesting in diverse or extreme environments, the relationships between nests, nesting environments, and incubation methods in extant archosaurs were investigated. Statistical analyses reveal that species of...
journal_title:Scientific reports
pub_type: 历史文章,杂志文章
doi:10.1038/s41598-018-21386-x
更新日期:2018-03-15 00:00:00
abstract::The study explored differences in the steroidogenic pathway between obese and nonobese women with polycystic ovary syndrome (PCOS) using liquid chromatography-tandem mass spectrometry (LC-MS/MS). 1044 women with PCOS (including 350 lean, 312 overweight and 382 obese) and 366 control women without PCOS (including 203 l...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-14534-2
更新日期:2017-10-26 00:00:00
abstract::As a universal quantum character of quantum correlation, the freezing phenomenon is researched by geometry and quantum discord methods, respectively. In this paper, the properties of Rènyi discord is studied for two independent Dimer System coupled to two correlated Fermi-spin environments under the non-Markovian cond...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-51206-9
更新日期:2019-10-14 00:00:00
abstract::The spine flexibility creates one of the most significant challenges to proper positioning in radiation therapy of head and neck cancers. Even though existing immobilization techniques can reduce the positioning uncertainty, residual errors (2-3 mm along the cervical spine) cannot be mitigated by single translation-ba...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-50797-7
更新日期:2019-10-07 00:00:00
abstract::Previous studies have shown that it is possible to nutritionally program gilthead seabream offspring through fish oil (FO) replacement by vegetable oils (VO) in the broodstock diet, to improve their ability to grow fast when fed low fish meal (FM) and FO diets during grow-out phase. However, in those studies broodstoc...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-72166-5
更新日期:2020-09-23 00:00:00
abstract::Autosomal dominant North Carolina macular dystrophy (NCMD) is believed to represent a failure of macular development. The disorder has been linked to two loci, MCDR1 (chromosome 6q16) and MCDR3 (chromosome 5p15-p13). Recently, non-coding variants upstream of PRDM13 (MCDR1) and a duplication including IRX1 (MCDR3) have...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-06387-6
更新日期:2017-08-08 00:00:00
abstract::In the present work, we demonstrated the biosynthesis of silver nanoparticles (AgNPs) by highly stable, economic and eco-friendly method using leaf extract of Terminalia arjuna (T. arjuna) and employing as a catalyst for the degradation of methyl orange (MO), methylene blue (MB), congo red (CR) and 4- nitrophenol (4-N...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-66851-8
更新日期:2020-06-15 00:00:00
abstract::Friction is a major inhibitor in almost every mechanical system. Enlightened by the Leidenfrost effect - a droplet can be levitated by its own vapor layer on a sufficiently hot surface - we demonstrate for the first time that a small cart can also be levitated by Leidenfrost vapor. The levitated cart can carry certain...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep00797
更新日期:2012-01-01 00:00:00