A novel junctional adhesion molecule A (CgJAM-A-L) from oyster (Crassostrea gigas) functions as pattern recognition receptor and opsonin.

abstract：:Individual adult channel catfish were immunized by immersion in an antigen bath containing dinitrophenylated-horse serum albumin. Anti-DNP hemagglutination titers of serum and cutaneous mucus were determined following both primary and secondary bath immunization. The results showed that five of the six fish had a cuta...

journal_title：Developmental and comparative immunology

authors： Lobb CJ

更新日期：1987-10-01 00:00:00

abstract：:The function of thioester-containing proteins (TEPs) in the immune defense of the fruit fly Drosophila melanogaster is yet mostly unexplored. Recently, we showed the involvement of TEP4 in the activation of humoral and phenoloxidase immune responses of Drosophila against the pathogenic bacteria Photorhabdus luminescen...

journal_title：Developmental and comparative immunology

authors： Shokal U,Eleftherianos I

更新日期：2017-11-01 00:00:00

abstract：:The appearance of antibody genes over evolution coincided with the origin of the vertebrates. Reptiles are of great interest in evolution since they are the link between the amphibians, birds, and mammals. This work describes the presence of a gene in the reptile leopard gecko (Eublepharis macularius) where phylogenet...

journal_title：Developmental and comparative immunology

authors： Deza FG,Espinel CS,Beneitez JV

更新日期：2007-01-01 00:00:00

abstract：:In mammals, tripartite motif (TRIM)-containing proteins are involved in interferon (IFN)-mediated antiviral response as pivotal players endowed with antiviral effects and modulatory capacity. Teleost fish have a unique subfamily of TRIM, called finTRIM (fish novel TRIM, FTR) generated by genus- or species-specific dup...

journal_title：Developmental and comparative immunology

authors： Li YL,Zhao X,Gong XY,Dan C,Gui JF,Zhang YB

更新日期：2020-12-01 00:00:00

abstract：:Pacifastin is a recently classified family of serine proteinase inhibitors that play essential roles in various biological processes, including in the regulation of the melanization cascade. Here, a novel pacifastin-related gene, termed PmPacifastin-like, was identified from a reverse suppression subtractive hybridiza...

journal_title：Developmental and comparative immunology

authors： Sangsuriya P,Charoensapsri W,Chomwong S,Senapin S,Tassanakajon A,Amparyup P

更新日期：2016-01-01 00:00:00

abstract：:Lysozymes as an important immune factor, play vital roles in innate immune response against pathogen infection. In the present study, one c-type and g-type lysozymes were identified from Chinese giant salamander (Andrias davidianus). They shared highly conserved structural features with lysozymes from other species. S...

journal_title：Developmental and comparative immunology

authors： Yang H,Liu R,Cui D,Liu H,Xiong D,Liu X,Wang L

更新日期：2017-07-01 00:00:00

abstract：:In Xenopus, the type I transmembrane protein, CTX (cortical thymocyte-specific antigen of Xenopus), is hypothesized to play a role in thymocyte differentiation and/or thymic selection. The present studies were undertaken to gather additional evidence in support of a postulated association of CTX with a differentiation...

journal_title：Developmental and comparative immunology

authors： Robert J,Cohen N

更新日期：1998-09-01 00:00:00

abstract：:Heterogeneous nuclear ribonucleoproteins (hnRNPs) are highly conserved from nematode to mammal because they play an important role in several aspects of pre-mRNA maturation, including RNA packaging and alternative splicing. In Drosophila, the hnRNP A1 homolog hrp36 regulates alternative splicing in several genes, incl...

journal_title：Developmental and comparative immunology

authors： Lee CW,Chen IT,Chou PH,Hung HY,Wang KV

更新日期：2012-01-01 00:00:00

abstract：:The cytokine network is an important homeostatic system with potent activities in immune surveillance, growth, developmental and repair processes. Although interleukin-1beta (IL-1beta) is considered a pivotal pro-inflammatory cytokine, merely focussing on its inflammatory role would be too narrow an approach. Elucidat...

journal_title：Developmental and comparative immunology

authors： Huising MO,Stet RJ,Savelkoul HF,Verburg-van Kemenade BM

更新日期：2004-05-03 00:00:00

abstract：:CD8, belonging to the TCR complex, is the main marker molecule of CTLs. Although CD8 genes have been detected in many fish species, the analysis of teleost CD8+ cells has been limited because of the lack of antibodies. Using newly established mAbs against rainbow trout CD8α, we found high ratios of CD8α+ cells in trou...

journal_title：Developmental and comparative immunology

authors： Takizawa F,Dijkstra JM,Kotterba P,Korytář T,Kock H,Köllner B,Jaureguiberry B,Nakanishi T,Fischer U

