Fabrication and characterization of electrospun zein/Ag nanocomposite mats for wound dressing applications.

Abstract:

:Wound dressing is a very important factor in the process of wound healing as proper wound care can accelerate the recovery of the wound. In this study, zein nanofibrous mats with fiber diameters around 350-500 nm were prepared by electrospinning and silver (Ag) nanoparticles around 20 nm were concurrently synthesized in situ into the mats. The electrospun nanofibers were characterized by Field Emission-Scanning Electron Microscopy (FE-SEM), Transmission Electron Microscopy (TEM), Fourier Transform Infrared Spectroscopy (FTIR) and X-ray photoelectron spectroscopy (XPS) analysis. Cell viability and activity of fibroblasts cells in zein/Ag mats were also evaluated and results demonstrated good cytocompatibility and attachment of cells on the composite nanofibers. Also, the bactericidal activity of the fabricated mats against gram-positive Staphylococcus aureus (S. aureus) and gram-negative Escherichia coli (E. coli) was investigated via zone of inhibition test and results showed high anti-bacterial performance.

journal_name

Int J Biol Macromol

authors

Dashdorj U,Reyes MK,Unnithan AR,Tiwari AP,Tumurbaatar B,Park CH,Kim CS

doi

10.1016/j.ijbiomac.2015.06.026

subject

Has Abstract

pub_date

2015-09-01 00:00:00

pages

1-7

eissn

0141-8130

issn

1879-0003

pii

S0141-8130(15)00429-8

journal_volume

80

pub_type

杂志文章
  • Indole-3-acetic acid/diol based pH-sensitive biological macromolecule for antibacterial, antifungal and antioxidant applications.

    abstract::Indole-3-acetic acid (IAA)/diol based pH-sensitive biopolymeric hydrogels with tunable biological properties (cytotoxicity, anti-oxidant and anti-fungal) have been synthesized via condensation polymerization. The present study focused on the synthesis of heterocyclic hydrogel using citric acid (CA), indole-3-acetic ac...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2016.11.068

    authors: G C,D S F,S S,M S,S G

    更新日期:2017-02-01 00:00:00

  • Cyclodextrin based ternary system of modafinil: Effect of trimethyl chitosan and polyvinylpyrrolidone as complexing agents.

    abstract::Modafinil is an approved drug for the treatment of narcolepsy and have a strong market presence in many countries. The drug is widely consumed for off-label uses and currently listed as a restricted drug. Modafinil has very low water solubility. To enhance the aqueous solubility of modafinil by the formation of a tern...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2015.11.075

    authors: Patel P,Agrawal YK,Sarvaiya J

    更新日期:2016-03-01 00:00:00

  • Phosphorylated serine clusters of phosvitin plays a crucial role in the regulatory mineralization.

    abstract::Phosphorylation of phosvitin has been proved to play an important role in the mineralization, but the active region of phosvitin is still not known yet. Four phosvitin phosphopeptides (PPPs) were obtained after separating from ion exchange column and desalting from gel filtration, and named as PPP0, PPP1, PPP3 and PPP...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2018.04.130

    authors: Zhang X,Huang X,Ma M

    更新日期:2018-08-01 00:00:00

  • An immune-responsive PGRP-S1 regulates the expression of antibacterial peptide genes in diamondback moth, Plutella xylostella (L.).

    abstract::Peptidoglycan recognition proteins (PGRPs) are family of pattern recognition receptors (PRRs) and triggers the innate immune system (IIS) against the microbial infection. Although PGRPs have been intensively studied in model insects, they remain uncharacterized in most of the non-model insects. Here, we cloned and cha...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2019.09.081

    authors: Zhang Z,Kong J,De Mandal S,Li S,Zheng Z,Jin F,Xu X

    更新日期:2020-01-01 00:00:00

  • Study of the cell responses in tantalum carbide nanoparticles-enriched polysaccharide composite hydrogel.

    abstract::Salecan is a linear microbial polysaccharide obtained from the fermentation of Agrobacterium sp. ZX09. Salecan is suitable for the preparation of hydrogels for biomedical applications, given its prominent physicochemical and biological properties. Herein, we described a novel microwave-assisted polymerized composite h...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2019.05.191

    authors: Hu X,Wang Y,Xu M

    更新日期:2019-08-15 00:00:00

  • Bioconversion of crude glycerol to polyhydroxyalkanoate by Bacillus thuringiensis under non-limiting nitrogen conditions.

