Expression of asparagine independence in variants of ICR 2A haploid frog cells.

abstract：:Matrix metalloproteinase-2 (MMP-2) is best understood for its biological actions outside the cell. However, MMP-2 also localizes to intracellular compartments and the cytosol where it has several substrates, including troponin I (TnI). Despite a growing list of cytosolic substrates, we currently do not know the mechan...

journal_title：Journal of cellular physiology

authors： Ali MA,Chow AK,Kandasamy AD,Fan X,West LJ,Crawford BD,Simmen T,Schulz R

更新日期：2012-10-01 00:00:00

abstract：:The untransformed stable cell line Met murine hepatocytes (MMH), generated from liver explants of transgenic mice expressing a constitutively active truncated form of the human hepatocyte growth factor receptor (cyto-Met), represents an innovative tool for in vitro studies of liver function. In the present report, we ...

journal_title：Journal of cellular physiology

authors： Bellovino D,Lanyau Y,Garaguso I,Amicone L,Cavallari C,Tripodi M,Gaetani S

更新日期：1999-10-01 00:00:00

abstract：:Epidermal growth factor (EGF) has been shown rapidly to inhibit the transition from G2 phase to mitosis: beyond this transition point the cells are refractory to EGF (Kinzel et al., 1990, Cancer Res., 50:7932-7936). Using synchronized HeLa cells, EGF has now been shown to induce an overall decrease of the histone H1 k...

journal_title：Journal of cellular physiology

authors： Barth H,Kinzel V

更新日期：1995-01-01 00:00:00

abstract：:Osteosarcoma is the most common bone tumor in children and young adults. Although the microRNAs (miRNA) expression analyses of osteosarcoma have been performed previously, the construction of miRNA-messenger RNA (mRNA) networks for osteosarcoma is needed. This study aimed to identify osteosarcoma-related miRNAs throug...

journal_title：Journal of cellular physiology

authors： Ma G,Zhang C,Luo W,Zhao JL,Wang X,Qian Y

更新日期：2019-08-01 00:00:00

abstract：:The next-generation sequencing (NGS) based RNA sequencing (RNA-Seq) and transcriptome profiling offers an opportunity to unveil complex biological processes. Successful RNA-Seq and transcriptome profiling requires a large amount of high-quality RNA. However, NGS-quality RNA isolation is extremely difficult from recalc...

journal_title：Journal of cellular physiology

authors： Sharma D,Golla N,Singh D,Onteru SK

更新日期：2018-03-01 00:00:00

abstract：:Adrenoreceptors (ARs) are widely expressed and play essential roles throughout the body. Different subtype adrenoceptors elicit distinct effects on cell proliferation, but knowledge remains scarce about the subtype-specific effects of β2-ARs on the proliferation of embryonic pluripotent stem (PS) cells that represent ...

journal_title：Journal of cellular physiology

authors： Sun F,Yang XJ,Lv HY,Tang YB,An SM,Ding XP,Li WB,Teng L,Shen Y,Chen HZ,Zhu L

更新日期：2015-11-01 00:00:00

abstract：:The role of hsp27 as an inhibitor of actin polymerization was considered in the context of the actin cytoskeleton and its relationship with focal adhesion formation. The aim of this study was to evaluate the potential effects of hsp27 on focal adhesion formation as a relevant biological consequence of actin stress fib...

journal_title：Journal of cellular physiology

authors： Schneider GB,Hamano H,Cooper LF

更新日期：1998-12-01 00:00:00

abstract：:We have studied the transcriptional activity, steady-state mRNA levels, and steady-state protein levels of the c-myc and transferrin receptor (TfR) genes in murine M1 myeloid leukemia cells arrested in G1 phase of the cell cycle by different methods. When cells are growth-arrested by density inhibition, a technique th...

journal_title：Journal of cellular physiology

authors： Neckers LM,Tsuda H,Weiss E,Pluznik DH

更新日期：1988-05-01 00:00:00

abstract：:Triple-negative breast cancer (TNBC) exhibits a higher level of glycolytic capacity and are commonly associated with an inflammatory microenvironment, but the regulatory mechanism and metabolic crosstalk between the tumor and tumor microenvironment (TME) are largely unresolved. Here, we show that glucose transporter 3...

journal_title：Journal of cellular physiology

authors： Tsai TH,Yang CC,Kou TC,Yang CE,Dai JZ,Chen CL,Lin CW

更新日期：2021-01-09 00:00:00

abstract：:We previously showed that fluid flow, which chondrocytes experience in vivo and which results in a variety of morphological and metabolic changes in cultured articular chondrocytes, can also stimulate a rise in intracellular calcium concentration ([Ca2+]i). However, the mechanism by which Ca2+ is mobilized in response...

