Abstract：
:The 'binding' of IgE to particulate preparations derived from sonicated purified rat mast cells was measured by the blocking of PCA titrations of the supernatant solutions from incubations with such preparations. It was found that the PCA blocking reaction was inhibited by the addition of calcium ion to the incubations. The blocking reaction was strongly dependent on the pH of the incubations, being maximal at pH values lower than 5-0. The blocking reaction proceeded in a linear manner for at least 3 h provided that no more than 70 percent of the amount of IgE initially supplied had been removed by the particulate fraction. Only mast cell-derived preparations were capable of effecting PCA blocking.
journal_name
Immunologyjournal_title
Immunologyauthors
Bach MK,Brashler JRsubject
Has Abstractpub_date
1976-01-01 00:00:00pages
101-5issue
1eissn
0019-2805issn
1365-2567journal_volume
30pub_type
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