    abstract::Glycerol has emerged as a cheap waste material due to blooming biodiesel manufacturing units worldwide. The need is to exploit the crude glycerol (CG) to produce useful products such as polyhydroxyalkanoate (PHA). Bacillus thuringiensis EGU45 was found to produce 1.5-3.5 gP HA L(-1) from feed containing 1-10% CG (vv(-...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2015.03.046

    authors: Kumar P,Ray S,Patel SK,Lee JK,Kalia VC

    更新日期:2015-01-01 00:00:00

  • Sappanone A prevents hypoxia-induced injury in PC-12 cells by down-regulation of miR-15a.

    abstract:OBJECTIVE:We aimed to explore the effect of Sappanone A on neurologic damage induced by hypoxia. METHODS:PC-12 cells were pre-treated with Sappanone A and were simulated by hypoxia. miRNA transfection was performed to overexpress or suppress the expression of miR-15a in PC-12 cells. Cell viability, apoptosis, migratio...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2018.11.002

    authors: Kang C,Gao J,Kang M,Liu X,Fu Y,Wang L

    更新日期:2019-02-15 00:00:00

  • Chaperone-like activity of heme group against amyloid-like fibril formation by hen egg ovalbumin: possible mechanism of action.

    abstract::It is well accepted that porphyrins related to heme, are effectively able to act as pharmaceutical. For instance, they were found to interfere with the aggregation of beta-amyloid peptide. In present study, the influence of heme concentration on the amyloid-type aggregation of ovalbumin was investigated. We provided e...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2008.10.011

    authors: Khodarahmi R,Soori H,Karimi SA

    更新日期:2009-01-01 00:00:00

  • [HNMP]HSO4 catalyzed synthesis of selenized polysaccharide and its immunomodulatory effect on RAW264.7 cells via MAPKs pathway.

    abstract::In this paper, selenized Artemisia sphaerocephala polysaccharides (SePAS) were obtained through employing N-methyl-2-pyrrolidone hydrosulfate as catalyst, which showed a maximum Se content enhanced to 8744 μg/g. FT-IR, 1D/2D NMR, X-ray photoelectron spectroscopy (XPS) and size-exclusion chromatograph analysis exhibite...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2020.05.261

    authors: Li R,Qin X,Liu S,Zhang X,Zeng X,Guo H,Wang T,Zhang Y,Zhang J,Zhang J,Wang J

    更新日期:2020-10-01 00:00:00

  • Physicochemical and drug release characteristics of acetylated starches of five Lagenaria siceraria cultivars.

    abstract::Modified starches play a crucial role in the pharmaceutical industries in controlling the drug release at a pre-determined rate. The effect of acetylation on the physicochemical and drug release characteristics of the starches from five different Indian L. siceraria cultivars was investigated. Starches isolated from t...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2014.10.007

    authors: Kulkarni SD,Sinha BN,Kumar KJ

    更新日期:2015-01-01 00:00:00

  • Synthesis and characterization of stable and biological active chitin-based polyurethane elastomers.

    abstract::In this work, the preparation of novel biocompatible polyurethane (PU) elastomers were carried out using curcumin and 1,4-butanediol (1,4-BDO) via step growth polymerization reaction of hydroxyl terminated polybutadiene (HTPB), toluene diisocyanate (TDI) and chitin to improve the biocompatibility, antibacterial and an...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2019.11.097

    authors: Amjed N,Bhatti IA,Zia KM,Iqbal J,Jamil Y

    更新日期:2020-07-01 00:00:00

  • Structural and morphological evaluation of CNC reinforced PVA/Starch biodegradable films.

    abstract::Nanocomposite films containing cellulose nanocrystals (CNC), as the reinforcing phase, and poly(vinyl alcohol) (PVA)/starch (S) blend, as the matrix, were prepared by solution casting technique. For the preparation, 5, 10, 15 wt% CNC suspension were incorporated in blends containing 90 wt% PVA/10 wt% S, 75 wt% PVA/25 ...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2018.05.036

    authors: Popescu MC,Dogaru BI,Goanta M,Timpu D

    更新日期:2018-09-01 00:00:00

  • Evaluation of nitriloacetic acid modified cellulose film on adsorption of methylene blue.

    abstract::A novel composite film (MCαN) based on microcrystalline cellulose (MCC) and nitrilotriacetic acid anhydride (NTAA) was prepared via casting method for the adsorption of methylene blue (MB) from aqueous solution. FT-IR, XRD, elemental analysis and TGA analysis demonstrated the success of modification. The swelling beha...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2018.03.146

    authors: Shi C,Tao F,Cui Y

    更新日期:2018-07-15 00:00:00

  • Interactions and compatibility of 11 S globulin from Vicia faba seeds and sodium salt of carboxymethylcellulose in an aqueous medium.

