Abstract：
BACKGROUND:Previous studies have examined associations between alcohol use in pregnancy and offspring birth size but evidence on whether associations persist during childhood is limited. METHODS:We examined the association between maternal drinking during pregnancy and trajectories of offspring weight and height from 0 to 10 years in 7597 mother-child pairs in the Avon Longitudinal Study of Parents and Children. To strengthen the inference, we compared the maternal alcohol-offspring growth association with the partner alcohol-offspring growth association, to partially control for unmeasured confounding. We also performed sensitivity analyses restricting our analysis to women of white ethnicity and participants with three or more growth measures. RESULTS:Maternal occasional or light daily drinking during pregnancy was not associated with reduced birth weight, birth length or offspring growth trajectories up to age 10 years. The infants of heavy drinking mothers were born 0.78cm shorter (95% CI -1.34, -0.22) and 0.22kg lighter (95% CI -0.34, -0.09) than infants of pregnancy abstainers but by age 10, offspring of heavy drinking mothers were of comparable height (mean difference 0.59cm, 95% CI -0.93, 2.11) and weight (mean difference 0.41kg, 95% CI -0.70, 1.52). These associations were not observed for heavy partner drinking and were not altered in sensitivity analyses. CONCLUSION:Maternal occasional or light daily drinking is not associated with birth weight, birth length or postnatal growth, but residual confounding may persist. Maternal heavy drinking may have an intrauterine association with reduced birth weight and length but this association is overcome during childhood.
journal_name
Drug Alcohol Dependjournal_title
Drug and alcohol dependenceauthors
O'Keeffe LM,Kearney PM,Greene RA,Zuccolo L,Tilling K,Lawlor DA,Howe LDdoi
10.1016/j.drugalcdep.2015.02.035subject
Has Abstractpub_date
2015-08-01 00:00:00pages
323-9eissn
0376-8716issn
1879-0046pii
S0376-8716(15)00138-6journal_volume
153pub_type
杂志文章abstract：:Cathinone, the principal alkaloid of Khat, was compared to the psychomotor stimulant d-amphetamine on a number of neurochemical measures. Like d-amphetamine, d,l-cathinone released and blocked the uptake of tritiated dopamine (DA) in synaptosomal preparations. In addition, repeated high doses of d,l-cathinone produced...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/0376-8716(82)90067-9
更新日期：1982-08-01 00:00:00
abstract：BACKGROUND:Drug addiction researchers have begun to study dopamine partial agonists as potential therapeutic agents. The partial dopamine D(2) receptor agonist aripiprazole has recently been tested as a treatment for stimulant and alcohol dependence in both animal and clinical studies. METHODS:A randomized and placebo...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.drugalcdep.2008.10.024
更新日期：2009-04-01 00:00:00
abstract：AIM:To assess whether substance-abusing people have a higher risk of dying from unintentional acute intoxication in specific periods of the year. METHODS:A total of 15,792 deaths (males=14,259; females=1533) were ascertained to be due to unintentional acute intoxication by illicit drugs in Italy in the study period (1...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/s0376-8716(03)00186-8
更新日期：2003-10-24 00:00:00
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journal_title：Drug and alcohol dependence
pub_type： 杂志文章,评审
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更新日期：2017-09-01 00:00:00
abstract：AIMS:The primary aim of the present study is to determine the one year periodic prevalence of dispension of different analgesics to patients in long term opioid maintenance therapy (OMT). The secondary aim is to determine to which extent non-opioid analgesics are used as first line analgesics. DESIGN:The study is a ph...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2010.12.014
更新日期：2011-07-01 00:00:00
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journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2020.108391
更新日期：2021-01-01 00:00:00
abstract：:We investigated the associations of self-reported HIV status and risky injection practices with dependent variables measuring readiness and motivation for treatment and depression among 550 clients at two residential drug abuse treatment programs. The results suggest that a positive HIV status may be associated with m...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/0376-8716(94)90133-3
更新日期：1994-01-01 00:00:00
abstract：BACKGROUND:Binge drinking (BD) consists of heavy episodic alcohol use. Whereas the World Health Organization (WHO) defines BD as 60g of alcohol or more per occasion, the National Institute on Alcoholism and Alcohol Abuse (NIAAA) conceives BD as drinking 70g (men) or 56g (women) in less than two hours. We compared the s...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章,多中心研究
doi：10.1016/j.drugalcdep.2017.01.034
更新日期：2017-06-01 00:00:00
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journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/0376-8716(96)01238-0
更新日期：1996-06-01 00:00:00
abstract：OBJECTIVE:Flavored e-cigarette use has risen rapidly, especially among young adults who also smoke cigarettes. We sought to determine whether flavoring enhances the subjective rewarding value, relative reinforcing value, and absolute reinforcing value of an e-cigarette with nicotine compared to an unflavored e-cigarett...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2016.06.030
更新日期：2016-09-01 00:00:00
abstract：BACKGROUND:The aim of the study was to investigate the prevalence of injecting drug use and associated risk behaviour among a sentinel sample of ecstasy users. METHODS:Cross-sectional surveys were conducted with regular ecstasy users as part of an annual monitoring study of ecstasy and related drug markets in all Aust...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2005.11.014
更新日期：2006-07-27 00:00:00
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journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/0376-8716(79)90013-9
更新日期：1979-05-01 00:00:00
