Improving the anti-ovarian cancer activity of docetaxel with biodegradable self-assembly micelles through various evaluations.

abstract：:Cell detachment by laminar shear stresses was used to characterize cellular interactions with hydrophilic glass and hydrophobic silane. In this study, we examined whether smaller, rounder cells were preferentially detached by laminar flow, and whether cell detachment occurred by dissociation of adhesion proteins and t...

journal_title：Biomaterials

authors： Truskey GA,Proulx TL

更新日期：1993-01-01 00:00:00

abstract：:The development of biocompatible photopolymerizing polymers for biomedical and tissue engineering applications has the potential to reduce the invasiveness and cost of biomaterial implants designed to repair or augment tissues. However, more information is needed about the cellular toxicity of the compounds and initia...

journal_title：Biomaterials

authors： Williams CG,Malik AN,Kim TK,Manson PN,Elisseeff JH

更新日期：2005-04-01 00:00:00

abstract：:Current advances in stem cell biology have brought much hope for therapy of neuro-degenerative diseases. However, neural stem cells (NSCs) are rare adult stem cells, and the use of non-NSCs requires efficient and high-yielding lineage-specific differentiation prior to transplantation for efficacy. We report on the eff...

journal_title：Biomaterials

authors： Wang CH,Wu CC,Hsu SH,Liou JY,Li YW,Wu KK,Lai YK,Yen BL

更新日期：2013-04-01 00:00:00

abstract：:Mesenchymal condensation is a pre-requisite of chondrogenesis during embryonic development. The current understanding of chondrogenesis is limited in terms of chondrogenic condensation mechanisms. In particular, the role of matrix stiffness on homotypic cell-cell interactions leading to the establishment of distinct a...

journal_title：Biomaterials

authors： Ghosh S,Laha M,Mondal S,Sengupta S,Kaplan DL

更新日期：2009-11-01 00:00:00

abstract：:Previously we demonstrated the ability of ethyl glycinato substituted polyphosphazenes to neutralize the acidic degradation products and control the degradation rate of poly(lactic acid-glycolic acid) (PLAGA) by blending. In this study, blends of high strength poly[(50% ethyl alanato) (50% p-phenyl phenoxy) phosphazen...

journal_title：Biomaterials

authors： Deng M,Nair LS,Nukavarapu SP,Kumbar SG,Jiang T,Krogman NR,Singh A,Allcock HR,Laurencin CT

更新日期：2008-01-01 00:00:00

abstract：:Although an expanded polytetrafluoroethylene patch is a suitable synthetic material to repair large abdominal wall defects, lack of tissue ingrowth into the patch may give rise to herniation at the fascia-patch interface. This study was undertaken to determine whether perforations and/or ethanol pretreatment improved ...

journal_title：Biomaterials

authors： Simmermacher RK,van der Lei B,Schakenraad JM,Bleichrodt RP

更新日期：1991-01-01 00:00:00

abstract：:The aim of this study was to evaluate the bacterial adherence to biodegradable self-reinforced polyglycolic acid (SR-PGA) and self-reinforced poly-DL-lactic acid (SR-PLA 96) spiral stents in vitro. They are used as temporary urethral stents in urology. Gold-plated metal wire, polyurethane and latex were used as contro...

journal_title：Biomaterials

authors： Pétas A,Vuopio-Varkila J,Siitonen A,Välimaa T,Talja M,Taari K

更新日期：1998-04-01 00:00:00

abstract：:For a temporomandibular joint prosthesis, an estimation of the wear rate was needed, prior to patient application. Therefore, we determined the in vitro wear rate of the ball-socket articulation of this prosthesis, consisting of a metal head and an ultra-high molecular weight polyethylene (UHMWPE) cup. The basic testi...

journal_title：Biomaterials

authors： Van Loon JP,Verkerke GJ,de Bont LG,Liem RS

更新日期：1999-08-01 00:00:00

abstract：:Sintered bovine cancellous bone exhibited excellent biocompatiblity, high porosity and have an interconnecting porous structure allowing for bone ingrowth. However, the main mineral constitution of sintered bovine bone-hydroxyapatite (Ca10(PO4)6(OH)2, HAP) seems to be too stable in vivo. For improving its bioactivity,...

journal_title：Biomaterials

authors： Lin FH,Liao CJ,Chen KS,Sun JS

更新日期：1999-03-01 00:00:00

abstract：:Nanomaterials with integrated multiple imaging and therapeutic modalities possess great potentials in accurate cancer diagnostics and enhanced therapeutic efficacy. Traditional strategies for achieving multimodality nanoplatform through one by one combination of different modalities are challenged by the complicated s...

journal_title：Biomaterials

authors： He X,Peng C,Qiang S,Xiong LH,Zhao Z,Wang Z,Kwok RTK,Lam JWY,Ma N,Tang BZ

