CD4(+), CD25(+), FOXP3 (+) T Regulatory Cell Levels in Obese, Asthmatic, Asthmatic Obese, and Healthy Children.

abstract：:Postoperative ileus is a common complication after intra-abdominal surgery. Nitric oxide produced by macrophages in the inflamed gastrointestinal tract plays a crucial role in the pathogeny of postoperative ileus. Honokiol, extracted from the bark of Magnolia spp., is a natural compound with a biphenolic structure. In...

journal_title：Inflammation

authors： Mihara T,Mikawa S,Kaji N,Endo M,Oikawa T,Tong-Rong J,Ozaki H,Hori M

更新日期：2017-08-01 00:00:00

abstract：:To determine the effect of heat stress on histopathology of acute lung injury (ALI) caused by administration of lipopolysaccharide (LPS), and to determine the roles of tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, interferon (IFN)-gamma, IL-10 and surfactants in heat-induced tolerance to ALI, we administe...

journal_title：Inflammation

authors： Koh Y,Lee YM,Lim CM,Lee SS,Shim TS,Lee SD,Kim WS,Kim DS,Kim WD

更新日期：2001-06-01 00:00:00

abstract：:The newly discovered gamma-PKC-related-protein of human leukocytes (gamma-rp) crossreacts with a polyclonal antibody preparation originally designed to be specific for PKC-gamma (gammaMb-Ab). As this antibody is currently the only suitable probe for gamma-rp, we sought to characterize the binding of the two proteins. ...

journal_title：Inflammation

authors： Smallwood JI,Malawista SE

更新日期：1999-08-01 00:00:00

abstract：:Aberrant activation of the NOD-like receptor (NLR) family, pyrin domain-containing protein 3 (NLRP3) inflammasome, triggers a pathogenic inflammatory response in many inherited neurodegenerative disorders. Inflammation has recently been associated with valosin-containing protein (VCP)-associated diseases, caused by mi...

journal_title：Inflammation

authors： Nalbandian A,Khan AA,Srivastava R,Llewellyn KJ,Tan B,Shukr N,Fazli Y,Kimonis VE,BenMohamed L

更新日期：2017-02-01 00:00:00

abstract：:Alveolar macrophages (AMs) can initiate lung inflammation by producing pro-inflammatory cytokines and chemokines, but they participate actively in the prevention of inflammation during acute lung injury (ALI). Heme oxygenase-1 (HO-1) is mainly expressed in AMs and has anti-inflammatory properties in ALI, but the anti-...

journal_title：Inflammation

authors： Hualin C,Wenli X,Dapeng L,Xijing L,Xiuhua P,Qingfeng P

更新日期：2012-06-01 00:00:00

abstract：:Increased susceptibility of neonates to infection may be related to defects in newborn neutrophil (PMN) functional activities, including altered responses to complement fragments (Cf) and defective microbicidal activity. We therefore compared the kinetics of newborn and adult bovine PMN membrane shape change responses...

journal_title：Inflammation

authors： Holden W,Slauson DO,Zwahlen RD,Suyemoto MM,Doré M,Neilsen NR

更新日期：1989-12-01 00:00:00

abstract：:Mitogen- and stress-activated protein kinase (MSK) is a recently identified nuclear cAMP-regulated enhancer B (CREB) and histone H3 kinase that responds to both mitogen- and stress-activated protein kinases. This study was designed to investigate the protective effect of MSK on the rats with focal ischemia-reperfusion...

journal_title：Inflammation

authors： Zhou Y,Gao G,Li Z,Jiang L

更新日期：2019-12-01 00:00:00

abstract：:Acute lung injury (ALI) is a serious disease with morbidity and mortality in patients. Engeletin (dihydrokaempferol 3-rhamnoside) is a flavanonol glycoside. It can be found in the skin of white grapes and white wine and is widely distributed in southeast Asia. In our study, we evaluated the protective and therapeutic ...

journal_title：Inflammation

authors： Jiang X,Chen L,Zhang Z,Sun Y,Wang X,Wei J

更新日期：2018-08-01 00:00:00

abstract：:Lipopolysaccharide (LPS) is demonstrated to cause "two-hit" injury to liver. Proprotein convertase subtilisin/kexin type 9 (PCSK9) plays an important role in LPS clearance. Hepatocyte nuclear factor-1 alpha (HNF-1α) and sterol regulatory element-binding protein 2 (SREBP2) were reported to be responsible for PCSK9 gene...

journal_title：Inflammation

authors： Zou Y,Li S,Xu B,Guo H,Zhang S,Cai Y

更新日期：2020-02-01 00:00:00

abstract：:Our study is based on the establishment of a cohort of human obese omental adipose tissue and the culture of adipocytes in vitro. To observe the effect of high level of free fatty acid (FFA) on the expression of DNA methyltransferases (DNMTs) and the anti-inflammatory factor Kruppel-like factor 4 (KLF4) in adipocytes ...

