Spectral variation of fluorescence lifetime near single metal nanoparticles.

Abstract:

:We explore the spectral dependence of fluorescence enhancement and the associated lifetime modification of fluorescent molecules coupled to single metal nanoparticles. Fluorescence lifetime imaging microscopy and single-particle dark-field spectroscopy are combined to correlate the dependence of fluorescence lifetime reduction on the spectral overlap between the fluorescence emission and the localised surface plasmon (LSP) spectra of individual gold nanoparticles. A maximum lifetime reduction is observed when the fluorescence and LSP resonances coincide, with good agreement provided by numerical simulations. The explicit comparison between experiment and simulation, that we obtain, offers an insight into the spectral engineering of LSP mediated fluorescence and may lead to optimized application in sensing and biomedicine.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Li J,Krasavin AV,Webster L,Segovia P,Zayats AV,Richards D

doi

10.1038/srep21349

subject

Has Abstract

pub_date

2016-02-15 00:00:00

pages

21349

issn

2045-2322

pii

srep21349

journal_volume

6

pub_type

杂志文章
  • Intra-epidemic evolutionary dynamics of a Dengue virus type 1 population reveal mutant spectra that correlate with disease transmission.

    abstract::Dengue virus (DENV) is currently the most prevalent mosquito-borne viral pathogen. DENVs naturally exist as highly heterogeneous populations. Even though the descriptions on DENV diversity are plentiful, only a few studies have narrated the dynamics of intra-epidemic virus diversity at a fine scale. Such accounts are ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep22592

    authors: Hapuarachchi HC,Koo C,Kek R,Xu H,Lai YL,Liu L,Kok SY,Shi Y,Chuen RL,Lee KS,Maurer-Stroh S,Ng LC

    更新日期:2016-03-04 00:00:00

  • Surface enhanced Raman spectroscopy of Chlamydia trachomatis and Neisseria gonorrhoeae for diagnostics, and extra-cellular metabolomics and biochemical monitoring.

    abstract::SERS spectra excited at 785 nm of the bacteria Chlamydia trahomatis (elementary bodies, EB) and Neisseria gonorrheoae, the causative pathogens for the two most common sexually transmitted diseases (STD), chlamydia and gonorrhea, respectively, are reported. Although both are Gram-negative bacteria, the SERS signatures ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-23562-5

    authors: Chen Y,Premasiri WR,Ziegler LD

    更新日期:2018-03-26 00:00:00

  • Antibody production by in vivo RNA transfection.

    abstract::Monoclonal antibodies have a variety of applications in research and medicine. Here, we report development of a new method for production of monoclonal antibodies. Our method relies on in vivo RNA transfection rather than peptide vaccination. We took advantage of RNA transcripts complexed with DOTMA and DOPE lipids to...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-11399-3

    authors: Romani B,Kavyanifard A,Allahbakhshi E

    更新日期:2017-09-07 00:00:00

  • Developing and diagnosing climate change indicators of regional aerosol optical properties.

    abstract::Given the importance of aerosol particles to radiative transfer via aerosol-radiation interactions, a methodology for tracking and diagnosing causes of temporal changes in regional-scale aerosol populations is illustrated. The aerosol optical properties tracked include estimates of total columnar burden (aerosol optic...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-18402-x

    authors: Sullivan RC,Levy RC,da Silva AM,Pryor SC

    更新日期:2017-12-22 00:00:00

  • Production of FAME biodiesel in E. coli by direct methylation with an insect enzyme.

    abstract::Most biodiesel currently in use consists of fatty acid methyl esters (FAMEs) produced by transesterification of plant oils with methanol. To reduce competition with food supplies, it would be desirable to directly produce biodiesel in microorganisms. To date, the most effective pathway for the production of biodiesel ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep24239

    authors: Sherkhanov S,Korman TP,Clarke SG,Bowie JU

    更新日期:2016-04-07 00:00:00

  • Lossless Three-Dimensional Parallelization in Digitally Scanned Light-Sheet Fluorescence Microscopy.

    abstract::We introduce a concept that enables parallelized three-dimensional imaging throughout large volumes with isotropic 300-350 nm resolution. By staggering high aspect ratio illumination beams laterally and axially within the depth of focus of a digitally scanned light-sheet fluorescence microscope (LSFM), multiple image ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-08113-8

    authors: Dean KM,Fiolka R

    更新日期:2017-08-24 00:00:00

  • Hearing impairment and associated morphological changes in pituitary adenylate cyclase activating polypeptide (PACAP)-deficient mice.

