A geometric correction scheme for spatial leakage effects in MEG/EEG seed-based functional connectivity mapping.

Abstract:

:Spatial leakage effects are particularly confounding for seed-based investigations of brain networks using source-level electroencephalography (EEG) or magnetoencephalography (MEG). Various methods designed to avoid this issue have been introduced but are limited to particular assumptions about its temporal characteristics. Here, we investigate the usefulness of a model-based geometric correction scheme (GCS) to suppress spatial leakage emanating from the seed location. We analyze its properties theoretically and then assess potential advantages and limitations with simulated and experimental MEG data (resting state and auditory-motor task). To do so, we apply Minimum Norm Estimation (MNE) for source reconstruction and use variation of error parameters, statistical gauging of spatial leakage correction and comparison with signal orthogonalization. Results show that the GCS has a local (i.e., near the seed) effect only, in line with the geometry of MNE spatial leakage, and is able to map spatially all types of brain interactions, including linear correlations eliminated after signal orthogonalization. Furthermore, it is robust against the introduction of forward model errors. On the other hand, the GCS can be affected by local overcorrection effects and seed mislocation. These issues arise with signal orthogonalization too, although significantly less extensively, so the two approaches complement each other. The GCS thus appears to be a valuable addition to the spatial leakage correction toolkits for seed-based FC analyses in source-projected MEG/EEG data.

journal_name

Hum Brain Mapp

journal_title

Human brain mapping

authors

Wens V,Marty B,Mary A,Bourguignon M,Op de Beeck M,Goldman S,Van Bogaert P,Peigneux P,De Tiège X

doi

10.1002/hbm.22943

subject

Has Abstract

pub_date

2015-11-01 00:00:00

pages

4604-21

issue

11

eissn

1065-9471

issn

1097-0193

journal_volume

36

pub_type

杂志文章
  • Effects of aripiprazole and haloperidol on neural activation during a simple motor task in healthy individuals: A functional MRI study.

    abstract::The dopaminergic system plays a key role in motor function and motor abnormalities have been shown to be a specific feature of psychosis. Due to their dopaminergic action, antipsychotic drugs may be expected to modulate motor function, but the precise effects of these drugs on motor function remain unclear. We carried...

    journal_title:Human brain mapping

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/hbm.23485

    authors: Goozee R,O'Daly O,Handley R,Reis Marques T,Taylor H,McQueen G,Hubbard K,Pariante C,Mondelli V,Reinders AA,Dazzan P

    更新日期:2017-04-01 00:00:00

  • Abnormal neural response to phonological working memory demands in persistent developmental stuttering.

    abstract::Persistent developmental stuttering is a neurological disorder that commonly manifests as a motor problem. Cognitive theories, however, hold that poorly developed cognitive skills are the origins of stuttering. Working memory (WM), a multicomponent cognitive system that mediates information maintenance and manipulatio...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.24366

    authors: Yang Y,Jia F,Fox PT,Siok WT,Tan LH

    更新日期:2019-01-01 00:00:00

  • Stochastic dynamic causal modeling of working memory connections in cocaine dependence.

    abstract::Although reduced working memory brain activation has been reported in several brain regions of cocaine-dependent subjects compared with controls, very little is known about whether there is altered connectivity of working memory pathways in cocaine dependence. This study addresses this issue by using functional magnet...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.22212

    authors: Ma L,Steinberg JL,Hasan KM,Narayana PA,Kramer LA,Moeller FG

    更新日期:2014-03-01 00:00:00

  • Dynamic functional network reconfiguration underlying the pathophysiology of schizophrenia and autism spectrum disorder.

    abstract::The dynamics of the human brain span multiple spatial scales, from connectivity associated with a specific region/network to the global organization, each representing different brain mechanisms. Yet brain reconfigurations at different spatial scales are seldom explored and whether they are associated with the neural ...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.25205

    authors: Fu Z,Sui J,Turner JA,Du Y,Assaf M,Pearlson GD,Calhoun VD

    更新日期:2021-01-01 00:00:00

  • Dopaminergic system and dream recall: An MRI study in Parkinson's disease patients.

    abstract::We investigated the role of the dopamine system [i.e., subcortical-medial prefrontal cortex (mPFC) network] in dreaming, by studying patients with Parkinson's Disease (PD) as a model of altered dopaminergic transmission. Subcortical volumes and cortical thickness were extracted by 3T-MR images of 27 PD patients and 27...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.23095

    authors: De Gennaro L,Lanteri O,Piras F,Scarpelli S,Assogna F,Ferrara M,Caltagirone C,Spalletta G

