Abstract:
:Zinc is proposed to have an important role in the morphology, viability and motility of spermatozoa. There are inconsistent reports on the association between seminal plasma zinc concentration and male infertility. For this purpose, papers reporting the level of seminal zinc among asthenozoospermic groups were selected and used for further analysis. This meta-analysis of previous published studies was performed to obtain more precise information on the association between seminal plasma zinc and asthenozoospermia. Relevant studies for inclusion were identified after preliminary investigation of research papers published on electronic databases up to February 2015. Eight reports and 475 subjects were finally included in the meta-analysis. In the overall analysis, a statistically significant reduction in seminal plasma zinc concentrations was observed in asthenozoospermic infertile men. Random-effects method was used to evaluate the summary effect size due to the presence of significant heterogeneity. The effect of zinc on asthenozoospermia was significant (Hedge's G effect size = -0.506, 95% confidence interval (95% CI): -0.998 to -0.014, P = 0.044). Taken together, despite of significant statistical heterogeneity between studies, our findings were indicative of significant association between zinc concentration and asthenozoospermia. In conclusion, the meta-analysis suggests that seminal plasma zinc concentration is negatively associated with male infertility.
journal_name
Andrologiajournal_title
Andrologiaauthors
Taravati A,Tohidi Fdoi
10.1111/and.12494subject
Has Abstractpub_date
2016-08-01 00:00:00pages
646-53issue
6eissn
0303-4569issn
1439-0272journal_volume
48pub_type
杂志文章,meta分析相关文献
ANDROLOGIA文献大全abstract::There is growing concern that abnormalities in male reproductive health are becoming more frequent. The most fundamental change has been the striking decline in sperm counts and semen quality. The effect of maternal exposure of rats to the oestrogenic environmental substance p-nonylphenol (p-NP) was determined in this...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1046/j.1439-0272.1999.00246.x
更新日期:1999-03-01 00:00:00
abstract::Decreased sperm quality was caused by oxidative stress in semen from patients with leucocytospermia. Curcumin is a traditional Chinese herbal monomer extracted from Zingiberaceae turmeric and zedoary turmeric and has antioxidative and anti-inflammatory effects. This study aimed to investigate the effects and specific ...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12760
更新日期:2017-12-01 00:00:00
abstract::Nonylphenol (NP) is known as an environmental pollutant that has adverse effects on the spermatogenesis process. In this review, we focus on (1999-2020) studies on the effect of this pollutant on the sperm parameters and the male reproductive system. Spermatogenesis is a process in which male spermatogonia (primary ge...
journal_title:Andrologia
pub_type: 杂志文章,评审
doi:10.1111/and.13748
更新日期:2020-07-14 00:00:00
abstract::The sex chromosome-discordant chimerism 46,XX/46,XY is rarely found in humans with a phenotypically normal appearance, and this lack of phenotypic changes and the rarity of chimerism make it difficult to identify its exact incidence. Here, we report a case of this sex chromosome-discordant chimerism diagnosed by cytog...
journal_title:Andrologia
pub_type:
doi:10.1111/and.13215
更新日期:2019-04-01 00:00:00
abstract::Over the past decades, there is an increasing number of association studies of telomere length (TL) and the risk and recurrence of prostate cancer (PCa), but the results are inconsistent. Hence, we identify the relevant studies published in English on or before 10 January 2019 conducting a literature review in the ele...
journal_title:Andrologia
pub_type: 杂志文章,meta分析
doi:10.1111/and.13304
更新日期:2019-08-01 00:00:00
abstract::The effect of chronic chloroquine administration on prostaglandin E1 (PGE1) and human chorionic gonadotropin (hCG) stimulation of testosterone secretion by the rat Leydig cells was studied. Adult albino (Wistar strain) rats were injected with 4 mg/kg body weight of chloroquine phosphate every other day for 30 days. At...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1987.tb01900.x
更新日期:1987-09-01 00:00:00
abstract::The simultaneous swimming up and down from identical semen specimens suggested that the separation efficiency of progressively motile sperm by the swim-down method was superior to that of the swim-up method. The swimming down was performed in a small plastic funnel, the bottom of which was plugged with a 2.5 ml dispos...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1991.tb02485.x
更新日期:1991-01-01 00:00:00
abstract::Little is known about the biological and clinical significance of bilaterally enlarged testes (bilateral megalotestes or macroorchidism). We have investigated clinical, endocrine and spermatological characteristics of 135 andrological patients with a testicular volume of more than 25 ml bilaterally. 135 patients with ...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1995.tb01094.x
更新日期:1995-07-01 00:00:00
abstract::Thirty-five couples with a variety of infertility problems were treated by a sperm-washing and intrauterine-insemination method. The husband's semen was washed with a modified Biggers, Whitten, and Whittingham's medium to obtain a seminal plasma-free, highly concentrated sperm suspension for intrauterine insemination....