journal_title：Journal of cellular physiology

authors： Yellowley CE,Jacobs CR,Donahue HJ

更新日期：1999-09-01 00:00:00

abstract：:Dauricine, a bioactive component of Asiatic Moonseed Rhizome, has been widely used to treat a large number of inflammatory diseases in traditional Chinese medicine. In our study, we demonstrated that dauricine inhibited colon cancer cell proliferation and invasion, and induced apoptosis by suppressing nuclear factor-k...

journal_title：Journal of cellular physiology

authors： Yang Z,Li C,Wang X,Zhai C,Yi Z,Wang L,Liu B,Du B,Wu H,Guo X,Liu M,Li D,Luo J

更新日期：2010-10-01 00:00:00

abstract：:The cell surface phenotype of pluripotent hemopoietic stem cells (CFU-S) and committed progenitors (CFU-C1, CFU-C2, BFU-E) of mouse bone marrow was analyzed with respect to their binding of wheat germ agglutinin (WGA) and two monoclonal antibodies, anti-GM-1.2 and anti-PGP-1. Stained cells were fractionated on the bas...

journal_title：Journal of cellular physiology

authors： Bauman JG,Wagemaker G,Visser JW

更新日期：1986-07-01 00:00:00

abstract：:Osteoblasts are terminally differentiated cells with mesenchymal origins, known to possess pivotal roles in sustaining bone microstructure and homeostasis. These cells are implicated in the pathophysiology of various bone disorders, especially osteoporosis. Over the last few decades, strategies to impede bone resorpti...

journal_title：Journal of cellular physiology

authors： Aslani S,Abhari A,Sakhinia E,Sanajou D,Rajabi H,Rahimzadeh S

更新日期：2019-06-01 00:00:00

abstract：:It was the goal of this study to determine whether during long-term quiescence WI-38 cells gradually lose labile components which then need to be resynthesized before a stimulated cell can progress through G-1 and enter S. The metabolic and molecular status of WI-38 cells was systematically analyzed as they entered an...

journal_title：Journal of cellular physiology

authors： Owen TA,Carter R,Whitman MM,Soprano DR,Soprano KJ

更新日期：1990-01-01 00:00:00

abstract：:Epithelial-mesenchymal transition (EMT), via activation of Wnt signaling, is prevailing in embryogenesis, but postnatally it only occurs in pathological processes, such as in tissue fibrosis and tumor metastasis. Our prior studies led us to speculate that EMT might be involved in the loss of limbal epithelial stem cel...

journal_title：Journal of cellular physiology

authors： Kawakita T,Espana EM,Higa K,Kato N,Li W,Tseng SC

更新日期：2013-01-01 00:00:00

abstract：:MUC4 is a heterodimeric membrane mucin, composed of a mucin subunit ASGP-1 (MUC4alpha) and a transmembrane subunit ASGP-2 (MUC4beta), which has been implicated in the protection of epithelial cell surfaces. Surprisingly, development and characterization of a new monoclonal antibody (mAb), called 1G8, against ASGP-2 de...

journal_title：Journal of cellular physiology

authors： Zhang J,Perez A,Yasin M,Soto P,Rong M,Theodoropoulos G,Carothers Carraway CA,Carraway KL

更新日期：2005-07-01 00:00:00

abstract：:Vascular endothelial cells (EC), communicating with one another across gap junctions, are usually made dysfunctional by hypoxia and reoxygenation (H/R); however, very limited information exists regarding the effects of H/R on the endothelial gap junctions. We investigated whether H/R interferes with endothelial gap ju...

journal_title：Journal of cellular physiology

authors： Zhang YW,Morita I,Nishida M,Murota SI

更新日期：1999-09-01 00:00:00

abstract：:Long suspected, recently recognized, and increasingly studied, non protein-coding RNAs (ncRNAs) are emerging as key drivers of biological control and pathology. Since their discovery in 1993, microRNAs (miRNAs) have been the subject of intense research focus and investigations have revealed striking findings, establis...

journal_title：Journal of cellular physiology

authors： Tye CE,Gordon JA,Martin-Buley LA,Stein JL,Lian JB,Stein GS

更新日期：2015-03-01 00:00:00

abstract：:The secosteroid hormone 1alpha, 25-dihydroxyvitamin D3 (1,25D) has been shown to regulate the growth and differentiation of human prostate cancer (PCa) cells, although the precise molecular mechanisms mediating these effects have not been defined. Previous studies in our laboratory demonstrated that the antiproliferat...

journal_title：Journal of cellular physiology

authors： Lambert JR,Kelly JA,Shim M,Huffer WE,Nordeen SK,Baek SJ,Eling TE,Lucia MS

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:MiR-152 has been reported as a tumor suppressor microRNA that is downregulated in a number of cancers, including colorectal cancer (CRC). A recent study suggested that miR-152 could be one of the key regulators of CRC. The aim of this study is to investigate the role of miR-152 in CRC and its mechanisms. ME...

