Effects of combining exercise with long-chain polyunsaturated fatty acid supplementation on cognitive function in the elderly: a randomised controlled trial.

abstract：:Long interspersed element-1 (LINE-1, L1) is a mobile genetic element comprising about 17% of the human genome. L1 utilizes an endonuclease to insert L1 cDNA into the target genomic DNA, which induces double-strand DNA breaks in the human genome and activates the DNA damage signaling pathway, resulting in the recruitme...

journal_title：Scientific reports

authors： Ariumi Y,Kawano K,Yasuda-Inoue M,Kuroki M,Fukuda H,Siddiqui R,Turelli P,Tateishi S

更新日期：2018-10-26 00:00:00

abstract：:The ability of wild animals to respond flexibly to anthropogenic environmental changes, including agriculture, is critical to survival in human-impacted habitats. Understanding use of human foods by wildlife can shed light on the acquisition of novel feeding habits and how animals respond to human-driven land-use chan...

journal_title：Scientific reports

authors： McLennan MR,Hockings KJ

更新日期：2014-08-05 00:00:00

abstract：:Single nucleotide variations (SNVs) can result in loss or gain of protein functional sites. We analyzed the effects of SNVs on enzyme active sites, ligand binding sites, and various types of post translational modification (PTM) sites. We found that, for most types of protein functional sites, the SNV pattern differs ...

journal_title：Scientific reports

authors： Pan Y,Yan C,Hu Y,Fan Y,Pan Q,Wan Q,Torcivia-Rodriguez J,Mazumder R

更新日期：2017-02-08 00:00:00

abstract：:Heteroplasmy is the existence of more than one mitochondrial DNA (mtDNA) variant within a cell. The evolutionary mechanisms of heteroplasmy are not fully understood, despite being a very common phenomenon. Here we combined heteroplasmy measurements using high throughput sequencing on green turtles (Chelonia mydas) wit...

journal_title：Scientific reports

authors： Tikochinski Y,Carreras C,Tikochinski G,Vilaça ST

更新日期：2020-01-14 00:00:00

abstract：:The new π-extended redox-active ligand with both TTF and triazole units, 6-(4,5-bis(propylthio)-1,3-dithiol-2-ylidene)-1H-[1,3]dithiolo[4',5':4,5]benzo [1,2-d] [1-3]triazole, has been successfully prepared. Based on the versatile ligand and Cu(tta)2 precursors (tta(-) = 4,4,4-trifluoro-1-(thiophen-2-yl)butane-1,3-dion...

journal_title：Scientific reports

authors： Cui L,Geng YF,Leong CF,Ma Q,D'Alessandro DM,Deng K,Zeng QD,Zuo JL

更新日期：2016-05-06 00:00:00

abstract：:A forest of the black coral Antipathella subpinnata was found from 52 to 80 m depth in three different sites at Tremiti Islands Marine Protected Area (MPA; Mediterranean Sea), with two of them hosting a monospecific forest on horizontal and vertical substrates. Colonies of A. subpinnata showed a mean density between 0...

journal_title：Scientific reports

authors： Chimienti G,De Padova D,Mossa M,Mastrototaro F

更新日期：2020-05-22 00:00:00

abstract：:The influenza A virus RNA polymerase cleaves the 5' end of host pre-mRNAs and uses the capped RNA fragments as primers for viral mRNA synthesis. We performed deep sequencing of the 5' ends of viral mRNAs from all genome segments transcribed in both human (A549) and mouse (M-1) cells infected with the influenza A/HongK...

journal_title：Scientific reports

authors： Sikora D,Rocheleau L,Brown EG,Pelchat M

更新日期：2014-08-26 00:00:00

abstract：:For translocated animals, behavioral competence may be key to post-release survival. However, monitoring behavior is typically limited to tracking movements or inferring behavior at a gross scale via collar-mounted sensors. Animal-bourne acoustic monitoring may provide a unique opportunity to monitor behavior at a fin...

journal_title：Scientific reports

authors： Yan X,Zhang H,Li D,Wu D,Zhou S,Sun M,Hu H,Liu X,Mou S,He S,Owen MA,Huang Y

更新日期：2019-03-26 00:00:00

abstract：:In many cancers, the establishment of a patient's future treatment regime often relies on histopathological assessment of tumor tissue specimens in order to determine the extent of the 'pathological response' to a given therapy. However, histopathological assessment of pathological response remains subjective. Here we...

journal_title：Scientific reports

authors： Patterson NH,Alabdulkarim B,Lazaris A,Thomas A,Marcinkiewicz MM,Gao ZH,Vermeulen PB,Chaurand P,Metrakos P

更新日期：2016-11-14 00:00:00

abstract：:Crimean-Congo hemorrhagic fever virus (CCHFV), a tick-borne bunyavirus, can cause a life-threatening hemorrhagic syndrome in humans but not in its animal host. The virus is widely distributed throughout southeastern Europe, the Middle East, Africa, and Asia. Disease management has proven difficult and there are no bro...

