Abstract:
BACKGROUND:The ability of steroids to reduce the histamine wheal was used to assess the efficacy of topical clobetasol propionate with varying dilutions of emollients. AIM:To determine the wheal-suppressing ability of topical clobetasol with varying dilutions of emollient. MATERIALS AND METHODS:It was a double-blinded randomized study. Twenty-five volunteers were included in the study. Five syringes of 5 ml were taken and the syringes were loaded with either clobetasol propionate 0.05%, emollient, or clobetasol propionate with emollient in dilutions of 1:1, 1:2, and 1:3. The syringes were coded 1 to 5. Five squares of 3 × 3 cm were marked on the flexor aspect of the forearm of the volunteers. After randomization, half fingertip unit of the cream was applied within each square uniformly. Three hours later histamine prick test was performed by the standard method. The wheal was measured after 15 min and the results were recorded. After decoding, results were statistically analyzed by analysis of variance. RESULT:The decrease in wheal suppression of steroid with emollient (1:1) was same as topical steroid and the wheal suppression decreased with increasing dilutions of steroid. CONCLUSION:We conclude that steroids and emollients can be mixed in equal proportion (1:1) and the effect is same as steroid alone and increasing dilution of steroids with emollients was not effective in suppressing the wheal.
journal_name
Indian J Dermatoljournal_title
Indian journal of dermatologyauthors
Barathi M,Rai R,Srinivas CRdoi
10.4103/0019-5154.87146subject
Has Abstractpub_date
2011-09-01 00:00:00pages
527-8issue
5eissn
0019-5154issn
1998-3611pii
IJD-56-527journal_volume
56pub_type
杂志文章abstract:BACKGROUND:Few clinical studies are found in the literature about patients hospitalized with a diagnosis of cutaneous drug eruption. AIMS:To determine the clinical types of drug eruptions and their causative agents in a hospital-based population. MATERIALS AND METHODS:This retrospective study was performed in the Der...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.96191
更新日期:2012-05-01 00:00:00
abstract::Cellular grafting methods constitute important advances in the surgical management of leucoderma. Different methods such as noncultured epidermal suspensions, melanocyte cultures, and melanocyte-keratinocyte cultures have all been shown to be effective. This article reviews these methods. ...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.53194
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Pilomatrixoma (PMX) is a benign, quite uncommon, skin neoplasm, which is frequently misdiagnosed by clinicians. AIM:We have analyzed 25 PMX to determine the agreement between clinical diagnosis, preoperative FNA characteristics, and corresponding histopathological specimens; moreover, reliable cytologic cri...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.94295
更新日期:2012-03-01 00:00:00
abstract:Background:Chronic spontaneous urticaria (CSU) is a skin disorder with an important immunologic profile. S100A8, S100A9, and S100A12 are the members of S100 family that have been reported to play important role in autoimmune diseases, but the characteristics of these three S100 members have not been defined in CSU. Ai...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/ijd.IJD_375_18
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:Skin tags are common benign skin tumors usually occurring on the neck and major flexors of elder people. AIMS:The aim of this study is to perform quantitation of mast cells and collagen fibers in skin tags and normal skin in diabetics and nondiabetics, to find a possible correlation between mast cells and c...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.57605
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:The mycological study of pityriasis versicolor is usually done by potassium hydroxide (KOH) mount and culture. However, KOH mount lacks a color contrast and requires a trained eye to interpret, while culture is difficult to perform, time consuming and has low sensitivity. Chicago Sky Blue 6B (CSB) is a new c...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.160476
更新日期:2015-07-01 00:00:00
abstract::Acanthosis nigricans (AN) is a dermatosis characterized by velvety, papillomatous, brownish-black, hyperkeratotic plaques, typically on the intertriginous surfaces and neck. The majority (80%) of AN occurs idiopathically or in benign conditions such as endocrinopathies like diabetes mellitus, polycystic ovary syndrome...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
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abstract::A case of tuberculosis verrucosa cutis in an unusual site is being reported. The patient had presented with recurrence of a perianal growth which had been excised in the past. A histopathological study done during the recurrence confirmed tuberculosis. The patient's chest X-ray showed pulmonary tuberculosis, though he...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:
更新日期:1989-03-01 00:00:00
abstract:BACKGROUND:In the present study, calcinosis cutis (CC) is defined as the deposition of amorphous calcium and phosphate salts under epidermis and it may be caused by a pre-existing event such as extravasation injury or hypercalcemic conditions. Idiopathic CC cases have no underlying disease or pre-existing cause. AIM:A...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.119960
更新日期:2013-11-01 00:00:00
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journal_title:Indian journal of dermatology
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更新日期:2015-01-01 00:00:00
abstract:Background:Chronic urticaria is a common dermatological disorder that causes a great deal of distress in patients and affects daily life. Narrow band ultraviolet B (NBUVB) has been shown to be an effective treatment in chronic urticaria in few studies. However, the data regarding its role in chronic urticaria are limit...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
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更新日期:2019-05-01 00:00:00
abstract::Cutaneous leiomyomas are benign tumors derived from the smooth muscles of the skin. They are firm, skin-colored to brownish, frequently painful papules and nodules presenting either as a solitary tumor or multiple clustered lesions. Uncommon patterns of multiple leiomyoma cutis include linear, zosteriform, or dermatom...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.156388
更新日期:2015-05-01 00:00:00
abstract::Erythema annulare centrifugum (EAC) is characterised by slowly enlarging annular erythematous lesions and is thought to represent a clinical reaction pattern to infections, medications, and rarely, underlying malignancy. Causative drugs include chloroquine, cimetidine, gold sodium thiomalate, amitriptyline, finasterid...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/ijd.IJD_728_16
更新日期:2018-01-01 00:00:00
abstract::A wide prevalence of socio-religious and cultural practices in the Asian subcontinent often leads to multitude of skin diseases which may be missed by the dermatologists because of a lack of awareness. 'Henna' use causes IgE-mediated hypersensitivity reactions and contact dermatitis. 'Kumkum' application can result in...
