C2 blood concentrations of orally administered cyclosporine in pediatric liver graft recipients with a body weight below 10 kg.

abstract：:Secondary failure of platelet engraftment occurs in 20% of patients undergoing allogeneic HSCT and is associated with poor outcome. Currently, there are no guidelines for treatment of late thrombocytopenia and platelet transfusion is the mainstay of treatment. Here, we describe the use of Eltrombopag to treat secondar...

journal_title：Pediatric transplantation

authors： Ali S,Gassas A,Kirby-Allen M,Krueger J,Ali M,Schechter T

更新日期：2017-09-01 00:00:00

abstract：:Immunosuppression regimens after liver transplantation focus mainly on preventing rejection and subsequent graft loss. However, in children, morbidity and mortality rates from infections exceed those from rejection after transplant, and immunosuppression can hinder growth, renal function, and graft tolerance. We hypot...

journal_title：Pediatric transplantation

authors： Turmelle YP,Nadler ML,Anderson CD,Doyle MB,Lowell JA,Shepherd RW

更新日期：2009-08-01 00:00:00

abstract：:The availability of new and more effective anti-rejection therapy has succeeded in reducing the incidence of acute cellular rejection in first months post-renal transplant. This in turn has escalated the order of significance of recurrence of primary disease in the renal allograft as a cause for patient morbidity and ...

journal_title：Pediatric transplantation

authors： Seikaly MG

更新日期：2004-04-01 00:00:00

abstract：:This retrospective case series reviews our center's experience with sirolimus and a CNI as alternative therapy for the treatment of PTAH. It also characterizes regulatory T cells (Tregs) in PTAH. LT recipients with PTAH who had received or were receiving treatment with sirolimus were retrospectively identified (n = 12...

journal_title：Pediatric transplantation

authors： Ekong UD,Mathew J,Melin-Aldana H,Wang D,Alonso EM

更新日期：2012-03-01 00:00:00

abstract：:Despite the fact that non-adherence to medical therapy is one of the major causes of late morbidity and mortality in pediatric liver transplant recipients, little is known of the risk factors involved in this behavior. Three cases of fatal non-adherence are reported. Factors associated with non-adherence were investig...

journal_title：Pediatric transplantation

authors： Lurie S,Shemesh E,Sheiner PA,Emre S,Tindle HL,Melchionna L,Shneider BL

更新日期：2000-08-01 00:00:00

abstract：:Combined enzyme replacement therapy (ERT) and stem cell transplant (SCT) were done for a two year old boy with severe Hurler syndrome(HS) with the aim to decrease transplant related complications. He tolerated both the procedures well without any major complications. Urine glycosaminoglycans (GAGs) decreased post-tran...

journal_title：Pediatric transplantation

authors： Soni S,Hente M,Breslin N,Hersh J,Whitley C,Cheerva A,Bertolone S

更新日期：2007-08-01 00:00:00

abstract：:UCBT recipients with TM are at high risk of EF related to low number of stem cells and prior alloimmunization after multiple blood transfusions. Here, we evaluated the safety and efficacy of double-unit UCBT using TT-containing conditioning regimens in TM. Retrospective analysis of children who underwent double-unit U...

journal_title：Pediatric transplantation

authors： Feng J,Lee V,Leung AWK,Lam GKS,Chow TTW,Cheng FWT,Yan CLS,Lee CK,Yuen PMP,Li CK

更新日期：2020-11-02 00:00:00

abstract：:This single-centre, retrospective, observational pilot study was performed to evaluate the safety and efficacy of intravenous and oral itraconazole prophylaxis in paediatric haematopoietic stem cell transplantation (HCT). Study end-points were proven invasive fungal infection (IFI), survival, adverse reactions and gra...

journal_title：Pediatric transplantation

authors： Grigull L,Kuehlke O,Beilken A,Sander A,Linderkamp C,Schmid H,Seidemann K,Sykora KW,Schuster FR,Welte K

更新日期：2007-05-01 00:00:00

abstract：:Effective antibody removal using PE, DFPP and IA has led to increased access to live donor organs through ABOi RT for patients with chronic kidney disease. However, there have been no head-to-head comparator studies between these modalities, and the choice of technique is usually influenced by cost and institutional p...

journal_title：Pediatric transplantation

authors： Thalgahagoda S,Webb NJ,Roberts D,Birch A,Milford DV,Tavakoli A,Shenoy M

更新日期：2014-05-01 00:00:00

abstract：:Liver and small bowel transplant is an established treatment for infants with IFALD. Despite organ reduction techniques, mortality on the waiting list remains high due to shortage of size-matched pediatric donors. Small abdominal cavity volume due to previous intestinal resection poses a significant challenge to achie...

journal_title：Pediatric transplantation

authors： Vidyadharan R,van Bommel AC,Kuti K,Gupte GL,Sharif K,Richard BM

更新日期：2013-11-01 00:00:00

abstract：:PMF of infancy is a recently described autosomal recessive disorder presenting with severe bone marrow failure, accelerated neutrophil apoptosis, and significant platelet dysfunction, caused by a mutation in the VPS45 gene. In this study, we update our group of patients with PMF, highlighting different aspects of this...