    更新日期:2016-03-01 00:00:00

  • Reconstruction of extended cortical sources for EEG and MEG based on a Monte-Carlo-Markov-chain estimator.

    abstract::A new procedure to model extended cortical sources from EEG and MEG recordings based on a probabilistic approach is presented. The method (SPMECS) was implemented within the framework of maximum likelihood estimators. Neuronal activity generating EEG or MEG signals was characterized by the number of sources and their ...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.10079

    authors: Kincses WE,Braun C,Kaiser S,Grodd W,Ackermann H,Mathiak K

    更新日期:2003-02-01 00:00:00

  • Antihistamine induced blood oxygenation level dependent response changes related to visual processes during sensori-motor performance.

    abstract::The histaminergic involvement in selective processes underlying its role in human sensori-motor performance is largely unknown. Recently, selective effects of central H₁-inverse agonism on sensory visual processes were observed in electrophysiological--but not behavioral data; a discrepancy suggested to result from sp...

    journal_title:Human brain mapping

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/hbm.22387

    authors: van Ruitenbeek P,Vermeeren A,Mehta MA,Drexler EI,Riedel WJ

    更新日期:2014-07-01 00:00:00

  • A Comparison of the neural correlates that underlie rule-based and information-integration category learning.

    abstract::The influential competition between verbal and implicit systems (COVIS) model proposes that category learning is driven by two competing neural systems-an explicit, verbal, system, and a procedural-based, implicit, system. In the current fMRI study, participants learned either a conjunctive, rule-based (RB), category ...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.23259

    authors: Carpenter KL,Wills AJ,Benattayallah A,Milton F

    更新日期:2016-10-01 00:00:00

  • Differential activation of the human trigeminal nuclear complex by noxious and non-noxious orofacial stimulation.

    abstract::There is good evidence from animal studies for segregation in the processing of non-nociceptive and nociceptive information within the trigeminal brainstem sensory nuclear complex. However, it remains unknown whether a similar segregation occurs in humans, and a recent tract tracing study suggests that this segregatio...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.20805

    authors: Nash PG,Macefield VG,Klineberg IJ,Murray GM,Henderson LA

    更新日期:2009-11-01 00:00:00

  • Frontal and posterior cingulate metabolic impairment in the behavioral variant of frontotemporal dementia with impaired autonoetic consciousness.

    abstract::Although memory dysfunction is not a prominent feature of the behavioral variant of frontotemporal dementia (bv-FTD), there is evidence of specific deficits of episodic memory in these patients. They also have problems monitoring their memory performance. The objective of the present study was to explore the ability t...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.21282

    authors: Bastin C,Feyers D,Souchay C,Guillaume B,Pepin JL,Lemaire C,Degueldre C,Collette F,Salmon E

    更新日期:2012-06-01 00:00:00

  • Heritability of regional and global brain structure at the onset of puberty: a magnetic resonance imaging study in 9-year-old twin pairs.

    abstract::Puberty represents the phase of sexual maturity, signaling the change from childhood into adulthood. During childhood and adolescence, prominent changes take place in the brain. Recently, variation in frontal, temporal, and parietal areas was found to be under varying genetic control between 5 and 19 years of age. How...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.20660

    authors: Peper JS,Schnack HG,Brouwer RM,Van Baal GC,Pjetri E,Székely E,van Leeuwen M,van den Berg SM,Collins DL,Evans AC,Boomsma DI,Kahn RS,Hulshoff Pol HE

    更新日期:2009-07-01 00:00:00

  • Image registration using a symmetric prior--in three dimensions.

    abstract::This paper describes a Bayesian method for three-dimensional registration of brain images. A finite element approach is used to obtain a maximum a posteriori estimate of the deformation field at every voxel of a template volume. The priors used by the MAP estimate penalize unlikely deformations and enforce a continuou...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0193(200004)9:4<212::aid-hbm3>3

    authors: Ashburner J,Andersson JL,Friston KJ

    更新日期:2000-04-01 00:00:00

  • Combined neuroimaging and gene expression analysis of the genetic basis of brain plasticity indicates across species homology.

    abstract::Brain plasticity and memory formation depend on the expression of a large number of genes. This relationship had been studied using several experimental approaches and researchers have identified genes regulating plasticity through a variety of mechanisms. Despite this effort, a great deal remains unknown regarding th...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.22592

    authors: Dinai Y,Wolf L,Assaf Y

    更新日期:2014-12-01 00:00:00

  • Granger causal influence predicts BOLD activity levels in the default mode network.