更新日期：2011-07-01 00:00:00

abstract：:Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases mainly involved in extracellular matrix (ECM) degradation. We have cloned and identified BbMMPL2 as homolog of MMPs from adult amphioxus. Recombinant BbMMPL2 proteins underwent self-processing during refolding in vitro. The final ~23 kDa po...

journal_title：Developmental and comparative immunology

authors： Zhang Y,Zhang H,Kong Y,Feng L

更新日期：2012-07-01 00:00:00

abstract：:A cDNA clone coding for a Kazal protein was isolated from a cDNA library of Litopenaeus vannamei hemocytes. The full-length cDNA sequence is 1.32 kb long and encodes a 24 kDa protein. Four Kazal domains, 43-46 residues long, were detected in the deduced primary structure. Apparently, the first and second domains do no...

journal_title：Developmental and comparative immunology

authors： Jiménez-Vega F,Vargas-Albores F

更新日期：2005-01-01 00:00:00

abstract：:The human IL-1 receptor family is comprised of 11 membrane bound or soluble receptors and the IL-18 binding protein (IL-18BP). These receptors are dispersed across seven genomic loci, with the majority at a single locus. Direct orthologues were identified in the chicken at conserved genomic loci; however, the IL-18BP ...

journal_title：Developmental and comparative immunology

authors： Gibson MS,Steyn A,Kealy D,Kaspers B,Fife MS

更新日期：2021-01-01 00:00:00

abstract：:Soft tunic syndrome of Halocynthia roretzi manifests as soft, weak, and rupturable tunics, causing mass mortality. Utilizing liquid chromatography-tandem mass spectrometry (LC-MS/MS), innate immune response was established by comparing hemolymph protein profiles of ascidians with healthy or softened tunics. Of 100 pro...

journal_title：Developmental and comparative immunology

authors： Cha IS,Castillo CS,Nho SW,Hikima J,Aoki T,Jung TS

更新日期：2011-08-01 00:00:00

abstract：:The erythrocytes of various vertebrates, such as mice, rabbits, sheep, chickens, bullfrogs, and toads are lysed by normal snake sera. However, snake erythrocytes were not lysed by serum from different snake species. Putative natural antibody seems with different specificities to comprise heterogeneous antibodies. Thus...

journal_title：Developmental and comparative immunology

authors： Kawaguchi S,Muramatsu S,Mitsuhashi S

更新日期：1978-07-01 00:00:00

abstract：:A hemagglutinin was isolated from hemocytes of the ascidian, Halocynthia roretzi, by a procedure including extraction and ion-exchange chromatography on CM-cellulose. The molecular weight of the hemagglutinin was estimated to be 120,000 by gel filtration. It was resistant to acid treatment but sensitive to alkali or h...

journal_title：Developmental and comparative immunology

authors： Azumi K,Ozeki S,Yokosawa H,Ishii S

更新日期：1991-01-01 00:00:00

abstract：:The invariant chain (Ii) is the critical third chain required for the MHC class II heterodimer to be properly guided through the cell, loaded with peptide, and expressed on the surface of antigen presenting cells. Here, we report the isolation of the nurse shark Ii gene, and the comparative analysis of Ii splice varia...

journal_title：Developmental and comparative immunology

authors： Criscitiello MF,Ohta Y,Graham MD,Eubanks JO,Chen PL,Flajnik MF

更新日期：2012-03-01 00:00:00

abstract：:Bacterial challenge enhances phospholipase A(2) (PLA(2)) activity, which in turn induces biosynthesis of various eicosanoids that mediate non-self recognition signal to immune effectors in insects. But, there is little information on how PLA(2) activity is controlled after the non-self recognition. A recent genome ana...

journal_title：Developmental and comparative immunology

authors： Shrestha S,Kim Y

更新日期：2010-05-01 00:00:00

abstract：:In this study, an IL-8 homologue has been cloned and identified from South African clawed frog Xenopus laevis (designated XlIL-8). The open reading frame (ORF) of XlIL-8 consists of 312 bases encoding a protein of 103 amino acids. The chemokine CXC domain, which contained Glu-Leu-Arg (ELR) motif and four cysteine resi...

journal_title：Developmental and comparative immunology

authors： Cui X,Han Y,Pan Y,Xu X,Ren W,Zhang S

更新日期：2011-11-01 00:00:00

abstract：:There is a continuing debate on whether an antiviral immunity similar to vertebrate interferon response exists in invertebrates. Recent advances in penaeid immunology identified several new members of the Toll receptor family and one of these is LvToll3 (Litopenaeus vannamei Toll3). It is hypothesized in this study th...

journal_title：Developmental and comparative immunology

authors： Guanzon DAV,Maningas MBB

更新日期：2018-07-01 00:00:00

abstract：:We analyzed the effects of infection with Trichobilharzia ocellata on hemocytes of its snail host, Lymnaea stagnalis, and correlated them with successive stages of parasite development. Circulating hemocytes were studied at 0, 2, 4, 6, and 8 weeks post exposure (p.e.) with respect to cell number, distribution of subpo...

