Abstract:
:Patterns and features of substance use and abuse vary across the menstrual cycle in humans. Yet, little work has systematically examined the within-person relationships between ovarian hormone changes and alcohol use across the menstrual cycle. Our study was the first to examine the roles of within-person levels of estradiol (E2) and progesterone (P4) in relation to daily alcohol use and binge drinking in young women. Participants were 22 naturally cycling women, ages 18-22, recruited through a university subject pool who reported any alcohol use and who completed a screening visit assessing study eligibility, followed by 35 subsequent days of data collection. E2 and P4 were obtained via enzyme immunoassay of saliva samples collected by participants each morning, 30 min after waking. Presence and degree of daily substance use were obtained using an adaptation of the Timeline FollowBack Interview completed daily. Results indicated that elevated E2 in the context of decreased P4 levels were associated with higher risk of drinking and binge drinking. These effects were present only on weekend days. Results are suggestive of a dual risk model in which both ovulatory E2 increases and perimenstrual P4 decreases increase risk for drinking. Differential associations of steroids with drinking across the menstrual cycle may suggest the need for clinical assessment of substance use to take into account hormone dynamics and menstrual cycle phase. (PsycINFO Database Record
journal_name
J Abnorm Psycholjournal_title
Journal of abnormal psychologyauthors
Martel MM,Eisenlohr-Moul T,Roberts Bdoi
10.1037/abn0000304subject
Has Abstractpub_date
2017-11-01 00:00:00pages
1104-1113issue
8eissn
0021-843Xissn
1939-1846pii
2017-51268-008journal_volume
126pub_type
杂志文章abstract::Despite clear diagnostic distinctions, schizophrenia and autism share symptoms on several dimensions. Recent research has suggested the two disorders overlap in etiology, particularly with respect to inherited and noninherited genetic factors. Studying the relationship between psychotic-like and autistic-like symptoms...
journal_title:Journal of abnormal psychology
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journal_title:Journal of abnormal psychology
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journal_title:Journal of abnormal psychology
pub_type: 杂志文章
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journal_title:Journal of abnormal psychology
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journal_title:Journal of abnormal psychology
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journal_title:Journal of abnormal psychology
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doi:
更新日期:2003-02-01 00:00:00
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journal_title:Journal of abnormal psychology
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journal_title:Journal of abnormal psychology
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journal_title:Journal of abnormal psychology
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journal_title:Journal of abnormal psychology
pub_type: 杂志文章
doi:10.1037//0021-843x.101.2.277
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journal_title:Journal of abnormal psychology
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journal_title:Journal of abnormal psychology
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journal_title:Journal of abnormal psychology
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journal_title:Journal of abnormal psychology
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pub_type: 杂志文章,随机对照试验
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journal_title:Journal of abnormal psychology
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journal_title:Journal of abnormal psychology
pub_type: 杂志文章
doi:10.1037/abn0000010
更新日期:2015-02-01 00:00:00
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journal_title:Journal of abnormal psychology
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