Acne in Klinefelter Syndrome-46XY/47XXY Mosaicism?

Abstract:

:Klinefelter syndrome (KFS) is the most common non-heritable sex chromosome anomaly caused by nondisjunction during cell division and contains two or more X chromosomes. More than two third of all cases are homogenous (47XXY) and the remaining are mosaic (46XY/47XXY). Lower limb ulcers are frequently observed and attributed to impaired fibrinolysis. A case of KFS with post acne scars and leg ulcers is presented. The rarity of acne in this syndrome is explained by the phenomenon of mosaicism.

journal_name

Indian J Dermatol

authors

Lakshmi C,Swarnalakshimi S

doi

10.4103/0019-5154.164373

subject

Has Abstract

pub_date

2015-09-01 00:00:00

pages

494-6

issue

5

eissn

0019-5154

issn

1998-3611

pii

IJD-60-494

journal_volume

60

pub_type

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