Determination and correction of persistent biases in quantum annealers.

Abstract:

:Calibration of quantum computers is essential to the effective utilisation of their quantum resources. Specifically, the performance of quantum annealers is likely to be significantly impaired by noise in their programmable parameters, effectively misspecification of the computational problem to be solved, often resulting in spurious suboptimal solutions. We developed a strategy to determine and correct persistent, systematic biases between the actual values of the programmable parameters and their user-specified values. We applied the recalibration strategy to two D-Wave Two quantum annealers, one at NASA Ames Research Center in Moffett Field, California, and another at D-Wave Systems in Burnaby, Canada. We show that the recalibration procedure not only reduces the magnitudes of the biases in the programmable parameters but also enhances the performance of the device on a set of random benchmark instances.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Perdomo-Ortiz A,O'Gorman B,Fluegemann J,Biswas R,Smelyanskiy VN

doi

10.1038/srep18628

subject

Has Abstract

pub_date

2016-01-19 00:00:00

pages

18628

issn

2045-2322

pii

srep18628

journal_volume

6

pub_type

杂志文章
  • Reconstruction of non-error magnetic hologram data by magnetic assist recording.

    abstract::Hologram memory is expected to be the next-generation of optical data storage technology. Bismuth-substituted yttrium iron garnet is typically used for rewritable magnetic hologram media. The diffraction efficiency of magnetic holography depends on the Faraday rotation angle, but the experimental diffraction efficienc...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-12442-z

    authors: Shirakashi Z,Goto T,Takagi H,Nakamura Y,Lim PB,Uchida H,Inoue M

    更新日期:2017-10-09 00:00:00

  • Precursory worldwide signatures of earthquake occurrences on Swarm satellite data.

    abstract::The study of the preparation phase of large earthquakes is essential to understand the physical processes involved, and potentially useful also to develop a future reliable short-term warning system. Here we analyse electron density and magnetic field data measured by Swarm three-satellite constellation for 4.7 years,...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-56599-1

    authors: De Santis A,Marchetti D,Pavón-Carrasco FJ,Cianchini G,Perrone L,Abbattista C,Alfonsi L,Amoruso L,Campuzano SA,Carbone M,Cesaroni C,De Franceschi G,De Santis A,Di Giovambattista R,Ippolito A,Piscini A,Sabbagh D,Soldani M

    更新日期:2019-12-30 00:00:00

  • Quantification of the boron speciation in alkali borosilicate glasses by electron energy loss spectroscopy.

    abstract::Transmission electron microscopy and related analytical techniques have been widely used to study the microstructure of different materials. However, few research works have been performed in the field of glasses, possibly due to the electron-beam irradiation damage. In this paper, we have developed a method based on ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep17526

    authors: Cheng S,Yang G,Zhao Y,Peng M,Skibsted J,Yue Y

    更新日期:2015-12-08 00:00:00

  • Repurposing Thioridazine (TDZ) as an anti-inflammatory agent.

    abstract::Nuclear factor-kB (NF-kB) is a crucial transcription factor in the signal transduction cascade of the inflammatory signaling. Activation of NF-κB depends on the phosphorylation of IκBα by IκB kinase (IKKβ) followed by subsequent ubiquitination and degradation. This leads to the nuclear translocation of the p50- p65 su...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-30763-5

    authors: Baig MS,Roy A,Saqib U,Rajpoot S,Srivastava M,Naim A,Liu D,Saluja R,Faisal SM,Pan Q,Turkowski K,Darwhekar GN,Savai R

    更新日期:2018-08-20 00:00:00

  • Soil fungal and bacterial communities in southern boreal forests of the Greater Khingan Mountains and their relationship with soil properties.

    abstract::Little is known about the relationship between soil microbial communities and soil properties in southern boreal forests. To further our knowledge about that relationship, we compared the soil samples in southern boreal forests of the Greater Khingan Mountains-the southernmost boreal forest biome in the world. The for...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-79206-0

    authors: Vuong TM,Zeng JY,Man XL

    更新日期:2020-12-16 00:00:00

  • Erratum: SWIM: a computational tool to unveiling crucial nodes in complex biological networks.

    abstract::This corrects the article DOI: 10.1038/srep44797. ...

    journal_title:Scientific reports

    pub_type: 杂志文章,已发布勘误

    doi:10.1038/srep46843

    authors: Paci P,Colombo T,Fiscon G,Gurtner A,Pavesi G,Farina L

    更新日期:2017-06-16 00:00:00

  • Dzip3 regulates developmental genes in mouse embryonic stem cells by reorganizing 3D chromatin conformation.