journal_title：Inflammation

authors： Deng Y,Qiu T,Zhang M,Wu J,Zhang X,Wang J,Chen K,Feng J,Ha X,Xie J,Wang C,Zhang J

更新日期：2020-06-01 00:00:00

abstract：:Recombinant human tumor necrosis factor-alpha (rTNF) stimulated increased generation of superoxide anion (O2-) by human neutrophils in a concentration-dependent fashion. Preincubation of human neutrophils with rTNF (2.2-2200 units/ml) for 10 min enhanced the subsequent generation of O2- in response to C5a and f-Met-Le...

journal_title：Inflammation

authors： Bajaj MS,Kew RR,Webster RO,Hyers TM

更新日期：1992-06-01 00:00:00

abstract：:Macrophage polarization is a dynamic and integral process of tissue inflammation and remodeling. Here we demonstrate an important role of Aurora kinase A in the regulation of inflammatory M1 macrophage polarization. We found that there was an elevated expression of Aurora-A in M1 macrophages and inhibition of Aurora-A...

journal_title：Inflammation

authors： Ding L,Gu H,Gao X,Xiong S,Zheng B

更新日期：2015-04-01 00:00:00

abstract：:Mastitis is a major disease in humans and other animals and is characterized by mammary gland inflammation. It is a major disease of the dairy industry. Bergenin is an active constituent of the plants of genus Bergenia. Research indicates that bergenin has multiple biological activities, including anti-inflammatory an...

journal_title：Inflammation

authors： Gao XJ,Guo MY,Zhang ZC,Wang TC,Cao YG,Zhang NS

更新日期：2015-01-01 00:00:00

abstract：:Current knowledge implicates pleural mesothelial cells as mainly responsible for inflammatory responses in the pleural space. However, a vast body of recent evidence underscores the important role of fibroblasts in the process of inflammation in several types of tissues. We hypothesize that HPFBs (human pleural fibrob...

journal_title：Inflammation

authors： Loghmani F,Mohammed KA,Nasreen N,Van Horn RD,Hardwick JA,Sanders KL,Antony VB

更新日期：2002-04-01 00:00:00

abstract：:Recent data demonstrated that chemokine CXCL13 mediates neuroinflammation and contributes to the maintenance of neuropathic pain after nerve injury in the spinal cord. Pro-nociceptive chemokines activate mitogen-activated protein kinases (MAPKs) which are potential signaling pathways contributing to the nociceptive be...

journal_title：Inflammation

authors： Zhang Q,Zhu MD,Cao DL,Bai XQ,Gao YJ,Wu XB

更新日期：2017-06-01 00:00:00

abstract：:Chronic prostatitis was the most common type of prostatitis and oxidative stress was reported to be highly elevated in prostatitis patients. In this study, we determined the effect of N-acetylcysteine (NAC) on prostatitis and the molecular mechanism involved in it. Male Sprague-Dawley rats were divided into three grou...

journal_title：Inflammation

authors： Wang LL,Huang YH,Yan CY,Wei XD,Hou JQ,Pu JX,Lv JX

更新日期：2016-04-01 00:00:00

abstract：:This study investigated the expression of miRNA-221 in asthmatics in order to determine whether miRNA-221 plays a role in the development of asthma. Real-time PCR was used to detect the miRNA-221 in both asthmatic and control subjects. In addition, airway inflammation was evaluated by cell counting and tissue biopsy i...

journal_title：Inflammation

authors： Qin HB,Xu B,Mei JJ,Li D,Liu JJ,Zhao DY,Liu F

更新日期：2012-08-01 00:00:00

abstract：:Lipopolysaccharide (LPS) can activate endothelial cells and induce inflammatory injury. Toll-like receptor-4 (TLR-4) is integrally involved in LPS signaling and has a requisite role in the activation of nuclear factor (NF)-κB. A number of studies have demonstrated the cytoprotective action of perfluorocarbon (PFC) bot...

journal_title：Inflammation

authors： Xu S,Wang P,Wei K,Liu F,Liang Z,Zhao X,Li A,Chen L

更新日期：2013-04-01 00:00:00

abstract：:We aimed to compare serum levels of the inflammatory mediators including C-reactive protein (CRP), tumor necrosis factor-α (TNF-α), and asymmetric dimethylarginine (ADMA) in chronic obstructive pulmonary disease (COPD), obstructive sleep apnea syndrome (OSAS), and their coexistence called overlap syndrome (OVS). In ad...

journal_title：Inflammation

authors： Nural S,Günay E,Halici B,Celik S,Ünlü M

更新日期：2013-02-01 00:00:00

abstract：:The ability of peripheral blood neutrophils to injure elements of the alveolar septum was assessed. Experiments consisted of activating previously isolated neutrophils (PMNs) with a soluble (phorbol myristate acetate, PMA) and a particulate (zymosan) trigger, and measuring detachment of 51Cr-labeled epithelial cells. ...

