Parental functioning improves the developmental quotient of pediatric liver transplant recipients.

abstract：:Dysregulation of genes involved in the cell cycle such as TP53, P21, P16, and PTEN plays a key role in oncogenesis. We have earlier reported increased expression of the TP53 encoded protein p53, in bone marrow samples from pediatric patients with more aggressive, rare chronic myeloid malignancies. The aim of this stud...

journal_title：Pediatric transplantation

authors： Mattsson K,Honkaniemi E,Barbany G,Gustafsson B

更新日期：2015-11-01 00:00:00

abstract：:Pharmacokinetic studies in adult and pediatric liver transplant recipients have shown that the C(2) monitoring is superior to the traditional determination of CsA trough levels (C(0)) as an estimate of CsA exposure. However, target reference values for C(2) in very small infants have not been established yet. The obje...

journal_title：Pediatric transplantation

authors： Ganschow R,Richter A,Grabhorn E,Schulz A,von Hugo A,Mir TS,Broering DC,Rogiers X,Hinrichs B,Burdelski M

更新日期：2004-04-01 00:00:00

abstract：:De novo PTAID may develop in pediatric solid organ transplant recipients, have a diverse spectrum, and are occasionally treatment resistant. Previous reports showed resolution of immune cytopenias in solid organ transplant recipients following replacement of the calcineurin inhibitor tacrolimus with the mTOR inhibitor...

journal_title：Pediatric transplantation

authors： Kehar M,Grunebaum E,Jimenez-Rivera C,Mozer-Glassberg Y,Jamal A,Ng VL,Avitzur Y

更新日期：2020-09-01 00:00:00

abstract：:The waiting period for an organ transplant has been described as a time of tremendous uncertainty and vulnerability, posing unique challenges and stressors for pediatric transplant candidates and their families. It has been identified as the most stressful stage of the transplant journey, yet little attention has been...

journal_title：Pediatric transplantation

authors： Anthony SJ,Annunziato RA,Fairey E,Kelly VL,So S,Wray J

更新日期：2014-08-01 00:00:00

abstract：:Tacrolimus-based immunosuppression in pediatric liver transplant recipients is known to be associated with EGID. Our goal was to determine the incidence, risk factors, and characteristics of EGID in our pediatric liver transplantation program. This study was a retrospective analysis of 38 pediatric liver transplant re...

journal_title：Pediatric transplantation

authors： Lee JH,Park HY,Choe YH,Lee SK,Lee SI

更新日期：2007-08-01 00:00:00

abstract：:Treatment of severe aplastic anemia (SAA) patients who lack human leukocyte antigen (HLA)-matched donors and failed immunosuppressive therapy (IST) is challenging. Recently, umbilical cord blood transplantation (CBT) after non-myeloablative therapy has been reported in adult but not in childhood SAA. However, most cas...

journal_title：Pediatric transplantation

authors： Ohga S,Ichino K,Goto K,Hattori S,Nomura A,Takada H,Nakamura K,Hara T

更新日期：2006-06-01 00:00:00

abstract：:Rabbit antithymocyte globulin (ATG-F) is an extensively used induction agent. To our knowledge, no study to date has assessed reduced ATG-F dosage in children undergoing renal transplantation. This was a retrospective analysis of pediatric renal recipients in the Department of Kidney Transplantation, The First Affilia...

journal_title：Pediatric transplantation

authors： Shang W,Feng G,Gao S,Wang Z,Pang X,Li J,Liu L,Feng Y,Xie H,Zhang S,Qiao B

更新日期：2014-05-01 00:00:00

abstract：:Immunosuppression regimens after liver transplantation focus mainly on preventing rejection and subsequent graft loss. However, in children, morbidity and mortality rates from infections exceed those from rejection after transplant, and immunosuppression can hinder growth, renal function, and graft tolerance. We hypot...

journal_title：Pediatric transplantation

authors： Turmelle YP,Nadler ML,Anderson CD,Doyle MB,Lowell JA,Shepherd RW

更新日期：2009-08-01 00:00:00

abstract：:Plasma cell-rich acute cellular rejection of a transplanted kidney is described in association with the identification of serum antibody to the red cell Kidd antigen, Jk-b, which is also found in the kidney. This antibody was formed without a history of a recent blood transfusion or exposure to intravenous immunoglobu...

journal_title：Pediatric transplantation

authors： Hamilton MS,Singh V,Warady BA

更新日期：2006-12-01 00:00:00

abstract：:BK DNAemia in renal transplant recipients is a significant cause of allograft dysfunction and can lead to graft loss due to BK polyomavirus-associated nephropathy or to graft rejection due to immunosuppression reduction. Currently, the first-line treatment for BK DNAemia is immunosuppression reduction. Second-line tre...

journal_title：Pediatric transplantation

authors： Piburn KH,Al-Akash S

更新日期：2020-02-01 00:00:00

abstract：:The Nordic Pediatric Renal Transplant Study Group was organized in 1994 to register and follow children under 16 years of age who receive renal allografts in the Nordic countries. It comprises all transplant centers in Scandinavia, four in Sweden, three in Denmark and one each in Norway and Finland. The following repo...

