Architecture of the Synaptophysin/Synaptobrevin Complex: Structural Evidence for an Entropic Clustering Function at the Synapse.

abstract：:Multifactorial lifestyle intervention is known to be more effective for ameliorating cognitive decline than single factor intervention; however, the effects of combining exercise with long-chain polyunsaturated fatty acids (LCPUFA) on the elderlies' cognitive function remain unclear. We conducted a randomised, single-...

journal_title：Scientific reports

authors： Tokuda H,Ito M,Sueyasu T,Sasaki H,Morita S,Kaneda Y,Rogi T,Kondo S,Kouzaki M,Tsukiura T,Shibata H

更新日期：2020-07-31 00:00:00

abstract：:Despite extensive efforts in studying radioactive aerosols, including the transmission of radionuclides in different chemical matrices throughout the body, the internal organ-specific radiation dose due to inhaled radioactive aerosols has largely relied on experimental deposition data and simplified human phantoms. Co...

journal_title：Scientific reports

authors： Talaat K,Xi J,Baldez P,Hecht A

更新日期：2019-11-25 00:00:00

abstract：:Osteosarcoma pulmonary metastases are typically treated with resection and/or chemotherapy. We hypothesize that stereotactic radiosurgery (SRS) can be an alternative to surgery that can achieve high rates of local control with limited toxicity. From January 2005 to December 2013, 73 patients who developed pulmonary me...

journal_title：Scientific reports

authors： Yu W,Liu Z,Tang L,Lin F,Yao Y,Shen Z

更新日期：2017-12-12 00:00:00

abstract：:First-generation adenovirus vectors (FG AdVs) are widely used in basic studies and gene therapy. However, virus-associated (VA) RNAs that act as small-interference RNAs are indeed transcribed from the vector genome. These VA RNAs can trigger the innate immune response. Moreover, VA RNAs are processed to functional vir...

journal_title：Scientific reports

authors： Maekawa A,Pei Z,Suzuki M,Fukuda H,Ono Y,Kondo S,Saito I,Kanegae Y

更新日期：2013-01-01 00:00:00

abstract：:TBX21 recode T-bet which is an important transcription factor that drives the Th1 immune response primarily by promoting expression of the interferon-gamma (IFNG) gene. Recent studies have shown that genetic variants in TBX21 and IFNG are connected with risk of systemic lupus erythematosus (SLE). The aim of the presen...

journal_title：Scientific reports

authors： Leng RX,Pan HF,Liu J,Yang XK,Zhang C,Tao SS,Wang DG,Li XM,Li XP,Yang W,Ye DQ

更新日期：2016-02-26 00:00:00

abstract：:Western North Pacific tropical cyclone (TC) activity is known to have a significant response to El Niño and Southern Oscillation (ENSO). Among the TC intensity classifications, "super typhoon", is widely used as a symbolic word for warning people about the potential for experiencing the most severe typhoon. This study...

journal_title：Scientific reports

authors： Kang NY,Kim D,Elsner JB

更新日期：2019-03-25 00:00:00

abstract：:Filth flies cause billions of dollars of losses annually to the animal production industry. Fluralaner is a relatively new pesticide currently sold for control of fleas, ticks, and mites on companion animals and poultry. We examined the efficacy of fluralaner against three species of filth flies. Insecticide-susceptib...

journal_title：Scientific reports

authors： Burgess ER,Geden CJ,Lohmeyer KH,King BH,Machtinger ET,Scott JG

更新日期：2020-07-07 00:00:00

abstract：:As we move, perceptual stability is crucial to successfully interact with our environment. Notably, the brain must update the locations of objects in space using extra-retinal signals. The vestibular system is a strong candidate as a source of information for spatial updating as it senses head motion. The ability to u...

journal_title：Scientific reports

authors： Mackrous I,Carriot J,Simoneau M

更新日期：2019-08-01 00:00:00

abstract：:We report on the synthesis and electrical properties of nine new alkylated silane self-assembled monolayers (SAMs) - (EtO)3Si(CH2)nN = CHPhX where n = 3 or 11 and X = 4-CF3, 3,5-CF3, 3-F-4-CF3, 4-F, or 2,3,4,5,6-F, and explore their rectification behavior in relation to their molecular structure. The electrical proper...

journal_title：Scientific reports

authors： Lamport ZA,Broadnax AD,Harrison D,Barth KJ,Mendenhall L,Hamilton CT,Guthold M,Thonhauser T,Welker ME,Jurchescu OD

更新日期：2016-11-29 00:00:00

abstract：:The growing prevalence of resistance to antibiotics motivates the search for new antibacterial agents. Antimicrobial peptides are a diverse class of well-studied membrane-active peptides which function as part of the innate host defence system, and form a promising avenue in antibiotic drug research. Some antimicrobia...