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1985.tb00955.x
更新日期:1985-01-01 00:00:00
abstract::The necessity to check up exactly the procedure in vasectomy by the so called - Hamburg Model - is demonstrated by 4 cases. Although these patients were sterilized we could prove fertility on spermiogram, and observed pregnancy in 3 cases. Consequences in matter of law for the surgeon is pointed out. ...
journal_title:Andrologia
pub_type: 杂志文章
doi:
更新日期:1981-07-01 00:00:00
abstract::Dynamic assessment of sperm DNA fragmentation (SDF) has shown to give fuller understanding of stallion semen quality; however, there have been limited attempts to use this parameter to investigate seasonal changes in productive functions. The aims of this study were to: (a) establish a reliable mathematical model to d...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13545
更新日期:2020-05-01 00:00:00
abstract::Shilajit is claimed as a Vajikarak (aphrodisiac) and used for the treatment of male infertility by traditional healers of the Indian subcontinent. Therefore, the present investigation was designed to assess the effectiveness of Shilajit for treatment of male infertility resulting from exposure to perilous chemicals. E...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13064
更新日期:2018-10-01 00:00:00
abstract::The influence of bacteria and/or leukocytes on the outcome of IVF or ICSI is influenced by three factors which have little in common with in vivo conditions: 1) The process of ejaculate preparation (swim-up, Percoll) with antibiotic buffered media; 2) The small amount of inseminated spermatozoa (100,000 per culture); ...
journal_title:Andrologia
pub_type: 杂志文章,评审
doi:10.1111/j.1439-0272.1998.tb02833.x
更新日期:1998-01-01 00:00:00
abstract::Erectile dysfunction could be an early sign of endothelial dysfunction and, therefore, of cardiovascular disease, with which it shares many risk factors. Among reversible risk factors, physical inactivity is one of the most important. Regular physical exercise has been shown to improve erectile function through differ...
journal_title:Andrologia
pub_type: 杂志文章,评审
doi:10.1111/and.13264
更新日期:2019-06-01 00:00:00
abstract::This study was planned to determine the relationship between semen quality parameters and the levels of biochemical constituents of seminal plasma of Teddy (Capra hircus) buck semen. For this purpose, semen ejaculates were collected from five mature healthy Teddy bucks. All the experimental bucks were kept under natur...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12940
更新日期:2018-04-01 00:00:00
abstract::The aim of this study was to evaluate the hypothalamic-pituitary-gonadal axis functionality on a bodybuilding competitioner before, during and after the use of anabolic-androgenic steroids. A young healthy man was followed up for 4 months. The subject reported his drug administration protocol through periodic intervie...
