Age-related changes to oscillatory dynamics in hippocampal and neocortical networks.

abstract：:Inhibitors of protein and mRNA syntheses inhibit long-term memory (LTM), but we lack information about the time windows during which those inhibitors are effective. Anisomycin (a protein synthesis translation inhibitor) was given to Hermissenda crassicornis which had received sufficient Pavlovian conditioning to produ...

journal_title：Neurobiology of learning and memory

authors： Epstein HT,Child FM,Kuzirian AM,Alkon DL

更新日期：2003-03-01 00:00:00

abstract：:Nearly 100 years ago, Ivan Pavlov demonstrated that dogs could learn to use a neutral cue to predict a biologically relevant event: after repeated predictive pairings, Pavlov's dogs were conditioned to anticipate food at the sound of a bell, which caused them to salivate. Like sustenance, danger is biologically releva...

journal_title：Neurobiology of learning and memory

authors： VanElzakker MB,Dahlgren MK,Davis FC,Dubois S,Shin LM

更新日期：2014-09-01 00:00:00

abstract：:Attempts were made to further analyze the role of 5-HT1A receptors in consolidation of learning by evaluating the role of these receptors in cognitively normal and impaired animals. The effects of post-training administration of 8-OH-DPAT and 5-HT1A receptor antagonists, WAY 100135, WAY 100635, and S-UH-301, plus the ...

journal_title：Neurobiology of learning and memory

authors： Meneses A,Hong E

更新日期：1999-03-01 00:00:00

abstract：:Recent evidence suggests that an interaction of noradrenaline (NE) and cortisol (CORT) during encoding leads to greater consolidation of emotional memories. Convergent models of posttraumatic stress disorder (PTSD) suggest the release of CORT and NE lead to greater intrusive memories in PTSD. This study examined the e...

journal_title：Neurobiology of learning and memory

authors： Nicholson EL,Bryant RA,Felmingham KL

更新日期：2014-07-01 00:00:00

abstract：:Activity dependent calcium entry into neurons can initiate a form of synaptic plasticity called long-term potentiation (LTP). This phenomenon is considered by many to be one possible cellular mechanism underlying learning and memory. The calcium entry that induces this phenomenon can occur when N-methyl-D-aspartate re...

journal_title：Neurobiology of learning and memory

authors： Woodside BL,Borroni AM,Hammonds MD,Teyler TJ

更新日期：2004-03-01 00:00:00

abstract：:The specific sigma-receptor agonist (+)-SKF 10047 and antagonist BD 1047 were used to investigate whether this receptor was involved in passive-avoidance training in the day-old chick. We found 300 microM (+)-SKF 10047 to be amnesic when injected into the lobus parolfactorius 5 h after training (p < .01). Higher or lo...

journal_title：Neurobiology of learning and memory

authors： Freeman FM,Young IG

更新日期：2001-05-01 00:00:00

abstract：:Neuroplastin 65 (NP65) is a brain-specific glycoprotein component of synaptic membrane, which is predominantly located in the forebrain such as the cortex, amygdala and striatum and hippocampus. Previous studies have shown that NP65 is implicated in synaptic plasticity, so it was hypothesized to play roles in cognitiv...

journal_title：Neurobiology of learning and memory

authors： Amuti S,Tang Y,Wu S,Liu L,Huang L,Zhang H,Li H,Jiang F,Wang G,Liu X,Yuan Q

更新日期：2016-01-01 00:00:00

abstract：:In insects, cholinergic neurons are thought to transmit olfactory conditioned stimulus (CS) to the sites for associating the CS with unconditioned stimulus (US), but the types of acetylcholine (ACh) receptor used by neurons participating in the association have not been determined. In cockroaches, a type of nicotinic ...

journal_title：Neurobiology of learning and memory

authors： Watanabe H,Matsumoto CS,Nishino H,Mizunami M

更新日期：2011-01-01 00:00:00

abstract：:Down syndrome (DS) has an incidence of about 1/700 births, and is therefore the most common cause of cognitive and behavioral impairments in children. Recent studies on mouse models of DS indicate that a number of pharmacotherapies could be beneficial for restoring cognitive abilities in individuals with DS. Attention...

journal_title：Neurobiology of learning and memory

authors： Heller HC,Salehi A,Chuluun B,Das D,Lin B,Moghadam S,Garner CC,Colas D

更新日期：2014-12-01 00:00:00

abstract：:Recently developed neuroimaging and electrophysiological techniques are allowing us to answer fundamental questions about how behavioral states regulate our perception of the external environment. Studies using these techniques have yielded surprising insights into how sensory processing is affected at the earliest st...

