Stem cell-based gene therapy activated using magnetic hyperthermia to enhance the treatment of cancer.

abstract：:Non-invasive assay for the early stage diagnosis of methicillin resistant Staphylococcus aureus (MRSA) related pneumonia is of great clinical importance and still a great challenge. In this paper, we reported a novel kind of Au@Ag core-shell theranostic nanoparticles (NPs) conjugated with MRSA specific antibody on the...

journal_title：Biomaterials

authors： Huo D,Ding J,Cui YX,Xia LY,Li H,He J,Zhou ZY,Wang HW,Hu Y

更新日期：2014-08-01 00:00:00

abstract：:Time-dependent energetics of blood-protein adsorption are interpreted in terms of a slowly-concentrating three-dimensional interphase volume initially formed by rapid diffusion of protein molecules into an interfacial region spontaneously formed by bringing a protein solution into contact with a physical surface. This...

journal_title：Biomaterials

authors： Barnthip N,Noh H,Leibner E,Vogler EA

更新日期：2008-07-01 00:00:00

abstract：:The in vivo cellular microenvironment is regulated by a complex interplay of soluble factors and signaling molecules secreted by cells and it plays a critical role in the growth and development of normal and diseased tissues. In vitro systems that can recapitulate the microenvironment at the cellular level are needed ...

journal_title：Biomaterials

authors： Chandrasekaran S,Giang UB,King MR,DeLouise LA

更新日期：2011-10-01 00:00:00

abstract：:One of the main issues in orthopaedic implant design is the fabrication of scaffolds that closely mimic the biomechanical properties of the surrounding bone. This research reports on a multi-stage rapid prototyping technique that was successfully developed to produce porous titanium scaffolds with fully interconnected...

journal_title：Biomaterials

authors： Ryan GE,Pandit AS,Apatsidis DP

更新日期：2008-09-01 00:00:00

abstract：:Poor fixation of bone replacement implants, e.g. the artificial hip, in implantation sites with inferior bone quality and quantity may be overcome by the use of implants coated with a cultured living bone equivalent. In this study, we tested, respectively, amorphous carbonated apatite (CA)- and crystalline octacalcium...

journal_title：Biomaterials

authors： Dekker RJ,de Bruijn JD,Stigter M,Barrere F,Layrolle P,van Blitterswijk CA

更新日期：2005-09-01 00:00:00

abstract：:Crystalline carbonate- and sodium-and-carbonate-substituted hydroxyapatite (CO3HAp and NaCO3HAp) powders were prepared at room temperature via a heterogeneous reaction between Ca(OH)2/CaCO3/Na2CO3 and (NH4)2HPO4 aqueous solution using the mechanochemical hydrothermal route. X-ray diffraction, infrared spectroscopy, th...

journal_title：Biomaterials

authors： Suchanek WL,Shuk P,Byrappa K,Riman RE,TenHuisen KS,Janas VF

更新日期：2002-02-01 00:00:00

abstract：:Bone is the most frequent metastasis site for breast cancer. As well as dramatically increasing disease burden, bone metastases are also an indicator of poor prognosis. One of the main challenges in investigating bone metastasis in breast cancer is engineering in vitro models that replicate the features of in vivo bon...

journal_title：Biomaterials

authors： Han W,El Botty R,Montaudon E,Malaquin L,Deschaseaux F,Espagnolle N,Marangoni E,Cottu P,Zalcman G,Parrini MC,Assayag F,Sensebe L,Silberzan P,Vincent-Salomon A,Dutertre G,Roman-Roman S,Descroix S,Camonis J

更新日期：2020-12-24 00:00:00

abstract：:The present study has examined the efficacy of a polymer microarray platform to screen a library of polyurethanes for applications such as human skeletal progenitor cell isolation and surface modification of tissue engineering scaffolds to enhance skeletal cell growth and differentiation. Analysis of polyurethane micr...

journal_title：Biomaterials

authors： Tare RS,Khan F,Tourniaire G,Morgan SM,Bradley M,Oreffo RO

更新日期：2009-02-01 00:00:00

abstract：:Focal infections that are caused by antibiotic-resistant bacteria are becoming an ever-growing challenge to human health. To address this challenge, a pH-responsive amphiphilic polymer of polyaniline-conjugated glycol chitosan (PANI-GCS) that can self-assemble into nanoparticles (NPs) in situ is developed. The PANI-GC...

journal_title：Biomaterials

authors： Korupalli C,Huang CC,Lin WC,Pan WY,Lin PY,Wan WL,Li MJ,Chang Y,Sung HW

更新日期：2017-02-01 00:00:00

abstract：:We developed cell-free implants, comprising carbodiimide crosslinked recombinant human collagen (RHC), to enable corneal regeneration by endogenous cell recruitment, to address the worldwide shortage of donor corneas. Patients were grafted with RHC implants. Over four years, the regenerated neo-corneas were stably int...

