From guideline to patient: a review of recent recommendations for pharmacotherapy of painful diabetic neuropathy.

Abstract:

:Painful diabetic peripheral neuropathy (DPN) is a common complication of diabetes mellitus, affecting, by some estimates, up to one quarter of diabetic patients. Since 2010, no fewer than 5 major international treatment guidelines for painful DPN have been issued, and there are meaningful differences among them. Duloxetine, pregabalin, gabapentin, and tricyclic antidepressants are the mainstays of treatment, but the choice of which class or agent to use in any given patient should be informed by patient characteristics. This review seeks to describe the differences among the recently issued guidelines, to assess the evidence on which they are based, and to offer insight into the most appropriate treatment choices based on patient characteristics.

authors

Ziegler D,Fonseca V

doi

10.1016/j.jdiacomp.2014.08.008

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

146-56

issue

1

eissn

1056-8727

issn

1873-460X

pii

S1056-8727(14)00254-2

journal_volume

29

pub_type

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