journal_title：Neurobiology of learning and memory

authors： Aton SJ

更新日期：2013-11-01 00:00:00

abstract：:Although tissue type plasminogen activator (tPA) and brain derived neurotrophic factor (BDNF) have been extensively described to influence brain outcomes in a number of disorders, their roles during physiological aging are poorly investigated. In the present study, we investigated whether maintenance of mice in differ...

journal_title：Neurobiology of learning and memory

authors： Obiang P,Maubert E,Bardou I,Nicole O,Launay S,Bezin L,Vivien D,Agin V

更新日期：2011-09-01 00:00:00

abstract：:The entorhinal cortex (EC) has been shown to be an integral piece of the hippocampal memory system. It sits in a unique position within the brain with strong, intricate, reciprocal connectivity with the hippocampus as well as a vast array of neocortical regions. Topographical patterns of afferent and efferent projecti...

journal_title：Neurobiology of learning and memory

authors： Morrissey MD,Takehara-Nishiuchi K

更新日期：2014-11-01 00:00:00

abstract：:Rats were trained to run on a staircase stopping on the 3rd, 6th, 9th, and 12th steps (correct responses). Stopping on any other step was considered an error. Acute administration of 0.5 mg/kg of arecoline 15 min before the trial improved behavior and 3.5 mg/kg of arecoline caused a reduction of correct responses. An ...

journal_title：Neurobiology of learning and memory

authors： Molinengo L,Orsetti M,Pastorello B,Scordo I,Ghi P

更新日期：1995-03-01 00:00:00

abstract：:It has been shown that the brain has its own intrinsic renin-angiotensin system (RAS) and angiotensin-(1-7) (Ang-(1-7)) is particularly interesting, because it appears to counterbalance most of the Ang II effects. Ang-(1-7) exerts its biological function through activation of the G-protein-coupled receptor Mas. Intere...

journal_title：Neurobiology of learning and memory

authors： Lazaroni TL,Raslan AC,Fontes WR,de Oliveira ML,Bader M,Alenina N,Moraes MF,Dos Santos RA,Pereira GS

更新日期：2012-01-01 00:00:00

abstract：:Recent research has begun to demonstrate that specific subunits of GABA(A) receptors may be involved in the normal expression of specific behaviors. The present research used mice with GABA(A) receptors whose alpha1 subunits contained mutations of serine 270 to histidine and leucine 277 to alanine in the TM2 region. T...

journal_title：Neurobiology of learning and memory

authors： Berry RB,Werner DF,Wang X,Jablonski MM,Homanics GE,Mittleman G,Matthews DB

更新日期：2008-10-01 00:00:00

abstract：:Considerable work demonstrates that Pavlovian fear conditioning depends on N-methyl-D-aspartate (NMDA) receptor-dependent plasticity within the amygdala. In addition, the bed nucleus of the stria terminalis (BNST) has also been implicated in fear conditioning, particularly in the expression of fear to poor predictors ...

journal_title：Neurobiology of learning and memory

authors： Ressler RL,Goode TD,Evemy C,Maren S

更新日期：2020-10-01 00:00:00

abstract：:The impact of past history on behavior across the life span is largely unknown. This is why the role of previous experience in subsequent memory performances has been studied in a combined longitudinal (animals repeatedly tested) and cross-sectional (animals tested once at various ages) study, in male Sprague-Dawley r...

journal_title：Neurobiology of learning and memory

authors： Dellu F,Mayo W,Vallee M,Le Moal M,Simon H

更新日期：1997-03-01 00:00:00

abstract：:Growing evidence indicates that antagonists of the 5-hydroxytryptamine (serotonin) receptor(6) (5-HT(6)) improve memory and reverse amnesia although the mechanisms involved are poorly understood. Hence, in this paper RT-PCR was used to evaluate changes in mRNA expression of 5-HT(6) receptor in trained and untrained ra...

journal_title：Neurobiology of learning and memory

authors： Huerta-Rivas A,Pérez-García G,González-Espinosa C,Meneses A

更新日期：2010-01-01 00:00:00

abstract：:Heart rate (HR) conditioning in rabbits is a widely used model of classical conditioning of autonomic responding that is noted for being similar to the development of conditioned heart rate slowing (bradycardia) in humans. We have shown previously that in addition to HR changes to a tone conditioned stimulus (CS), the...

