Novel medical strategies combating nonmelanoma skin cancer.

Abstract:

:The incidence of nonmelanoma skin cancer (NMSC) continues to rise, partly because of aging, the frequency of early childhood sunburns, and sporadic extreme recreational sun exposure. A nonsurgical approach to selected cutaneous malignancy could possibly reduce the cost as well as morbidity of surgical treatment for NMSC. There has been growing interest in isolating compounds that could suppress or reverse the biochemical changes necessary for cutaneous malignancies to progress by pharmacologic intervention. By targeting diverse pathways recognized as important in the pathogenesis of nonmelanoma skin cancers, a combination approach with multiple agents or addition of chemopreventative agents to topical sunscreens may offer the potential for novel and synergistic therapies in treating nonmelanoma skin cancer. This preliminary information will expand to include more therapeutic options for NMSC in the future.

journal_name

Indian J Dermatol

authors

Bhandari PR,Pai VV

doi

10.4103/0019-5154.143503

subject

Has Abstract

pub_date

2014-11-01 00:00:00

pages

531-46

issue

6

eissn

0019-5154

issn

1998-3611

pii

IJD-59-531

journal_volume

59

pub_type

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