journal_title：Biomaterials

authors： Fagerholm P,Lagali NS,Ong JA,Merrett K,Jackson WB,Polarek JW,Suuronen EJ,Liu Y,Brunette I,Griffith M

更新日期：2014-03-01 00:00:00

abstract：:We report the synthesis and characterization of dendrimer-entrapped gold nanoparticles (Au DENPs) modified by polyethylene glycol (PEG) with enhanced biocompatibility for computed tomography (CT) imaging applications. In this study, amine-terminated poly(amidoamine) dendrimers of generation 5 (G5.NH(2)) modified by PE...

journal_title：Biomaterials

authors： Peng C,Zheng L,Chen Q,Shen M,Guo R,Wang H,Cao X,Zhang G,Shi X

更新日期：2012-02-01 00:00:00

abstract：:Large-scale expansion of highly functional adult human mesenchymal stem cells (aMSCs) remains technologically challenging as aMSCs lose self renewal capacity and multipotency during traditional long-term culture and their quality/quantity declines with donor age and disease. Identification of culture conditions enabli...

journal_title：Biomaterials

authors： Ng CP,Sharif AR,Heath DE,Chow JW,Zhang CB,Chan-Park MB,Hammond PT,Chan JK,Griffith LG

更新日期：2014-04-01 00:00:00

abstract：:Chondrogenic differentiation of mesenchymal stem cells (MSCs) is critical for successful cartilage regeneration. Several methods have been developed to attempt to chondrogenic differentiation, because chondrogenic differentiated cells can form stable cartilage and induce expression of a cartilage-specific phenotype. I...

journal_title：Biomaterials

authors： Ham O,Song BW,Lee SY,Choi E,Cha MJ,Lee CY,Park JH,Kim IK,Chang W,Lim S,Lee CH,Kim S,Jang Y,Hwang KC

更新日期：2012-06-01 00:00:00

abstract：:The purpose of this study was to determine the mechanical properties and the atomistic structures of various gelatin hydrogels as a preliminary to using these in bioengineering applications. The hydrogels were investigated as neat materials and as particulate-reinforced composites both in the as-formed state and follo...

journal_title：Biomaterials

authors： Usta M,Piech DL,MacCrone RK,Hillig WB

更新日期：2003-01-01 00:00:00

abstract：:The objective of this research was to investigate whether immobilized anti-inflammatory cytokines will signal changes in the inflammatory profile of cultured monocytes. A fusion protein of recombinant human IL-1 receptor antagonist and elastin-like peptide (IL-1ra-ELP) was expressed in Escherichia coli. THP-1 human mo...

journal_title：Biomaterials

authors： Kim DH,Smith JT,Chilkoti A,Reichert WM

更新日期：2007-08-01 00:00:00

abstract：:Unhealed chronic wounds often deteriorate into multiple infection with several kinds of bacteria and excessive proteolytic wound exudate and remains one of the common healthcare issues. Here, the functional and antimicrobial hydrogel and cryogel biomaterials were prepared from glycol chitosan and a novel biodegradable...

journal_title：Biomaterials

authors： Chen TY,Wen TK,Dai NT,Hsu SH

更新日期：2020-12-16 00:00:00

abstract：:Nanoparticles formulated from biodegradable polymers such as poly(lactic acid) (PLA) and poly(lactide-co-glycolide) (PLGA) are being extensively investigated as non-viral gene delivery systems due to their controlled release characteristics and biocompatibility. PLGA nanoparticles for DNA delivery are mainly formulate...

journal_title：Biomaterials

authors： Ravi Kumar MN,Bakowsky U,Lehr CM

更新日期：2004-05-01 00:00:00

abstract：:To enable the synthesis of hydrogels containing microporosity, a family of pore generating additives (porogens) were synthesized from poly(ethylene glycols) (PEGs) with different molecular weights using naphthyl acetic acid. The products formed were characterized by UV-vis, differential scanning calorimetry and soluti...

journal_title：Biomaterials

authors： Badiger MV,McNeill ME,Graham NB

更新日期：1993-11-01 00:00:00

abstract：:Alginate hydrogels are used extensively in cell encapsulation, cell transplantation, and tissue engineering applications. Alginates possess many favorable properties required in biomaterials, but are unable to specifically interact with mammalian cells. We have therefore covalently modified alginate polysaccharides wi...

journal_title：Biomaterials

authors： Rowley JA,Madlambayan G,Mooney DJ

更新日期：1999-01-01 00:00:00

abstract：:This study was designed to explore the feasibility of using cartilage-derived morphogenetic protein-1 (CDMP1) induced dermal fibroblasts (DFs) as seed cells and polyglycolide (PGA) as scaffold for fibrocartilage engineering. DFs isolated from canine were expanded and seeded on PGA scaffold to fabricate cell/scaffold c...