journal_title：Developmental and comparative immunology

authors： Amen RI,Tijnagel JM,van der Knaap WP,Meuleman EA,de Lange-de Klerk ES,Sminia T

更新日期：1991-04-01 00:00:00

abstract：:Brief pretreatment of cold shock at 13 °C for 3 min proved to be an inducer of heat shock protein 70 (HSP70) and improved stress tolerance as a molecular chaperone. With the improvement of air exposure tolerance, HSP70 in shrimp hemocytes was upregulated in mRNA and protein levels after cold shock. Both HSP70 RNA inte...

journal_title：Developmental and comparative immunology

authors： Guan W,Wei X,Nong W,Shao Y,Mao L

更新日期：2021-01-01 00:00:00

abstract：:Muscarinic receptors, which selectively take muscarine as their ligand, are critical for the immunological and physiological processes in animals. In the present study, the open region frame (ORF) of a homologue of muscarinic acetylcholine (ACh) receptor (mAChR) was amplified from oyster Crassostrea gigas (named as Cg...

journal_title：Developmental and comparative immunology

authors： Liu Z,Zhou Z,Wang L,Dong W,Qiu L,Song L

更新日期：2016-12-01 00:00:00

abstract：:Crustins are antibacterial proteins of ca. 7-14 kDa with a characteristic four-disulphide core-containing whey acidic protein (WAP) domain, expressed by the circulating haemocytes of crustaceans. Over 50 crustin sequences have been now reported from a variety of decapods, including crabs, lobsters, shrimp and crayfish...

journal_title：Developmental and comparative immunology

authors： Smith VJ,Fernandes JM,Kemp GD,Hauton C

更新日期：2008-01-01 00:00:00

abstract：:Acute hepatopancreatic necrosis disease (AHPND) is a recently emerged disease in aqua cultured shrimp that is caused by virulent strains of Vibrio parahaemolyticus (VP). Our previous study used transcriptomics to identify key pathogenic factors in the stomach of AHPND-infected shrimp (Litopenaeus vannamei), and here w...

journal_title：Developmental and comparative immunology

authors： Apitanyasai K,Chang CC,Ng TH,Ng YS,Liou JH,Lo CF,Lin SS,Wang HC

更新日期：2020-05-01 00:00:00

abstract：:White spot syndrome virus (WSSV), the causative agent of white spot disease (WSD), is a serious and aggressive shrimp viral pathogen with a worldwide distribution. At the genome replication stage (12 hpi), WSSV induces a metabolic rerouting known as the invertebrate Warburg effect, which boosts the availability of ene...

journal_title：Developmental and comparative immunology

authors： Hsieh YC,Chen YM,Li CY,Chang YH,Liang SY,Lin SY,Lin CY,Chang SH,Wang YJ,Khoo KH,Aoki T,Wang HC

更新日期：2015-11-01 00:00:00

abstract：:This study focused on an isolation and characterization of the circulating hemocytes in mud crab, Scylla olivacea. Isolation of specific cell types of hemocytes from crab hemolymph was accomplished by using 60% Percoll density gradient centrifugation. Four separated bands of the hemocytes were successfully obtained. C...

journal_title：Developmental and comparative immunology

authors： Mangkalanan S,Sanguanrat P,Utairangsri T,Sritunyalucksana K,Krittanai C

更新日期：2014-05-01 00:00:00

abstract：:Mannose-binding lectin (MBL) plays an important role in host immune responses against pathogens. LjMBL-like-1 was identified from Japanese sea bass (Lateolabrax japonicas), which has selectivity for galactose. Herein, this lectin might be better designated as galactose-binding lectin (LjGalBL-1). LjGalBL-1 transcripts...

journal_title：Developmental and comparative immunology

authors： Dang Y,Nie L,Chen J

更新日期：2020-03-01 00:00:00

abstract：:This study was undertaken to determine if a lack of V(L) domain variability could explain, in part, the failure of Atlantic cod to respond to immunization with the production of specific antibodies. The variability of cod V(L) regions was studied in 33 cDNA and two genomic clones. The variability of the CDRs was estim...

journal_title：Developmental and comparative immunology

authors： Widholm H,Lundbäck AS,Daggfeldt A,Magnadottir B,Warr GW,Pilström L

更新日期：1999-04-01 00:00:00

abstract：:VHSV-induced genes (VIGs) were first identified in rainbow trout (Oncorhynchus mykiss) and subsequently isolated in a variety of fish. Recent studies have shown that most VIGs have immunological functions against pathogenic infections. However, most research has focused on Vig1, such that our present understanding of ...

journal_title：Developmental and comparative immunology

authors： Yeh YC,Hsu YJ,Chen YM,Lin HY,Yang HL,Chen TY,Wang HC

更新日期：2014-03-01 00:00:00