    abstract::In mouse embryonic stem (mES) cells, ubiquitylation of histone H2A lysine 119 represses a large number of developmental genes and maintains mES cell pluripotency. It has been suggested that a number of H2A ubiquitin ligases as well as deubiquitylases and related peptide fragments contribute to a delicate balance betwe...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep16567

    authors: Inoue D,Aihara H,Sato T,Mizusaki H,Doiguchi M,Higashi M,Imamura Y,Yoneda M,Miyanishi T,Fujii S,Okuda A,Nakagawa T,Ito T

    更新日期:2015-11-16 00:00:00

  • Protein arginylation targets alpha synuclein, facilitates normal brain health, and prevents neurodegeneration.

    abstract::Alpha synuclein (α-syn) is a central player in neurodegeneration, but the mechanisms triggering its pathology are not fully understood. Here we found that α-syn is a highly efficient substrate for arginyltransferase ATE1 and is arginylated in vivo by a novel mid-chain mechanism that targets the acidic side chains of E...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-11713-z

    authors: Wang J,Han X,Leu NA,Sterling S,Kurosaka S,Fina M,Lee VM,Dong DW,Yates JR 3rd,Kashina A

    更新日期:2017-09-12 00:00:00

  • Common variants of ARID1A and KAT2B are associated with obesity in Indian adolescents.

    abstract::Obesity involves alterations in transcriptional programs that can change in response to genetic and environmental signals through chromatin modifications. Since chromatin modifications involve different biochemical, neurological and molecular signaling pathways related to energy homeostasis, we hypothesize that geneti...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-22231-x

    authors: Giri AK,Parekatt V,Dwivedi OP,Banerjee P,Bandesh K,Prasad G,Tandon N,Bharadwaj D

    更新日期:2018-03-02 00:00:00

  • The effect of unilateral mean luminance on binocular combination in normal and amblyopic vision.

    abstract::Luminance plays a modulating role in the processes of several visual tasks, which in turn provides significant information for the understanding of visual processing. Here, using a binocular phase combination paradigm, we studied the effect of unilateral changes in mean luminance on binocular combination in both norma...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep02012

    authors: Zhou J,Jia W,Huang CB,Hess RF

    更新日期:2013-01-01 00:00:00

  • Oral CoQ10 attenuates high salt-induced hypertension by restoring neurotransmitters and cytokines in the hypothalamic paraventricular nucleus.

    abstract::High salt intake leads to an increase in some proinflammatory cytokines and neurotransmitters involved in the pathogenesis of hypertension. The purpose of this work was to know if oral administration of anti-oxidant and free-radical scavenger CoQ10 may attenuate high salt-induced hypertension via regulating neurotrans...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep30301

    authors: Gao HL,Yu XJ,Qi J,Yi QY,Jing WH,Sun WY,Cui W,Mu JJ,Yuan ZY,Zhao XF,Liu KL,Zhu GQ,Shi XL,Liu JJ,Kang YM

    更新日期:2016-07-25 00:00:00

  • Snail collaborates with EGR-1 and SP-1 to directly activate transcription of MMP 9 and ZEB1.

    abstract::The Snail transcription factor plays as a master regulator of epithelial mesenchymal transition (EMT), one of the steps of tumor metastasis. Snail enhances expressions of a lot of mesenchymal genes including the matrix degradation enzyme matrix metalloproteinases 9 (MMP9) and the EMT transcription factor zinc finger E...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-18101-7

    authors: Wu WS,You RI,Cheng CC,Lee MC,Lin TY,Hu CT

    更新日期:2017-12-19 00:00:00

  • Expansion of amphibian intronless interferons revises the paradigm for interferon evolution and functional diversity.

    abstract::Interferons (IFNs) are key cytokines identified in vertebrates and evolutionary dominance of intronless IFN genes in amniotes is a signature event in IFN evolution. For the first time, we show that the emergence and expansion of intronless IFN genes is evident in amphibians, shown by 24-37 intronless IFN genes in each...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep29072

    authors: Sang Y,Liu Q,Lee J,Ma W,McVey DS,Blecha F

    更新日期:2016-06-30 00:00:00

  • Heuristics guide the implementation of social preferences in one-shot Prisoner's Dilemma experiments.

    abstract::Cooperation in one-shot anonymous interactions is a widely documented aspect of human behaviour. Here we shed light on the motivations behind this behaviour by experimentally exploring cooperation in a one-shot continuous-strategy Prisoner's Dilemma (i.e. one-shot two-player Public Goods Game). We examine the distribu...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep06790

    authors: Capraro V,Jordan JJ,Rand DG

    更新日期:2014-10-28 00:00:00

  • Conversion of walnut tyrosinase into a catechol oxidase by site directed mutagenesis.

