Abstract:
:This paper provides a detailed analysis of the 2-year outcomes for 351 drug misusers allocated on an intention-to-treat basis to methadone maintenance or methadone reduction treatments. Both groups showed substantial reductions in their use of illicit drugs and in other outcome areas. However, whereas most methadone maintenance patients received maintenance, only about one third of those allocated to methadone reduction received methadone reduction, and many actually received a form of methadone maintenance. Reduction patients were more likely to receive low doses of methadone, and were less likely to remain in treatment. For maintenance patients, higher doses and retention in treatment were both associated with improvements in illicit heroin use at 2 years. For the reduction patients, the more rapidly the methadone was reduced, the worse the heroin use outcomes. For patients in both treatment conditions, reductions in heroin use were associated with improvements in other outcome areas. The more severely dependent patients showed better outcomes in methadone maintenance. Methadone reduction treatment processes were associated with poor outcomes, and many patients who were allocated to methadone reduction treatment did not receive reduction treatment as intended. This calls into question the appropriateness of either the initial treatment planning process or the treatment delivery process, or both. A clearer distinction should be made between methadone maintenance and methadone reduction. Treatment goals should be made explicit both to the patient and to the clinical staff at the start of treatment. We suggest the need for a reappraisal of the goals and procedures of methadone reduction treatment.
journal_name
Drug Alcohol Dependjournal_title
Drug and alcohol dependenceauthors
Gossop M,Marsden J,Stewart D,Treacy Sdoi
10.1016/s0376-8716(00)00211-8keywords:
subject
Has Abstractpub_date
2001-05-01 00:00:00pages
255-64issue
3eissn
0376-8716issn
1879-0046pii
S0376-8716(00)00211-8journal_volume
62pub_type
杂志文章abstract:BACKGROUND:Healthcare professionals are crucial in the identification and accessibility to treatment for people with substance use disorders. Our objective was to assess health professionals' attitudes towards patients with substance use disorders and examine the consequences of these attitudes on healthcare delivery f...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章,评审
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更新日期:2013-07-01 00:00:00
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journal_title:Drug and alcohol dependence
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journal_title:Drug and alcohol dependence
pub_type: 杂志文章,随机对照试验
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journal_title:Drug and alcohol dependence
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journal_title:Drug and alcohol dependence
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2000-07-01 00:00:00
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journal_title:Drug and alcohol dependence
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journal_title:Drug and alcohol dependence
pub_type: 杂志文章
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journal_title:Drug and alcohol dependence
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更新日期:1987-11-30 00:00:00
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journal_title:Drug and alcohol dependence
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journal_title:Drug and alcohol dependence
pub_type: 杂志文章,评审
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更新日期:2017-10-01 00:00:00
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journal_title:Drug and alcohol dependence
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journal_title:Drug and alcohol dependence
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.drugalcdep.2014.03.030
更新日期:2014-07-01 00:00:00
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journal_title:Drug and alcohol dependence
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journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2011.09.013
更新日期:2012-04-01 00:00:00
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journal_title:Drug and alcohol dependence
pub_type: 杂志文章
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journal_title:Drug and alcohol dependence
pub_type: 杂志文章
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journal_title:Drug and alcohol dependence
pub_type: 杂志文章
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更新日期:2015-10-01 00:00:00
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journal_title:Drug and alcohol dependence
pub_type: 杂志文章
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更新日期:1998-11-01 00:00:00
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journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2012.09.012
更新日期:2013-04-01 00:00:00
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journal_title:Drug and alcohol dependence
pub_type: 杂志文章
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更新日期:2016-05-01 00:00:00
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journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2006.01.002
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journal_title:Drug and alcohol dependence
pub_type: 杂志文章,随机对照试验
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更新日期:2013-09-01 00:00:00
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journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2014.08.011
更新日期:2014-11-01 00:00:00
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journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2012.04.024
更新日期:2012-11-01 00:00:00
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journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2013.05.018
更新日期:2013-11-01 00:00:00
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journal_title:Drug and alcohol dependence
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1995-10-01 00:00:00