journal_title:Andrologia
pub_type:
doi:10.1111/and.13107
更新日期:2018-11-01 00:00:00
abstract::Research has revealed that reactive oxygen species (ROS) negatively affect sperm function, both in vivo and in vitro. Sperm preparation techniques for assisted reproductive technologies (ART) are potential causes for additional ROS production. This study aimed to correlate the concentration of exogenous H(2)O(2) with ...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.2009.00980.x
更新日期:2010-06-01 00:00:00
abstract::This study aimed to investigate whether gene transfer of myocardin to the penis of diabetic rats can modulate corpus cavernosum smooth muscle (CCSM) cells phenotype and restore erectile function. Five normal control rats, and 22 diabetic rats were randomly divided into four groups: rats transfected with adCMV-myocardi...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12261
更新日期:2015-04-01 00:00:00
abstract::The aim of the study was to statistically prove that the HBA(®) test is an efficient practical method for andrologists to determine the fertility potential as well as to measure the efficiency of oral supplement therapy in case of male infertility. In the study, 175 patients were involved and it also included the foll...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12296
更新日期:2015-06-01 00:00:00
abstract::The presence of 2 million or more peroxidase-positive white blood cells per ml of semen, or the diagnosis of male accessory gland infection, is associated with important biochemical and biological changes in semen plasma and in the spermatozoa, reducing their fertilizing potential in vitro and in vivo (e.g., during in...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1998.tb02823.x
更新日期:1998-01-01 00:00:00
abstract::Cyclophosphamide is a drug used for chemotherapy and as an immune-suppressive in the organ transplantation. Despite its many clinical implications in the treatment of cancers, this drug has toxic effects on the reproductive system. This study aimed to evaluate the effect of ghrelin against the damages caused by cyclop...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12883
更新日期:2018-03-01 00:00:00
abstract::Various nuclear sperm alterations are reported in patients with syndromic teratozoospermia; however, this has not been clearly identified yet in total polymorphic teratozoospermia. The aim of this study was to analyse sperm aneuploidy, DNA integrity and chromatin packaging in 45 infertile patients with total polymorph...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13252
更新日期:2019-06-01 00:00:00
abstract::Sterile semen of three brothers was investigated biochemically. Most strikingly was the strong similarity of both the amino acid and the carbohydrate composition of the semen. Inside the spermatozoa much more fructose and glucose was present than normally is found. It could be shown that in the seminal plasma peptides...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1975.tb01221.x
更新日期:1975-01-01 00:00:00
abstract::Genetic factors that could mediate the pathogenesis of male reproductive disorders are largely unclear. Polymorphisms of cytochrome P4501A1 (CYP1A1), a key enzyme in the extrahepatic metabolism of lipophilic xenobiotics, have been shown to influence susceptibility to xenobiotics. Here, CYP1A1 polymorphisms were invest...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1998.tb01387.x
更新日期:1998-05-01 00:00:00
abstract::The percentage of y chromatin positive spermatozoa had been determined using the fluorescence microsopce technique. After staining procedure with Atebrin we counted 44.1 (+/- 3.9)% y poistive sperms, after staining with Quinacrine mustard the amount was 48,4 (+/- 4,3)%. With statistical methods we examined the correla...
journal_title:Andrologia
pub_type: 杂志文章
doi:
更新日期:1977-01-01 00:00:00
abstract::The events occurring at the maternal-foetal interface define a successful pregnancy but the current paradigm has shifted towards assessing the contribution of spermatozoa for embryogenesis. Spermatozoa with defective DNA integrity may fertilise the oocyte but affect subsequent embryonic development. The present case-c...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13171
更新日期:2019-02-01 00:00:00
abstract::This study scrutinised the ameliorative properties of grape seed extract (GSE) in dexamethasone (DEX)-induced testicular and thyroid dysfunction associated with oxidative stress in male albino rats. Thirty-two healthy adult male albino rats were divided into four groups of eight animals each: normal, DEX control, DEX ...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13002
更新日期:2018-06-01 00:00:00
abstract::The calcium-binding proteins (CBPs) of mouse epididymal spermatozoa were analysed by mobility changes in the presence of added Ca2+ in two-dimensional sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE). The expression patterns of relatively high molecular weight CBPs (Mr > 20 kDa) were different bet...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1046/j.1439-0272.2001.00419.x
更新日期:2001-07-01 00:00:00
abstract::Lipomas are the most common benign tumours that originate from adipose tissue and can develop in any anatomical location where the adipose tissue layer is present in the body. Penile lipoma cases are very rare in the literature. Our case is a 21-year-old male patient who underwent TIPU operation 8 years ago due to dis...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13289
更新日期:2019-07-01 00:00:00
abstract::In a controlled double blind trial the effectiveness and tolerability of Kallikrein in patients suffering from astheno-oligozoospermia was examined in comparison to placebo. 30 patients with astheno-oligozoospermia of idiopathic origin entered the study; they were subdivided into two homogeneous groups of 15 patients ...
journal_title:Andrologia
pub_type: 临床试验,杂志文章
doi:10.1111/j.1439-0272.1984.tb00256.x
更新日期:1984-03-01 00:00:00