abstract：INTRODUCTION:There is concern that recreational marijuana legalization (RML) may lead to increased cannabis use disorder (CUD) among youth due to increased marijuana use. This study investigates whether adolescent substance use disorder treatment admissions for marijuana use increased in Colorado and Washington followi...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2020.107960
更新日期：2020-05-01 00:00:00
abstract：:This study examines the problem of effective treatment for alcoholic patients with concurrent psychopathology. The subjects were 131 male veterans admitted to the Coatesville Veterans Administration Medical Center. They remained in an alcohol rehabilitation program at least five days following detoxification and were ...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/0376-8716(81)90083-1
更新日期：1981-08-01 00:00:00
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journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2012.12.016
更新日期：2013-07-01 00:00:00
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journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2007.02.017
更新日期：2007-10-08 00:00:00
abstract：AIMS:To present the prevalence and correlates of hallucinogen use disorders (HUDs: abuse or dependence) and subthreshold dependence. METHODS:The study sample included adolescents aged 12-17 years (N=55,286) who participated in the National Survey on Drug Use and Health (2004-2006). Data were collected with a combinati...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2009.04.014
更新日期：2009-09-01 00:00:00
abstract：:Male rats were given ethanol via an intragastric catheter (8.0-11.0 g/kg per day) for either 8 weeks daily or for four 2-week periods with a 2-week period of no drug treatment intervening between each period of ethanol administration (binge). Older rats were administered ethanol for 2 weeks, to assess the effects of a...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/0376-8716(89)90014-8
更新日期：1989-04-01 00:00:00
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journal_title：Drug and alcohol dependence
pub_type： 临床试验,杂志文章
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更新日期：2000-02-01 00:00:00
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journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2016.01.005
更新日期：2016-03-01 00:00:00
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journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2019.107648
更新日期：2019-12-01 00:00:00
abstract：:Using a national population sample of adults who had ever consumed at least 12 drinks per year, men and women were compared in terms of the proportions who had stopped drinking because of alcohol problems. Overall, 24% of the male drinkers and 31% of the female drinkers had stopped drinking as of the time of interview...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/0376-8716(94)90010-8
更新日期：1994-08-01 00:00:00
abstract：:Although family, twin, and adoption studies indicate that genes play a significant etiologic role in the development of substance use disorders (SUDs), detecting specific genes has been difficult due to uncertainties about how to define SUDs, genetic heterogeneity and variable phenotypic expression of SUD genotypes. W...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2007.07.002
更新日期：2008-01-01 00:00:00
abstract：BACKGROUND:Contingency management (CM) is efficacious for reducing drug use, but it has rarely been applied to patients with severe and persistent mental health problems. This study evaluated the efficacy of CM for reducing cocaine use in psychiatric patients treated at a community mental health center. METHODS:Ninete...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.drugalcdep.2012.10.017
更新日期：2013-06-01 00:00:00
abstract：:The role of Delta(9)-tetrahydrocannabinol (THC) in driver impairment and motor vehicle crashes has traditionally been established in experimental and epidemiological studies. Experimental studies have repeatedly shown that THC impairs cognition, psychomotor function and actual driving performance in a dose related man...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章,评审
doi：10.1016/j.drugalcdep.2003.10.008
更新日期：2004-02-07 00:00:00
abstract：BACKGROUND:Because methamphetamine (METH) pharmacokinetics after single iv doses show significant differences between male and female rats, we hypothesized that pharmacokinetic differences in METH disposition could be a contributing factor to the patterns of METH self-administration behaviors in rats. METHODS:For the ...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2015.02.032
更新日期：2015-05-01 00:00:00
abstract：:Naltrexone was approved by the US Food and Drug Administration (FDA) in December 1994. Although it is one of only two medications for alcohol rehabilitation approved in the US, naltrexone is not frequently prescribed. This paper examines the factors limiting physicians' use of naltrexone. Data were collected through a...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/s0376-8716(03)00134-0
更新日期：2003-09-10 00:00:00
abstract：BACKGROUND:Ethanol and cocaine are widely abused drugs triggering long-lasting changes in neuronal circuits and synaptic transmission through the regulation of enzyme activity and gene expression. Compelling evidence indicates that the ubiquitin-proteasome system plays a role in the molecular changes induced by addicti...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2016.02.012
更新日期：2016-04-01 00:00:00
abstract：:This paper provides a detailed analysis of the 2-year outcomes for 351 drug misusers allocated on an intention-to-treat basis to methadone maintenance or methadone reduction treatments. Both groups showed substantial reductions in their use of illicit drugs and in other outcome areas. However, whereas most methadone m...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/s0376-8716(00)00211-8
更新日期：2001-05-01 00:00:00
abstract：BACKGROUND:Disruptions in motor control are often overlooked features of chronic cocaine users. During a simple sensorimotor integration task, for example, cocaine users activate a larger area of cortex than controls but have lower functional connectivity between the cortex and dorsal striatum, which is further correla...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2015.07.1196
更新日期：2015-12-01 00:00:00