journal_title：Pediatric transplantation

authors： Tydén G,Berg U

更新日期：1998-08-01 00:00:00

abstract：:Obscure gastrointestinal (GI) bleeding is defined as bleeding from the GI tract that persists or recurs, with no obvious etiology, after esophagogastroduodenoscopy (EGD), colonoscopy, and radiologic evaluation of the small bowel. We present the case of a 17-yr-old girl who for two years had been suffering from recurre...

journal_title：Pediatric transplantation

authors： Curcio G,Sciveres M,Mocciaro F,Riva S,Spada M,Tarantino I,Barresi L,Traina M

更新日期：2012-05-01 00:00:00

abstract：:An 18-yr-old Hispanic female with end-stage renal disease secondary to chronic glomerulonephritis of unknown etiology underwent cadaveric renal transplantation. She was placed on a steroid-free protocol with tacrolimus and mycophenolate mofetil (MMF) for maintenance immunosuppression. Approximately 8 months post-trans...

journal_title：Pediatric transplantation

authors： Nagarajan S,Friedrich T,Garcia M,Kambham N,Sarwal MM

更新日期：2005-02-01 00:00:00

abstract：:aHUS is caused by the over-activation and dysregulation of the alternative complement pathway. Data regarding outcomes of pediatric aHUS patients after kidney transplantation are still very scarce. Accordingly, the aim of this study was to describe the clinical findings and outcomes of pediatric aHUS patients after re...

journal_title：Pediatric transplantation

authors： Özçakar ZB,Ozaltin F,Gülhan B,Çomak E,Parmaksız G,Baskın E,Topaloğlu R,Kasap Demir B,Canpolat N,Yuruk Yildirim Z,Demircioğlu Kılıç B,Yüksel S,Söylemezoğlu O

更新日期：2020-11-20 00:00:00

abstract：:T1D is an autoimmune disease, which may be caused by lack of insulin-secreting β cells due to damage of autoimmune system. Living with T1D is a challenge for the child and the family; cell transplantation is a treatment option for diabetes in children. To establish a microenvironment suitable for cell growth and proli...

journal_title：Pediatric transplantation

authors： Yuan X,Huang Y,Guo Y,Wang L,Guo Q,Xu T,Wu D,Zhou P,Zhu S,Wang Y,Fan X,Zhu M,Lu Y,Wang Z

更新日期：2015-06-01 00:00:00

abstract：:Autoimmune and allergic diseases cause morbidity and diminished quality of life in pediatric organ transplant recipients. We hypothesize that younger age at transplantation and immunosuppression regimen play a role in the development of immune-mediated disease following heart transplant. A single institution retrospec...

journal_title：Pediatric transplantation

authors： Mouledoux JH,Albers EL,Lu Z,Saville BR,Moore DJ,Dodd DA

更新日期：2014-03-01 00:00:00

abstract：:We report on survival, rejection, lymphoma and renal function following cardiac transplant using a steroid-free maintenance immunosuppressive regimen. We have performed 73 cardiac transplants in 71 children under 16 yr of age in the last 12 yr. There were eight perioperative and four late deaths giving actuarial survi...

journal_title：Pediatric transplantation

authors： Leonard H,Hornung T,Parry G,Dark JH

更新日期：2003-02-01 00:00:00

abstract：:SAB assays have increased the sensitivity and specificity to detect HLA alloantibodies, but there is uncertainty about the clinical relevance of SAB-positive alloantibodies when the FCXM is negative. We performed a retrospective study to evaluate the clinical significance of SAB-detected DSA in 82 pediatric recipients...

journal_title：Pediatric transplantation

authors： Verghese PS,Smith JM,McDonald RA,Schwartz SM,Nelson KA,Warner PR

更新日期：2010-09-01 00:00:00

abstract：:The aim of this study was to study the incidence of chronic renal dysfunction in patients with more than 5 yr of follow-up following liver transplantation and to evaluate the benefit of decreasing cyclosporine A (CsA) dose combined with mycophenolate mofetil (MMF) on renal function and immune response in these patient...

journal_title：Pediatric transplantation

authors： Ferraris JR,Duca P,Prigoshin N,Tambutti ML,Boldrini G,Cardoni RL,D'Agostino D

更新日期：2004-10-01 00:00:00

abstract：:There is increasing evidence that DSA are associated with poor graft survival, although there are little data in children. We aimed to describe the incidence of DSA in this group and to determine correlation with graft survival. HLA antibodies were analysed in 59 paediatric cardiac transplant recipients. Mean age 10.4...

