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Genome flux and stasis in a five millennium transect of European prehistory.

Abstract：

:The Great Hungarian Plain was a crossroads of cultural transformations that have shaped European prehistory. Here we analyse a 5,000-year transect of human genomes, sampled from petrous bones giving consistently excellent endogenous DNA yields, from 13 Hungarian Neolithic, Copper, Bronze and Iron Age burials including two to high (~22 × ) and seven to ~1 × coverage, to investigate the impact of these on Europe's genetic landscape. These data suggest genomic shifts with the advent of the Neolithic, Bronze and Iron Ages, with interleaved periods of genome stability. The earliest Neolithic context genome shows a European hunter-gatherer genetic signature and a restricted ancestral population size, suggesting direct contact between cultures after the arrival of the first farmers into Europe. The latest, Iron Age, sample reveals an eastern genomic influence concordant with introduced Steppe burial rites. We observe transition towards lighter pigmentation and surprisingly, no Neolithic presence of lactase persistence.

journal_name

Nat Commun

journal_title

Nature communications

authors

Gamba C,Jones ER,Teasdale MD,McLaughlin RL,Gonzalez-Fortes G,Mattiangeli V,Domboróczki L,Kővári I,Pap I,Anders A,Whittle A,Dani J,Raczky P,Higham TF,Hofreiter M,Bradley DG,Pinhasi R

doi

10.1038/ncomms6257

subject

Has Abstract

pub_date

2014-10-21 00:00:00

pages

5257

issn

2041-1723

pii

ncomms6257

journal_volume

5

pub_type

历史文章,杂志文章

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