journal_title:Indian journal of dermatology
pub_type: 杂志文章,评审
doi:10.4103/0019-5154.147778
更新日期:2015-01-01 00:00:00
abstract::A systematic review is a summary of existing evidence that answers a specific clinical question, contains a thorough, unbiased search of the relevant literature, explicit criteria for assessing studies and structured presentation of the results. A systematic review that incorporates quantitative pooling of similar stu...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.127671
更新日期:2014-03-01 00:00:00
abstract:UNLABELLED:Vitiligo is a common skin disorder, and the pathogenesis is unknown. An increased prevalence of autoimmune thyroid diseases has been described in these patients. The aim of this study is to assess the prevalence of thyroid dysfunction and hypoparathyroidism in patients with vitiligo. MATERIALS AND METHODS:O...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.39733
更新日期:2008-01-01 00:00:00
abstract::Psoriasiform dermatoses often pose challenges to both dermatologists and pathologists alike. With proper clinicopathologic correlation and a systematic approach, it is possible to arrive at a specific diagnosis in most cases. This article attempts to outline a practical, step-wise method of looking at these cases and ...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.113945
更新日期:2013-07-01 00:00:00
abstract:INTRODUCTION:Hand, foot, and mouth disease (HFMD), an enteroviral disease has emerged as a major emerging infection in India. This is caused most commonly by enterovirus 71 (EV71) and coxsackievirus A16 (CVA16) but can also be due to CVA4-10, CVA24, CVB2-5, and echovirus 18 (Echo18). Virological analysis of the cases o...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/ijd.IJD_381_17
更新日期:2017-09-01 00:00:00
abstract::A 55-year-old woman presented with a 5-year history of livedo racemosa on her limbs. Histology showed vasculitis of medium-sized arteries with a circumferential, hyalinised, intraluminal fibrin ring. Her laboratory investigations did not indicate any underlying systemic disease. The findings were consistent with lymph...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.139907
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND:Acanthosis nigricans (AN) is a dermatosis characterized by thickened, hyperpigmented plaques, typically on the intertriginous surfaces and neck. Common in some populations, its prevalence depends on race. Clinicians should recognize AN; it heralds disorders ranging from endocrinologic disturbances to maligna...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.91828
更新日期:2011-11-01 00:00:00
abstract::In genetically and phenotypically heterogeneous conditions like ichthyosis, it is clinically not possible to predict mutation in a specific gene. Sequential testing of all the causative genes is time consuming and expensive. In consanguineous families with autosomal recessive genetically heterogeneous disorders, it is...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
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更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Existing remedies for controlling pseudofolliculitis barbae (PFB) are sometimes helpful; however the positive effects are often short lived. The only definitive cure for PFB is permanent removal of the hair follicle. AIMS:Our aim was to compare the efficacy of the Alexandrite laser with the intense pulsed l...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.57615
更新日期:2009-01-01 00:00:00
abstract::A 52-year-old female presented to our out patient department with asymptomatic, hypopigmented lesions on the neck and back since 2 months. There was a history of taking antitubercular treatment for suspected pulmonary tuberculosis 2 years back. On blood investigations, the serum angiotensin converting enzyme levels we...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
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更新日期:2011-07-01 00:00:00
abstract::Pheohyphomycosis is a rare heterogeneous group of mycotic infections caused by dematiaceous (phaeoid) fungi affecting the skin, subcutaneous tissue, and central nervous system. Herein, we report a case of 29-year-old man with innocuous pustule over the right index finger. Examination revealed a subcutaneous swelling w...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.108083
更新日期:2013-03-01 00:00:00
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journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.190128
更新日期:2016-09-01 00:00:00
abstract:INTRODUCTION:Facial angiofibromas (FA) are the most visible cutaneous manifestations in patients with tuberous sclerosis (TS), often resulting in stigmatization of the affected individuals. Recent studies have suggested that topical rapamycin may be an effective treatment for angiofibromas. AIM:To study the safety and...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.174087
更新日期:2016-01-01 00:00:00
abstract:Background:In our hospital setup located in the tropical zone, during each summer, we frequently come across a unique eczematous dermatosis among elderly females that typically occur in summer. Aims and Objectives:We carried out this study with the objective of studying the demographic and clinical features of this de...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
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journal_title:Indian journal of dermatology
pub_type: 杂志文章
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更新日期:2016-03-01 00:00:00
abstract::Palisaded encapsulated neuroma (PEN) is an infrequent benign cutaneous neural tumor, which usually presents as solitary, asymptomatic, papule or nodule, often localized on the faces, around the orifices, in middle age with no sex preponderance. Rarely, it can be multiple. Both solitary and multiple lesions are not ass...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.119971
更新日期:2013-11-01 00:00:00
abstract::Cutaneous larva migrans (CLM) is characterized by the formation of distinctive, tortuous, and serpentine skin lesions occurring as a result of epidermal burrowing by certain helminthic larvae. Although this condition is usually uneventful, rarely it may result in patchy pulmonary infiltration with peripheral eosinophi...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.177753
更新日期:2016-03-01 00:00:00