journal_title：Scientific reports

authors： Timmons PB,Hewage CM

更新日期：2020-07-02 00:00:00

abstract：:A GalNAc/Gal-specific lectin (CGL) from the edible mussel Crenomytilus grayanus has been demonstrated to exhibit antibacterial properties. However, the mechanism of immune modulation by CGL in mammalian cells remains unclear. Here, we demonstrated that CGL can activate immune responses in macrophages and in mice. In t...

journal_title：Scientific reports

authors： Chernikov OV,Wong WT,Li LH,Chikalovets IV,Molchanova VI,Wu SH,Liao JH,Hua KF

更新日期：2017-07-24 00:00:00

abstract：:Bringing oxygen atoms from infinite, passing equilibrium until short enough distances, we aim to reveal the 4f5d electron bonding property and its relevance to the peculiar physical properties within PrO2 based on both accounting for electron Coulomb repulsion and spin-orbit coupling effects in combination with Wannie...

journal_title：Scientific reports

authors： Zhang L,Meng J,Yao F,Liu X,Meng J,Zhang H

更新日期：2018-10-30 00:00:00

abstract：:Heavy metal contamination in water causes severe adverse effects on human health. Millions of tons of kernel shell are produced as waste from oil palm plantation every year. In this study, palm oil kernel shell (PKS), an agricultural waste is utilized as effective adsorbent for the removal of heavy metals, namely; Cr6...

journal_title：Scientific reports

authors： Baby R,Saifullah B,Hussein MZ

更新日期：2019-12-12 00:00:00

abstract：:The endoplasmic reticulum (ER) is a multi functional organelle and plays a crucial role in protein folding and lipid biosynthesis. The SEC59 gene encodes dolichol kinase, required for protein glycosylation in the ER. The mutation of sec59-1 caused a protein N-glycosylation defect mediated ER stress resulting in increa...

journal_title：Scientific reports

authors： William James A,Ravi C,Srinivasan M,Nachiappan V

更新日期：2019-10-09 00:00:00

abstract：:Maize rough dwarf virus (MRDV) is one of the main yield-limiting factors of maize in the Mediterranean. However, knowledge about the interactions between the agroecosystem and the virus-vector-host relationship continues to be limited. We used multi-model inference to test a landscape-scale approach together with vari...

journal_title：Scientific reports

authors： Clemente-Orta G,Albajes R,Batuecas I,Achon MA

更新日期：2021-01-13 00:00:00

abstract：:The goal of the current study was to develop an asymmetric guided bone regeneration (GBR) membrane benefiting from curcumin and aspirin. The membrane was prepared using electrospinning technique and then was physic-chemically characterized by the conventional methods. The release profile of aspirin from the prepared m...

journal_title：Scientific reports

authors： Ghavimi MA,Bani Shahabadi A,Jarolmasjed S,Memar MY,Maleki Dizaj S,Sharifi S

更新日期：2020-10-23 00:00:00

abstract：:Structural characteristics of the active layers in organic photovoltaic (OPV) devices play a critical role in charge generation, separation and transport. Here we report on morphology and structural control of p-DTS(FBTTh2)2:PC71BM films by means of thermal annealing and 1,8-diiodooctane (DIO) solvent additive process...

journal_title：Scientific reports

authors： Herath N,Das S,Keum JK,Zhu J,Kumar R,Ivanov IN,Sumpter BG,Browning JF,Xiao K,Gu G,Joshi P,Smith S,Lauter V

更新日期：2015-08-28 00:00:00

abstract：:In addition to its role in sister chromatid cohesion, genome stability and integrity, the cohesin complex is involved in gene transcription. Mutations in core cohesin subunits SMC1A, SMC3 and RAD21, or their regulators NIPBL and HDAC8, cause Cornelia de Lange syndrome (CdLS). Recent evidence reveals that gene expressi...

journal_title：Scientific reports

authors： Mannini L,C Lamaze F,Cucco F,Amato C,Quarantotti V,Rizzo IM,Krantz ID,Bilodeau S,Musio A

更新日期：2015-11-19 00:00:00

abstract：:We report the fabrication of flower-like CuO nanostructured surfaces via submerged photo-synthesis of crystallites (SPSC), which requires only UV illumination in neutral water. In this paper, we discuss the reaction mechanism of the photochemical formation of the SPSC-fabricated CuO nanostructures in detail based on s...

journal_title：Scientific reports

authors： Nishino F,Jeem M,Zhang L,Okamoto K,Okabe S,Watanabe S

更新日期：2017-04-21 00:00:00

abstract：:Recent studies have shown that L-proline is a natural osmoprotectant and an antioxidant to protect cells from injuries such as that caused by freezing and thawing in many species including plant, ram sperm and human endothelial cells. Nevertheless, this nontoxic cryoprotectant has not yet been applied to mammalian ooc...