journal_title：Inflammation

authors： Brown DM,Brown GM,Macnee W,Donaldson K

更新日期：1992-02-01 00:00:00

abstract：:Methicillin-resistant Staphylococcus aureus (MRSA) with exogenous cassette DNA containing the methicillin-resistant gene mecA (SCCmec) poses a problem as a drug-resistant bacterium responsible for hospital- and community-acquired infections. The frequency of MRSA detection has recently been increasing rapidly in Japan...

journal_title：Inflammation

authors： Nihonyanagi S,Kanoh Y,Okada K,Uozumi T,Kazuyama Y,Yamaguchi T,Nakazaki N,Sakurai K,Hirata Y,Munekata S,Ohtani S,Takemoto T,Bandoh Y,Akahoshi T

更新日期：2012-06-01 00:00:00

abstract：:Release and activation of pro-inflammatory mediators are among the most important induced factors that are involved in the scorpion envenomation pathogenesis. Inflammatory response and lung reactivity were studied in mice following subcutaneous injection with Androctonus australis hector (Aah) venom. Venom immunodetec...

journal_title：Inflammation

authors： Adi-Bessalem S,Mendil A,Hammoudi-Triki D,Laraba-Djebari F

更新日期：2012-04-01 00:00:00

abstract：:Diabetic retinopathy shares some similarity with chronic inflammation and Müller cells dysfunction may play an important role in its initiation and progression since these cells are thought to be a major source of inflammatory factors. The goal of this study was to examine the effect of cytokines on human retinal Müll...

journal_title：Inflammation

authors： Liu X,Ye F,Xiong H,Hu D,Limb GA,Xie T,Peng L,Yang W,Sun Y,Zhou M,Song E,Zhang DY

更新日期：2014-10-01 00:00:00

abstract：:Chemical alteration of the glucocorticoid, methylprednisolone, has led to the introduction of a new class of compounds called the 21-aminosteroids (21-ASs). The purpose of this study was to investigate the effect of the 21-AS, U74389G, on silica-induced acute lung injury. Male Fischer 344 rats were treated intraperito...

journal_title：Inflammation

authors： Antonini JM,van Dyke K,DiMatteo M,Reasor MJ

更新日期：1995-02-01 00:00:00

abstract：:In the present study, the anti-inflammatory effect of piperine was investigated on monosodium urate crystal-induced inflammation in mice, an experimental model for gouty arthritis, and compared it with that of the nonsteroidal anti-inflammatory drug, indomethacin. The levels of lysosomal enzymes, lipid peroxidation, t...

journal_title：Inflammation

authors： Sabina EP,Nagar S,Rasool M

更新日期：2011-06-01 00:00:00

abstract：:Exacerbations in chronic obstructive pulmonary disease (COPD) reduce quality of life and are associated with a more rapid deterioration of the disease. Growth differentiation factor-15 (GDF-15) is a novel candidate exacerbation biomarker. In this study, we aimed to assess GDF-15 as a biomarker of acute exacerbation of...

journal_title：Inflammation

authors： Mutlu LC,Altintas N,Aydin M,Tulubas F,Oran M,Kucukyalin V,Kaplan G,Gurel A

更新日期：2015-10-01 00:00:00

abstract：:Injury to podocytes leads to proteinuria, a hallmark of most glomerular diseases as well as being associated with the progression of kidney disease. Activation of the Wnt/β-catenin pathway is associated with the pathogenesis of podocyte dysfunction and can play a role in renal injury. Furthermore, the expression of fr...

journal_title：Inflammation

authors： Senouthai S,Wang J,Fu D,You Y

更新日期：2019-08-01 00:00:00

abstract：:The intracellular signaling pathways involved in human monocyte chemotaxis toward a variety of chemoattractant molecules were evaluated using selected pharmacological agents. Neither phosphatidylinositol-3-kinase (P13K) or extracellular signal-regulated kinase (ERK) activity were required for monocyte migration toward...

journal_title：Inflammation

authors： Fine JS,Byrnes HD,Zavodny PJ,Hipkin RW

更新日期：2001-04-01 00:00:00

abstract：:D-limonene epoxidation generates (+)-limonene epoxide, an understudied compound in the pharmacologically point of view. Herein, we investigated the anti-inflammatory and antinociceptive potentialities of (+)-limonene epoxide and suggested a mechanism of action. The anti-inflammatory potential was analyzed using agents...

journal_title：Inflammation

authors： de Almeida AA,Silva RO,Nicolau LA,de Brito TV,de Sousa DP,Barbosa AL,de Freitas RM,Lopes LD,Medeiros JR,Ferreira PM

更新日期：2017-04-01 00:00:00

abstract：:Vascular inflammation plays a key role in the initiation and progression of atherosclerosis, a major complication of diabetes mellitus. Orientin, a C-glycosyl flavonoid, is known to have anxiolytic and antioxidative activity. In this study, we assessed whether orientin can suppress vascular inflammation induced by hig...

journal_title：Inflammation

authors： Ku SK,Kwak S,Bae JS

更新日期：2014-12-01 00:00:00