Ferromagnetism induced by entangled charge and orbital orderings in ferroelectric titanate perovskites.

abstract：:High-aspect ratio nanostructures such as nanowires and nanotubes are a powerful new tool for accessing the cell interior for delivery and sensing. Controlling and optimizing cellular access is a critical challenge for this new technology, yet even the most basic aspect of this process, whether these structures directl...

journal_title：Nature communications

authors： Xu AM,Aalipour A,Leal-Ortiz S,Mekhdjian AH,Xie X,Dunn AR,Garner CC,Melosh NA

更新日期：2014-04-07 00:00:00

abstract：:The liver parenchyma is composed of hepatocytes and bile duct epithelial cells (BECs). Controversy exists regarding the cellular origin of human liver parenchymal tissue generation during embryonic development, homeostasis or repair. Here we report the existence of a hepatobiliary hybrid progenitor (HHyP) population i...

journal_title：Nature communications

authors： Segal JM,Kent D,Wesche DJ,Ng SS,Serra M,Oulès B,Kar G,Emerton G,Blackford SJI,Darmanis S,Miquel R,Luong TV,Yamamoto R,Bonham A,Jassem W,Heaton N,Vigilante A,King A,Sancho R,Teichmann S,Quake SR,Nakauchi H,Rash

更新日期：2019-07-26 00:00:00

abstract：:The emergence of antibiotic resistant bacteria is a major threat to the practice of modern medicine. Photobactericidal agents have obtained significant attention as promising candidates to kill bacteria, and they have been extensively studied. However, to obtain photobactericidal activity, an intense white light sourc...

journal_title：Nature communications

authors： Hwang GB,Huang H,Wu G,Shin J,Kafizas A,Karu K,Toit HD,Alotaibi AM,Mohammad-Hadi L,Allan E,MacRobert AJ,Gavriilidis A,Parkin IP

更新日期：2020-03-05 00:00:00

abstract：:The ultrafast dynamics of hot carriers in graphene are key to both understanding of fundamental carrier-carrier interactions and carrier-phonon relaxation processes in two-dimensional materials, and understanding of the physics underlying novel high-speed electronic and optoelectronic devices. Many recent experiments ...

journal_title：Nature communications

authors： Mihnev MT,Kadi F,Divin CJ,Winzer T,Lee S,Liu CH,Zhong Z,Berger C,de Heer WA,Malic E,Knorr A,Norris TB

更新日期：2016-05-25 00:00:00

abstract：:The caudal-related homeobox transcription factor CDX2 is expressed in leukemic cells but not during normal blood formation. Retroviral overexpression of Cdx2 induces AML in mice, however the developmental stage at which CDX2 exerts its effect is unknown. We developed a conditionally inducible Cdx2 mouse model to deter...

journal_title：Nature communications

authors： Vu T,Straube J,Porter AH,Bywater M,Song A,Ling V,Cooper L,Pali G,Bruedigam C,Jacquelin S,Green J,Magor G,Perkins A,Chalk AM,Walkley CR,Heidel FH,Mukhopadhyay P,Cloonan N,Gröschel S,Mallm JP,Fröhling S,Scholl C,

更新日期：2020-06-15 00:00:00

abstract：:The principles governing the recruitment of interneurons during acceleration in vertebrate locomotion are unknown. In the mouse, the V2a spinal interneurons are dispensable for left-right coordination at low locomotor frequencies, but their function is essential for maintaining left-right coordination at high frequenc...

journal_title：Nature communications

authors： Zhong G,Sharma K,Harris-Warrick RM

更新日期：2011-01-01 00:00:00

abstract：:Microalbuminuria is an important clinical marker of several cardiovascular, metabolic, and other diseases such as diabetes, hypertension, atherosclerosis, and cancer. The accurate detection of microalbuminuria relies on albumin quantification in the urine, usually via an immunoturbidity assay; however, like many antib...