journal_title：Scientific reports

authors： Rodriguez SE,Cross RW,Fenton KA,Bente DA,Mire CE,Geisbert TW

更新日期：2019-05-23 00:00:00

abstract：:Ancestor microbes started colonizing inland habitats approximately 2.7 to 3.5 billion years ago. With some exceptions, the key physiological adaptations of microbiomes associated with marine-to-land transitions have remained elusive. This is essentially caused by the lack of suitable systems that depict changes in mic...

journal_title：Scientific reports

authors： Dini-Andreote F,van Elsas JD,Olff H,Salles JF

更新日期：2018-06-21 00:00:00

abstract：:Protein tyrosine kinase (PTK) activity has been implicated in pro-inflammatory gene expression following tumor necrosis factor-α (TNF-α) or interkeukin-1β (IL-1β) stimulation. However, the identity of responsible PTK(s) in cytokine signaling have not been elucidated. To evaluate which PTK is critical to promote the cy...

journal_title：Scientific reports

authors： Murphy JM,Jeong K,Rodriguez YAR,Kim JH,Ahn EE,Lim SS

更新日期：2019-05-20 00:00:00

abstract：:The changes of balance control mechanism caused by lumbar disc herniation (LDH) has not been well understood. This study aimed to investigate the effects of LDH on the balance control during standing on sloped surfaces. Ten patients with LDH and 10 gender- and age-matched healthy subjects were instructed to stand quie...

journal_title：Scientific reports

authors： Li J,Zhang Y,Song S,Hou Y,Hong Y,Yue S,Li K

更新日期：2020-02-03 00:00:00

abstract：:Biclustering algorithms, which aim to provide an effective and efficient way to analyze gene expression data by finding a group of genes with trend-preserving expression patterns under certain conditions, have been widely developed since Morgan et al. pioneered a work about partitioning a data matrix into submatrices ...

journal_title：Scientific reports

authors： Wang Z,Li G,Robinson RW,Huang X

更新日期：2016-03-22 00:00:00

abstract：:Medical image segmentation is an important tool for current clinical applications. It is the backbone of numerous clinical diagnosis methods, oncological treatments and computer-integrated surgeries. A new class of machine learning algorithm, deep learning algorithms, outperforms the results of classical segmentation ...

journal_title：Scientific reports

authors： Renard F,Guedria S,Palma N,Vuillerme N

更新日期：2020-08-13 00:00:00

abstract：:Greenhouse and field studies were conducted to provide a reference for pre-emergence (PRE) application of isoxaflutole on maize in China. In greenhouse study, the isoxaflutole PRE application at 30 g active ingredient (a.i.) ha-1 could effectively control large numbers of weeds, especially some large-seeded broadleave...

journal_title：Scientific reports

authors： Zhao N,Zuo L,Li W,Guo W,Liu W,Wang J

更新日期：2017-10-04 00:00:00

abstract：:Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that act as ligand-activated transcription factors. PPAR agonists have well-documented anti-inflammatory and neuroprotective roles in the central nervous system. Recent evidence suggests that PPAR agonists are attractive therapeutic agen...

journal_title：Scientific reports

authors： Warden A,Truitt J,Merriman M,Ponomareva O,Jameson K,Ferguson LB,Mayfield RD,Harris RA

更新日期：2016-06-10 00:00:00

abstract：:Transposable elements (TEs) are genomic sequences that can move, multiply, and often form sizable fractions of vertebrate genomes. Fish belong to a unique group of vertebrates, since their karyotypes and genome sizes are more diverse and complex, with probably higher diversity and evolution specificity of TE. To inves...

journal_title：Scientific reports

authors： Shao F,Han M,Peng Z

更新日期：2019-10-28 00:00:00

abstract：:We compared the effects of 12-week programs of resistance training (RT), high-intensity interval aerobic training (HIAT), and moderate-intensity continuous aerobic training (MICT). The primary goal was to evaluate the therapeutic effects of the exercise modalities for the management of nonalcoholic fatty liver disease...

journal_title：Scientific reports

authors： Oh S,So R,Shida T,Matsuo T,Kim B,Akiyama K,Isobe T,Okamoto Y,Tanaka K,Shoda J

更新日期：2017-02-22 00:00:00

abstract：:AMP-activated protein kinase (AMPK) is a key sensor and regulator of glucose metabolism. Here, we demonstrated that shizukaol F, a natural compound isolated from Chloranthus japonicus, can activate AMPK and modulate glucose metabolism both in vitro and in vivo. Shizukaol F increased glucose uptake in differentiated C2...

