Characterization of two different antibody specificities recognizing distinct antigenic determinants in free lipid A of Escherichia coli.

abstract：:The adhesion of K21a, K26, K36, and K50 capsulated Klebsiella strains to ileocecal (HCT-8) and bladder (T24) epithelial cell lines was significantly lower than that of their corresponding spontaneous noncapsulated variants K21a/3, K26/1, K36/3, and K50/3, respectively. Internalization of the bacteria by both epithelia...

journal_title：Infection and immunity

authors： Sahly H,Podschun R,Oelschlaeger TA,Greiwe M,Parolis H,Hasty D,Kekow J,Ullmann U,Ofek I,Sela S

更新日期：2000-12-01 00:00:00

abstract：:A virus, 78-238, isolated from the cerebrospinal fluid of a dog with neurological dysfunction, was characterized as a paramyxovirus. This conclusion was supported by viral cytopathic effects and morphological appearance of virions and nucleocapsids in infected cells. Nucleocapsids were found in the cytoplasm of all in...

journal_title：Infection and immunity

authors： Baumgärtner WK,Metzler AE,Krakowka S,Koestner A

更新日期：1981-03-01 00:00:00

abstract：:Tuberculosis is one of the most important infectious diseases worldwide. The susceptibility to this disease depends to a great extent on the innate immune response against mycobacteria. Host defense peptides (HDP) are one of the first barriers to counteract infection. Cathelicidin (LL-37) is an HDP that has many immun...

journal_title：Infection and immunity

authors： Torres-Juarez F,Cardenas-Vargas A,Montoya-Rosales A,González-Curiel I,Garcia-Hernandez MH,Enciso-Moreno JA,Hancock RE,Rivas-Santiago B

更新日期：2015-12-01 00:00:00

abstract：:Murine cytomegalovirus pools from various in vitro and in vivo sources were compared for virulence in suckling mice in an effort to identify the conditions which were necessary for the production of virulent and attenuated viruses. Virus passaged in tracheal ring and salivary gland organ cultures, where virus is produ...

journal_title：Infection and immunity

authors： Selgrade MK,Nedrud JG,Collier AM,Gardner DE

更新日期：1981-09-01 00:00:00

abstract：:Human sera were examined by an enzyme-linked immunosorbent assay for immunoglobulin G (IgG) and IgM antibodies to purified type III polysaccharide of group B streptococci. The antigen-binding capacity of a reference human serum was determined by a radioimmunoassay, and the total antibody content was determined by quan...

journal_title：Infection and immunity

authors： Anthony BF,Concepcion NF,Wass CA,Heiner DC

更新日期：1984-10-01 00:00:00

abstract：:The Th-2 response to microfilariae of Brugia malayi in BALB/c mice is associated with peritoneal eosinophilia. These eosinophils had an activated hypodense phenotype in vivo and expressed high levels of the class II major histocompatibility complex (MHC). Interleukin 4 up-regulated the class II MHC, whereas gamma inte...

journal_title：Infection and immunity

authors： Mawhorter SD,Pearlman E,Kazura JW,Boom WH

更新日期：1993-12-01 00:00:00

abstract：:Exoenzyme S (ExoS), an ADP-ribosylating enzyme produced by the opportunistic pathogen Pseudomonas aeruginosa, is directly translocated into eukaryotic cells by bacterial contact. Within the cell, ExoS ADP-ribosylates the cell signaling protein Ras and causes inhibition of DNA synthesis and alterations in cytoskeletal ...

journal_title：Infection and immunity

authors： Olson JC,Fraylick JE,McGuffie EM,Dolan KM,Yahr TL,Frank DW,Vincent TS

更新日期：1999-06-01 00:00:00

abstract：:Porphyromonas gingivalis is a gram-negative anaerobic bacterium that is considered the key etiologic agent of chronic periodontitis. Arg- and Lys-gingipain cysteine proteinases produced by P. gingivalis are key virulence factors and are believed to be essential for significant tissue component degradation, leading to ...

journal_title：Infection and immunity

authors： Andrian E,Grenier D,Rouabhia M

更新日期：2004-08-01 00:00:00

abstract：:The goal of this study was to determine the roles of eosinophils and neutrophils in innate and adaptive protective immunity to larval Strongyloides stercoralis in mice. The experimental approach used was to treat mice with an anti-CCR3 monoclonal antibody to eliminate eosinophils or to use CXCR2-/- mice, which have a ...

journal_title：Infection and immunity

authors： Galioto AM,Hess JA,Nolan TJ,Schad GA,Lee JJ,Abraham D

更新日期：2006-10-01 00:00:00

abstract：:The parameters of a persistent-state measles virus infection in BGM/MV cells were examined. The BGM/MV cell line was established by cocultivation of measles virus-infected primary C3H mouse brain cells with a stable line of African green monkey kidney cells (BGM). Initially, a morphologically mixed population of cells...