journal_title：Nature communications

authors： Budhathoki-Uprety J,Shah J,Korsen JA,Wayne AE,Galassi TV,Cohen JR,Harvey JD,Jena PV,Ramanathan LV,Jaimes EA,Heller DA

更新日期：2019-08-09 00:00:00

abstract：:Drought comprehensively affects different interlinked aspects of the terrestrial water cycle, which have so far been mostly investigated without direct comparison. Resolving the partitioning of water deficit during drought into blue-water runoff and green-water evapotranspiration fluxes is critical, as anomalies in th...

journal_title：Nature communications

authors： Orth R,Destouni G

更新日期：2018-09-06 00:00:00

abstract：:Perisomatic inhibition of pyramidal neurons is established by fast-spiking, parvalbumin-expressing interneurons (PV cells). Failure to assemble adequate perisomatic inhibition is thought to underlie the aetiology of neurological dysfunction in seizures, autism spectrum disorders and schizophrenia. Here we show that in...

journal_title：Nature communications

authors： Baohan A,Ikrar T,Tring E,Xu X,Trachtenberg JT

更新日期：2016-09-09 00:00:00

abstract：:The current trends of crop yield improvements are not expected to meet the projected rise in demand. Genomic selection uses molecular markers and machine learning to identify superior genotypes with improved traits, such as growth. Plant growth directly depends on rates of metabolic reactions which transform nutrients...

journal_title：Nature communications

authors： Tong H,Küken A,Nikoloski Z

更新日期：2020-05-15 00:00:00

abstract：:There is enormous interest in engineering topological photonic systems. Despite intense activity, most works on topological photonic states (and more generally bosonic states) amount in the end to replicating a well-known fermionic single-particle Hamiltonian. Here we show how the squeezing of light can lead to the fo...

journal_title：Nature communications

authors： Peano V,Houde M,Brendel C,Marquardt F,Clerk AA

更新日期：2016-03-02 00:00:00

abstract：:Base editors (BEs) are RNA-guided CRISPR-Cas-derived genome editing tools that induce single-nucleotide changes. The limitations of current BEs lie in their low precision (especially when multiple target nucleotides of the deaminase are present within the activity window) and their restriction to targets that are in p...

journal_title：Nature communications

authors： Tan J,Zhang F,Karcher D,Bock R

更新日期：2020-01-31 00:00:00

abstract：:Biocatalytic cyclization is highly desirable for efficient synthesis of biologically derived chemical substances, such as the commodity chemicals ε-caprolactam and δ-valerolactam. To identify biocatalysts in lactam biosynthesis, we develop a caprolactam-detecting genetic enzyme screening system (CL-GESS). The Alcalige...

journal_title：Nature communications

authors： Yeom SJ,Kim M,Kwon KK,Fu Y,Rha E,Park SH,Lee H,Kim H,Lee DH,Kim DM,Lee SG

更新日期：2018-11-29 00:00:00

abstract：:The originally published version of this Article contained an error in the spelling of the author Md. Saiful Islam, which was incorrectly given as Saiful Islam. This has now been corrected in both the PDF and HTML versions of the Article. ...

journal_title：Nature communications

authors： Wilkins SE,Islam MS,Gannon JM,Markolovic S,Hopkinson RJ,Ge W,Schofield CJ,Chowdhury R

更新日期：2018-04-23 00:00:00

abstract：:The cytosolic antibody receptor TRIM21 possesses unique ubiquitination activity that drives broad-spectrum anti-pathogen targeting and underpins the protein depletion technology Trim-Away. This activity is dependent on formation of self-anchored, K63-linked ubiquitin chains by the heterodimeric E2 enzyme Ube2N/Ube2V2....

journal_title：Nature communications

authors： Kiss L,Zeng J,Dickson CF,Mallery DL,Yang JC,McLaughlin SH,Boland A,Neuhaus D,James LC

