Dauricine induces apoptosis, inhibits proliferation and invasion through inhibiting NF-kappaB signaling pathway in colon cancer cells.

abstract：:Methylglyoxal bis-(guanylhydrazone) (mGBG) blocked the stimulation of DNA synthesis in quiescent, density-inhibited BALB/c-3T3 cells treated with platelet-derived growth factor (PDGF) and platelet-poor plasma (PPP). Competence formation produced by a transient exposure to PDGF was not effected by mGBG. In contrast, mG...

journal_title：Journal of cellular physiology

authors： Wharton W,Van Wyk JJ,Pledger WJ

更新日期：1981-04-01 00:00:00

abstract：:Besides the nerve endings, the soma of trigeminal neurons also respond to membrane depolarizations with the release of neurotransmitters and neuromodulators in the extracellular space within the ganglion, a process potentially important for the cross-communication between neighboring sensory neurons. In this study, we...

journal_title：Journal of cellular physiology

authors： Sforna L,Franciolini F,Catacuzzeno L

更新日期：2019-07-01 00:00:00

abstract：:We have described recently that expression of CD44 exon v10 (CD44v10) is down-regulated upon metastasis of squamous cell carcinoma, whereas it is up-regulated in skin metastases of malignant melanoma. The striking regulation of CD44v10 prompted us to generate a murine CD44v10-specific monoclonal antibody to define exp...

journal_title：Journal of cellular physiology

authors： Rösel M,Seiter S,Zöller M

更新日期：1997-06-01 00:00:00

abstract：:Two important mediators of endothelium-dependent regulation of vascular smooth muscle tone and proliferation are nitric oxide (NO) and endothelin (ET-1). An imbalance between NO and ET-1 may contribute to the alterations in vascular tone characteristic of cardiovascular disease. The objective of this study was to dete...

journal_title：Journal of cellular physiology

authors： Redmond EM,Cahill PA,Hodges R,Zhang S,Sitzmann JV

更新日期：1996-03-01 00:00:00

abstract：:The mammalian olfactory system is a physiologically plastic region of the brain with the potential to support implanted stem cells. We performed direct injection of lineage-negative (lin-neg), green fluorescent protein-positive (GFP+) bone marrow cells into the olfactory bulb to assess cell survival and motility withi...

journal_title：Journal of cellular physiology

authors： Moore BE,Colvin GA,Dooner MS,Quesenberry PJ

更新日期：2005-01-01 00:00:00

abstract：:Acute lung injury, sepsis, lung inflammation, and ventilator-induced lung injury are life-threatening conditions associated with lung vascular barrier dysfunction, which may lead to pulmonary edema. Increased levels of atrial natriuretic peptide (ANP) in lung circulation reported in these pathologies suggest its poten...

journal_title：Journal of cellular physiology

authors： Birukova AA,Zagranichnaya T,Alekseeva E,Bokoch GM,Birukov KG

更新日期：2008-06-01 00:00:00

abstract：:Previous studies suggested that the decreased collagen production observed in Kirsten sarcoma virus (Ki-MSV)-transformed BALB 3T3 cells could be reversed by treating cells with Bt2cAMP. We examined the relationship between intracellular cAMP, collagen production, and other properties in NRK and BALB 3T3 cells transfor...

journal_title：Journal of cellular physiology

authors： Majmudar G,Peterkofsky B

更新日期：1985-01-01 00:00:00

abstract：:A process of unconventional secretion that is dependent on the Golgi stacking protein GRASP and multiple components of the autophagy machinery has recently been documented for several cytoplasmic and membrane protein. Classical secretion via the exocytic pathway is inhibited during cell division in animal cells, as ke...

journal_title：Journal of cellular physiology

authors： Tang BL

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:This study aimed to explore the underlying function of Gubenxiezhuo dialysis on the distribution of gut microflora uremia. METHODS:A uremia rat model was constructed, and the morphology of renal tissue was determined using the hematoxylin-eosin (H&E) staining. Moreover, the blood samples were collected and t...

journal_title：Journal of cellular physiology

authors： He H,Hu P,Tang Y,Xu X

更新日期：2019-07-01 00:00:00

abstract：:CSF-1 is a hemopoietic growth factor that specifically regulates the survival, proliferation, and differentiation of mononuclear phagocytic cells. Populations of adherent bone marrow-derived macrophages (BMM) devoid of CSF-1 producing cells were used to study regulation by CSF-1 of macrophage entry into S phase. More ...

journal_title：Journal of cellular physiology

authors： Tushinski RJ,Stanley ER

更新日期：1985-02-01 00:00:00

abstract：:Trypsinized normal rat embryo fibroblasts and untrypsinized and trypsinized transformed rat fibroblasts have two orders of binding sites for bacterial glycolipid mR595. The high order sites fix 1--3 micrograms glycolipid mR595/10(5) cells and those of the low order fix about 6 microgram glycolipids mR595/10(6) cells. ...