    abstract::Although the brain areas in the default-mode network (DMN) act in a coordinated way during rest, the activity levels in the individual areas of the DMN are highly heterogeneous. The relation between the activity levels and the pattern of causal interaction among the DMN areas remains unknown. In the present fMRI study...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.21065

    authors: Jiao Q,Lu G,Zhang Z,Zhong Y,Wang Z,Guo Y,Li K,Ding M,Liu Y

    更新日期:2011-01-01 00:00:00

  • Private but not social information validity modulates social conformity bias.

    abstract::It is well established that human behaviors are susceptible to others' opinions. However, optimal decision theory mandates choices be made upon the estimated validities of different information sources and little is known about whether and how people could wean themselves off social conformity bias, especially when th...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.24536

    authors: Li L,Li KK,Li J

    更新日期:2019-06-01 00:00:00

  • Impaired structural connectivity between dorsal attention network and pulvinar mediates the impact of premature birth on adult visual-spatial abilities.

    abstract::The dorsal attention network (DAN), including frontal eye fields and posterior parietal cortices, and its link with the posterior thalamus, contribute to visual-spatial abilities. Very premature birth impairs both visual-spatial abilities and cortico-thalamic structural connectivity. We hypothesized that impaired stru...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.24685

    authors: Berndt M,Bäuml JG,Menegaux A,Meng C,Daamen M,Baumann N,Zimmer C,Boecker H,Bartmann P,Wolke D,Sorg C

    更新日期:2019-10-01 00:00:00

  • Neural signature of inattentional deafness.

    abstract::Inattentional deafness is the failure to hear otherwise audible sounds (usually alarms) that may occur under high workload conditions. One potential cause for its occurrence could be an attentional bottleneck that occurs when task demands are high, resulting in lack of resources for processing of additional tasks. In ...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.23735

    authors: Durantin G,Dehais F,Gonthier N,Terzibas C,Callan DE

    更新日期:2017-11-01 00:00:00

  • White matter tract myelin maturation and its association with general psychopathology in adolescence and early adulthood.

    abstract::Adolescence is a time period associated with marked brain maturation that coincides with an enhanced risk for onset of psychiatric disorder. White matter tract myelination, a process that continues to unfold throughout adolescence, is reported to be abnormal in several psychiatric disorders. Here, we ask whether psych...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.24842

    authors: Vanes LD,Moutoussis M,Ziegler G,Goodyer IM,Fonagy P,Jones PB,Bullmore ET,NSPN Consortium.,Dolan RJ

    更新日期:2020-02-15 00:00:00

  • Toward a "treadmill test" for cognition: Improved prediction of general cognitive ability from the task activated brain.

    abstract::General cognitive ability (GCA) refers to a trait-like ability that contributes to performance across diverse cognitive tasks. Identifying brain-based markers of GCA has been a longstanding goal of cognitive and clinical neuroscience. Recently, predictive modeling methods have emerged that build whole-brain, distribut...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.25007

    authors: Sripada C,Angstadt M,Rutherford S,Taxali A,Shedden K

    更新日期:2020-08-15 00:00:00

  • Childhood maltreatment is associated with an automatic negative emotion processing bias in the amygdala.

    abstract:UNLABELLED:Major depression has been repeatedly associated with amygdala hyper-responsiveness to negative (but not positive) facial expressions at early, automatic stages of emotion processing using subliminally presented stimuli. However, it is not clear whether this "limbic bias" is a correlate of depression or repre...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.22112

    authors: Dannlowski U,Kugel H,Huber F,Stuhrmann A,Redlich R,Grotegerd D,Dohm K,Sehlmeyer C,Konrad C,Baune BT,Arolt V,Heindel W,Zwitserlood P,Suslow T

    更新日期:2013-11-01 00:00:00

  • Relationship between structural and functional connectivity change across the adult lifespan: A longitudinal investigation.

    abstract::Extensive efforts are devoted to understand the functional (FC) and structural connections (SC) of the brain. FC is usually measured by functional magnetic resonance imaging (fMRI), and conceptualized as degree of synchronicity in brain activity between different regions. SC is typically indexed by measures of white m...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.23403

    authors: Fjell AM,Sneve MH,Grydeland H,Storsve AB,Amlien IK,Yendiki A,Walhovd KB

    更新日期:2017-01-01 00:00:00

  • Alterations in functional activation in euthymic bipolar disorder and schizophrenia during a working memory task.

    abstract::Dysfunctions in prefrontal cortical networks are thought to underlie working memory (WM) impairments consistently observed in both subjects with bipolar disorder and schizophrenia. It remains unclear, however, whether patterns of WM-related hemodynamic responses are similar in bipolar and schizophrenia subjects compar...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.20820

    authors: Hamilton LS,Altshuler LL,Townsend J,Bookheimer SY,Phillips OR,Fischer J,Woods RP,Mazziotta JC,Toga AW,Nuechterlein KH,Narr KL