更新日期：2019-10-03 00:00:00

abstract：:Metal-organic frameworks (MOFs) are well known for their tunable structure and porosity. Many studies have shown they are promising for various important applications, for which their performance can be further enhanced by encapsulating functional species, such as luminescent guest molecules, within the frameworks. Al...

journal_title：Nature communications

authors： Sun CY,Wang XL,Zhang X,Qin C,Li P,Su ZM,Zhu DX,Shan GG,Shao KZ,Wu H,Li J

更新日期：2013-01-01 00:00:00

abstract：:Positive selection in the thymus provides low-affinity T-cell receptor (TCR) engagement to support the development of potentially useful self-major histocompatibility complex class I (MHC-I)-restricted T cells. Optimal positive selection of CD8(+) T cells requires cortical thymic epithelial cells that express β5t-cont...

journal_title：Nature communications

authors： Sasaki K,Takada K,Ohte Y,Kondo H,Sorimachi H,Tanaka K,Takahama Y,Murata S

更新日期：2015-06-23 00:00:00

abstract：:Exocytic transmitter release is regulated by the SNARE complex, which contains a vesicular protein, synaptobrevin2 (Sb2). However, Sb2 vesicular arrangement is unclear. Here we use super-resolution fluorescence microscopy to study the prevalence and distribution of endogenous and exogenous Sb2 in single vesicles of as...

journal_title：Nature communications

authors： Singh P,Jorgačevski J,Kreft M,Grubišić V,Stout RF Jr,Potokar M,Parpura V,Zorec R

更新日期：2014-05-07 00:00:00

abstract：:Extracellular vesicles have an important function in cellular communication. Here, we show that human and mouse monocytes release TGF-β1-transporting vesicles in response to the pathogenic fungus Candida albicans. Soluble β-glucan from C. albicans binds to complement receptor 3 (CR3, also known as CD11b/CD18) on monoc...

journal_title：Nature communications

authors： Halder LD,Jo EAH,Hasan MZ,Ferreira-Gomes M,Krüger T,Westermann M,Palme DI,Rambach G,Beyersdorf N,Speth C,Jacobsen ID,Kniemeyer O,Jungnickel B,Zipfel PF,Skerka C

更新日期：2020-05-11 00:00:00

abstract：:Tyrosine sulfation, a well-characterized post-translation modification in eukaryotes, has not previously been reported in prokaryotes. Here, we demonstrate that the RaxST protein from the Gram-negative bacterium, Xanthomonas oryzae pv. oryzae, is a tyrosine sulfotransferase. We used a newly developed sulfotransferase ...

journal_title：Nature communications

authors： Han SW,Lee SW,Bahar O,Schwessinger B,Robinson MR,Shaw JB,Madsen JA,Brodbelt JS,Ronald PC

更新日期：2012-01-01 00:00:00

abstract：:Domain walls can be driven by current at very high speeds in nanowires formed from ultra-thin, perpendicularly magnetized cobalt layers and cobalt/nickel multilayers deposited on platinum underlayers due to a chiral spin torque. An important feature of this torque is a magnetic chiral exchange field that each domain w...

journal_title：Nature communications

authors： Ryu KS,Yang SH,Thomas L,Parkin SS

更新日期：2014-05-23 00:00:00

abstract：:Human type 1 insulin-like growth factor receptor is a homodimeric receptor tyrosine kinase that signals into pathways directing normal cellular growth, differentiation and proliferation, with aberrant signalling implicated in cancer. Insulin-like growth factor binding is understood to relax conformational restraints w...

journal_title：Nature communications

authors： Xu Y,Kong GK,Menting JG,Margetts MB,Delaine CA,Jenkin LM,Kiselyov VV,De Meyts P,Forbes BE,Lawrence MC

更新日期：2018-02-26 00:00:00

abstract：:To balance immunity and tolerance, the endogenous pool of Foxp3+ regulatory T (Treg) cells is tightly controlled, but the underlying mechanisms of this control remain poorly understood. Here we show that the number of Treg cells is negatively regulated by the kinase Lkb1 in dendritic cells (DCs). Conditional knockout ...