journal_title：Infection and immunity

authors： Menna JH,Collins AR,Flanagan TD

更新日期：1975-01-01 00:00:00

abstract：:We used inhibitors of receptor-mediated endocytosis to study the mechanisms of infectivity, especially the uptake mechanism, of Chlamydia trachomatis for cultured cells. The effect of methylamine and monodansylcadaverine on the different stages of the chlamydial growth cycle in McCoy cells was examined. There was a do...

journal_title：Infection and immunity

authors： Söderlund G,Kihlström E

更新日期：1983-05-01 00:00:00

abstract：:Cholera is an acute diarrheal disease that is caused by the gram-negative bacterium Vibrio cholerae. The low efficacy of currently available killed-whole-cell vaccines and the reactinogenicity coupled with potential reversion of live vaccines have thus far precluded widespread vaccination for the control of cholera. R...

journal_title：Infection and immunity

authors： Wu JY,Wade WF,Taylor RK

更新日期：2001-12-01 00:00:00

abstract：:The development of chronic pathology in mice at 2 to 10 months after inoculation of 10(2) T. cruzi trypomastigotes can be prevented by preimmunization with live, attenuated culture parasites (strain TCC). Swiss mice received one or three immunizing inoculations of 10(6) TCC organisms and were challenged with 10(2) Tul...

journal_title：Infection and immunity

authors： Basombrío MA,Besuschio S

更新日期：1982-04-01 00:00:00

abstract：:The effects of passive administration of neutralizing monoclonal antibodies (MAB) to respiratory syncytial virus glycoproteins (GP90 and VP70) was evaluated in cotton rats challenged with respiratory syncytial virus. Animals injected with MAB to VP70 had lower mean viral titers in lung tissues than did controls (log10...

journal_title：Infection and immunity

authors： Walsh EE,Schlesinger JJ,Brandriss MW

更新日期：1984-02-01 00:00:00

abstract：:Most strains of Shigella flexneri 2a and enteroaggregative Escherichia coli carry a highly conserved chromosomal locus which encodes a 109-kDa secreted mucinase (called Pic) and, on the opposite strand in overlapping fashion, an oligomeric enterotoxin called ShET1, encoded by the setA and setB genes. Here, we characte...

journal_title：Infection and immunity

authors： Behrens M,Sheikh J,Nataro JP

更新日期：2002-06-01 00:00:00

abstract：:Streptococcus pneumoniae is a major cause of pneumonia and meningitis. Airway colonization is a necessary precursor to disease, but little is known about how the bacteria establish and maintain colonization. Carbohydrates are required as a carbon source for pneumococcal growth and, therefore, for colonization. Free ca...

journal_title：Infection and immunity

authors： Marion C,Burnaugh AM,Woodiga SA,King SJ

更新日期：2011-03-01 00:00:00

abstract：:Tumor necrosis factor alpha (TNF) is thought to play a major role in the pathogenesis of septic shock. Anti-TNF antibody was preadministered in low-dose endotoxin lethality models in which BALB/c mice were challenged with small amounts of lipopolysaccharide following their sensitization with either carrageenan (CAR) o...

journal_title：Infection and immunity

authors： Franks AK,Kujawa KI,Yaffe LJ

更新日期：1991-08-01 00:00:00

abstract：:Cysteine proteases, including Arg-gingipain of Porphyromonas gingivalis, have been implicated as important virulence factors in periodontal diseases. These enzymes are also involved in the hemagglutinating activity of the organisms. In order to determine the role of proteases in the colonization of the gingival margin...

journal_title：Infection and immunity

authors： Tokuda M,Duncan M,Cho MI,Kuramitsu HK

更新日期：1996-10-01 00:00:00

abstract：:The action of trehalose-6, 6'-dimycolate (cord factor) of Mycobacterium tuberculosis to induce site II-specific inhibition of mitochondrial oxidative phosphorylation and to stimulate adenosine triphosphatase activity was neutralized by its specific antibody. The activity was restored after dissociation of cord factor ...

journal_title：Infection and immunity

authors： Kato M

更新日期：1974-07-01 00:00:00

abstract：:Polyinosinate-polycytidylate [poly(I).poly(C)]-induced interferon production in cultures of human foreskin fibroblast strains was increased by ultraviolet irradiation of cells at the time of exposure to inducer or at 2 h after induction. Incubation of cells with interferon prior to induction (priming) and ultraviolet ...