journal_title：Scientific reports

authors： Zhang L,Xue X,Yan J,Yan LY,Jin XH,Zhu XH,He ZZ,Liu J,Li R,Qiao J

更新日期：2016-07-14 00:00:00

abstract：:Late endothelial progenitor cells (LEPCs) are derived from mononuclear cells (MNCs) and are thought to directly incorporate into blood vessels and differentiate into mature endothelial cells (ECs). Using transcriptome and proteome analysis, we identified distinctive LEPC profiles and found that Hedgehog-interacting pr...

journal_title：Scientific reports

authors： Lee BNR,Son YS,Lee D,Choi YJ,Kwon SM,Chang HK,Kim PH,Cho JY

更新日期：2017-09-29 00:00:00

abstract：:The ratio between the length of second and fourth digits (2D:4D) is a putative biomarker for prenatal testosterone and estrogen exposure. The aim of the study was to examine the association between 2D:4D and women's general and reproductive health. This analysis was conducted within a prospective pregnancy cohort stud...

journal_title：Scientific reports

authors： Tabachnik M,Sheiner E,Wainstock T

更新日期：2020-04-14 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： John SE,Opie NL,Wong YT,Rind GS,Ronayne SM,Gerboni G,Bauquier SH,O'Brien TJ,May CN,Grayden DB,Oxley TJ

更新日期：2018-11-27 00:00:00

abstract：:For patients with amyotrophic lateral sclerosis (ALS), the primary therapeutic goal is to minimize morbidity. Non-invasive ventilation improves survival. We aim to assess whether Magnetic Resonance Imaging (MRI) of the cervical spinal cord predicts the progression of respiratory disorders in ALS. Brain and spinal MRI ...

journal_title：Scientific reports

authors： Grolez G,Kyheng M,Lopes R,Moreau C,Timmerman K,Auger F,Kuchcinski G,Duhamel A,Jissendi-Tchofo P,Besson P,Laloux C,Petrault M,Devedjian JC,Pérez T,Pradat PF,Defebvre L,Bordet R,Danel-Brunaud V,Devos D

更新日期：2018-01-29 00:00:00

abstract：:Microalgae have great potential for the production of biofuels due to the ability of the organism to accumulate large quantities of storage lipids under stress conditions. Mitogen activated protein kinase (MAPK) signaling cascades are widely recognized for their role in stress response signal transduction in eukaryote...

journal_title：Scientific reports

authors： Yang A,Suh WI,Kang NK,Lee B,Chang YK

更新日期：2018-09-14 00:00:00

abstract：:Transgenic rice producing insecticidal proteins from Bacillus thuringiensis (Bt) could help protect the plants from damage by lepidopteran pests. However, one concern is the potential of Bt rice to harm non-target natural enemies, which play a vital role in pest control. In the present study, the potential effects of ...

journal_title：Scientific reports

authors： Tian JC,Romeis J,Liu K,Zhang FC,Zheng XS,Xu HX,Chen GH,He XC,Lu ZX

更新日期：2017-08-10 00:00:00

abstract：:We report the high susceptibility of several clinical isolates of Propionibacterium acnes from different sources (skin, bone, wound exudates, abscess or blood contamination) to the head-to-tail cyclized bacteriocin AS-48. This peptide is a feasible candidate for further pharmacological development against this bacteri...

journal_title：Scientific reports

authors： Cebrián R,Arévalo S,Rubiño S,Arias-Santiago S,Rojo MD,Montalbán-López M,Martínez-Bueno M,Valdivia E,Maqueda M

更新日期：2018-08-06 00:00:00

abstract：:The formation of OD (order-disorder) phases of the LPSO (long-period stacking ordered)-type in Mg-Al-RE (RE (rare earth) = Y, La, Ce, Nd, Sm, Dy, Ho, Er and Yb) ternary systems has been investigated for both as-solidified and annealed conditions. The OD phase is found to form in those systems with RE = Y, Nd, Sm, Dy, ...

journal_title：Scientific reports

authors： Kishida K,Yokobayashi H,Inui H

更新日期：2017-09-25 00:00:00

abstract：:Sex hormones may have a role in the pathophysiology of substance use disorders, as demonstrated by the association between testosterone and addictive behaviour in opioid dependence. Although opioid use has been found to suppress testosterone levels in men and women, the extent of this effect and how it relates to meth...

journal_title：Scientific reports

authors： Bawor M,Dennis BB,Samaan MC,Plater C,Worster A,Varenbut M,Daiter J,Marsh DC,Desai D,Steiner M,Anglin R,Coote M,Pare G,Thabane L,Samaan Z

更新日期：2014-08-26 00:00:00

abstract：:Black phosphorus (BP) has recently been rediscovered as a new and interesting two-dimensional material due to its unique electronic and optical properties. Here, we study the linear and nonlinear optical properties of BP flakes. We observe that both the linear and nonlinear optical properties are anisotropic and can b...

journal_title：Scientific reports

authors： Li D,Jussila H,Karvonen L,Ye G,Lipsanen H,Chen X,Sun Z

更新日期：2015-10-30 00:00:00