journal_title：Journal of cellular physiology

authors： Lallier R,Trudel M,Brailovsky CA,Nigam VN

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:Surgical stress has been suggested to facilitate colon cancer growth and metastasis. However, the precise mechanisms by which surgical trauma promotes colon cancer progression remain poorly understood. METHODS:To unravel the mechanisms underlying surgery-induced colon cancer progression, a syngenic transpla...

journal_title：Journal of cellular physiology

authors： Sun Z,Du C,Xu P,Miao C

更新日期：2019-04-01 00:00:00

abstract：:Rat embryo fibroblasts were grown in medium containing 14C-leucine and 3H-thymidine. After a 24-hour chase in nonlabeled medium, cultures were placed in either fresh growth medium or medium containing 10-20 microgram/ml cycloheximide. Cell monolayers were processed at daily intervals for three days. Four hours prior t...

journal_title：Journal of cellular physiology

authors： Amenta JS,Sargus MJ,Baccino FM

更新日期：1978-12-01 00:00:00

abstract：:Epidermal growth factor (EGF) has been shown rapidly to inhibit the transition from G2 phase to mitosis: beyond this transition point the cells are refractory to EGF (Kinzel et al., 1990, Cancer Res., 50:7932-7936). Using synchronized HeLa cells, EGF has now been shown to induce an overall decrease of the histone H1 k...

journal_title：Journal of cellular physiology

authors： Barth H,Kinzel V

更新日期：1995-01-01 00:00:00

abstract：:Glucose deprivation, a pathophysiological cell condition, causes up-regulation of GRP78 and induction of etoposide resistance in human cancer cells. The induction of drug resistance can be partly explained by the fact that GRP78 can block activation of caspase-7 induced by treatment with etoposide. Therefore, downregu...

journal_title：Journal of cellular physiology

authors： Hwang JH,Kim JY,Cha MR,Ryoo IJ,Choo SJ,Cho SM,Tsukumo Y,Tomida A,Shin-Ya K,Hwang YI,Yoo ID,Park HR

更新日期：2008-04-01 00:00:00

abstract：:The trigger for bone remodeling is bone resorption by osteoclasts. Osteoclast differentiation only occurs on the old bone, which needs to be repaired under physiological conditions. However, uncontrolled bone resorption is often observed in pro-inflammatory bone diseases, such as rheumatoid arthritis. Mature osteoclas...

journal_title：Journal of cellular physiology

authors： Matsuura T,Ichinose S,Akiyama M,Kasahara Y,Tachikawa N,Nakahama KI

更新日期：2017-07-01 00:00:00

abstract：:We have modified a method (Gilles et al: Anal. Biochem., 159:109-113, 1986) for measuring cell number, that is based on the binding of crystal violet to cell nuclei and used it to assay effects of various glycosaminoglycans on growth of human lung fibroblasts. The procedure was modified by growing cells in microcultur...

journal_title：Journal of cellular physiology

authors： Westergren-Thorsson G,Onnervik PO,Fransson LA,Malmström A

更新日期：1991-06-01 00:00:00

abstract：:Recently, ATP has gained much interest as an extracellular messenger involved in the communication of calcium signals between cells. The mechanism of ATP release is, however, still a matter of debate. In the present study we investigated the possible contribution of connexin hemichannels or ion channels in the release...

journal_title：Journal of cellular physiology

authors： Braet K,Aspeslagh S,Vandamme W,Willecke K,Martin PE,Evans WH,Leybaert L

更新日期：2003-11-01 00:00:00

abstract：:We have previously observed major differences in the phosphorylation of membrane proteins in sparse, proliferating versus confluent, quiescent pig aortic endothelial cells (EC) (Kazlauskas and DiCorleto, 1987). In the present study we examined whether EC growth state can influence the activity of a specific phosphoryl...

journal_title：Journal of cellular physiology

authors： Uratsuji Y,DiCorleto PE

更新日期：1988-09-01 00:00:00

abstract：:Increased neovascularization is commonly observed in hemorrhagic plaques and associated with rupture of atherosclerotic lesions. This study aims to investigate whether hemin accumulated at the site of hematoma promotes neovascularization through affecting the growth and function of endothelial progenitor cells (EPCs) ...

journal_title：Journal of cellular physiology

authors： Wang JY,Lee YT,Chang PF,Chau LY

更新日期：2009-06-01 00:00:00

abstract：:The catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) is a pleiotropic enzyme involved in DNA repair, cell cycle control, and transcription regulation. A potential role for DNA-PKcs in the regulation of osteoblastogenesis remains to be established. We show that pharmacological inhibition of DNA-PKcs kinase ...