    abstract::Pituitary adenylate cyclase activating polypeptide (PACAP) is a regulatory and cytoprotective neuropeptide, its deficiency implies accelerated aging in mice. It is present in the auditory system having antiapoptotic effects. Expression of Ca2+-binding proteins and its PAC1 receptor differs in the inner ear of PACAP-de...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-50775-z

    authors: Fulop DB,Humli V,Szepesy J,Ott V,Reglodi D,Gaszner B,Nemeth A,Szirmai A,Tamas L,Hashimoto H,Zelles T,Tamas A

    更新日期:2019-10-10 00:00:00

  • Accumulation of magnetite by flotation on bubbles during decompression of silicate magma.

    abstract::Magnetite (Fe3O4) is an iron ore mineral that is globally mined especially for steel production. It is denser (5.15 g/cm3) than Earth's crust (~2.7 g/cm3) and is expected to accumulate at the bottom of melt-rich magma reservoirs. However, recent studies revealed heterogeneous fluid bubble nucleation on oxide minerals ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-40376-1

    authors: Knipping JL,Webster JD,Simon AC,Holtz F

    更新日期:2019-03-07 00:00:00

  • Microbial communities and arsenic biogeochemistry at the outflow of an alkaline sulfide-rich hot spring.

    abstract::Alkaline sulfide-rich hot springs provide a unique environment for microbial community and arsenic (As) biogeochemistry. In this study, a representative alkaline sulfide-rich hot spring, Zimeiquan in the Tengchong geothermal area, was chosen to study arsenic geochemistry and microbial community using Illumina MiSeq se...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep25262

    authors: Jiang Z,Li P,Van Nostrand JD,Zhang P,Zhou J,Wang Y,Dai X,Zhang R,Jiang D,Wang Y

    更新日期:2016-04-29 00:00:00

  • Concurrent targeting of BMI1 and CDK4/6 abrogates tumor growth in vitro and in vivo.

    abstract::Despite recent advances in cancer management and therapy, resistance to cytotoxic medications remains a major clinical challenge; hence, combination-based anti-cancer treatment regimens are currently gaining momentum. PTC-209 reduced BMI1 protein expression, while palbociclib inhibited CDK4, Rb, and pRbSer795 protein ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-50140-0

    authors: Elango R,Vishnubalaji R,Manikandan M,Binhamdan SI,Siyal AA,Alshawakir YA,Alfayez M,Aldahmash A,Alajez NM

    更新日期:2019-09-23 00:00:00

  • 24-hour-restraint stress induces long-term depressive-like phenotypes in mice.

    abstract::There is an increasing risk of mental disorders, such as acute stress disorder (ASD), post-traumatic stress disorder (PTSD) and depression among survivors who were trapped in rubble during earthquake. Such long-term impaction of a single acute restraint stress has not been extensively explored. In this study, we subje...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep32935

    authors: Chu X,Zhou Y,Hu Z,Lou J,Song W,Li J,Liang X,Chen C,Wang S,Yang B,Chen L,Zhang X,Song J,Dong Y,Chen S,He L,Xie Q,Chen X,Li W

    更新日期:2016-09-09 00:00:00

  • Paradoxical puborectalis syndrome on diffusion-weighted imaging: a retrospective study of 72 cases.

    abstract::This study aimed to evaluate the application value of diffusion-weighted imaging (DWI) for assessing paradoxical puborectalis syndrome (PPS) in patients with obstructive defecation syndrome (ODS). The medical records of 72 ODS patients who underwent magnetic resonance (MR)-DWI and MR-defecography were retrospectively ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-03127-8

    authors: Liu G,Cui Z,Dai Y,Yao Q,Xu J,Wu G

    更新日期:2017-06-07 00:00:00

  • Expression of the human antimicrobial peptide β-defensin-1 is repressed by the EGFR-ERK-MYC axis in colonic epithelial cells.

    abstract::The human β-defensin-1 (HBD1) is an antimicrobial peptide constitutively expressed by epithelial cells at mucosal surfaces. In addition to its microbicidal properties, the loss of HBD1 expression in several cancers suggests that it may also have an anti-tumor activity. Here, we investigated the link between HBD1 expre...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-36387-z

    authors: Bonamy C,Sechet E,Amiot A,Alam A,Mourez M,Fraisse L,Sansonetti PJ,Sperandio B

    更新日期:2018-12-21 00:00:00

  • Wild specimens of sand fly phlebotomine Lutzomyia evansi, vector of leishmaniasis, show high abundance of Methylobacterium and natural carriage of Wolbachia and Cardinium types in the midgut microbiome.

    abstract::Phlebotomine sand flies are remarkable vectors of several etiologic agents (virus, bacterial, trypanosomatid Leishmania), posing a heavy health burden for human populations mainly located at developing countries. Their intestinal microbiota is involved in a wide range of biological and physiological processes, and cou...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-53769-z

    authors: Vivero RJ,Villegas-Plazas M,Cadavid-Restrepo GE,Herrera CXM,Uribe SI,Junca H