更新日期：2020-04-01 00:00:00

abstract：:Multilayered coatings composed of mixtures of HA and P2O5-based bioactive glasses are of potential clinical benefit in orthopaedic and dental surgery. Pre-immersion of these materials has been reported to further enhance their efficacy in vivo, although the precise biological effects of this treatment are not yet know...

journal_title：Biomaterials

authors： Ferraz MP,Knowles JC,Olsen I,Monteiro FJ,Santos JD

更新日期：2000-04-01 00:00:00

abstract：:Titanium and its alloys are widely used in load-bearing implants as a result of their excellent mechanical properties and corrosion resistance. In order to improve their performances with respect to osseointegration, the use of bioactive coatings has been suggested. Polypyrrole (PPy) has been chosen as coating polymer...

journal_title：Biomaterials

authors： De Giglio E,Guascito MR,Sabbatin L,Zambonin G

更新日期：2001-10-01 00:00:00

abstract：:Both efficiency and safety profiles are crucial for promotion of gene delivery systems towards practical applications. A promising template system was previously developed based on block catiomer of poly(ethylene glycol) (PEG)-b-poly{N'-[N-(2-aminoethyl)-2-aminoehtyl]aspartamide}-cholesteryl [PEG-PAsp(DET)-cholesteryl...

journal_title：Biomaterials

authors： Chen Q,Osada K,Ge Z,Uchida S,Tockary TA,Dirisala A,Matsui A,Toh K,Takeda KM,Liu X,Nomoto T,Ishii T,Oba M,Matsumoto Y,Kataoka K

更新日期：2017-01-01 00:00:00

abstract：:A surface graft polymer with one or two phosphorylcholine (PC) polarheads at the terminus of the growing chain end was prepared by sequential reactions on a glass substrate. The dithiocarbamate group covalently bound to glass surfaces was derivatized with one or two PC groups and then irradiated with ultraviolet light...

journal_title：Biomaterials

authors： Matsuda T,Kaneko M,Ge S

更新日期：2003-11-01 00:00:00

abstract：:Amorphous carbon films have attracted much attention recently due to their good biocompatibility. Diamond-like carbon (DLC), one form of amorphous carbon that is widely used in many kinds of industries, has been proposed for use in blood contacting medical devices. However, the blood coagulation mechanism on DLC in a ...

journal_title：Biomaterials

authors： Yang P,Huang N,Leng YX,Chen JY,Fu RK,Kwok SC,Leng Y,Chu PK

更新日期：2003-08-01 00:00:00

abstract：:The pore architecture in 3-D polymeric scaffoldings plays a critical role in tissue engineering as it provides the framework for the seeded cells to organize into a functioning tissue. In the present paper, we investigate the effect of freezing regime on the pore microstructure in 3-D alginate scaffolds, fabricated by...

journal_title：Biomaterials

authors： Zmora S,Glicklis R,Cohen S

更新日期：2002-10-01 00:00:00

abstract：:Thermosensitive hydrogels based on poly(γ-ethyl-L-glutamate)-poly(ethylene glycol)-poly(γ-ethyl-L-glutamate) triblock copolymers (PELG-PEG-PELG) were prepared for localized and sustained delivery of anticancer drugs. The polypeptide-based hydrogels showed much lower critical gelation concentration than the traditional...

journal_title：Biomaterials

authors： Cheng Y,He C,Ding J,Xiao C,Zhuang X,Chen X

更新日期：2013-12-01 00:00:00

abstract：:We have developed a method to modify cross-linked hyaluronic acid with peptides containing the Arg-Gly-Asp sequence. The material created by this process is a three-dimensional porous matrix capable of supporting integrin receptor-mediated cell attachment. Peptide density can be controlled by varying the reaction cond...

journal_title：Biomaterials

authors： Glass JR,Dickerson KT,Stecker K,Polarek JW

更新日期：1996-06-01 00:00:00

abstract：:Envelope, capsid and nucleic acids are key viral components that are all involved in crucial events during virus infection. Thus simultaneous labeling of these key components is an indispensable prerequisite for monitoring comprehensive virus infection process and dissecting virus infection mechanism. Baculovirus was ...

journal_title：Biomaterials

authors： Wen L,Lin Y,Zhang ZL,Lu W,Lv C,Chen ZL,Wang HZ,Pang DW

更新日期：2016-08-01 00:00:00

abstract：:Platelet-derived growth factor BB (PDGF-BB) was an important inductive factor during wound healing, but the lack of efficient delivery system limited its clinical application. Here, a peptide of seven amino acids was firstly utilized to engineer PDGF-BB to construct a collagen-targeting system. This peptide functioned...