journal_title：Infection and immunity

authors： Mozes LW,Havell EA,Gradoville ML,Vilcek J

更新日期：1974-11-01 00:00:00

abstract：:C-reactive protein (CRP) has long been known to appear in the sera of individuals with inflammatory processes, but its role in host defense against bacterial infection is unclear. We have recently demonstrated that CRP in the presence of the classical complement pathway markedly enhances the opsonization of Streptococ...

journal_title：Infection and immunity

authors： Mold C,Edwards KM,Gewurz H

更新日期：1982-09-01 00:00:00

abstract：:Bordetella parapertussis, a respiratory tract pathogen commonly regarded as noninvasive, was found to invade HeLa 229 cell monolayers. Following treatment of the monolayers with gentamicin, numbers of viable B. parapertussis recovered were comparable to those of invasive Salmonella and Shigella isolates. Invasion occu...

journal_title：Infection and immunity

authors： Ewanowich CA,Sherburne RK,Man SF,Peppler MS

更新日期：1989-04-01 00:00:00

abstract：:Cryptococcus neoformans NIH 409 was cultured in a defined medium containing D-[1-13C]xylose (Xyl), D-[1-13C]mannose (Man), or D-[1-13C]mannitol as the sole carbon source. The distribution of 13C in the Man, Xyl, glucuronic acid (GlcA), and O-acetyl constituents of native and de-O-acetylated glucuronoxylomannan (GXM) w...

journal_title：Infection and immunity

authors： Cherniak R,O'Neill EB,Sheng S

更新日期：1998-06-01 00:00:00

abstract：:Interleukin-10 (IL-10)-producing B cells (B10 cells) play a critical role in the immune system balance by negatively regulating inflammatory responses. This study was conducted to determine the effect of local B10 cell induction on periodontal inflammation and bone loss in ligature-induced experimental periodontitis i...

journal_title：Infection and immunity

authors： Yu P,Hu Y,Liu Z,Kawai T,Taubman MA,Li W,Han X

更新日期：2016-12-29 00:00:00

abstract：:Peptidoglycan from a Staphylococcus epidermidis strain, isolated from a patient with septicemia, was preincubated with human serum. This mixture was then investigated for its potency to induce tumor necrosis factor (TNF) secretion by human blood monocytes. TNF was measured in the supernatants by using a bioassay and/o...

journal_title：Infection and immunity

authors： Mattsson E,Rollof J,Verhoef J,Van Dijk H,Fleer A

更新日期：1994-09-01 00:00:00

abstract：:The ability of various strains of rats to produce interferon in response to polyriboinosinic-polyribocytodilic acid was investigated. ACI and DA (RT-1a), BN (RT-1n), Buffalo (RT-1b), August (RT-1c), and GH (RT-1l) strains produced low levels of interferon in response to intraperitoneal administration of polyriboinosin...

journal_title：Infection and immunity

authors： Davis CT,Blankenhorn EP,Murasko DM

更新日期：1984-02-01 00:00:00

abstract：:The antigens of Haemophilus somnus recognized by convalescent bovine serum were studied by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and Western blotting with a protein A-peroxidase conjugate. The same two 76K and 40K antigens were predominant in whole-bacterium preparations and in outer-membrane-enric...

journal_title：Infection and immunity

authors： Corbeil LB,Arthur JE,Widders PR,Smith JW,Barbet AF

更新日期：1987-06-01 00:00:00

abstract：:During bacterial infection of the bovine mammary gland, large numbers of leukocytes migrate into the udder, resulting in the establishment of a host response against the pathogen. Currently, the specific leukocyte populations mediating this immune response are not well defined. In the studies described here, we analyz...

journal_title：Infection and immunity

authors： Soltys J,Quinn MT

更新日期：1999-12-01 00:00:00

abstract：:Brucella abortus is a facultative intracellular bacterial pathogen that causes abortion in domestic animals and undulant fever in humans. The mechanism of virulence of Brucella spp. is not fully understood yet. Furthermore, genes that allow Brucella to reach the intracellular niche and to interact with host cells need...

journal_title：Infection and immunity

authors： Rosinha GM,Freitas DA,Miyoshi A,Azevedo V,Campos E,Cravero SL,Rossetti O,Splitter G,Oliveira SC

更新日期：2002-09-01 00:00:00

abstract：:Engerotoxins isolated from Vibrio cholerae and toxigenic Escherichia coli cause permeability alterations in rabbit skin. Firm induration and erythema are observed within 18 to 24 h, and visualization of the reaction may be enhanced by intravenous injection of Pontamine sky blue dye. Two skin permeability factors (PF) ...

journal_title：Infection and immunity

authors： Sandefur PD,Peterson JW

更新日期：1976-09-01 00:00:00