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Making a Choice: How Cadherin Switching Controls Cell Migration.

Abstract：

:Cells that undergo epithelial-to-mesenchymal transitions (EMTs) commonly switch from expressing E-cadherin to N-cadherin. But why this occurs is not well understood. In the current issue of Developmental Cell, Scarpa et al. (2015) identify a reason: cadherin switching controls Rac signaling to determine how cell locomotion is regulated by contact.

journal_name

Dev Cell

journal_title

Developmental cell

authors

Priya R,Yap AS

doi

10.1016/j.devcel.2015.08.002

subject

Has Abstract

pub_date

2015-08-24 00:00:00

pages

383-4

issue

4

eissn

1534-5807

issn

1878-1551

pii

S1534-5807(15)00516-X

journal_volume

34

pub_type

评论,杂志文章

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