    abstract::Polyphenol oxidases (PPOs) comprise tyrosinases (TYRs) and catechol oxidases (COs), which catalyse the initial reactions in the biosynthesis of melanin. TYRs hydroxylate monophenolic (monophenolase activity) and oxidize diphenolic (diphenolase activity) substrates, whereas COs react only with diphenols. In order to el...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-57671-x

    authors: Panis F,Kampatsikas I,Bijelic A,Rompel A

    更新日期:2020-02-03 00:00:00

  • Diagnostic value of the γ-glutamyltransferase and alanine transaminase ratio, alpha-fetoprotein, and protein induced by vitamin K absence or antagonist II in hepatitis B virus-related hepatocellular carcinoma.

    abstract::Hepatocellular carcinoma is a common type of malignancy with a poor prognosis. Identification and utilisation of markers for monitoring and diagnosis are urgently needed. Alpha-fetoprotein (AFP) and Protein Induced by Vitamin K Absence or Antagonist-II (PIVKA-II) have been proved to be efficient biomarkers for hepatit...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-70241-5

    authors: Wang G,Lu X,Du Q,Zhang G,Wang D,Wang Q,Guo X

    更新日期:2020-08-11 00:00:00

  • Comparative transcriptomic analysis of Tibetan Gynaephora to explore the genetic basis of insect adaptation to divergent altitude environments.

    abstract::Adaptation of insects to different altitudes remain largely unknown, especially those endemic to the Tibetan Plateau (TP). Here, we generated the transcriptomes of Gynaephora menyuanensis and G. alpherakii, inhabiting different high altitudes on the TP, and used these and the previously available transcriptomic and ge...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-17051-4

    authors: Zhang QL,Zhang L,Yang XZ,Wang XT,Li XP,Wang J,Chen JY,Yuan ML

    更新日期:2017-12-05 00:00:00

  • A clinical investigation treating different types of fibroids identified by MRI-T2WI imaging with ultrasound guided high intensity focused ultrasound.

    abstract::Clinical data from 172 cases of uterine fibroids with different appearances on MRI-T2WI and accepted ultrasound guided high intensity focused ultrasound (USgHIFU) treatment were retrospectively analyzed. This study aimed to evaluate the clinical safety and efficacy of ablating different types of fibroids, classified b...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-11486-5

    authors: Zhao WP,Zhang J,Han ZY,Yao JP,Zhou X,Liang P

    更新日期:2017-09-07 00:00:00

  • Paradoxical Role of Glypican-1 in Prostate Cancer Cell and Tumor Growth.

    abstract::Recent studies suggest that glypican-1 (GPC-1) is a biomarker for prostate cancer, but there are few studies elucidating the role of GPC-1 in prostate cancer progression. We observed high expression of GPC-1 in more aggressive prostate cancer cell lines such as PC-3 and DU-145. While inhibition of GPC-1 expression in ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-47874-2

    authors: Quach ND,Kaur SP,Eggert MW,Ingram L,Ghosh D,Sheth S,Nagy T,Dawson MR,Arnold RD,Cummings BS

    更新日期:2019-08-07 00:00:00

  • PDCD4 controls the G1/S-phase transition in a telomerase-immortalized epithelial cell line and affects the expression level and translation of multiple mRNAs.

    abstract::PDCD4, the protein encoded by the tumor suppressor gene PDCD4 (programmed cell death 4) has been implicated in the control of cellular transcription and translation by modulating the activity of specific transcription factors and suppressing the translation of mRNAs with structured 5'-UTRs. Most studies of human PDCD4...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-59678-w

    authors: Haas A,Nilges BS,Leidel SA,Klempnauer KH

    更新日期:2020-02-17 00:00:00

  • Suicide Risk Associated with Experience of Violence and Impulsivity in Alcohol Dependent Patients.

    abstract::Alcohol dependence (AD) and aggression-impulsivity are both associated with increased suicide risk. There is a need to evaluate clinical tools in order to improve suicide risk assessment of AD patients. The present study consisted of 95 individuals with a diagnosis of AD, consecutively admitted for addiction treatment...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep19373

    authors: Khemiri L,Jokinen J,Runeson B,Jayaram-Lindström N

    更新日期:2016-01-19 00:00:00

  • Novel circRNA discovery in sheep shows evidence of high backsplice junction conservation.

    abstract::Circular RNAs (circRNAs) are covalently closed circular non-coding RNAs. Due to their structure, circRNAs are more stable and have longer half-lives than linear RNAs making them good candidates for disease biomarkers. Despite the scientific relevance of these molecules, the study of circRNAs in non-model organisms is ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-79781-2

    authors: Varela-Martínez E,Corsi GI,Anthon C,Gorodkin J,Jugo BM

    更新日期:2021-01-11 00:00:00

  • Molecular chaperone accumulation as a function of stress evidences adaptation to high hydrostatic pressure in the piezophilic archaeon Thermococcus barophilus.

