Abstract:
:The concentration of vitamin E (alpha-tocopherol) was measured in samples of cortex from patients with Alzheimer's disease (AD), fetuses with Down's syndrome (DS), and also in a group of centenarians. The mean tocopherol concentrations in the two patient groups did not differ significantly from appropriate controls. When expressed per lipid the mean tocopherol concentration of the centenarians was greater than that of the controls but this reflected a significant decrease in the lipid concentration of the former group. These results indicate that neither the normal aging processes, Alzheimer's disease, nor the increased in vitro lipid peroxidation reported in fetuses with Down's syndrome result from a gross lack of alpha-tocopherol, or cause a significant depletion of the vitamin.
journal_name
Neurochem Resjournal_title
Neurochemical researchauthors
Metcalfe T,Bowen DM,Muller DPdoi
10.1007/BF00965511subject
Has Abstractpub_date
1989-12-01 00:00:00pages
1209-12issue
12eissn
0364-3190issn
1573-6903journal_volume
14pub_type
杂志文章abstract::The serotoninergic system modulates nociceptive and locomotor spinal cord circuits. Exercise improves motor function and changes dopaminergic, noradrenergic, and serotonergic central systems. However, the direct relationship between serotonin, peripheral nerve lesion and aerobic treadmill exercise has not been studied...
journal_title:Neurochemical research
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journal_title:Neurochemical research
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pub_type: 杂志文章
doi:10.1007/BF00966224
更新日期:1986-10-01 00:00:00
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journal_title:Neurochemical research
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journal_title:Neurochemical research
pub_type: 杂志文章
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更新日期:1984-02-01 00:00:00
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更新日期:2014-07-01 00:00:00
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更新日期:2011-10-01 00:00:00
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journal_title:Neurochemical research
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journal_title:Neurochemical research
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更新日期:2012-04-01 00:00:00
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更新日期:2007-10-01 00:00:00
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更新日期:2016-06-01 00:00:00
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journal_title:Neurochemical research
pub_type: 杂志文章
doi:10.1023/a:1007546600535
更新日期:2000-05-01 00:00:00
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更新日期:2020-09-01 00:00:00
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更新日期:1997-06-01 00:00:00
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更新日期:2021-01-03 00:00:00
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更新日期:2004-09-01 00:00:00
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journal_title:Neurochemical research
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更新日期:2011-01-01 00:00:00
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