journal_title：Nature communications

authors： Chen S,Fang L,Guo W,Zhou Y,Yu G,Li W,Dong K,Liu J,Luo Y,Wang B,Li Z,Zhao C,Sun Z,Shen Y,Leng Q,Zhou D,Han Z,Huang H,Ren H,Xu G,Feng X

更新日期：2018-12-13 00:00:00

abstract：:Muscle injury triggers inflammation in which infiltrating mononuclear phagocytes are crucial for tissue regeneration. The interaction of the CCL2/CCR2 and CX3CL1/CX3CR1 chemokine axis that guides phagocyte infiltration is incompletely understood. Here, we show that CX3CR1 deficiency promotes muscle repair and rescues ...

journal_title：Nature communications

authors： Arnold L,Perrin H,de Chanville CB,Saclier M,Hermand P,Poupel L,Guyon E,Licata F,Carpentier W,Vilar J,Mounier R,Chazaud B,Benhabiles N,Boissonnas A,Combadiere B,Combadiere C

更新日期：2015-12-03 00:00:00

abstract：:Untethered small actuators have various applications in multiple fields. However, existing small-scale actuators are very limited in their intractability with their surroundings, respond to only a single type of stimulus and are unable to achieve programmable structural changes under different stimuli. Here, we presen...

journal_title：Nature communications

authors： Dong Y,Wang J,Guo X,Yang S,Ozen MO,Chen P,Liu X,Du W,Xiao F,Demirci U,Liu BF

更新日期：2019-09-09 00:00:00

abstract：:Synapse degeneration is an early and invariant feature of neurodegenerative diseases. Indeed, synapse loss occurs prior to neuronal degeneration and correlates with the symptom severity of these diseases. However, the molecular mechanisms that trigger synaptic loss remain poorly understood. Here we demonstrate that de...

journal_title：Nature communications

authors： Galli S,Lopes DM,Ammari R,Kopra J,Millar SE,Gibb A,Salinas PC

更新日期：2014-10-16 00:00:00

abstract：:Protein tyrosine phosphatases regulate a myriad of essential subcellular signaling events, yet they remain difficult to study in their native biophysical context. Here we develop a minimally disruptive optical approach to control protein tyrosine phosphatase 1B (PTP1B)-an important regulator of receptor tyrosine kinas...

journal_title：Nature communications

authors： Hongdusit A,Zwart PH,Sankaran B,Fox JM

更新日期：2020-02-07 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature communications

authors： Lee CH,Kang TH,Godon O,Watanabe M,Delidakis G,Gillis CM,Sterlin D,Hardy D,Cogné M,Macdonald LE,Murphy AJ,Tu N,Lee J,McDaniel JR,Makowski E,Tessier PM,Meyer AS,Bruhns P,Georgiou G

更新日期：2019-11-26 00:00:00

abstract：:The serotonin transporter (SERT), a member of the neurotransmitter:sodium symporter family, is responsible for termination of serotonergic signaling by re-uptake of serotonin (5-HT) into the presynaptic neuron. Its key role in synaptic transmission makes it a major drug target, e.g. for the treatment of depression, an...

journal_title：Nature communications

authors： Möller IR,Slivacka M,Nielsen AK,Rasmussen SGF,Gether U,Loland CJ,Rand KD

更新日期：2019-04-11 00:00:00

abstract：:The dynamics of many natural and artificial systems are well described as random walks on a network: the stochastic behaviour of molecules, traffic patterns on the internet, fluctuations in stock prices and so on. The vast literature on random walks provides many tools for computing properties such as steady-state pro...

journal_title：Nature communications

authors： Perkins TJ,Foxall E,Glass L,Edwards R

更新日期：2014-10-14 00:00:00