The eukaryotic protein kinase superfamily of the necrotrophic fungal plant pathogen, Sclerotinia sclerotiorum.

Abstract:

:Protein kinases have been implicated in the regulation of many processes that guide pathogen development throughout the course of infection. A survey of the Sclerotinia sclerotiorum genome for genes encoding proteins containing the highly conserved eukaryotic protein kinase (ePK) domain, the largest protein kinase superfamily, revealed 92 S. sclerotiorum ePKs. This review examines the composition of the S. sclerotiorum ePKs based on conserved motifs within the ePK domain family, and relates this to orthologues found in other filamentous fungi and yeasts. The ePKs are also discussed in terms of their proposed role(s) in aspects of host pathogenesis, including the coordination of mycelial growth/development and deployment of pathogenicity determinants in response to environmental stimuli, nutrients and stress.

journal_name

Mol Plant Pathol

authors

Hegedus DD,Gerbrandt K,Coutu C

doi

10.1111/mpp.12321

subject

Has Abstract

pub_date

2016-05-01 00:00:00

pages

634-47

issue

4

eissn

1464-6722

issn

1364-3703

journal_volume

17

pub_type

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