Grading acute graft-versus-host disease: time to reconsider.

Abstract:

:Acute graft-versus-host disease (GVHD) is a common and serious complication of allogeneic blood and marrow transplantation. Acute GVHD is commonly graded according to modified Glucksberg criteria. There is considerable within-grade heterogeneity with different patterns of skin, liver, or gut involvement. In this commentary, we provide an analytical review of ambiguities in acute GVHD severity scoring and offer specific proposals meant to generate discussion in the BMT community for adoption, refinement, and where appropriate, validation studies.

journal_name

Pediatr Transplant

authors

Goyal RK,Goyal M,Sankaranarayan K

doi

10.1111/petr.12433

subject

Has Abstract

pub_date

2015-05-01 00:00:00

pages

252-4

issue

3

eissn

1397-3142

issn

1399-3046

journal_volume

19

pub_type

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