Abstract:
:Wound dressing is a very important factor in the process of wound healing as proper wound care can accelerate the recovery of the wound. In this study, zein nanofibrous mats with fiber diameters around 350-500 nm were prepared by electrospinning and silver (Ag) nanoparticles around 20 nm were concurrently synthesized in situ into the mats. The electrospun nanofibers were characterized by Field Emission-Scanning Electron Microscopy (FE-SEM), Transmission Electron Microscopy (TEM), Fourier Transform Infrared Spectroscopy (FTIR) and X-ray photoelectron spectroscopy (XPS) analysis. Cell viability and activity of fibroblasts cells in zein/Ag mats were also evaluated and results demonstrated good cytocompatibility and attachment of cells on the composite nanofibers. Also, the bactericidal activity of the fabricated mats against gram-positive Staphylococcus aureus (S. aureus) and gram-negative Escherichia coli (E. coli) was investigated via zone of inhibition test and results showed high anti-bacterial performance.
journal_name
Int J Biol Macromoljournal_title
International journal of biological macromoleculesauthors
Dashdorj U,Reyes MK,Unnithan AR,Tiwari AP,Tumurbaatar B,Park CH,Kim CSdoi
10.1016/j.ijbiomac.2015.06.026subject
Has Abstractpub_date
2015-09-01 00:00:00pages
1-7eissn
0141-8130issn
1879-0003pii
S0141-8130(15)00429-8journal_volume
80pub_type
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