journal_title：Pediatric transplantation

authors： Stepensky P,Simanovsky N,Averbuch D,Gross M,Yanir A,Mevorach D,Elpeleg O,Weintraub M

更新日期：2013-12-01 00:00:00

abstract：:From June 1985 to December 1998, 173 pediatric renal transplants were carried out in 170 patients at our center. From this pool, 73 patients (34 males and 39 females) with a follow-up of 48 months were examined. In all patients, ureteroneocystostomy was performed according to the Lich-Grégoire procedure. All patients ...

journal_title：Pediatric transplantation

authors： Fontana I,Ginevri F,Arcuri V,Basile G,Nocera A,Beatini M,Bonato L,Barocci S,Bertocchi M,Manolitsi O,Valente R,Draghi P,Gusmano R,Valente U

更新日期：1999-08-01 00:00:00

abstract：:Primary hyperoxalurias are rare inborn errors of metabolism with deficiency of hepatic enzymes that lead to excessive urinary oxalate excretion and overproduction of oxalate which is deposited in various organs. Hyperoxaluria results in serious morbid-ity, end stage kidney disease (ESKD), and mortality if left untreat...

journal_title：Pediatric transplantation

authors： Kotb MA,Hamza AF,Abd El Kader H,El Monayeri M,Mosallam DS,Ali N,Basanti CWS,Bazaraa H,Abdelrahman H,Nabhan MM,Abd El Baky H,El Sorogy STM,Kamel IEM,Ismail H,Ramadan Y,Abd El Rahman SM,Soliman NA

更新日期：2019-02-01 00:00:00

abstract：:Myocarditis represents an important cause for acute heart failure. MYKKE, a prospective multicenter registry of pediatric patients with myocarditis, aims to gain knowledge on courses, diagnostics, and therapy of pediatric myocarditis. The role of mechanical circulatory support (MCS) in children with severe heart failu...

journal_title：Pediatric transplantation

authors： Schubert S,Opgen-Rhein B,Boehne M,Weigelt A,Wagner R,Müller G,Rentzsch A,Zu Knyphausen E,Fischer M,Papakostas K,Wiegand G,Ruf B,Hannes T,Reineker K,Kiski D,Khalil M,Steinmetz M,Fischer G,Pickardt T,Klingel K,Messr

更新日期：2019-11-01 00:00:00

abstract：:NH is the most common identifiable cause of ALF in the neonate. LT is the definitive treatment for neonates with NH who have failed medical therapy. Our aim was to determine the outcomes of LT in infants with NH. Patients (less than one yr of age) with NH who were listed for LT and patients who underwent LT between 19...

journal_title：Pediatric transplantation

authors： Sheflin-Findling S,Annunziato RA,Chu J,Arvelakis A,Mahon D,Arnon R

更新日期：2015-03-01 00:00:00

abstract：:Prematurity and very low birthweight have often been considered relative contraindications to neonatal organ donation. Organ procurement from neonatal donors is further complicated by unclear guidelines regarding neonatal brain death. We report a successful case of multivisceral transplantation using a graft from a 10...

journal_title：Pediatric transplantation

authors： Cauley RP,Suh MY,Kamin DS,Lillehei CW,Jenkins RL,Jonas MM,Vakili K,Kim HB

更新日期：2012-12-01 00:00:00

abstract：:We reviewed 112 pediatric renal transplant recipients to document the rate of medication non-adherence (NA) and to examine the relationships between NA, comorbid psychiatric illness, and the outcome variables of acute and chronic rejection and graft loss. A total of 32.5% of subjects had clinically significant NA with...

journal_title：Pediatric transplantation

authors： Shaw RJ,Palmer L,Blasey C,Sarwal M

更新日期：2003-12-01 00:00:00

abstract：:Pediatric candidates for combined liver/bowel transplant (LBTx) experience a very high mortality on the cadaver waiting list. Our transplant center has successfully used adult living donors to treat pediatric candidates for LBTx. We report the long-term follow-up of this unique cohort of organ donors. The charts of si...

journal_title：Pediatric transplantation

authors： Ghafari JL,Bhati C,John E,Tzvetanov IG,Testa G,Jeon H,Oberholzer J,Benedetti E

更新日期：2011-06-01 00:00:00

abstract：:With small kidneys, EBKTs could provide sufficient renal mass but could lead to inefficient use of resources, while SKTs could result in insufficient function due to small renal mass. We aimed to compare the outcomes of EBKT and SKT from small donors weighing ≤15 kg to pediatric recipients. We retrospectively reviewed...

journal_title：Pediatric transplantation

authors： Mo H,Ko H,Chung CTY,Kim HK,Han A,Min S,Ha J

更新日期：2020-05-06 00:00:00

abstract：:Bartter's syndrome (BS) is an incurable genetic disease, with variable response to supportive therapy relating to fluid and electrolyte management. Poor control or therapy non-compliance may result in frequent life threatening episodes of dehydration, acidosis and hypokalemia, with resultant adverse effects on patient...