    更新日期:2019-11-28 00:00:00

  • Dynamical transitions during the collapse of inertial holes.

    abstract::At the center of a collapsing hole lies a singularity, a point of infinite curvature where the governing equations break down. It is a topic of fundamental physical interest to clarify the dynamics of fluids approaching such singularities. Here, we use scaling arguments supported by high-fidelity simulations to analyz...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-50956-w

    authors: Lu J,Corvalan CM

    更新日期:2019-10-10 00:00:00

  • Analysis of influencing factors on soil Zn content using generalized additive model.

    abstract::Soil zinc (Zn) plays a crucial role in plant growth, but excessive accumulation in the environment may lead to air, water and soil pollution. It is affected by various chemical, environmental and spatial factors. Therefore, it is important to identify the factors influencing Zn content in the landscape. The main motiv...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-33745-9

    authors: Jiang Y,Gao WW,Zhao JL,Chen Q,Liang D,Xu C,Huang LS,Ruan LM

    更新日期:2018-10-22 00:00:00

  • System-specific periodicity in quantitative real-time polymerase chain reaction data questions threshold-based quantitation.

    abstract::Real-time quantitative polymerase chain reaction (qPCR) data are found to display periodic patterns in the fluorescence intensity as a function of sample number for fixed cycle number. This behavior is seen for technical replicate datasets recorded on several different commercial instruments; it occurs in the baseline...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep38951

    authors: Spiess AN,Rödiger S,Burdukiewicz M,Volksdorf T,Tellinghuisen J

    更新日期:2016-12-13 00:00:00

  • Using nanoBRET and CRISPR/Cas9 to monitor proximity to a genome-edited protein in real-time.

    abstract::Bioluminescence resonance energy transfer (BRET) has been a vital tool for understanding G protein-coupled receptor (GPCR) function. It has been used to investigate GPCR-protein and/or -ligand interactions as well as GPCR oligomerisation. However the utility of BRET is limited by the requirement that the fusion protei...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-03486-2

    authors: White CW,Vanyai HK,See HB,Johnstone EKM,Pfleger KDG

    更新日期:2017-06-09 00:00:00

  • FGF23 is synthesised locally by renal tubules and activates injury-primed fibroblasts.

    abstract::In kidney disease, higher circulating levels of the mineral-regulating hormone fibroblast growth factor (FGF)-23 are predictive of disease progression but direct pathogenic effects on the kidney are unknown. We sought evidence of local renal synthesis in response to unilateral ureteric obstruction in the mouse, and pr...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-02709-w

    authors: Smith ER,Tan SJ,Holt SG,Hewitson TD

    更新日期:2017-06-13 00:00:00

  • Transmission patterns of HIV-1 non-R5 strains in Poland.

    abstract::HIV-1 env sequencing enables predictions of viral coreceptor tropism and phylogenetic investigations of transmission events. The aim of the study was to estimate the contribution of non-R5 strains to the viral spread in Poland. Partial proviral env sequences were retrieved from baseline blood samples of patients with ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-41407-7

    authors: Smoleń-Dzirba J,Rosińska M,Kruszyński P,Janiec J,Cycoń M,Bratosiewicz-Wąsik J,Beniowski M,Bociąga-Jasik M,Jabłonowska E,Szetela B,Wąsik TJ

    更新日期:2019-03-21 00:00:00

  • Basolateral amygdala rapid glutamate release encodes an outcome-specific representation vital for reward-predictive cues to selectively invigorate reward-seeking actions.

    abstract::Environmental stimuli have the ability to generate specific representations of the rewards they predict and in so doing alter the selection and performance of reward-seeking actions. The basolateral amygdala participates in this process, but precisely how is unknown. To rectify this, we monitored, in near-real time, b...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep12511

    authors: Malvaez M,Greenfield VY,Wang AS,Yorita AM,Feng L,Linker KE,Monbouquette HG,Wassum KM

    更新日期:2015-07-27 00:00:00

  • Specific binding of Bacillus thuringiensis Cry1Ea toxin, and Cry1Ac and Cry1Fa competition analyses in Anticarsia gemmatalis and Chrysodeixis includens.

    abstract::Anticarsia gemmatalis (velvetbean caterpillar) and Chrysodeixis includens (soybean looper) are two important defoliation pests of soybeans. In the present study, we have investigated the susceptibility and brush border membrane-binding properties of both species to Bacillus thuringiensis Cry1Ea toxin. Bioassays perfor...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-54850-3

    authors: Bel Y,Zack M,Narva K,Escriche B

    更新日期:2019-12-03 00:00:00

  • Fragment-based screening identifies inhibitors of ATPase activity and of hexamer formation of Cagα from the Helicobacter pylori type IV secretion system.