journal_title：Journal of cellular physiology

authors： Farhat T,Dudakovic A,Chung JH,van Wijnen AJ,St-Arnaud R

更新日期：2021-02-01 00:00:00

abstract：:We recently reported that peptidoglycan (PGN), a cell wall component of the Gram-positive bacterium, induces NF-κB activation and microglia activation. However, PGN-regulated AP-1 activation and cytokine expression in microglia remains unclear. This study investigated how PGN influences the signaling pathway involved ...

journal_title：Journal of cellular physiology

authors： Lin HY,Tang CH,Chen JH,Chuang JY,Huang SM,Tan TW,Lai CH,Lu DY

更新日期：2011-06-01 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDAC) is one of the most frequently diagnosed cancers and the fourth leading cause of cancer-related death in the United States, suggesting that there is an urgent need to design novel strategies for achieving better treatment outcome of patients diagnosed with PDAC. Our previous stud...

journal_title：Journal of cellular physiology

authors： Wang Z,Ali S,Banerjee S,Bao B,Li Y,Azmi AS,Korc M,Sarkar FH

更新日期：2013-03-01 00:00:00

abstract：:Glycochenodeoxycholate (GCDA) is closely associated with carcinogenesis and chemoresistance of hepatocellular carcinoma (HCC). Signal transducer and activator of transcription 3 (STAT3), a transcription factor, is involved in various human tumors. Whether GCDA induces chemoresistance through STAT3 and the mechanism of...

journal_title：Journal of cellular physiology

authors： Wang J,Zhou M,Jin X,Li B,Wang C,Zhang Q,Liao M,Hu X,Yang M

更新日期：2020-03-01 00:00:00

abstract：:The polyphenolic compounds curcumin and quercetin increased sensitivity of ovarian cancer cells (CAOV3 and SKOV3) to cisplatin. The effect was obtained when the compounds were added simultaneously with cisplatin, as well as when they were added 24 h before. High serum levels of certain cytokines, for example interleuk...

journal_title：Journal of cellular physiology

authors： Chan MM,Fong D,Soprano KJ,Holmes WF,Heverling H

更新日期：2003-01-01 00:00:00

abstract：:Lung diseases are major cause of morbidity and mortality worldwide. The progress in regenerative medicine and stem cell research in the lung are currently a fast-growing research topic that can provide solutions to these major health problems. Under normal conditions, the rate of cellular proliferation is relatively l...

journal_title：Journal of cellular physiology

authors： Zhu Y,Chen X,Yang X,El-Hashash A

更新日期：2018-10-01 00:00:00

abstract：:Ganoderma lucidum immunomodulatory protein (FIP-glu) is an active ingredient with potential immunoregulatory functions. The study was conducted to explore the immunomodulatory activities of recombinant FIP-glu (rFIP-glu) and its possible mechanism in macrophage RAW264.7 cells. In vitro assays of biological activity in...

journal_title：Journal of cellular physiology

authors： Li QZ,Chang YZ,He ZM,Chen L,Zhou XW

更新日期：2019-12-01 00:00:00

abstract：:Interleukin (IL)-18 is a pro-inflammatory cytokine belonging to the IL-1 family, first identified for its interferon-γ-inducing properties. IL-18 regulates both T helper (Th) 1 and Th2 responses. It acts synergistically with IL-12 in the Th1 paradigm, whereas with IL-2 and without IL-12 it can induce Th2 cytokine prod...

journal_title：Journal of cellular physiology

authors： Vecchié A,Bonaventura A,Toldo S,Dagna L,Dinarello CA,Abbate A

更新日期：2021-03-01 00:00:00

abstract：:Generation of fully functional hematopoietic multipotent progenitor (MPP) cells from human pluripotent stem cells (hPSCs) has a great therapeutic potential to provide an unlimited cell source for treatment of hematological disorders. We previously demonstrated that CD34(+) CD31(+) CD144(+) population derived from hPSC...

journal_title：Journal of cellular physiology

authors： Bai H,Liu Y,Xie Y,Hoyle DL,Brodsky RA,Cheng L,Cheng T,Wang ZZ

更新日期：2016-05-01 00:00:00

abstract：:Intratympanic injection of gentamicin has proven to be an effective therapy for intractable vestibular dysfunction. However, most studies to date have focused on the cochlea, so little is known about the distribution and uptake of gentamicin by the counterpart of the auditory system, specifically vestibular hair cells...

journal_title：Journal of cellular physiology

authors： Qian X,He Z,Wang Y,Chen B,Hetrick A,Dai C,Chi F,Li H,Ren D

更新日期：2020-12-23 00:00:00