journal_title：Biomaterials

authors： Lin H,Chen B,Sun W,Zhao W,Zhao Y,Dai J

更新日期：2006-11-01 00:00:00

abstract：:The generation of effective tissue engineered bone grafts requires efficient exchange of nutrients and mechanical stimulus. Bioreactors provide a manner in which this can be achieved. We have recently developed a biaxial rotating bioreactor with efficient fluidics through in-silico modeling. Here we investigated its p...

journal_title：Biomaterials

authors： Zhang ZY,Teoh SH,Chong WS,Foo TT,Chng YC,Choolani M,Chan J

更新日期：2009-05-01 00:00:00

abstract：:In order to increase the functionality of islets encapsulated in a biohybrid artificial pancreas (BAP), it was proposed that co-encapsulation with insulinotropic agents would improve insulin secretion from islets. To prevent agents from leaking out, conjugation with high-molecular-weight polymers was inevitable. In th...

journal_title：Biomaterials

authors： Kim S,Wan Kim S,Bae YH

更新日期：2005-06-01 00:00:00

abstract：:Various compositions of Na2OCaO-P2O5 glasses are prepared to estimate glass formation, dissolution properties and cytotoxicity. In the wide composition range of 40 mol% of P2O5 or more, clear glass samples were obtained. The estimated glass forming region was consistent with other ternary phosphate glass systems. The ...

journal_title：Biomaterials

authors： Uo M,Mizuno M,Kuboki Y,Makishima A,Watari F

更新日期：1998-12-01 00:00:00

abstract：:Polyethylene terephthalate (PET), ethylene-vinyl alcohol copolymer (EVOH) and Nylon 6 in plate form were treated with silane-coupling agents, a titanium alkoxide-alcohol solution and a hot HCl solution to form a thin crystalline titanium oxide layer. When placed in a simulated body fluid with ion concentrations nearly...

journal_title：Biomaterials

authors： Balas F,Kawashita M,Nakamura T,Kokubo T

更新日期：2006-03-01 00:00:00

abstract：:Co-polymeric hydrogels of collagen and poly(hydroxyethyl methacrylate) (pHEMA) were prepared using an ammonium persulphate-sodium metabisulphite redox initiation technique. Fluorescein isothiocyanate (FITC)-labelled bovine serum albumin (BSA) was entrapped into these hydrogels. These gels were modified differently by ...

journal_title：Biomaterials

authors： Rao JK,Ramesh DV,Rao KP

更新日期：1994-04-01 00:00:00

abstract：:The surface of soft contact lenses made of crosslinked poly(2-hydroxyethyl methacrylate). pHEMA, has been investigated with atomic force microscopy in contact mode. The friction force and adhesive force measurements were able to differentiate the non-crosslinked pHEMA chains from the surface of the crosslinked pHEMA n...

journal_title：Biomaterials

authors： Kim SH,Marmo C,Somorjai GA

更新日期：2001-12-01 00:00:00

abstract：:This study was undertaken to evaluate the role of collagen matrix to enhance platelet-rich plasma (PRP) effects on pro-inflammatory cytokine-induced arthritic model. We have previously demonstrated the highly regenerative roles of PRP to restore disc degeneration and osteoporosis. In this study, PRP modulated by colla...

journal_title：Biomaterials

authors： Wu CC,Chen WH,Zao B,Lai PL,Lin TC,Lo HY,Shieh YH,Wu CH,Deng WP

更新日期：2011-09-01 00:00:00

abstract：:Development of non-invasive assay for the accurate diagnosis of progressive liver diseases (e.g., fatty liver and hepatocellular carcinoma (HCC)) is of great clinical significance and remains to be a big challenge. Herein, we reported the synthesis of strawberry-like Fe3O4-Au hybrid nanoparticles at room temperature t...

journal_title：Biomaterials

authors： Zhao HY,Liu S,He J,Pan CC,Li H,Zhou ZY,Ding Y,Huo D,Hu Y

更新日期：2015-05-01 00:00:00

abstract：:Calcium phosphates (CaP) and phosphate-based glass (P-glass, xCaO-(0.55-x) Na(2)O-0.45P(2)O(5) composition) composite coatings were obtained on a strong ZrO(2) to improve biocompatibility, the mechanical strength and biological activity. Hydroxyapatite (HA) and P-glass mixed powder slurries were coated on the ZrO(2) s...

journal_title：Biomaterials

authors： Kim HW,Georgiou G,Knowles JC,Koh YH,Kim HE

更新日期：2004-08-01 00:00:00

abstract：:Elemental metal nanoparticles like cadmium and silver are known to cause oxidative stress and are also highly toxic. Yet for gold nanoparticles (AuNPs), it is not well established whether these particles are biologically toxic. Here we show that AuNPs, which were taken up by MRC-5 human lung fibroblasts in vitro, indu...

journal_title：Biomaterials

authors： Li JJ,Hartono D,Ong CN,Bay BH,Yung LY

更新日期：2010-08-01 00:00:00