    更新日期:2009-12-01 00:00:00

  • Real-time strategy video game experience and structural connectivity - A diffusion tensor imaging study.

    abstract::Experienced video game players exhibit superior performance in visuospatial cognition when compared to non-players. However, very little is known about the relation between video game experience and structural brain plasticity. To address this issue, a direct comparison of the white matter brain structure in RTS (real...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.24208

    authors: Kowalczyk N,Shi F,Magnuski M,Skorko M,Dobrowolski P,Kossowski B,Marchewka A,Bielecki M,Kossut M,Brzezicka A

    更新日期:2018-09-01 00:00:00

  • Multimodal fusion of structural and functional brain imaging in depression using linked independent component analysis.

    abstract::Previous structural and functional neuroimaging studies have implicated distributed brain regions and networks in depression. However, there are no robust imaging biomarkers that are specific to depression, which may be due to clinical heterogeneity and neurobiological complexity. A dimensional approach and fusion of ...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.24802

    authors: Maglanoc LA,Kaufmann T,Jonassen R,Hilland E,Beck D,Landrø NI,Westlye LT

    更新日期:2020-01-01 00:00:00

  • fMRI identifies the right inferior frontal cortex as the brain region where time interval processing is altered by negative emotional arousal.

    abstract::The reason why human beings are inclined to overestimate the duration of highly arousing negative events remains enigmatic. The issue about what neurocognitive mechanisms and neural structures support the connection between time perception and emotion was addressed here by an event-related neuroimaging study involving...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.22680

    authors: Pfeuty M,Dilharreguy B,Gerlier L,Allard M

    更新日期:2015-03-01 00:00:00

  • Gray matter correlates of dopaminergic degeneration in Parkinson's disease: A hybrid PET/MR study using (18) F-FP-CIT.

    abstract::Dopaminergic degeneration is a hallmark of Parkinson's disease (PD), which causes various symptoms affected by corticostriatal circuits. So far, the relationship between cortical changes and dopamine loss in the striatum is unclear. Here, we evaluate the gray matter (GM) changes in accordance with striatal dopaminergi...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.23130

    authors: Choi H,Cheon GJ,Kim HJ,Choi SH,Kim YI,Kang KW,Chung JK,Kim EE,Lee DS

    更新日期:2016-05-01 00:00:00

  • The inferior occipital gyrus is a major cortical source of the face-evoked N170: Evidence from simultaneous scalp and intracerebral human recordings.

    abstract::The sudden onset of a face image leads to a prominent face-selective response in human scalp electroencephalographic (EEG) recordings, peaking 170 ms after stimulus onset at occipito-temporal (OT) scalp sites: the N170 (or M170 in magnetoencephalography). According to a widely held view, the main cortical source of th...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.24455

    authors: Jacques C,Jonas J,Maillard L,Colnat-Coulbois S,Koessler L,Rossion B

    更新日期:2019-04-01 00:00:00

  • Automated quality assurance routines for fMRI data applied to a multicenter study.

    abstract::Standard procedures to achieve quality assessment (QA) of functional magnetic resonance imaging (fMRI) data are of great importance. A standardized and fully automated procedure for QA is presented that allows for classification of data quality and the detection of artifacts by inspecting temporal variations. The appl...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.20096

    authors: Stöcker T,Schneider F,Klein M,Habel U,Kellermann T,Zilles K,Shah NJ

    更新日期:2005-06-01 00:00:00

  • The effect of ageing on fMRI: Correction for the confounding effects of vascular reactivity evaluated by joint fMRI and MEG in 335 adults.

    abstract::In functional magnetic resonance imaging (fMRI) research one is typically interested in neural activity. However, the blood-oxygenation level-dependent (BOLD) signal is a composite of both neural and vascular activity. As factors such as age or medication may alter vascular function, it is essential to account for cha...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.22768

    authors: Tsvetanov KA,Henson RN,Tyler LK,Davis SW,Shafto MA,Taylor JR,Williams N,Cam-Can,Rowe JB

    更新日期:2015-06-01 00:00:00

  • Modulating functional connectivity patterns and topological functional organization of the human brain with transcranial direct current stimulation.

    abstract::Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation technique that alters cortical excitability and activity in a polarity-dependent way. Stimulation for few minutes has been shown to induce plastic alterations of cortical excitability and to improve cognitive performance. These effects m...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.21104

    authors: Polanía R,Nitsche MA,Paulus W

    更新日期:2011-08-01 00:00:00