Abstract：
:The purpose of this study was to compare the histologic variability of atheromas resected from patients with various risk factors for vascular disease. Twenty-seven plaques obtained using the Simpson atherectomy catheter were studied. The results of this light and electron microscopic study indicate that patients with diabetes mellitus had increased numbers of smooth muscle cells in their plaques (P less than 0.05) and a trend toward denser, less fatty connective tissue matrix (P less than 0.07) when compared with non-diabetics, and that female diabetics had more smooth muscle cells in their plaques than male diabetics (P less than 0.05). The female patients, regardless of risk factors, had more smooth muscle cells in their plaques than male patients (P less than 0.004). Patients with poor distal runoff had more neovascularization of plaque (P less than 0.001). Tobacco use and age did not have statistically significant correlations with histologic patterns.
journal_name
Atherosclerosisjournal_title
Atherosclerosisauthors
Barbano EF,Newman GE,McCann RL,Hackel DB,Stack RS,Palmos LE,Mikat EMdoi
10.1016/0021-9150(89)90222-0subject
Has Abstractpub_date
1989-08-01 00:00:00pages
183-96issue
2-3eissn
0021-9150issn
1879-1484pii
0021-9150(89)90222-0journal_volume
78pub_type
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