journal_title：Pediatric transplantation

authors： Chaudhuri A,Salvatierra O Jr,Alexander SR,Sarwal MM

更新日期：2006-03-01 00:00:00

abstract：:The risk of adverse outcomes for pediatric renal transplant patients is highest during the transition from pediatric to adult care. While there have been many studies focus on graft failure and death, loss to follow-up likely plays a large role in patient outcomes. We hypothesize patients are lost to follow-up during ...

journal_title：Pediatric transplantation

authors： Hung YC,Williams JE,Bababekov YJ,Rickert CG,Chang DC,Yeh H

更新日期：2019-11-01 00:00:00

abstract：:The aim of this study was to re-evaluate the indications and timing of LT for WD. From 2000 to 2009, eight patients with WD who had been referred to our institution for LT were enrolled in this study. The mean patient age was 15.9 yr (range, 7-37 yr). Four patients could not receive LT, because there were no available...

journal_title：Pediatric transplantation

authors： Ohya Y,Okajima H,Honda M,Hayashida S,Suda H,Matsumoto S,Lee KJ,Yamamoto H,Takeichi T,Mitsubuchi H,Asonuma K,Endo F,Inomata Y

更新日期：2013-06-01 00:00:00

abstract：:To date, the evidence upon which a decision is made to transplant a child with acute lymphoblastic leukaemia either in first or subsequent remission has rarely been based on randomized trial data. Modern era management of infection and graft-versus-host disease lessens risks but procedure-related deaths still remain h...

journal_title：Pediatric transplantation

authors： Eden OB

更新日期：1999-01-01 00:00:00

abstract：:This systematic review was designed to find out optimal tacrolimus dose in pediatrics according to their CYP3A5*1 genotype by performing meta-analysis. PubMed, Scopus, ISI web of Science, ProQuest, Cochrane library, and clinicaltrail.gov were systematically searched to find studies in which tacrolimus dose and/or bloo...

journal_title：Pediatric transplantation

authors： Hendijani F,Azarpira N,Kaviani M

更新日期：2018-06-19 00:00:00

abstract：:Sirolimus represents a major advancement in the field of solid organ transplantation and is being used as a rescue agent for acute and chronic rejection as well as for primary immunosuppression with good graft outcome. Although initial studies with sirolimus were in adults, now significant data have accumulated on the...

journal_title：Pediatric transplantation

authors： Gupta P,Kaufman S,Fishbein TM

更新日期：2005-06-01 00:00:00

abstract：:DD kidney allocation protocols may influence timing of transplantation and graft quality for pediatric recipients. This study aimed to evaluate the effects of these protocols, including pediatric priority, on waiting time on dialysis, transplant type, donor age, and HLA matching according to state of transplant in Aus...

journal_title：Pediatric transplantation

authors： Le Page AK,Johnstone LM,Kennedy SE

更新日期：2015-09-01 00:00:00

abstract：:We report a case of arterio-portal fistulae in a 12-month-old-child following a segmental liver transplantation. The fistula, probably the result of mass ligature of a vascular pedicle during back table allograft reduction, is to our knowledge the first such case reported. Diagnosed on the third post-operative day, th...

journal_title：Pediatric transplantation

authors： Mieles LA,Waldman D,Orloff MS

更新日期：2002-10-01 00:00:00

abstract：:Castleman disease is a rare hematologic disorder, closely linked to the HHV-8, and most commonly observed in immunocompromised individuals. Thirteen months following a liver transplant for CPS-1 defect, a 15-month-old boy presented with fevers, anemia, and growth retardation. Abdominal CT scan showed splenomegaly and ...

journal_title：Pediatric transplantation

authors： Bonatti HJ,Axt J,Hunter EB,Lott SL,Frangoul H,Gillis L,Correa H,Kelly B

更新日期：2012-09-01 00:00:00

abstract：:Medical cannabis is now legal in over half of the United States. As more patients adopt this unconventional therapy, it is inevitable that potential transplant recipients will disclose their cannabis use during transplant evaluation. Transplant teams are tasked with the decision to utilize a pressure resource, often w...

journal_title：Pediatric transplantation

authors： Ryan JE,Noeder M,Burke C,Stubblefield SC,Sulieman S,Miller EG

更新日期：2019-08-01 00:00:00

abstract：:HSCT-associated thrombotic microangiopathy (TA-TMA) is a severe complication with a poor prognosis. Recently, it has been reported that complement system dysregulation, such as CFH autoantibodies and deletions CFH-related genes 3 and 1, induced TA-TMA. In addition, C4d-positive renal arterioles are both a good marker ...

journal_title：Pediatric transplantation

authors： Sakamoto K,Imamura T,Osone S,Nishimura A,Nishida M,Ishida H,Hosoi H

更新日期：2015-06-01 00:00:00