journal_title：Pediatric transplantation

authors： Irving C,Carter V,Parry G,Hasan A,Kirk R

更新日期：2011-03-01 00:00:00

abstract：:Drowning, a common cause of death in the pediatric population, is a potentially large donor pool for OLT. Anecdotally, transplant centers have deemed these organs high risk over concerns for infection and graft dysfunction. We theorized drowned donor liver allografts do not portend worse outcomes and therefore should ...

journal_title：Pediatric transplantation

authors： Kumm KR,Galván NTN,Koohmaraie S,Rana A,Kueht M,Baugh K,Hao L,Yoeli D,Cotton R,O'Mahony CA,Goss JA

更新日期：2017-09-01 00:00:00

abstract：:Antibody-mediated rejection (AMR) has recently been recognized as a significant and unique form of rejection that is not amenable to treatment with standard immunosuppressive medications aimed at modification of T-cell function. Recent interest in AMR and the role of B cells in rejection has been aided by the concomit...

journal_title：Pediatric transplantation

authors： Jordan SC,Vo AA,Tyan D,Nast CC,Toyoda M

更新日期：2005-06-01 00:00:00

abstract：:The relationship between SES and outcomes surrounding pediatric cardiac transplantation is complex and influenced by recipient race. Broad-based studies of SES have not been performed. A retrospective review of all 5125 primary pediatric heart transplants performed in the United States between 2000 and 2011. Patients ...

journal_title：Pediatric transplantation

authors： Davies RR,Russo MJ,Reinhartz O,Maeda K,Rosenthal DN,Chin C,Bernstein D,Mallidi HR

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:With an increasing number of heart transplantations (HTx) performed in children and an extended long-term survival of these patients, the importance of transplant coronary artery disease (TCAD) rises in this group of transplant recipients. Reliable serum markers for diagnosis or non-invasive monitoring of th...

journal_title：Pediatric transplantation

authors： Hilgendorff A,Kraemer U,Afsharian M,Bauer J,Tillmanns H,Kemkes-Matthes B,Kreuder J,Hoelschermann H

更新日期：2006-06-01 00:00:00

abstract：:Children who develop end-stage renal disease (ESRD) as a result of obstructive uropathies require evaluation and treatment of associated bladder dysfunction to ensure a good outcome following renal transplantation. Bladder dynamics can often be optimized medically, although surgical intervention is occasionally necess...

journal_title：Pediatric transplantation

authors： Kurzrock EA,Butani L,Kakker SP,Perez RV,Lavjay Butani.

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:The hybrid stage 1 palliation for hypoplastic left heart syndrome (HLHS) was first described in 1993 as a bridge to heart transplant for HLHS. There are limited data on this strategy as primary heart transplantation for HLHS has become less common. METHODS:This is an observational, single-center study compa...

journal_title：Pediatric transplantation

authors： Morray BH,Albers EL,Jones TK,Kemna MS,Permut LC,Law YM

更新日期：2018-12-01 00:00:00

abstract：:Nephrotic syndrome is characterized by proteinuria, hypoalbuminemia, and general edema. These symptoms may persist in children who reach ESRD, which is unfavorable for the patient's allograft outcome. In addition, this may hamper early diagnosis of a relapse after transplantation. Surgical bilateral nephrectomy is oft...

journal_title：Pediatric transplantation

authors： Vos E,Koster-Kamphuis L,van de Kar NCAJ,Bootsma-Robroeks CMHHT,Cornelissen EAM,Schreuder MF

更新日期：2020-06-01 00:00:00

abstract：:Stenosis of the HJ is a common complication of pediatric split LT with high morbidity and possible evolution to secondary biliary cirrhosis and re-transplantation if not treated. Because the endoscopy is generally infeasible in the Roux-en-Y, percutaneous interventional radiology management is usually the safest and m...

journal_title：Pediatric transplantation

authors： Paolantonio G,Pietrobattista A,Parapatt GK,Liccardo D,Natali GL,Candusso M,Spada M,Rollo M,Tomà P

更新日期：2018-12-01 00:00:00

abstract：:HSCT has substantially improved pediatric acquired SAA patients' outcomes. Retrospectively, we attempted to assess the outcome of MRD HSCT in 65 pediatric patients referred to a single center from 1992 to 2012. We were particularly interested to find out whether source of SC (PB, n = 40 and BM, n = 25) significantly i...

journal_title：Pediatric transplantation

authors： Hamidieh AA,Mozafari M,Noshad S,Alimoghaddam K,Behfar M,Ghavamzadeh A

更新日期：2015-06-01 00:00:00

abstract：:This report describes a successful renal Tx in a patient with chronic renal failure, caused by dysplastic kidneys, who received a cadaveric kidney with post-infectious glomerulonephritis. Sequential renal biopsies were performed at 12 h before Tx, and at 1 h and on days 8 and 58 post-Tx. Post-operative hematuria disap...

journal_title：Pediatric transplantation

authors： Mizuiri S,Shigetomi Y,Sugiyama K,Miyagi M,Hatano T,Tajima E,Aikawa A,Ohara T,Kawamura S,Hasegawa A

更新日期：2000-02-01 00:00:00