Abstract:
:Social experiences may moderate genetic influences on alcohol dependence (AD) symptoms. Consistent with this hypothesis, Park, Sher, Todorov, and Heath (2011) previously reported interactions between the dopamine D4 receptor gene (DRD4) and developmentally specific environments in the etiology of AD symptoms during emerging and young adulthood. Using a longitudinal cohort of n = 367 White participants followed from ages 18 to 27 years, we examine a series of similar interactions between DRD4 and developmentally sensitive contexts including childhood adversity and work and family roles. In contrast to previous results, we observed no significant interactions between DRD4 and childhood adversity. Overall, results further highlight the need for longitudinal studies of Gene × Environment interaction in the behavioral sciences and the difficulty of identifying candidate Gene × Environment interaction effects that are consistent across studies.
journal_name
J Abnorm Psycholjournal_title
Journal of abnormal psychologyauthors
Carlson MD,Harden KP,Kretsch N,Corbin WR,Fromme Kdoi
10.1037/abn0000120subject
Has Abstractpub_date
2015-11-01 00:00:00pages
1043-9issue
4eissn
0021-843Xissn
1939-1846pii
2015-52362-015journal_volume
124pub_type
杂志文章abstract::Drunk driving, a major contributor to alcohol-related mortality, has been linked to a variety of other alcohol-related (e.g., Alcohol Dependence, early age at first drink) and non-alcohol-related externalizing behaviors. In a sample of 517 same-sex twin pairs from the National Longitudinal Study of Adolescent Health, ...
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journal_title:Journal of abnormal psychology
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更新日期:2017-11-01 00:00:00
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journal_title:Journal of abnormal psychology
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doi:10.1037//0021-843x.108.4.662
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pub_type: 杂志文章
doi:10.1037/abn0000143
更新日期:2016-05-01 00:00:00
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doi:10.1037/0021-843X.108.1.24
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journal_title:Journal of abnormal psychology
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journal_title:Journal of abnormal psychology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2005-02-01 00:00:00
abstract::In light of expanding legalization of cannabis and swelling debate about the potential risks, particularly for younger users, understanding acute cannabis effects among adolescents and emerging adults is more important than ever. Contemporary models of addiction development identify subjective drug responses as centra...
journal_title:Journal of abnormal psychology
pub_type: 临床试验,杂志文章
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abstract::Depression in adults is associated with deficits in a number of cognitive domains, however it remains less clear how early in development theses deficits can be detected in early onset depression. There are several different hypotheses about the links between cognitive function and depression. For example, it has been...
journal_title:Journal of abnormal psychology
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journal_title:Journal of abnormal psychology
pub_type: 杂志文章
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更新日期:2011-05-01 00:00:00
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journal_title:Journal of abnormal psychology
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更新日期:2011-02-01 00:00:00