    abstract::This work studies specific interactions and compatibility between a legumin and a linear carboxylated polysaccharide using gel permeation chromatography, sedimentation analysis, SDS gel electrophoresis, viscometry and phase analysis measurements. It uses the system water/11 S globulin/CMC as a model. Carboxymethylcell...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2005.12.011

    authors: Antonov YA,Dmitrochenko AP,Leontiev AL

    更新日期:2006-02-28 00:00:00

  • Nanoparticles based on chitosan hydrochloride/hyaluronic acid/PEG containing curcumin: In vitro evaluation and pharmacokinetics in rats.

    abstract::Nanoparticles based on chitosan hydrochloride (CSH)-hyaluronic acid (HA)-PEG were prepared for delivering curcumin (CUR) (CUR-PNPs) to brain tumor. CUR-PNPs of 245.9nm and spherical morphology were obtained at optimized CSH/HA/PEG20000/CUR ratios with negative charge of about -27.2mV and EE of approximately 93.3%. Cyt...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2017.04.105

    authors: Xu Y,Asghar S,Yang L,Chen Z,Li H,Shi W,Li Y,Shi Q,Ping Q,Xiao Y

    更新日期:2017-09-01 00:00:00

  • Chromium (III) coordination capacity of chitosan.

    abstract::Polycationic chitosan has a strong coordination to heavy metal ions due to its multifunctional hydroxyl and amino groups. However, due to the fast and facile dissolution of chitosan in acidic medium, it is difficult to measure the exact adsorption amount or coordination capacity accurately. In this work, a simple meth...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2020.01.203

    authors: Ganglo C,Rui J,Zhu Q,Shan J,Wang Z,Su F,Liu D,Xu J,Guo M,Qian J

    更新日期:2020-04-01 00:00:00

  • Modulating cationicity of chitosan hydrogel to prevent hypertrophic scar formation during wound healing.

    abstract::It is of great clinical significance to design wound dressing materials with combined excellent wound healing properties and superior capability to suppress hypertrophic scar formation. This study aimed to examine if and how the cationicity of chitosan would affect the hypertrophic scar-related outcomes, through prepa...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2020.03.161

    authors: Zhang N,Gao T,Wang Y,Liu J,Zhang J,Yao R,Wu F

    更新日期:2020-07-01 00:00:00

  • Antioxidant, antibacterial and antitumoural activities of kraft lignin from hardwood fractionated by acid precipitation.

    abstract::Kraft lignin, so far useful for energy generation, has been gathering considerable attention as an alternative material to replace fossil-based resources mainly due to its high phenolic content. However, the wide molecular weight distribution and chemical composition heterogeneity led to the development of fractionati...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2020.11.033

    authors: Lourençon TV,de Lima GG,Ribeiro CSP,Hansel FA,Maciel GM,da Silva K,Winnischofer SMB,de Muniz GIB,Magalhães WLE

    更新日期:2021-01-01 00:00:00

  • Vaccinomics strategy to concoct a promising subunit vaccine for visceral leishmaniasis targeting sandfly and leishmania antigens.

    abstract::Visceral leishmaniasis (VL) has been declared as one of the most severely neglected tropical diseases by the World Health Organization report 2017. Cumulative incidences of treatment failure and drug resistance, demanding a potential treatment and preventive strategy for VL. In this study, we have devised a multi-epit...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2020.04.097

    authors: Ojha R,Pandey RK,Prajapati VK

    更新日期:2020-08-01 00:00:00

  • Osmolyte induced enhancement of expression and solubility of human dihydrofolate reductase: An in vivo study.

    abstract::The process of recombinant protein production in E. coli system is often hampered by the formation of insoluble aggregates. Human Dihydrofolate reductase (hDHFR), an enzyme involved in the synthesis of purine, thymidilate and several other amino acids like glycine, methionine and serine is highly aggregation prone. It...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2017.05.143

    authors: Rashid N,Thapliyal C,Chaudhuri Chattopadhyay P

    更新日期:2017-10-01 00:00:00

  • Tantalizing role of p53 molecular pathways and its coherent medications in neurodegenerative diseases.

    abstract::Neurodegenerative diseases are incongruous, commonly age-related disorders characterized by progressive neuronal loss, comprising the most prevalent being Alzheimer's disease, Parkinson's disease, and Huntington's disease. Perilous health states are anticipated following the neurodegeneration. Their etiology remains l...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章,评审

    doi:10.1016/j.ijbiomac.2021.01.042

    authors: Talebi M,Talebi M,Kakouri E,Farkhondeh T,Pourbagher-Shahri AM,Tarantilis PA,Samarghandian S

    更新日期:2021-01-10 00:00:00

  • The role of Cys271 in conformational changes of arginine kinase.