journal_title：Journal of cellular physiology

authors： Ghazanchaei A,Mansoori B,Mohammadi A,Biglari A,Baradaran B

更新日期：2018-01-01 00:00:00

abstract：:Two transport systems for neutral amino acids have been characterised in LLC-PK, cells. The first, which transports alanine in a sodium-dependent manner, also mediates alanine exchange and is perferentially inhibited by serine, cysteine, and alpha-amino-n-butyric acid. This system resembles the ASC system in Ehrlich a...

journal_title：Journal of cellular physiology

authors： Sepúlveda FV,Pearson JD

更新日期：1982-08-01 00:00:00

abstract：:Activation of hepatic progenitor cells (HPCs) is commonly observed in chronic liver disease and Wnt/β-catenin signaling plays a crucial role in the expansion of HPCs. However, the molecular mechanisms that regulate the activation of Wnt/β-catenin signaling in the liver, especially in HPCs, remain largely elusive. Here...

journal_title：Journal of cellular physiology

authors： Ding ZY,Liang HF,Jin GN,Chen WX,Wang W,Datta PK,Zhang MZ,Zhang B,Chen XP

更新日期：2014-05-01 00:00:00

abstract：:Raloxifene (RAL), a selective estrogen receptor (ER) modulator (SERM) seems to induce apoptosis in both androgen-dependent and -independent prostate cell (PC) lines via activation of ERβ and an antagonistic effect on ERα. In this study, we evaluated the effects of RAL on epithelial PC growth using the two following in...

journal_title：Journal of cellular physiology

authors： Rossi V,Bellastella G,De Rosa C,Abbondanza C,Visconti D,Maione L,Chieffi P,Della Ragione F,Prezioso D,De Bellis A,Bellastella A,Sinisi AA

更新日期：2011-05-01 00:00:00

abstract：:Regulation of lipid synthesis from acetate in human diploid fibroblast cultures has been studied at various passage levels and at different stages of cell growth. When cultures were transferred to lipid free medium, a stimulation of [14C]acetate incorporation into lipid occurred within three to six hours after removal...

journal_title：Journal of cellular physiology

authors： Howard BV,Howard WJ,Kefalides NA

更新日期：1976-10-01 00:00:00

abstract：:Lesional psoriatic epidermis displays a number of phenotypic changes that are distinct from the differentiation program found in normal interfollicular epidermis. In psoriatic epidermis, keratinocytes are hyperproliferative and several differentiation-associated molecules are expressed that are absent in normal skin (...

journal_title：Journal of cellular physiology

authors： Van Ruissen F,de Jongh GJ,Zeeuwen PL,Van Erp PE,Madsen P,Schalkwijk J

更新日期：1996-08-01 00:00:00

abstract：:Wg/Wnts are paracrine and autocrine ligands that activate distinct signaling pathways while being internalized through surface receptors. Converging and contrasting views are shaping our understanding of whether, where, and how endocytosis may modulate Wnt signaling. We gather considerable amount of evidences to elabo...

journal_title：Journal of cellular physiology

authors： Feng Q,Gao N

更新日期：2015-06-01 00:00:00

abstract：:The tuftelin protein isoforms undergo post-translation modifications, and are ubiquitously expressed in various tissues in embryos, adults, and tumors. Developmental and pathological studies suggested an apparent correlation between oxygen deprivation and tuftelin expression. The aim of the study was therefore to inve...

journal_title：Journal of cellular physiology

authors： Leiser Y,Silverstein N,Blumenfeld A,Shilo D,Haze A,Rosenfeld E,Shay B,Tabakman R,Lecht S,Lazarovici P,Deutsch D

更新日期：2011-01-01 00:00:00

abstract：:Peripheral nerve physiology and regeneration has been observed and investigated in literature but surgical applications to reconstruct and restore motor or sensory functions are still in a developmental phase. The peripheral nerve progresses slowly and incompletely compared with other tissues, it may provoke separatio...

journal_title：Journal of cellular physiology

authors： Riccio M,Marchesini A,Pugliese P,De Francesco F

更新日期：2019-04-01 00:00:00

abstract：:Previously we showed a rapid and transient inhibition of gap junctional communication (GJC) by platelet-derived growth factor (PDGF) in T51B rat liver epithelial cells expressing wild-type platelet-derived growth factor beta receptors (PDGFrbeta). This action of PDGF correlated with the hyperphosphorylation of the gap...

journal_title：Journal of cellular physiology

authors： Hossain MZ,Ao P,Boynton AL

更新日期：1998-08-01 00:00:00

abstract：:The development of spike potential mechanisms during cell differentiation was studied in chick myotubes formed in vitro from trypsin-dissociated myoblasts. The spike potential and its rate of rise were measured in myotubes from 4-14 day old cultures. A depolarizing current pulse was delivered to evoke the spike potent...

journal_title：Journal of cellular physiology

authors： Kano M,Yamamoto M

更新日期：1977-03-01 00:00:00