journal_title：Biomaterials

authors： Zhao G,Yin S,Liu G,Cen L,Sun J,Zhou H,Liu W,Cui L,Cao Y

更新日期：2009-07-01 00:00:00

abstract：:The introduction of vaccines is regarded as one of the most successful medical interventions to date. However, there is a clear need for the development of new vaccines for diseases which require the induction of a potent cellular immune response. Advancements in the field of vaccine research have resulted in a move a...

journal_title：Biomaterials

authors： Moran HBT,Turley JL,Andersson M,Lavelle EC

更新日期：2018-11-01 00:00:00

abstract：:This study addresses the problem of antibiotic resistance in adhesive, biomaterial-centred infections. It is suggested that this anionic, extracapsular, polysaccharide slime produced by bacteria protects them from antibiotics and sequesters critical ions from the surface of biomaterials. Biofilm-enclosed bacteria on t...

journal_title：Biomaterials

authors： Gristina AG,Hobgood CD,Webb LX,Myrvik QN

更新日期：1987-11-01 00:00:00

abstract：:This article is a review of recent developments of polymer-related stents mainly employed in the coronary arteries, including polymer-coated stents, biostable stents and biodegradable stents. Polymer paving is covered as well. The problems with the stents currently investigated and the development of new stents are di...

journal_title：Biomaterials

authors： Peng T,Gibula P,Yao KD,Goosen MF

更新日期：1996-04-01 00:00:00

abstract：:The photodynamic activity of a carrier-sensitizer system consisting of heterotopic colloidal nanoparticles (diameter 100-1000 nm) of a cationic amphiphilic cyclodextrin, heptakis(2-omega-amino-O-oligo(ethylene oxide)-6-hexylthio)-beta-CD (SC6CDNH2) encapsulating the anionic 5,10,15,20-tetrakis(4-sulfonatophenyl)-21H,2...

journal_title：Biomaterials

authors： Sortino S,Mazzaglia A,Monsù Scolaro L,Marino Merlo F,Valveri V,Sciortino MT

更新日期：2006-08-01 00:00:00

abstract：:Cells form hollow, spheroidal structures during the development of many tissues, including the ocular lens, inner ear, and many glands. Therefore, techniques for in vitro formation of hollow spheroids are valued for studying developmental and disease processes. Current in vitro methods require cells to self-organize i...

journal_title：Biomaterials

authors： Wang E,Wang D,Geng A,Seo R,Gong X

更新日期：2017-10-01 00:00:00

abstract：:The effects of phosphorylated chitin (P-chitin) on the tissue responses to two kinds of calcium phosphate cements (CPCs) were investigated using experimental rabbits. One of them consisting of monocalcium phosphate monohydrate, calcium oxide, 1 M phosphate buffer (pH: 7.4) and different amounts of P-chitin (CPC-I or P...

journal_title：Biomaterials

authors： Wang X,Ma J,Feng Q,Cui F

更新日期：2002-12-01 00:00:00

abstract：:Direct reprogramming strategies enable rapid conversion of somatic cells to cardiomyocytes or cardiomyocyte-like cells without going through the pluripotent state. A recently described protocol couples Yamanaka factor induction with pluripotency inhibition followed by BMP4 treatment to achieve rapid reprogramming of m...

journal_title：Biomaterials

authors： Smith AW,Hoyne JD,Nguyen PK,McCreedy DA,Aly H,Efimov IR,Rentschler S,Elbert DL

更新日期：2013-09-01 00:00:00

abstract：:Constitutive models are developed, based on the results of confined compression testing, to describe the visco-elastic, and non-linear elasto-plastic behaviour of morsellised cortico-cancellous bone (MCB). It is found that the elastic modulus, E of MCB can be expressed as a linear function of the applied pressure, p. ...

journal_title：Biomaterials

authors： Phillips A,Pankaj P,May F,Taylor K,Howie C,Usmani A

更新日期：2006-03-01 00:00:00

abstract：:Menisci are one of the most commonly injured parts of the knee with a limited healing potential. This study focuses on fabrication and characterization of biomimetic surfaces for meniscal tissue engineering. To achieve this, a combination of hyaluronic acid/chitosan (HA/CH) mutilayers with covalently immobilized major...

journal_title：Biomaterials

authors： Tan GK,Dinnes DL,Butler LN,Cooper-White JJ

更新日期：2010-08-01 00:00:00

abstract：:In contractile tissues such as myocardium, functional properties are directly related to the cellular orientation and elongation. Thus, tissue engineering of functional cardiac patches critically depends on our understanding of the interaction between multiple guidance cues such as topographical, adhesive or electrica...

journal_title：Biomaterials

authors： Au HT,Cheng I,Chowdhury MF,Radisic M

更新日期：2007-10-01 00:00:00