journal_title：Neurobiology of learning and memory

authors： Burhans LB,Schreurs BG

更新日期：2013-02-01 00:00:00

abstract：:Expression of immediate-early genes, like Egr-1, has been shown to be induced by activity-dependent synaptic plasticity or behavioral training and is widely thought to play an important role in long-term memory (LTM) formation. However, little is known about the role of Egr-1 in the maintenance of memory storage. Here...

journal_title：Neurobiology of learning and memory

authors： Katche C,Goldin A,Gonzalez C,Bekinschtein P,Medina JH

更新日期：2012-10-01 00:00:00

abstract：:Human genetic studies established MET gene as a risk factor for autism spectrum disorders. We have previously shown that signaling mediated by MET receptor tyrosine kinase, expressed in early postnatal developing forebrain circuits, controls glutamatergic neuron morphological development, synapse maturation, and corti...

journal_title：Neurobiology of learning and memory

authors： Xia B,Wei J,Ma X,Nehme A,Liong K,Cui Y,Chen C,Gallitano A,Ferguson D,Qiu S

更新日期：2021-01-29 00:00:00

abstract：:The current review provides a historical perspective on the evolution of hypothesized mechanisms for senescent neurophysiology, focused on the CA1 region of the hippocampus, and the relationship of senescent neurophysiology to impaired hippocampal-dependent memory. Senescent neurophysiology involves processes linked t...

journal_title：Neurobiology of learning and memory

authors： Foster TC

更新日期：2019-10-01 00:00:00

abstract：:Much has been said about how significant life events modulate our response to stimuli that are integral to those events. However, we know less about the more general consequences of these events, that is, how they affect subsequent learning abilities that are seemingly irrelevant to the initial event. Here, it is prop...

journal_title：Neurobiology of learning and memory

authors： Shors TJ

更新日期：2006-03-01 00:00:00

abstract：:Drug addiction can be understood as a pathological subversion of normal brain learning and memory processes strengthened by the motivational impact of drug-associated stimuli, leading to the establishment of compulsive drug-seeking habits. Such habits evolve through a cascade of complex associative processes with Pavl...

journal_title：Neurobiology of learning and memory

authors： Robbins TW,Everitt BJ

更新日期：2002-11-01 00:00:00

abstract：:MeCP2 is required both during postnatal neurodevelopment and throughout the adult life for brain function. Although it is well accepted that MeCP2 in the maturing nervous system is critical for establishing normal development, the functions of MeCP2 during adulthood are poorly understood. Particularly, the requirement...

journal_title：Neurobiology of learning and memory

authors： Gulmez Karaca K,Brito DVC,Zeuch B,Oliveira AMM

更新日期：2018-03-01 00:00:00

abstract：:Fetal alcohol exposure in human and rodents produces a number of cognitive deficits including impairments in learning and memory. Recent evidence in our laboratory has shown that fetal alcohol-exposed (FAE) rats respond differently to systemic administration of cholinergic drugs when tested for vigilance and locomotor...

journal_title：Neurobiology of learning and memory

authors： Nagahara AH,Handa RJ

更新日期：1999-11-01 00:00:00

abstract：:Pre-test exposure to training-related cues is known to improve subsequent retention performance. To identify brain regions engaged in processes promoted by retrieval cues, a brain imaging approach using the [6-14C]glucose autoradiographic technique was used. Sprague-Dawley rats trained in a brightness discrimination a...

journal_title：Neurobiology of learning and memory

authors： Boujabit M,Bontempi B,Destrade C,Gisquet-Verrier P

更新日期：2003-01-01 00:00:00

abstract：:Evidence is reviewed that behavioral training and neural injury can engage metaplastic processes that regulate adaptive potential. This issue is explored within a model system that examines how training affects the capacity to learn within the lower (lumbosacral) spinal cord. Response-contingent (controllable) stimula...

journal_title：Neurobiology of learning and memory

authors： Grau JW,Huang YJ

更新日期：2018-10-01 00:00:00

abstract：:The use of visual habituation in the study of infant cognition and learning is reviewed. This article traces the history of the technique, underlying theory, and procedural variation in its measurement. In addition, we review empirical findings with respect to the cognitive processes that presumably contribute to habi...

journal_title：Neurobiology of learning and memory

authors： Colombo J,Mitchell DW

更新日期：2009-09-01 00:00:00

abstract：:The recall of a previously formed fear memory triggers a process through which synapses in the amygdala become "destabilized". This labile state at retrieval may be critical for the plasticity required to modify, update, or disrupt long-term memories. One component of this process involves the rapid internalization of...

journal_title：Neurobiology of learning and memory

authors： Ferrara NC,Trask S,Pullins SE,Helmstetter FJ

更新日期：2019-12-01 00:00:00