    abstract::Arginine kinase (AK), a crucial enzyme in energy metabolism, buffers cellular ATP levels by catalyzing the reversible phosphoryl transfer between ATP and arginine. To better understand the role of Cys271 in conformational changes of AK from greasyback shrimp (Metapenaeus ensis), we replaced the residue with serine and...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2011.04.002

    authors: Liu N,Wang JS,Wang WD,Pan JC

    更新日期:2011-07-01 00:00:00

  • Role of reducing terminals in unfractionated and low-molecular-mass heparins in causing free radical generation and loss of structure and activity of trypsin.

    abstract::The role of both the length of saccharide chain and reducing terminals in the heparin molecule in causing oxidative effects on proteins was investigated by employing unfractionated and low-molecular-mass heparins (LMMH), with both intact and reduced reducing terminals on bovine trypsin. The effects of heparin were fou...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/s0141-8130(99)00072-0

    authors: Finotti P,Pagetta A,Corvaja C

    更新日期:1999-11-01 00:00:00

  • Conformation of bovine submaxillary mucin layers on hydrophobic surface as studied by biomolecular probes.

    abstract::In the present study, the conformational changes of bovine submaxillary mucin (BSM) adsorbed on a hydrophobic surface (polystyrene (PS)) as a function of concentration in bulk solution (up to 2mg/mL) have been investigated with biomolecular probe-based approaches, including bicinchoninic acid (BCA), enzyme-linked immu...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2014.09.035

    authors: Pakkanen KI,Madsen JB,Lee S

    更新日期:2015-01-01 00:00:00

  • Preparation and rheological characterization of Chitosan-Gelatine@ZnO-Si nanoparticles.

    abstract::Chitosan (Chi) and gelatine (Gel) polymer blends with ZnO nanoparticles loaded on silica were synthesized through a simple solution method under ultrasonic irradiation at different concentration ratios (5:3, 1:3 and 3:5). The viscosity characteristics of the nanostructure were investigated by using ultrasound irradiat...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2019.06.231

    authors: Karakuş S

    更新日期:2019-09-15 00:00:00

  • Green synthesis of biopolymer-silver nanoparticle nanocomposite: an optical sensor for ammonia detection.

    abstract::Biopolymer used for the production of nanoparticles (NPs) has attracted increasing attention. In the presence article we use aqueous solution of polysaccharide Cyamopsis tetragonaloba commonly known as guar gum (GG), from plants. GG acts as reductive preparation of silver nanoparticles which are found to be <10 nm in ...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2012.06.033

    authors: Pandey S,Goswami GK,Nanda KK

    更新日期:2012-11-01 00:00:00

  • Structural characterization of lignin in heartwood, sapwood, and bark of eucalyptus.

    abstract::Understanding the distribution and structural features of lignin in heartwood, sapwood, and bark of terrestrial plants is important to optimize the industrial utilization of lignocellulose. In this work, the lignins in heartwood, sapwood, and bark of Eucalyptus urophylla × E. grandis were comparatively studied. Confoc...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2019.07.137

    authors: Xiao MZ,Chen WJ,Hong S,Pang B,Cao XF,Wang YY,Yuan TQ,Sun RC

    更新日期:2019-10-01 00:00:00

  • Use of guar gum, gum arabic, pectin, beta-glucan and inulin for microencapsulation of anthocyanins from chokeberry.

    abstract::The aim of this study was to use micro-encapsulation technology to create microcapsules containing anthocyanins from chokeberry with guar gum, gum arabic, pectin, β-glucan and inulin as wall material. Aqueous extracts from chokeberry fruit were enclosed and spray dried using maltodextrin as a coating material with the...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2019.02.073

    authors: Pieczykolan E,Kurek MA

    更新日期:2019-05-15 00:00:00

  • C-terminal modification of monoclonal antibody drugs: amidated species as a general product-related substance.

    abstract::Twelve therapeutic mAbs, comprising 10 IgG1s and 2 IgG4s, were analyzed by a peptide mapping technique to detect and quantify C-terminal modifications. C-terminal amidated structures were found in 8 out of the 12 mAbs. An in vitro study using a commercially available peptidylglycine alpha-amidating monooxygenase (PAM)...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2012.09.016

    authors: Tsubaki M,Terashima I,Kamata K,Koga A

    更新日期:2013-01-01 00:00:00

  • Diagnosing human blood clotting deficiency.

    abstract::There are different clotting factors present in blood, carries the clotting cascade and excessive bleeding may cause a deficiency in the clotting Diagnosis of this deficiency in clotting drastically reduces the potential fatality. For enabling a sensor to detect the clotting factors, suitable probes such as antibody a...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章,评审

    doi:10.1016/j.ijbiomac.2018.05.084

    authors: Ong CC,Gopinath SCB,Rebecca LWX,Perumal V,Lakshmipriya T,Saheed MSM

    更新日期:2018-09-01 00:00:00