    abstract::The accumulation of mannosyl-glycerate (MG), the salinity stress response osmolyte of Thermococcales, was investigated as a function of hydrostatic pressure in Thermococcus barophilus strain MP, a hyperthermophilic, piezophilic archaeon isolated from the Snake Pit site (MAR), which grows optimally at 40 MPa. Strain MP...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep29483

    authors: Cario A,Jebbar M,Thiel A,Kervarec N,Oger PM

    更新日期:2016-07-05 00:00:00

  • Dopamine functionalized tannic-acid-templated mesoporous silica nanoparticles as a new sorbent for the efficient removal of Cu2+ from aqueous solution.

    abstract::A simple, environmentally friendly and cost-effective nonsurfactant template method was used to synthesize tannic-acid-templated mesoporous silica nanoparticles (TMSNs), and then dopamine functionalized TMSNs (Dop-TMSNs) which was synthesized by a facile and biomimetic coating strategy, was developed as a new sorbent ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep45215

    authors: Gao J,Lei H,Han Z,Shi Q,Chen Y,Jiang Y

    更新日期:2017-03-22 00:00:00

  • High sulfur-containing carbon polysulfide polymer as a novel cathode material for lithium-sulfur battery.

    abstract::The lithium-sulfur battery, which offers a high energy density and is environmental friendly, is a promising next generation of rechargeable energy storage system. However, despite these attractive attributes, the commercialization of lithium-sulfur battery is primarily hindered by the parasitic reactions between the ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-11922-6

    authors: Zhang Y,Peng Y,Wang Y,Li J,Li H,Zeng J,Wang J,Hwang BJ,Zhao J

    更新日期:2017-09-12 00:00:00

  • Modelling of psychosocial and lifestyle predictors of peripartum depressive symptoms associated with distinct risk trajectories: a prospective cohort study.

    abstract::Perinatal depression involves interplay between individual chronic and acute disease burdens, biological and psychosocial environmental and behavioural factors. Here we explored the predictive potential of specific psycho-socio-demographic characteristics for antenatal and postpartum depression symptoms and contributi...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-30874-z

    authors: English S,Steele A,Williams A,Blacklay J,Sorinola O,Wernisch L,Grammatopoulos DK

    更新日期:2018-08-24 00:00:00

  • Species-Specific Marker Discovery in Tilapia.

    abstract::Tilapias (family Cichlidae) are of importance in aquaculture and fisheries. Hybridisation and introgression are common within tilapia genera but are difficult to analyse due to limited numbers of species-specific genetic markers. We tested the potential of double digested restriction-site associated DNA (ddRAD) sequen...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-48339-2

    authors: Syaifudin M,Bekaert M,Taggart JB,Bartie KL,Wehner S,Palaiokostas C,Khan MGQ,Selly SC,Hulata G,D'Cotta H,Baroiller JF,McAndrew BJ,Penman DJ

    更新日期:2019-09-10 00:00:00

  • Distorting temporal fine structure by phase shifting and its effects on speech intelligibility and neural phase locking.

    abstract::Envelope (E) and temporal fine structure (TFS) are important features of acoustic signals and their corresponding perceptual function has been investigated with various listening tasks. To further understand the underlying neural processing of TFS, experiments in humans and animals were conducted to demonstrate the ef...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-12975-3

    authors: Xu Y,Chen M,LaFaire P,Tan X,Richter CP

    更新日期:2017-10-17 00:00:00

  • Cortical Classification with Rhythm Entropy for Error Processing in Cocktail Party Environment Based on Scalp EEG Recording.

    abstract::Using single-trial cortical signals calculated by weighted minimum norm solution estimation (WMNE), the present study explored a feature extraction method based on rhythm entropy to classify the scalp electroencephalography (EEG) signals of error response from that of correct response during performing auditory-track ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-24535-4

    authors: Tian Y,Xu W,Yang L

    更新日期:2018-04-17 00:00:00

  • Acid-sensing ion channel 1a contributes to hippocampal LTP inducibility through multiple mechanisms.

    abstract::The exact roles of acid-sensing ion channels (ASICs) in synaptic plasticity remain elusive. Here, we address the contribution of ASIC1a to five forms of synaptic plasticity in the mouse hippocampus using an in vitro multi-electrode array recording system. We found that genetic deletion or pharmacological blockade of A...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep23350

    authors: Liu MG,Li HS,Li WG,Wu YJ,Deng SN,Huang C,Maximyuk O,Sukach V,Krishtal O,Zhu MX,Xu TL

    更新日期:2016-03-21 00:00:00