    abstract::Type IV secretion systems are multiprotein complexes that mediate the translocation of macromolecules across the bacterial cell envelope. In Helicobacter pylori a type IV secretion system encoded by the cag pathogenicity island encodes 27 proteins and most are essential for virulence. We here present the identificatio...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-42876-6

    authors: Arya T,Oudouhou F,Casu B,Bessette B,Sygusch J,Baron C

    更新日期:2019-04-24 00:00:00

  • Non-invasive imaging of engineered human tumors in the living chicken embryo.

    abstract::The growing interest in engineered tumor models prompted us to devise a method for the non-invasive assessment of such models. Here, we report on bioluminescence imaging (BLI) for the assessment of engineered tumor models in the fertilized chicken egg, i.e, chick chorioallantoic membrane (CAM) assay. One prostate canc...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-04572-1

    authors: Jefferies B,Lenze F,Sathe A,Truong N,Anton M,von Eisenhart-Rothe R,Nawroth R,Mayer-Kuckuk P

    更新日期:2017-07-10 00:00:00

  • Clinical impact of irreversible electroporation ablation for unresectable hilar cholangiocarcinoma.

    abstract::Irreversible electroporation (IRE) is a non-thermal ablation modality that has been shown to be safe and effective in its application to tumors that are close to risky areas. This study aims to assess the safety and efficacy of IRE for unresectable hilar cholangiocarcinoma. Nine patients from two medical centers in As...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-67772-2

    authors: Hsiao CY,Yang PC,Li X,Huang KW

    更新日期:2020-07-02 00:00:00

  • A prediction model of outcome of SARS-CoV-2 pneumonia based on laboratory findings.

    abstract::The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in thousands of deaths in the world. Information about prediction model of prognosis of SARS-CoV-2 infection is scarce. We used machine learning for processing laboratory findings of 110 patients with SARS-CoV-2 pneumonia (including 51 non-s...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-71114-7

    authors: Wu G,Zhou S,Wang Y,Lv W,Wang S,Wang T,Li X

    更新日期:2020-08-20 00:00:00

  • Identification of a New Broadly Cross-reactive Epitope within Domain III of the Duck Tembusu Virus E Protein.

    abstract::In 2010, a pathogenic flavivirus termed duck Tembusu virus (DTMUV) caused widespread outbreak of egg-drop syndrome in domesticated ducks in China. Although the glycoprotein E of DTMUV is an important structural component of the virus, the B-cell epitopes of this protein remains uncharacterized. Using phage display and...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep36288

    authors: Li C,Bai X,Meng R,Shaozhou W,Zhang Q,Hua R,Liu JH,Liu M,Zhang Y

    更新日期:2016-11-08 00:00:00

  • Overcoming evolved resistance to population-suppressing homing-based gene drives.

    abstract::The recent development of a CRISPR-Cas9-based homing system for the suppression of Anopheles gambiae is encouraging; however, with current designs, the slow emergence of homing-resistant alleles is expected to result in suppressed populations rapidly rebounding, as homing-resistant alleles have a significant fitness a...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-02744-7

    authors: Marshall JM,Buchman A,Sánchez C HM,Akbari OS

    更新日期:2017-06-19 00:00:00

  • Extracellular vesicles from T cells overexpress miR-146b-5p in HIV-1 infection and repress endothelial activation.

    abstract::Human immunodeficiency virus type 1 (HIV-1) infection promotes a generalized activation of host responses that involves not only CD4 T cells, but also cells of the microenvironment, which are not directly infected, such as endothelial cells. The mechanisms triggering HIV-1-associated vascular alterations remain poorly...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-44743-w

    authors: Balducci E,Leroyer AS,Lacroix R,Robert S,Todorova D,Simoncini S,Lyonnet L,Chareyre C,Zaegel-Faucher O,Micallef J,Poizot-Martin I,Roll P,Dignat-George F

    更新日期:2019-07-16 00:00:00

  • Simple Risk Score for Prediction of Early Recurrence of Hepatocellular Carcinoma within the Milan Criteria after Orthotopic Liver Transplantation.

    abstract::Ten to twenty percent of the hepatocellular carcinoma (HCC) patients fulfilling the Milan criteria (MC) recurred within three years after orthotopic liver transplantation (OLT). We therefore utilize a training cohort to develop an improved prognostic model for predicting the recurrence in these patients. By univariate...

    journal_title:Scientific reports

    pub_type: 临床试验,杂志文章

    doi:10.1038/srep44036

    authors: Feng J,Wu J,Zhu R,Feng D,Yu L,Zhang Y,Bu D,Li C,Zhou Y,Si L,Liu Y,Liang Z,Xu J,Wu T

    更新日期:2017-03-09 00:00:00