journal_title：Scientific reports

authors： Hu R,Yan H,Fei X,Liu H,Wu J

更新日期：2017-04-10 00:00:00

abstract：:Excision repair cross-complementing 1 (ERCC1) gene encodes ERCC1 protein, which is mainly responsible for the repair of DNA damage in different diseases including coronary artery atherosclerosis by acting as a rate-limiting element in nucleotide excision repair (NER). Using a three-stage case-control study with 3037 c...

journal_title：Scientific reports

authors： Zhang S,Wang XB,Han YD,Xiong CL,Zhou Y,Wang C,Liu ZJ,Yang N,Zheng F

更新日期：2017-07-25 00:00:00

abstract：:The rare-earth monopnictide family is attracting an intense current interest driven by its unusual extreme magnetoresistance (XMR) property and the potential presence of topologically non-trivial surface states. The experimental observation of non-trivial surface states in this family of materials are not ubiquitous. ...

journal_title：Scientific reports

authors： Hosen MM,Dhakal G,Wang B,Poudel N,Singh B,Dimitri K,Kabir F,Sims C,Regmi S,Neff W,Sarkar AB,Agarwal A,Murray D,Weickert F,Gofryk K,Pavlosiuk O,Wiśniewski P,Kaczorowski D,Bansil A,Neupane M

更新日期：2020-07-31 00:00:00

abstract：:Enoyl-acyl carrier protein reductase (ENR) catalyzes the last reduction step in the bacterial type II fatty acid biosynthesis cycle. ENRs include FabI, FabL, FabL2, FabK, and FabV. Previously, we reported a unique triclosan (TCL) resistant ENR homolog that was predominant in obligate intracellular pathogenic bacteria ...

journal_title：Scientific reports

authors： Khan R,Zeb A,Choi K,Lee G,Lee KW,Lee SW

更新日期：2019-10-28 00:00:00

abstract：:Enhancement of endogenous neurogenesis after ischemic stroke may improve functional recovery. We previously demonstrated that medium B, which is a combination with epidermal growth factor (EGF) and fibronectin, can promote neural stem/progenitor cell (NSPC) proliferation and migration. Here, we showed that medium B pr...

journal_title：Scientific reports

authors： Chen YA,Tsai YC,Chen YD,Liu DZ,Young TH,Tsai LK

更新日期：2020-04-20 00:00:00

abstract：:Today's electronic devices are fabricated using highly toxic materials and processes which limits their applications in environmental sensing applications and mandates complex encapsulation methods in biological and medical applications. This paper proposes a fully resorbable high density bio-compatible and environmen...

journal_title：Scientific reports

authors： Yong J,Hassan B,Liang Y,Ganesan K,Rajasekharan R,Evans R,Egan G,Kavehei O,Li J,Chana G,Nasr B,Skafidas E

更新日期：2017-11-07 00:00:00

abstract：:Inflammatory processes have been implicated in the pathogenesis of Parkinson's disease (PD), including the development of PD-associated cognitive impairment. Whether genetic variants of inflammatory cytokine genes influence the risk of cognitive impairment in PD is unknown. In this study, we investigated single nucleo...

journal_title：Scientific reports

authors： Liu Z,Guo J,Wang Y,Li K,Kang J,Wei Y,Sun Q,Xu Q,Xu C,Yan X,Tang B

更新日期：2016-02-02 00:00:00

abstract：:Different marine habitats are characterised by different soundscapes. How or which differences may be representative of the habitat characteristics and/or community structure remains however to be explored. A growing project in passive acoustics is to find a way to use soundscapes to have information on the habitat an...

journal_title：Scientific reports

authors： Bertucci F,Parmentier E,Lecellier G,Hawkins AD,Lecchini D

更新日期：2016-09-15 00:00:00

abstract：:Fragmentation is a major driver of ecosystem degradation, reducing the capacity of habitats to provide many important ecosystem services. Mangrove ecosystem services, such as erosion prevention, shoreline protection and mitigation of climate change (through carbon sequestration), depend on the size and arrangement of ...

journal_title：Scientific reports

authors： Bryan-Brown DN,Connolly RM,Richards DR,Adame F,Friess DA,Brown CJ

更新日期：2020-04-28 00:00:00

abstract：:The ability to harvest thermal energy and manipulate heat fluxes has recently attracted a great deal of research interest because this is critical to achieve efficient solar-to-thermal energy conversion in the technology of concentrated solar thermal collectors. Thermal metamaterials with engineered thermal conduction...

journal_title：Scientific reports

authors： Chen F,Lei DY

更新日期：2015-06-25 00:00:00

abstract：:Reprogramming of somatic cells has become a versatile tool for biomedical research and for regenerative medicine. In the current study, we show that manipulating alternative splicing (AS) is a highly potent strategy to produce cells for therapeutic applications. We demonstrate that silencing of hTAF4-TAFH activity of ...

journal_title：Scientific reports

authors： Kazantseva J,Sadam H,Neuman T,Palm K

更新日期：2016-08-08 00:00:00